IL308457A - Process for the preparation of benzoxazepin oxazolidinone compounds - Google Patents
Process for the preparation of benzoxazepin oxazolidinone compoundsInfo
- Publication number
- IL308457A IL308457A IL308457A IL30845723A IL308457A IL 308457 A IL308457 A IL 308457A IL 308457 A IL308457 A IL 308457A IL 30845723 A IL30845723 A IL 30845723A IL 308457 A IL308457 A IL 308457A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- oxazolidinone compounds
- benzoxazepin oxazolidinone
- benzoxazepin
- compounds
- Prior art date
Links
- KVQCNKSKFIZOKW-UHFFFAOYSA-N O1C(NCC1)=O.O1N=CC=CC2=C1C=CC=C2 Chemical class O1C(NCC1)=O.O1N=CC=CC2=C1C=CC=C2 KVQCNKSKFIZOKW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
- C07C303/06—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with sulfuric acid or sulfur trioxide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/72—Copper
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C313/02—Sulfinic acids; Derivatives thereof
- C07C313/06—Sulfinamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163194382P | 2021-05-28 | 2021-05-28 | |
| PCT/US2022/031243 WO2022251567A1 (en) | 2021-05-28 | 2022-05-27 | Process for the preparation of benzoxazepin oxazolidinone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL308457A true IL308457A (en) | 2024-01-01 |
Family
ID=82156627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL308457A IL308457A (en) | 2021-05-28 | 2022-05-27 | Process for the preparation of benzoxazepin oxazolidinone compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20240166595A1 (en) |
| EP (1) | EP4347574A1 (en) |
| JP (1) | JP2024520479A (en) |
| KR (1) | KR20240013791A (en) |
| CN (1) | CN117377660A (en) |
| AR (1) | AR125993A1 (en) |
| AU (1) | AU2022282440A1 (en) |
| BR (1) | BR112023024764A2 (en) |
| CA (1) | CA3220273A1 (en) |
| IL (1) | IL308457A (en) |
| MX (1) | MX2023013919A (en) |
| TW (1) | TW202313563A (en) |
| WO (1) | WO2022251567A1 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY184074A (en) | 2009-09-28 | 2021-03-17 | Hoffmann La Roche | Benzoxazepin p13k inhibitors compounds and methods of use |
| DK3317284T3 (en) | 2015-07-02 | 2020-01-13 | H Hoffmann La Roche Ag | Benzoxazepine-oxazolidinone compounds and methods of use |
| PL3555107T3 (en) | 2016-12-15 | 2021-07-05 | F. Hoffmann-La Roche Ag | Process for the preparation of (s)-2-((2-((s)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide |
| CN114835729B (en) * | 2018-05-30 | 2024-05-31 | 江苏豪森药业集团有限公司 | Inhibitor containing tricyclic derivatives, preparation method and application thereof |
| CN109265408B (en) * | 2018-12-11 | 2020-09-01 | 上海皓元生物医药科技有限公司 | Synthesis method of difluoromethyl substituted oxan-2-ketone |
-
2022
- 2022-05-27 AR ARP220101413A patent/AR125993A1/en unknown
- 2022-05-27 KR KR1020237044742A patent/KR20240013791A/en unknown
- 2022-05-27 CN CN202280037407.4A patent/CN117377660A/en active Pending
- 2022-05-27 AU AU2022282440A patent/AU2022282440A1/en active Pending
- 2022-05-27 JP JP2023573037A patent/JP2024520479A/en active Pending
- 2022-05-27 BR BR112023024764A patent/BR112023024764A2/en unknown
- 2022-05-27 WO PCT/US2022/031243 patent/WO2022251567A1/en active Application Filing
- 2022-05-27 TW TW111119945A patent/TW202313563A/en unknown
- 2022-05-27 IL IL308457A patent/IL308457A/en unknown
- 2022-05-27 CA CA3220273A patent/CA3220273A1/en active Pending
- 2022-05-27 EP EP22732817.6A patent/EP4347574A1/en active Pending
- 2022-05-27 MX MX2023013919A patent/MX2023013919A/en unknown
-
2023
- 2023-11-27 US US18/519,529 patent/US20240166595A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN117377660A (en) | 2024-01-09 |
| WO2022251567A1 (en) | 2022-12-01 |
| MX2023013919A (en) | 2023-12-08 |
| AR125993A1 (en) | 2023-08-30 |
| CA3220273A1 (en) | 2022-12-01 |
| TW202313563A (en) | 2023-04-01 |
| JP2024520479A (en) | 2024-05-24 |
| KR20240013791A (en) | 2024-01-30 |
| US20240166595A1 (en) | 2024-05-23 |
| BR112023024764A2 (en) | 2024-02-15 |
| EP4347574A1 (en) | 2024-04-10 |
| AU2022282440A1 (en) | 2023-11-16 |
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