IL31789D0 - N-hydroxyphenyl-n'-phenylureas,their manufacture and use - Google Patents

N-hydroxyphenyl-n'-phenylureas,their manufacture and use

Info

Publication number
IL31789D0
IL31789D0 IL3178969A IL3178969A IL31789D0 IL 31789 D0 IL31789 D0 IL 31789D0 IL 3178969 A IL3178969 A IL 3178969A IL 3178969 A IL3178969 A IL 3178969A IL 31789 D0 IL31789 D0 IL 31789D0
Authority
IL
Israel
Prior art keywords
phenylureas
hydroxyphenyl
manufacture
Prior art date
Application number
IL3178969A
Other versions
IL31789A (en
Original Assignee
Ciba Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH416768 priority Critical
Application filed by Ciba Ltd filed Critical Ciba Ltd
Publication of IL31789D0 publication Critical patent/IL31789D0/en
Publication of IL31789A publication Critical patent/IL31789A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
IL3178969A 1968-03-21 1969-03-12 N-hydroxyphenyl-n'-phenylureas,their manufacture and use IL31789A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH416768 1968-03-21

Publications (2)

Publication Number Publication Date
IL31789D0 true IL31789D0 (en) 1969-05-28
IL31789A IL31789A (en) 1972-11-28

Family

ID=4271046

Family Applications (1)

Application Number Title Priority Date Filing Date
IL3178969A IL31789A (en) 1968-03-21 1969-03-12 N-hydroxyphenyl-n'-phenylureas,their manufacture and use

Country Status (8)

Country Link
US (1) US3689550A (en)
BE (1) BE730185A (en)
DE (1) DE1912553A1 (en)
FR (1) FR2004393A1 (en)
GB (1) GB1233125A (en)
IL (1) IL31789A (en)
NL (1) NL6904320A (en)
SE (1) SE370866B (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988294A (en) * 1974-03-11 1976-10-26 R. T. Vanderbilt Company, Inc. Surface coating compositions containing antimicrobic ureas
DE2928485A1 (en) * 1979-07-14 1981-01-29 Bayer Ag USE OF UREA DERIVATIVES AS A MEDICINAL PRODUCT IN THE TREATMENT OF FATTY METABOLISM DISORDERS
DK41193D0 (en) * 1993-04-07 1993-04-07 Neurosearch As ion channel openers
KR19980701879A (en) * 1995-02-02 1998-06-25 피터 기딩스 Indole derivatives as 5-hydroxytryptamine receptor antagonists
US6211373B1 (en) 1996-03-20 2001-04-03 Smithkline Beecham Corporation Phenyl urea antagonists of the IL-8 receptor
US6262113B1 (en) 1996-03-20 2001-07-17 Smithkline Beecham Corporation IL-8 receptor antagonists
JPH11503110A (en) * 1995-02-17 1999-03-23 スミスクライン・ビーチャム・コーポレイション IL-8 receptor antagonist
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists
US6005008A (en) * 1996-02-16 1999-12-21 Smithkline Beecham Corporation IL-8 receptor antagonists
CA2197364A1 (en) * 1996-02-15 1997-08-16 Toshikazu Suzuki Phenol compound and process for preparing the same
JP2000514049A (en) * 1996-06-27 2000-10-24 スミスクライン・ビーチャム・コーポレイション IL-8 receptor antagonist
WO1997049286A1 (en) 1996-06-27 1997-12-31 Smithkline Beecham Corporation Il-8 receptor antagonists
US6344476B1 (en) * 1997-05-23 2002-02-05 Bayer Corporation Inhibition of p38 kinase activity by aryl ureas
US7329670B1 (en) * 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US7517880B2 (en) * 1997-12-22 2009-04-14 Bayer Pharmaceuticals Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US20080300281A1 (en) * 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
EP1107948A4 (en) * 1998-08-28 2002-01-02 Smithkline Beecham An improved synthesis of 3-hydroxy-4-amino-benzonitrile
US20080269265A1 (en) * 1998-12-22 2008-10-30 Scott Miller Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
RU2319693C9 (en) 1999-01-13 2008-08-20 Байер Копэрейшн Derivatives of urea (variants), pharmaceutical composition (variants) and method for treatment of diseases associated with cancer cells growth (variants)
EP2298311B1 (en) 1999-01-13 2012-05-09 Bayer HealthCare LLC w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
US7928239B2 (en) 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
WO2000042012A1 (en) 1999-01-13 2000-07-20 Bayer Corporation φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
PT1450799E (en) * 2001-12-03 2007-01-31 Bayer Pharmaceuticals Corp Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers
AU2003210969A1 (en) * 2002-02-11 2003-09-04 Bayer Corporation Aryl ureas with raf kinase and angiogenesis inhibiting activity
SI1478358T1 (en) 2002-02-11 2013-09-30 Bayer Healthcare Llc Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis
AT529406T (en) 2002-02-11 2011-11-15 Bayer Healthcare Llc Aryl ureas as kinase inhibitors
US20030216396A1 (en) 2002-02-11 2003-11-20 Bayer Corporation Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
MY143477A (en) * 2002-10-29 2011-05-31 Smithkline Beecham Corp Il-8 receptor antagonists
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
DE602004007382T2 (en) * 2003-05-20 2008-04-17 Bayer Pharmaceuticals Corp., West Haven DIARYL UREAS FOR PDGFR MEDIATED DISEASES
JP4777887B2 (en) 2003-07-23 2011-09-21 バイエル、ファーマシューテイカルズ、コーポレイション Fluoro-substituted omegacarboxyaryl diphenylureas for the treatment and prevention of diseases and conditions
CA2632925A1 (en) * 2005-12-13 2007-06-21 Arpida Ag Diphenyl urea derivatives
EP2010180A4 (en) * 2006-04-21 2010-10-13 Glaxosmithkline Llc Il-8 receptor antagonists
PT2009992E (en) * 2006-04-21 2012-09-06 Glaxosmithkline Llc Il-8 receptor antagonists
PE20080943A1 (en) * 2006-06-23 2008-09-27 Smithkline Beecham Corp Toluenesulfonate salt of 1,1-dimethylethyl 4 - {[6-chloro-3 - ({[(2-chloro-3-fluorophenyl) amino] carbonyl} amino) -2-hydroxyphenyl] sulfonyl} -1-piperazinecarboxylate antagonist il-8 receptor
EP2701699B1 (en) 2011-04-28 2019-10-16 The Broad Institute, Inc. Inhibitors of histone deacetylase
JP6337255B2 (en) 2012-07-27 2018-06-06 ザ ブロード インスティテュート,インコーポレーテッドThe Broad Institute,Inc. Inhibitors of histone deacetylase
WO2014100438A1 (en) 2012-12-20 2014-06-26 The Broad Institute, Inc. Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2745874A (en) * 1953-06-18 1956-05-15 Geigy Ag J R Insecticidal derivatives of diphenyl urea
NL193403A (en) * 1953-12-22 1924-02-17
NL277504A (en) * 1961-04-21
FR1457172A (en) * 1964-12-12 1966-10-28 Ferrania Spa Process for the production of color photographic images and corresponding photographic material

Also Published As

Publication number Publication date
US3689550A (en) 1972-09-05
GB1233125A (en) 1971-05-26
DE1912553A1 (en) 1969-10-09
BE730185A (en) 1969-09-22
FR2004393A1 (en) 1969-11-21
NL6904320A (en) 1969-09-23
SE370866B (en) 1974-11-04
IL31789A (en) 1972-11-28

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