IL268923A - Pharmacologically active alicyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives - Google Patents
Pharmacologically active alicyclic-substituted pyrazolo[1,5-a]pyrimidine derivativesInfo
- Publication number
- IL268923A IL268923A IL26892319A IL26892319A IL268923A IL 268923 A IL268923 A IL 268923A IL 26892319 A IL26892319 A IL 26892319A IL 26892319 A IL26892319 A IL 26892319A IL 268923 A IL268923 A IL 268923A
- Authority
- IL
- Israel
- Prior art keywords
- pharmacologically active
- pyrimidine derivatives
- substituted pyrazolo
- active alicyclic
- alicyclic
- Prior art date
Links
- LDIJKUBTLZTFRG-UHFFFAOYSA-N pyrazolo[1,5-a]pyrimidine Chemical class N1=CC=CN2N=CC=C21 LDIJKUBTLZTFRG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU1700108A HU231058B1 (en) | 2017-03-13 | 2017-03-13 | Pharmacologically active alicyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives |
| PCT/IB2018/051599 WO2018167630A1 (en) | 2017-03-13 | 2018-03-12 | PHARMACOLOGICALLY ACTIVE ALICYCLIC-SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL268923A true IL268923A (en) | 2019-10-31 |
Family
ID=89992389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL26892319A IL268923A (en) | 2017-03-13 | 2019-08-26 | Pharmacologically active alicyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US11026946B2 (en) |
| EP (1) | EP3596080B1 (en) |
| JP (1) | JP7153662B2 (en) |
| KR (1) | KR20190127779A (en) |
| CN (1) | CN110431142A (en) |
| AR (1) | AR111176A1 (en) |
| AU (1) | AU2018235266B2 (en) |
| BR (1) | BR112019018843A2 (en) |
| CA (1) | CA3056185A1 (en) |
| CL (1) | CL2019002601A1 (en) |
| CO (1) | CO2019010120A2 (en) |
| CY (1) | CY1124708T1 (en) |
| DK (1) | DK3596080T3 (en) |
| EA (1) | EA038756B1 (en) |
| EC (1) | ECSP19072975A (en) |
| ES (1) | ES2893824T3 (en) |
| GE (1) | GEP20217256B (en) |
| HR (1) | HRP20211850T1 (en) |
| HU (2) | HU231058B1 (en) |
| IL (1) | IL268923A (en) |
| LT (1) | LT3596080T (en) |
| MX (1) | MX2019011000A (en) |
| MY (1) | MY195262A (en) |
| PE (1) | PE20191646A1 (en) |
| PH (1) | PH12019501968A1 (en) |
| PL (1) | PL3596080T3 (en) |
| PT (1) | PT3596080T (en) |
| RS (1) | RS62533B1 (en) |
| SG (1) | SG11201907864YA (en) |
| SI (1) | SI3596080T1 (en) |
| UA (1) | UA124783C2 (en) |
| WO (1) | WO2018167630A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU231057B1 (en) | 2017-03-13 | 2020-04-28 | Richter Gedeon Nyrt | Pharmacologically active aryl-substituted pyrazolo[1,5-a]pyrimidine derivatives |
| CA3056076A1 (en) | 2017-03-13 | 2018-09-20 | Abide Therapeutics, Inc. | A substituted-heterocyclic-c(o)o-(substituted pyridin-3-yl)compound and its use as a dual magl and faah inhibitor |
| TWI901650B (en) | 2020-03-26 | 2025-10-21 | 匈牙利商羅特格登公司 | NAPHTHYRIDINE AND PYRIDO〔3,4-c〕PYRIDAZINE DERIVATIVES AS GAMMA-AMINOBUTYRIC ACID A RECEPTOR SUBUNIT ALPHA 5 RECEPTOR MODULATORS |
| EP4192833B1 (en) * | 2020-08-05 | 2026-01-21 | Richter Gedeon Nyrt. | Pharmacologically active heterocyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives |
| HU231691B1 (en) | 2021-09-29 | 2025-10-28 | Richter Gedeon Nyrt | GABAA ALPHA5 receptor modulatory bicyclic amine derivatives |
| CN115872095A (en) * | 2022-11-28 | 2023-03-31 | 南通三鑫车灯配件有限公司 | Production line circulation device for automobile lamp reflector |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005001696T2 (en) | 2004-03-02 | 2008-04-10 | F. Hoffmann-La Roche Ag | 4- (SULFANYLPYRIMIDIN-4-YLMETHYL) MORPHOLIN DERIVATIVES AND RELATED COMPOUNDS AS GABA RECEPTOR LIGANDS FOR THE TREATMENT OF ANXIETY, DEPRESSION AND EPILEPSY |
| GB0512844D0 (en) | 2005-06-23 | 2005-08-03 | Novartis Ag | Organic compounds |
| KR100753017B1 (en) * | 2006-05-25 | 2007-08-30 | 한국화학연구원 | For the treatment of brain diseases such as arthritis, atopic dermatitis, cancers including leukemia and Alzheimer's, depression or memory loss, including 7- (3,4-diakoxyphenyl) -pyrazolo [1,5-a] pyrimidine compounds, and Pharmaceutical Compositions for Prevention |
| EP2271646A1 (en) * | 2008-03-31 | 2011-01-12 | Takeda Pharmaceutical Company Limited | Apoptosis signal-regulating kinase 1 inhibitors |
| TWI648281B (en) | 2013-10-17 | 2019-01-21 | 日商安斯泰來製藥股份有限公司 | Sulfur-containing bicyclic compound |
| US9828381B2 (en) * | 2015-04-20 | 2017-11-28 | AbbVie Deutschland GmbH & Co. KG | Substituted pyrazolopyrimidines and method of use |
| JP2018199623A (en) * | 2015-10-22 | 2018-12-20 | 大正製薬株式会社 | Nitrogen-containing fused heterocyclic compounds |
| HU231057B1 (en) | 2017-03-13 | 2020-04-28 | Richter Gedeon Nyrt | Pharmacologically active aryl-substituted pyrazolo[1,5-a]pyrimidine derivatives |
-
2017
- 2017-03-13 HU HU1700108A patent/HU231058B1/en not_active IP Right Cessation
-
2018
- 2018-03-12 EP EP18713016.6A patent/EP3596080B1/en active Active
- 2018-03-12 GE GEAP201815192A patent/GEP20217256B/en unknown
- 2018-03-12 DK DK18713016.6T patent/DK3596080T3/en active
- 2018-03-12 MX MX2019011000A patent/MX2019011000A/en unknown
- 2018-03-12 ES ES18713016T patent/ES2893824T3/en active Active
- 2018-03-12 CN CN201880017859.XA patent/CN110431142A/en active Pending
- 2018-03-12 HU HUE18713016A patent/HUE056562T2/en unknown
- 2018-03-12 PL PL18713016T patent/PL3596080T3/en unknown
- 2018-03-12 KR KR1020197028833A patent/KR20190127779A/en not_active Ceased
- 2018-03-12 UA UAA201910328A patent/UA124783C2/en unknown
- 2018-03-12 US US16/493,453 patent/US11026946B2/en active Active
- 2018-03-12 SG SG11201907864YA patent/SG11201907864YA/en unknown
- 2018-03-12 HR HRP20211850TT patent/HRP20211850T1/en unknown
- 2018-03-12 JP JP2019549366A patent/JP7153662B2/en active Active
- 2018-03-12 EA EA201992127A patent/EA038756B1/en unknown
- 2018-03-12 AU AU2018235266A patent/AU2018235266B2/en not_active Ceased
- 2018-03-12 MY MYPI2019004947A patent/MY195262A/en unknown
- 2018-03-12 RS RS20211334A patent/RS62533B1/en unknown
- 2018-03-12 SI SI201830495T patent/SI3596080T1/en unknown
- 2018-03-12 BR BR112019018843A patent/BR112019018843A2/en not_active Application Discontinuation
- 2018-03-12 PT PT18713016T patent/PT3596080T/en unknown
- 2018-03-12 LT LTEPPCT/IB2018/051599T patent/LT3596080T/en unknown
- 2018-03-12 WO PCT/IB2018/051599 patent/WO2018167630A1/en not_active Ceased
- 2018-03-12 CA CA3056185A patent/CA3056185A1/en active Pending
- 2018-03-12 PE PE2019001773A patent/PE20191646A1/en unknown
- 2018-03-13 AR ARP180100580A patent/AR111176A1/en unknown
-
2019
- 2019-08-26 IL IL26892319A patent/IL268923A/en unknown
- 2019-08-27 PH PH12019501968A patent/PH12019501968A1/en unknown
- 2019-09-12 CL CL2019002601A patent/CL2019002601A1/en unknown
- 2019-09-18 CO CONC2019/0010120A patent/CO2019010120A2/en unknown
- 2019-10-10 EC ECSENADI201972975A patent/ECSP19072975A/en unknown
-
2021
- 2021-11-08 CY CY20211100964T patent/CY1124708T1/en unknown
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