IL313729A - Gap junction modulators and their use for the treatment of age-related macular degeneration - Google Patents

Gap junction modulators and their use for the treatment of age-related macular degeneration

Info

Publication number
IL313729A
IL313729A IL313729A IL31372924A IL313729A IL 313729 A IL313729 A IL 313729A IL 313729 A IL313729 A IL 313729A IL 31372924 A IL31372924 A IL 31372924A IL 313729 A IL313729 A IL 313729A
Authority
IL
Israel
Prior art keywords
compound
treatment
prevention according
amd
retinal
Prior art date
Application number
IL313729A
Other languages
English (en)
Hebrew (he)
Inventor
Ulrik Mouritzen
Bradford Young
Original Assignee
Breye Therapeutics Aps
Ulrik Mouritzen
Bradford Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Breye Therapeutics Aps, Ulrik Mouritzen, Bradford Young filed Critical Breye Therapeutics Aps
Publication of IL313729A publication Critical patent/IL313729A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL313729A 2021-12-22 2022-12-21 Gap junction modulators and their use for the treatment of age-related macular degeneration IL313729A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163292783P 2021-12-22 2021-12-22
PCT/EP2022/087342 WO2023118366A1 (en) 2021-12-22 2022-12-21 Gap junction modulators and their use for the treatment of age-related macular degeneration

Publications (1)

Publication Number Publication Date
IL313729A true IL313729A (en) 2024-08-01

Family

ID=84981302

Family Applications (1)

Application Number Title Priority Date Filing Date
IL313729A IL313729A (en) 2021-12-22 2022-12-21 Gap junction modulators and their use for the treatment of age-related macular degeneration

Country Status (9)

Country Link
US (1) US20250018002A1 (https=)
EP (1) EP4452260B1 (https=)
JP (1) JP2025500123A (https=)
CN (1) CN118450892A (https=)
CA (1) CA3240515A1 (https=)
DK (1) DK4452260T3 (https=)
FI (1) FI4452260T3 (https=)
IL (1) IL313729A (https=)
WO (1) WO2023118366A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202310195D0 (en) * 2023-07-03 2023-08-16 Hastings Nataly Method for mitigating symptoms of neurological condition and a system therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6259296A (ja) 1985-09-10 1987-03-14 Green Cross Corp:The ペプタイド誘導体
IL157447A0 (en) 2001-02-22 2004-03-28 Zealand Pharma As Zealand Phar New medical uses of intercellular communication facilitating compounds
UA96283C2 (uk) 2005-12-23 2011-10-25 Зіланд Фарма А/С Модифіковані міметики лізину
PL2468724T3 (pl) 2006-12-21 2016-05-31 Zealand Pharma As Synteza związków pirolidynowych
JP6989864B2 (ja) * 2017-05-05 2022-02-03 ジーランド ファーマ,アー/エス ギャップ結合細胞間コミュニケーションモジュレータ及び糖尿病性眼疾患の治療のためのそれらの使用

Also Published As

Publication number Publication date
WO2023118366A1 (en) 2023-06-29
CA3240515A1 (en) 2023-06-29
US20250018002A1 (en) 2025-01-16
EP4452260B1 (en) 2026-01-28
EP4452260A1 (en) 2024-10-30
JP2025500123A (ja) 2025-01-09
FI4452260T3 (fi) 2026-03-30
CN118450892A (zh) 2024-08-06
DK4452260T3 (da) 2026-03-30

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