IL87765A0 - L-dopa derivatives and their acid addition salts,process for producing same and pharmaceutical compositions containing them - Google Patents
L-dopa derivatives and their acid addition salts,process for producing same and pharmaceutical compositions containing themInfo
- Publication number
- IL87765A0 IL87765A0 IL87765A IL8776588A IL87765A0 IL 87765 A0 IL87765 A0 IL 87765A0 IL 87765 A IL87765 A IL 87765A IL 8776588 A IL8776588 A IL 8776588A IL 87765 A0 IL87765 A0 IL 87765A0
- Authority
- IL
- Israel
- Prior art keywords
- acid addition
- optionally substituted
- pharmaceutical compositions
- addition salts
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23429987 | 1987-09-18 | ||
JP3126088 | 1988-02-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL87765A0 true IL87765A0 (en) | 1989-02-28 |
Family
ID=26369718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL87765A IL87765A0 (en) | 1987-09-18 | 1988-09-15 | L-dopa derivatives and their acid addition salts,process for producing same and pharmaceutical compositions containing them |
Country Status (12)
Country | Link |
---|---|
US (1) | US4966915A (ja) |
EP (1) | EP0309827B1 (ja) |
JP (1) | JPH02138A (ja) |
KR (1) | KR890005031A (ja) |
CN (1) | CN1032785A (ja) |
AT (1) | ATE71083T1 (ja) |
AU (1) | AU2234088A (ja) |
CA (1) | CA1316180C (ja) |
DE (1) | DE3867403D1 (ja) |
DK (1) | DK517588A (ja) |
IL (1) | IL87765A0 (ja) |
PT (1) | PT88526B (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003217430B2 (en) * | 2002-02-15 | 2008-10-23 | Darpharma, Inc. | Mono-ester and asymmetrically substituted Di-ester pro-drugs of the dopamine D1 receptor agonists |
AU2003293423A1 (en) * | 2002-12-06 | 2004-06-30 | Xenoport, Inc. | Carbidopa prodrugs and uses thereof |
US7471862B2 (en) | 2002-12-19 | 2008-12-30 | Corning Cable Systems, Llc | Dry fiber optic cables and assemblies |
US6970629B2 (en) | 2002-12-19 | 2005-11-29 | Corning Cable Systems Llc | Optical tube assembly having a dry insert and methods of making the same |
US20090190890A1 (en) | 2002-12-19 | 2009-07-30 | Freeland Riley S | Fiber optic cable having a dry insert and methods of making the same |
IL154318A (en) | 2003-02-06 | 2010-05-31 | Sarah Herzog Memorial Hospital | Pharmaceutical compositions for the treatment of movement disorders |
WO2005121070A1 (en) * | 2004-06-04 | 2005-12-22 | Xenoport, Inc. | Levodopa prodrugs, and compositions and uses thereof |
CN101023056B (zh) | 2004-06-04 | 2011-05-25 | 克塞诺波特公司 | 左旋多巴前药、和组合物及其应用 |
EP1959948B1 (en) * | 2005-12-05 | 2012-07-18 | XenoPort, Inc. | Levodopa prodrug mesylate, compositions thereof, and uses thereof |
TW200843731A (en) * | 2006-12-21 | 2008-11-16 | Xenoport Inc | Catechol protected levodopa diester prodrugs, compositions, and methods of use |
JP2011502953A (ja) * | 2006-12-21 | 2011-01-27 | ゼノポート,インコーポレーテッド | ジメチル置換されたレボドパジエステルのプロドラッグ、組成物及び使用方法 |
CA2740017A1 (en) | 2008-10-20 | 2010-04-29 | Xenoport, Inc. | Methods of synthesizing a levodopa ester prodrug |
US8399513B2 (en) | 2008-10-20 | 2013-03-19 | Xenoport, Inc. | Levodopa prodrug mesylate hydrate |
KR101025612B1 (ko) * | 2008-11-10 | 2011-03-30 | 한국해양연구원 | 신규 화합물인 Ramalin 및 그 용도 |
WO2011056240A2 (en) | 2009-11-09 | 2011-05-12 | Xenoport, Inc. | Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use |
MX336187B (es) | 2010-03-04 | 2016-01-07 | Orion Corp | Metodo para tratar el mal de parkinson. |
CN103694127B (zh) * | 2013-12-30 | 2015-04-01 | 上海交通大学 | 链霉菌属菌种所产的化合物及该化合物的制备方法和应用 |
EP3569587A1 (en) | 2014-10-21 | 2019-11-20 | AbbVie Inc. | Intermediates and process for preparing l-dopa diphosphate |
JP6982870B2 (ja) | 2015-05-06 | 2021-12-17 | シンアジャル コーポレイション | 薬物粒子を含有する医薬懸濁液、それらの投与のためのデバイス、およびそれらの使用方法 |
WO2019097120A1 (en) | 2017-11-16 | 2019-05-23 | Orion Corporation | New use and pharmaceutical dosage forms |
US20220213128A1 (en) * | 2021-01-03 | 2022-07-07 | RockGen Therapeutics LLC | L-Dopa Enhanced with a Neuroprotective Agent as a Therapy for Parkinson's Disease |
WO2023064783A1 (en) * | 2021-10-11 | 2023-04-20 | The Johns Hopkins University | Dopa and caffiec acid analogs as novel gcpii inhibitors |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US393923A (en) * | 1888-12-04 | Samuel preston | ||
US2868818A (en) * | 1953-12-15 | 1959-01-13 | Merck & Co Inc | Alpha methyl phenylalanines |
US3725470A (en) * | 1969-05-14 | 1973-04-03 | Hoffmann La Roche | Amino acid derivatives |
CH562199A5 (ja) * | 1970-10-30 | 1975-05-30 | Hoffmann La Roche | |
BE793426A (fr) * | 1971-12-28 | 1973-06-28 | Lannacher Heilmittel G M B H | Derives de phenylalanine |
US3983138A (en) * | 1973-09-25 | 1976-09-28 | Merck & Co., Inc. | Amino acid esters |
US3891696A (en) * | 1973-11-02 | 1975-06-24 | Interx Research Corp | Novel, transient pro-drug forms of l-dopa |
US3939253A (en) * | 1973-11-02 | 1976-02-17 | Interx Research Corporation | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease |
US4401676A (en) * | 1977-06-01 | 1983-08-30 | Merck & Co., Inc. | Novel α-amino acids |
US4311706A (en) * | 1980-01-22 | 1982-01-19 | Interx Research Corporation | Novel dopa/dopamine prodrugs |
-
1988
- 1988-09-10 JP JP63227086A patent/JPH02138A/ja active Granted
- 1988-09-14 CA CA000577320A patent/CA1316180C/en not_active Expired - Fee Related
- 1988-09-15 IL IL87765A patent/IL87765A0/xx unknown
- 1988-09-16 AT AT88115183T patent/ATE71083T1/de active
- 1988-09-16 KR KR1019880012032A patent/KR890005031A/ko not_active Application Discontinuation
- 1988-09-16 US US07/245,348 patent/US4966915A/en not_active Expired - Fee Related
- 1988-09-16 DE DE8888115183T patent/DE3867403D1/de not_active Expired - Fee Related
- 1988-09-16 PT PT88526A patent/PT88526B/pt not_active IP Right Cessation
- 1988-09-16 EP EP88115183A patent/EP0309827B1/en not_active Expired - Lifetime
- 1988-09-16 AU AU22340/88A patent/AU2234088A/en not_active Abandoned
- 1988-09-16 DK DK517588A patent/DK517588A/da not_active Application Discontinuation
- 1988-09-17 CN CN88107165A patent/CN1032785A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH02138A (ja) | 1990-01-05 |
CN1032785A (zh) | 1989-05-10 |
AU2234088A (en) | 1989-03-23 |
DE3867403D1 (de) | 1992-02-13 |
KR890005031A (ko) | 1989-05-11 |
US4966915A (en) | 1990-10-30 |
DK517588A (da) | 1989-03-19 |
EP0309827B1 (en) | 1992-01-02 |
JPH0541626B2 (ja) | 1993-06-24 |
EP0309827A1 (en) | 1989-04-05 |
CA1316180C (en) | 1993-04-13 |
DK517588D0 (da) | 1988-09-16 |
PT88526A (pt) | 1988-10-01 |
PT88526B (pt) | 1992-11-30 |
ATE71083T1 (de) | 1992-01-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL87765A0 (en) | L-dopa derivatives and their acid addition salts,process for producing same and pharmaceutical compositions containing them | |
CS556587A2 (en) | Process for preparing aminoderivatives | |
HUT46708A (en) | Process for producing heterocyclic ketones and pharmaceutical compositions containing them as active components | |
AU1400801A (en) | Aralkyl-1,2-diamines having calcimimetic activity and preparation mode | |
HUT50337A (en) | Process for producing benzoxazine derivatives and pharmaceutical compositions comprising the compounds | |
AU608643B2 (en) | Novel derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them | |
ZA891769B (en) | Heterocyclic compounds | |
ES8304125A1 (es) | "un procedimiento para la preparacion de nuevos derivados de oxodiazolopirimidina". | |
HUT43586A (en) | Process for production of derivatives and salts of 8-tiotetrahydro-quinoline and medical preparatives containing thereof as active substance | |
PT87310A (pt) | Process for the preparation of thiadiazole guanidines |