IL257026D0 - Solid state forms of eluxadoline - Google Patents

Solid state forms of eluxadoline

Info

Publication number
IL257026D0
IL257026D0 IL257026A IL25702618A IL257026D0 IL 257026 D0 IL257026 D0 IL 257026D0 IL 257026 A IL257026 A IL 257026A IL 25702618 A IL25702618 A IL 25702618A IL 257026 D0 IL257026 D0 IL 257026D0
Authority
IL
Israel
Prior art keywords
eluxadoline
solid state
state forms
forms
solid
Prior art date
Application number
IL257026A
Other languages
Hebrew (he)
Inventor
Edislav Leksic
Marina Marinkovic
Vitomir Vusak
Sanja Matecic Musanic
Original Assignee
Teva Pharmaceuticals Int Gmbh
Edislav Leksic
Marina Marinkovic
Vitomir Vusak
Sanja Matecic Musanic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201562195959P priority Critical
Priority to US201562250128P priority
Priority to US201562254517P priority
Priority to US201562260972P priority
Priority to PCT/US2016/043678 priority patent/WO2017015606A1/en
Application filed by Teva Pharmaceuticals Int Gmbh, Edislav Leksic, Marina Marinkovic, Vitomir Vusak, Sanja Matecic Musanic filed Critical Teva Pharmaceuticals Int Gmbh
Publication of IL257026D0 publication Critical patent/IL257026D0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
IL257026A 2015-07-23 2018-01-18 Solid state forms of eluxadoline IL257026D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US201562195959P true 2015-07-23 2015-07-23
US201562250128P true 2015-11-03 2015-11-03
US201562254517P true 2015-11-12 2015-11-12
US201562260972P true 2015-11-30 2015-11-30
PCT/US2016/043678 WO2017015606A1 (en) 2015-07-23 2016-07-22 Solid state forms of eluxadoline

Publications (1)

Publication Number Publication Date
IL257026D0 true IL257026D0 (en) 2018-03-29

Family

ID=56561505

Family Applications (1)

Application Number Title Priority Date Filing Date
IL257026A IL257026D0 (en) 2015-07-23 2018-01-18 Solid state forms of eluxadoline

Country Status (4)

Country Link
US (1) US10314819B2 (en)
EP (1) EP3325450A1 (en)
IL (1) IL257026D0 (en)
WO (1) WO2017015606A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017114446A1 (en) * 2015-12-31 2017-07-06 苏州晶云药物科技有限公司 New crystal form of eluxadoline and preparation method thereof
EP3272741A1 (en) * 2016-07-21 2018-01-24 Euticals S.P.A. New stable solvate crystalline forms of eluxadoline
WO2018020450A2 (en) 2016-07-28 2018-02-01 Lupin Limited Process for the preparation of eluxadoline
CZ2016548A3 (en) * 2016-09-07 2018-03-14 Zentiva, K.S. Solid state forms of eluxadoline
EP3573958A1 (en) 2017-01-27 2019-12-04 Quimica Sintetica, S.A. Eluxadoline crystalline forms and processes for their preparation
WO2018138272A1 (en) * 2017-01-27 2018-08-02 Quimica Sintetica, S. A. Eluxadoline crystalline form and process for the preparation thereof
WO2018185664A1 (en) * 2017-04-03 2018-10-11 Sun Pharmaceutical Industries Limited Solvates of eluxadoline
WO2018185711A1 (en) * 2017-04-05 2018-10-11 Sun Pharmaceutical Industries Limited Solvates of eluxadoline
WO2018198101A2 (en) * 2017-04-25 2018-11-01 Sun Pharmaceutical Industries Limited Processes for the preparation of crystalline form of eluxadoline
WO2018229704A1 (en) * 2017-06-15 2018-12-20 Laurus Labs Limited Novel polymorphs of eluxadoline and its solvates, process for its preparation and pharmaceutical composition thereof
WO2019008604A1 (en) 2017-07-07 2019-01-10 Cipla Limited Novel forms of mu-opioid receptor agonist
CA3018321A1 (en) 2017-09-25 2019-03-25 Apotex Inc. Novel crystalline form of eluxadoline

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE029852T2 (en) 2004-03-15 2017-04-28 Janssen Pharmaceutica Nv Opioid receptor modulators
EP2176234B1 (en) 2007-07-09 2016-01-27 Forest Tosara Limited Novel crystals and process of making 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy- benzoic acid
WO2017114446A1 (en) 2015-12-31 2017-07-06 苏州晶云药物科技有限公司 New crystal form of eluxadoline and preparation method thereof
WO2017191650A1 (en) 2016-05-03 2017-11-09 Msn Laboratories Private Limited Process for the preparation of 5-[[[(2s)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1s)-1-(4-phenyl-1h-imidazol-2-yl)ethyl]amino]methyl-2-methoxybenzoic acid and its polymorphs thereof
EP3272741A1 (en) 2016-07-21 2018-01-24 Euticals S.P.A. New stable solvate crystalline forms of eluxadoline
WO2018020450A2 (en) 2016-07-28 2018-02-01 Lupin Limited Process for the preparation of eluxadoline
WO2018047131A1 (en) 2016-09-09 2018-03-15 Sun Pharmaceutical Industries Limited Amorphous eluxadoline
WO2018138272A1 (en) 2017-01-27 2018-08-02 Quimica Sintetica, S. A. Eluxadoline crystalline form and process for the preparation thereof
EP3573958A1 (en) 2017-01-27 2019-12-04 Quimica Sintetica, S.A. Eluxadoline crystalline forms and processes for their preparation
WO2018185664A1 (en) 2017-04-03 2018-10-11 Sun Pharmaceutical Industries Limited Solvates of eluxadoline
WO2018185711A1 (en) 2017-04-05 2018-10-11 Sun Pharmaceutical Industries Limited Solvates of eluxadoline
WO2018198101A2 (en) 2017-04-25 2018-11-01 Sun Pharmaceutical Industries Limited Processes for the preparation of crystalline form of eluxadoline

Also Published As

Publication number Publication date
EP3325450A1 (en) 2018-05-30
US10314819B2 (en) 2019-06-11
US20180228773A1 (en) 2018-08-16
WO2017015606A1 (en) 2017-01-26

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