IL256000A - The quantification of the her 2 protein for optimal cancer treatment - Google Patents

The quantification of the her 2 protein for optimal cancer treatment

Info

Publication number
IL256000A
IL256000A IL256000A IL25600017A IL256000A IL 256000 A IL256000 A IL 256000A IL 256000 A IL256000 A IL 256000A IL 25600017 A IL25600017 A IL 25600017A IL 256000 A IL256000 A IL 256000A
Authority
IL
Israel
Prior art keywords
quantification
protein
cancer treatment
optimal cancer
optimal
Prior art date
Application number
IL256000A
Other languages
Hebrew (he)
Original Assignee
Expression Pathology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Expression Pathology Inc filed Critical Expression Pathology Inc
Publication of IL256000A publication Critical patent/IL256000A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • G01N33/5758
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
IL256000A 2015-05-29 2017-11-28 The quantification of the her 2 protein for optimal cancer treatment IL256000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562168709P 2015-05-29 2015-05-29
US201662310639P 2016-03-18 2016-03-18
PCT/US2016/035118 WO2016196523A1 (en) 2015-05-29 2016-05-31 Quantifying her2 protein for optimal cancer therapy

Publications (1)

Publication Number Publication Date
IL256000A true IL256000A (en) 2018-01-31

Family

ID=57397549

Family Applications (1)

Application Number Title Priority Date Filing Date
IL256000A IL256000A (en) 2015-05-29 2017-11-28 The quantification of the her 2 protein for optimal cancer treatment

Country Status (8)

Country Link
US (1) US10208130B2 (en)
EP (1) EP3304072A4 (en)
JP (1) JP6524266B2 (en)
KR (1) KR102067327B1 (en)
CN (1) CN108027360A (en)
AU (1) AU2016270686B2 (en)
IL (1) IL256000A (en)
WO (1) WO2016196523A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3144394B1 (en) 2010-12-08 2019-02-06 Expression Pathology, Inc. Truncated her2 srm/mrm assay
WO2017100663A1 (en) * 2015-12-09 2017-06-15 Expression Pathology, Inc. Improved methods for treating her2-positive breast cancer
EP3630095A1 (en) * 2017-06-02 2020-04-08 Expression Pathology, Inc. Predicting cancer treatment outcome with t-dm1
US20220221460A1 (en) 2019-03-08 2022-07-14 Seoul National University R&Db Foundation Method of quantifying her2 in breast cancer sample by mass spectrometry and scoring her2 status using the same
KR102462097B1 (en) * 2020-12-30 2022-11-02 국립암센터 Triple quadrupole-based multiple reaction monitoring for clinical therapeutic response prediction in cancer
CN115954046A (en) * 2022-12-02 2023-04-11 上海爱谱蒂康生物科技有限公司 Stomach cancer personalized treatment decision-making method and system and storage medium containing stomach cancer personalized treatment decision-making system
CN116819084A (en) * 2023-03-16 2023-09-29 天津云检医学检验所有限公司 Identification method and application of kit for identifying HER2 expression state of gastric cancer patient
CN116148482A (en) * 2023-04-20 2023-05-23 天津云检医学检验所有限公司 Device for identification of breast cancer patients and use for its preparation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473532B2 (en) 2003-03-10 2009-01-06 Expression Pathology, Inc. Liquid tissue preparation from histopathologically processed biological samples, tissues and cells
JO3000B1 (en) * 2004-10-20 2016-09-05 Genentech Inc Antibody Formulations.
ZA200704796B (en) * 2004-12-07 2008-11-26 Genentech Inc Selecting patients for therapy with a HER inhibitor
WO2008097229A1 (en) * 2007-02-09 2008-08-14 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Method for spectroscopic quantitation of her-2 in biological samples
EP2585488A2 (en) * 2010-06-24 2013-05-01 Modpro AB Novel biomarkers of liver cancer
EP3144394B1 (en) * 2010-12-08 2019-02-06 Expression Pathology, Inc. Truncated her2 srm/mrm assay
JP2012237586A (en) * 2011-05-10 2012-12-06 Fujirebio Inc Diagnostic reagent for selecting effective treatment method of anticancer agent
KR101992502B1 (en) * 2011-05-12 2019-06-24 제넨테크, 인크. Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides
AU2012267888A1 (en) * 2011-06-07 2014-01-30 Caris Mpi, Inc. Molecular profiling for cancer
ES3023516T3 (en) * 2011-10-14 2025-06-02 Hoffmann La Roche Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab
CN104302286A (en) * 2012-03-27 2015-01-21 英丘伦有限责任公司 CURAXINS for use in treating breast cancer and method for identifying patients likely to respond

Also Published As

Publication number Publication date
JP2018517906A (en) 2018-07-05
JP6524266B2 (en) 2019-06-05
KR20180036653A (en) 2018-04-09
AU2016270686A1 (en) 2018-01-25
CN108027360A (en) 2018-05-11
US10208130B2 (en) 2019-02-19
EP3304072A4 (en) 2018-12-05
WO2016196523A1 (en) 2016-12-08
EP3304072A1 (en) 2018-04-11
AU2016270686B2 (en) 2019-12-19
US20160349259A1 (en) 2016-12-01
KR102067327B1 (en) 2020-02-11

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