IL73159D0 - Carboxyalkenamidocephalosporines,process for the preparation thereof and methods for the use thereof - Google Patents

Carboxyalkenamidocephalosporines,process for the preparation thereof and methods for the use thereof

Info

Publication number
IL73159D0
IL73159D0 IL73159A IL7315984A IL73159D0 IL 73159 D0 IL73159 D0 IL 73159D0 IL 73159 A IL73159 A IL 73159A IL 7315984 A IL7315984 A IL 7315984A IL 73159 D0 IL73159 D0 IL 73159D0
Authority
IL
Israel
Prior art keywords
carboxyalkenamidocephalosporines
preparation
methods
process
use
Prior art date
Application number
IL73159A
Other versions
IL73159A (en
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP58186601A priority Critical patent/JPH0251555B2/ja
Priority to JP59018563A priority patent/JPS60163884A/en
Priority to JP59100890A priority patent/JPH0780892B2/en
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of IL73159D0 publication Critical patent/IL73159D0/en
Publication of IL73159A publication Critical patent/IL73159A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/081,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
IL73159A 1983-10-04 1984-10-04 Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereof IL73159A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP58186601A JPH0251555B2 (en) 1983-10-04 1983-10-04
JP59018563A JPS60163884A (en) 1984-02-03 1984-02-03 Carboxyalkenamidocephalosporin
JP59100890A JPH0780892B2 (en) 1984-05-18 1984-05-18 Carboxy alkene amides ceph Aros porin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL84653A IL84653A (en) 1983-10-04 1984-10-04 Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof
IL84653A IL84653D0 (en) 1983-10-04 1987-11-27 Carboxybutenoic acids and processes for the preparation thereof

Publications (2)

Publication Number Publication Date
IL73159D0 true IL73159D0 (en) 1985-01-31
IL73159A IL73159A (en) 1990-08-31

Family

ID=27282263

Family Applications (3)

Application Number Title Priority Date Filing Date
IL84653A IL84653A (en) 1983-10-04 1984-10-04 Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof
IL73159A IL73159A (en) 1983-10-04 1984-10-04 Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereof
IL84653A IL84653D0 (en) 1983-10-04 1987-11-27 Carboxybutenoic acids and processes for the preparation thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL84653A IL84653A (en) 1983-10-04 1984-10-04 Amino-alpha-carboxyethylidenethiazoleacetic acid derivatives and processes for the preparation thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL84653A IL84653D0 (en) 1983-10-04 1987-11-27 Carboxybutenoic acids and processes for the preparation thereof

Country Status (22)

Country Link
US (3) US4634697A (en)
EP (1) EP0136721B1 (en)
KR (2) KR880002376B1 (en)
AR (1) AR242392A1 (en)
AT (1) AT99311T (en)
AU (2) AU575854B2 (en)
CA (2) CA1272713C (en)
DE (3) DE3486259T2 (en)
DK (1) DK171043B1 (en)
ES (3) ES8604602A1 (en)
FI (1) FI82057C (en)
GB (3) GB2154580B (en)
GR (1) GR80544B (en)
HU (1) HU193298B (en)
IE (1) IE57744B1 (en)
IL (3) IL84653A (en)
MX (1) MX174328B (en)
NL (1) NL940013I2 (en)
NO (2) NO173238C (en)
NZ (2) NZ218741A (en)
PH (2) PH20223A (en)
PT (1) PT79287A (en)

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AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
JP2501785B2 (en) * 1984-07-09 1996-05-29 明治製菓株式会社 New Sefuarosuporin-based compounds
JPH0587512B2 (en) * 1984-07-12 1993-12-16 Shionogi Seiyaku Kk
JPH0577670B2 (en) * 1984-08-24 1993-10-27 Shionogi Seiyaku Kk
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
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AT396652B (en) * 1986-07-02 1993-11-25 Shionogi & Co Process for the preparation of hard gelatin capsule compositions
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
DE3745094B4 (en) * 1986-07-02 2004-12-30 Shionogi & Co., Ltd. New stable hydrate of 7-butenoyl:amino- cephalosporin derivs. - esp. formulated in soft gelatin capsules sealed with gelatin layer
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
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US5079242A (en) * 1987-03-11 1992-01-07 Pfizer Inc. Substituted 3-cephem compounds as antibacterial agents
US4820832A (en) * 1988-03-23 1989-04-11 Eli Lilly And Company Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
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IL163666D0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US8225458B1 (en) 2001-07-13 2012-07-24 Hoffberg Steven M Intelligent door restraint
US20050152852A1 (en) * 2002-05-27 2005-07-14 Morinaga & Co., Ltd. Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria
US8313776B2 (en) * 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2006528190A (en) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション Antibiotics, their use and creating
CA2533358C (en) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
EP1653925A1 (en) * 2003-08-11 2006-05-10 Advancis Pharmaceutical Corporation Robust pellet
WO2005016278A2 (en) * 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
EP1658034A4 (en) * 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc Antibiotic product, use and formulation thereof
WO2005027877A1 (en) * 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2550983C (en) * 2003-12-24 2013-09-17 Advancis Pharmaceutical Corporation Enhanced absorption of modified release dosage forms
EP1771158A4 (en) * 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp Tablet for pulsed delivery
US20110104109A1 (en) * 2005-07-13 2011-05-05 Frank Bennett Tetracyclic indole derivatives and their use for treating or preventing viral infections
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
EP2064180B1 (en) 2006-12-22 2016-07-13 Merck Sharp & Dohme Corp. 4,5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections
WO2008136815A2 (en) 2006-12-22 2008-11-13 Schering Corporation 5, 6-ring annulated indole derivatives and use thereof
CN101611002A (en) * 2006-12-22 2009-12-23 先灵公司 4, 5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
BRPI0815811A2 (en) 2007-08-29 2015-02-18 Schering Corp substituted indole derivatives and methods of use thereof
CA2697375A1 (en) * 2007-08-29 2009-03-12 Schering Corporation 2, 3-substituted indole derivatives for treating viral infections
JP5258889B2 (en) * 2007-08-29 2013-08-07 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 2,3-substituted azaindole derivatives for the treatment of viral infections
CA2705586A1 (en) * 2007-11-16 2009-05-22 Schering Corporation 3-heterocyclic substituted indole derivatives and methods of use thereof
CN102317285A (en) * 2007-11-16 2012-01-11 先灵公司 3-aminosulfonyl substituted indole derivatives and methods of use thereof
US8901139B2 (en) * 2008-06-13 2014-12-02 Merck Sharp & Dohme Corp. Tricyclic indole derivatives and methods of use thereof
CA2734487A1 (en) 2008-08-20 2010-02-25 Southern Research Institute Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
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AU2009282567B2 (en) 2008-08-20 2014-10-02 Merck Sharp & Dohme Corp. Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
US8715638B2 (en) 2008-08-20 2014-05-06 Merck Sharp & Dohme Corp. Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
WO2010138791A1 (en) 2009-05-29 2010-12-02 Schering Corporation Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c
CA2782024A1 (en) 2009-11-25 2011-06-03 Schering Corporation Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
AU2010341537A1 (en) 2009-12-22 2012-08-09 Merck Sharp & Dohme Corp. Fused Tricyclic Compounds and methods of use thereof for the treatment of viral diseases
EP2536410B1 (en) 2010-02-18 2015-09-23 Merck Sharp & Dohme Corp. Substituted pyrimidine derivatives and their use in treating viral infections
SG183526A1 (en) 2010-03-09 2012-09-27 Merck Sharp & Dohme Fused tricyclic silyl compounds and methods of use thereof for the treatment of viral diseases
CN101824004B (en) * 2010-04-30 2012-02-22 黄山市歙县宏辉化工有限公司 Synthesization technique for ceftibuten side chain
WO2011139253A2 (en) 2010-05-04 2011-11-10 Mahmut Bilgic Pharmaceutical compositions comprising ceftibuten
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US9254292B2 (en) 2010-09-29 2016-02-09 Merck Sharp & Dohme Corp. Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
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WO2013033900A1 (en) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
WO2013033899A1 (en) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
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GB966131A (en) * 1959-04-07 1964-08-06 Union Carbide Corp Process for the preparation of organic compounds
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Also Published As

Publication number Publication date
DE3486259D1 (en) 1994-02-10
ES8700222A1 (en) 1986-11-16
EP0136721A2 (en) 1985-04-10
NO176567B (en) 1995-01-16
DK474584A (en) 1985-04-05
NO843956L (en) 1985-04-09
NZ209634A (en) 1988-07-28
AR242392A1 (en) 1993-03-31
NO853806L (en) 1985-04-09
ES547300D0 (en)
AT99311T (en) 1994-01-15
AU1619488A (en) 1988-08-11
GB8700123D0 (en) 1987-02-11
ES8604602A1 (en) 1986-02-01
NO173238B (en) 1993-08-09
ES547301D0 (en)
CA1272713C (en) 1990-08-14
IE57744B1 (en) 1993-03-24
AU3330084A (en) 1985-05-09
FI82057B (en) 1990-09-28
US4912224A (en) 1990-03-27
NZ218741A (en) 1988-07-28
FI843871A (en)
MX174328B (en) 1994-05-09
GB2154580A (en) 1985-09-11
FI843871A0 (en) 1984-10-02
IL73159A (en) 1990-08-31
KR850002989A (en) 1985-05-28
IL84653A (en) 1990-08-31
NO173238C (en) 1993-11-17
IE842524L (en) 1985-04-04
HUT36129A (en) 1985-08-28
KR880002376B1 (en) 1988-11-03
KR880002684B1 (en) 1988-12-20
FI843871L (en) 1985-04-05
AU575854B2 (en) 1988-08-11
ES547301A0 (en) 1986-03-16
ES536502D0 (en)
ES547300A0 (en) 1986-11-16
DK171043B1 (en) 1996-04-29
PH20223A (en) 1986-10-23
GR80544B (en) 1985-02-05
HU193298B (en) 1987-09-28
GB2190914B (en) 1988-08-17
US4634697A (en) 1987-01-06
DE3486259T2 (en) 1994-07-21
GB2198727B (en) 1988-11-16
FI843871D0 (en)
ES536502A0 (en) 1986-02-01
DE136721T1 (en) 1985-08-29
IL84653D0 (en) 1988-04-29
CA1272713A (en) 1990-08-14
NL940013I1 (en) 1994-08-16
NL940013I2 (en) 1999-06-01
GB8726623D0 (en) 1987-12-16
EP0136721B1 (en) 1993-12-29
GB8424923D0 (en) 1984-11-07
PH21766A (en) 1988-02-18
GB2198727A (en) 1988-06-22
GB2190914A (en) 1987-12-02
FI82057C (en) 1991-01-10
AU601842B2 (en) 1990-09-20
NO176567C (en) 1995-04-26
PT79287A (en) 1984-11-01
US4748170A (en) 1988-05-31
CA1238910A1 (en) 1988-07-05
ES8605278A1 (en) 1986-03-16
EP0136721A3 (en) 1986-01-22
DK474584D0 (en) 1984-10-03
GB2154580B (en) 1988-08-17

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