IL246676B - Administration of tasimelteon under fasted conditions - Google Patents
Administration of tasimelteon under fasted conditionsInfo
- Publication number
- IL246676B IL246676B IL246676A IL24667616A IL246676B IL 246676 B IL246676 B IL 246676B IL 246676 A IL246676 A IL 246676A IL 24667616 A IL24667616 A IL 24667616A IL 246676 B IL246676 B IL 246676B
- Authority
- IL
- Israel
- Prior art keywords
- administration
- fasted conditions
- under fasted
- tasimelteon
- tasimelteon under
- Prior art date
Links
- PTOIAAWZLUQTIO-GXFFZTMASA-N tasimelteon Chemical compound CCC(=O)NC[C@@H]1C[C@H]1C1=CC=CC2=C1CCO2 PTOIAAWZLUQTIO-GXFFZTMASA-N 0.000 title 1
- 229960000660 tasimelteon Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461927465P | 2014-01-14 | 2014-01-14 | |
| US14/511,669 US10376487B2 (en) | 2013-11-12 | 2014-10-10 | Method of treatment |
| PCT/US2015/010410 WO2015108728A1 (en) | 2014-01-14 | 2015-01-07 | Administration of tasimelteon under fasted conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL246676A0 IL246676A0 (en) | 2016-08-31 |
| IL246676B true IL246676B (en) | 2020-10-29 |
Family
ID=53520399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL246676A IL246676B (en) | 2014-01-14 | 2016-07-10 | Administration of tasimelteon under fasted conditions |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US10376487B2 (en) |
| EP (1) | EP3094322B1 (en) |
| JP (4) | JP2017502996A (en) |
| KR (3) | KR102276569B1 (en) |
| CN (2) | CN107072978A (en) |
| AU (3) | AU2015206797A1 (en) |
| CA (2) | CA3091827A1 (en) |
| CL (1) | CL2016001794A1 (en) |
| DK (1) | DK3094322T3 (en) |
| ES (1) | ES2805451T3 (en) |
| HR (1) | HRP20201069T1 (en) |
| HU (1) | HUE051244T2 (en) |
| IL (1) | IL246676B (en) |
| MX (1) | MX377438B (en) |
| NZ (1) | NZ722254A (en) |
| PT (1) | PT3094322T (en) |
| SI (1) | SI3094322T1 (en) |
| WO (1) | WO2015108728A1 (en) |
| ZA (1) | ZA201605103B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0712206A2 (en) * | 2006-05-22 | 2012-03-13 | Vanda Pharmaceuticals, Inc. | melatonin agonist treatment |
| US11918557B2 (en) | 2012-01-26 | 2024-03-05 | Vanda Pharmaceuticals Inc. | Treatment of circadian rhythm disorders |
| DK2806863T3 (en) | 2012-01-26 | 2017-10-30 | Vanda Pharmaceuticals Inc | Treatment of circadian rhythm disorders |
| US11090285B2 (en) | 2013-11-12 | 2021-08-17 | Vanda Pharmaceuticals Inc | Treatment of circadian rhythm disorders |
| US10376487B2 (en) | 2013-11-12 | 2019-08-13 | Vanda Pharmaceuticals Inc. | Method of treatment |
| BR112017003644A2 (en) * | 2014-09-02 | 2017-11-28 | Vanda Pharmaceuticals Inc | methods for treating sleep disorders and for regulating melatonin production. |
| US20210059973A1 (en) | 2017-08-02 | 2021-03-04 | Vanda Pharmaceuticals Inc. | Treatment of Affective Disorders |
| US20210353586A1 (en) * | 2018-09-12 | 2021-11-18 | Vanda Pharmaceuticals Inc. | Improving Sleep or Post-Sleep Performance |
| CN114727978A (en) | 2019-12-13 | 2022-07-08 | 万达制药公司 | Liquid tasimelteon formulations and methods of use thereof |
| EP4401723A1 (en) | 2021-09-14 | 2024-07-24 | Vanda Pharmaceuticals Inc. | Treatment of sleep disturbances in autism spectrum disorder patients |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL50699A0 (en) | 1975-10-28 | 1976-12-31 | Ici America Inc | Triazole derivatives |
| EP0126630B1 (en) | 1983-05-18 | 1987-09-16 | Monash University | The use of melatonin for the manufacture of a medicament |
| IL79264A0 (en) | 1986-06-27 | 1986-09-30 | Univ Ramot | Tryptamine derivatives,pharmaceutical compositions containing them and their use in an assay for melatonin receptors |
| US4997845A (en) | 1987-02-02 | 1991-03-05 | Eli Lilly And Company | β-alkylmelatonins as ovulation inhibitors |
| US5093352A (en) | 1988-11-14 | 1992-03-03 | Whitby Research, Inc. | Antidepressant agents |
| US5151446A (en) | 1989-09-25 | 1992-09-29 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
| FR2658818B1 (en) | 1990-02-27 | 1993-12-31 | Adir Cie | NOVEL DERIVATIVES WITH NAPHTHALENIC STRUCTURE, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US5242941A (en) | 1990-12-04 | 1993-09-07 | State Of Oregon | Methods of treating circadian rhythm disorders |
| US6638963B1 (en) | 1990-12-04 | 2003-10-28 | Oregon Health And Science University | Methods for treating circadian rhythm disorders |
| IT1251544B (en) | 1991-05-13 | 1995-05-17 | Gabriele Biella | PHARMACEUTICAL COMPOSITIONS ACTIVE IN THE THERAPY OF SLEEP DISORDERS INCLUDING MELATONIN OR A DERIVATIVE IN ASSOCIATION WITH A BENZODIAZEPINE DERIVATIVE |
| US6180657B1 (en) | 1993-11-18 | 2001-01-30 | Eli Lilly And Company | Melatonin derivatives for use in treating desynchronization disorders |
| US5403851A (en) | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
| GB9416884D0 (en) | 1994-08-20 | 1994-10-12 | Danbiosyst Uk | Drug delivery compositions |
| AT408188B (en) | 1995-02-01 | 2001-09-25 | Neurim Pharma 1991 | USE OF MELATONIN FOR THE TREATMENT OF PATIENTS SUGGESTED IN DRUG ADDICTION |
| US5932541A (en) | 1995-10-24 | 1999-08-03 | Gruenenthal Gmbh | Method of adjusting the circadian rhythm of a mammal |
| EP1027043B1 (en) | 1996-12-10 | 2004-11-10 | Bristol-Myers Squibb Company | Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agents |
| US5776969A (en) | 1997-02-27 | 1998-07-07 | Eli Lilly And Company | Treatment of sleep disorders |
| AUPO588297A0 (en) | 1997-03-26 | 1997-04-24 | Luminis Pty Limited | Mediation in melatonin production |
| KR100642024B1 (en) | 1998-06-09 | 2006-11-06 | 다케다 야쿠힌 고교 가부시키가이샤 | Pharmaceutical compositions for treating or preventing sleep disorders |
| US6562858B2 (en) | 1999-05-17 | 2003-05-13 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating depression |
| ATE257834T1 (en) | 1999-06-30 | 2004-01-15 | Bristol Myers Squibb Co | HETEROCYCLIC AMINOPYRROLIDONE DERIVATIVES AS MELATONERGENIC ACTIVES |
| EP1441727B1 (en) | 2001-10-30 | 2010-12-29 | Novartis AG | Depot formulations of iloperidone and a star polymer |
| GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
| IL155666A (en) | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Composition for treating insomnia |
| JP2005080603A (en) | 2003-09-10 | 2005-03-31 | Kumamoto Technology & Industry Foundation | How to determine the degree of biological rhythm disorder |
| US20050137247A1 (en) | 2003-12-22 | 2005-06-23 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treatment of hypertension |
| AU2004308962A1 (en) | 2003-12-24 | 2005-07-14 | Sepracor Inc. | Melatonin combination therapy for improving sleep quality |
| WO2007016203A1 (en) | 2005-07-29 | 2007-02-08 | Vanda Pharmaceuticals, Inc. | Method of improving wakefulness |
| US7754902B2 (en) | 2006-05-18 | 2010-07-13 | Vanda Pharmaceuticals, Inc. | Ruthenium(II) catalysts for use in stereoselective cyclopropanations |
| BRPI0712206A2 (en) | 2006-05-22 | 2012-03-13 | Vanda Pharmaceuticals, Inc. | melatonin agonist treatment |
| CA2652421A1 (en) | 2006-05-22 | 2007-11-29 | Vanda Pharmaceuticals, Inc. | Treatment for depressive disorders |
| CA2693992C (en) | 2006-07-20 | 2017-01-31 | Somaxon Pharmaceuticals, Inc. | Methods of improving the pharmacokinetics of doxepin |
| BRPI0714714A2 (en) | 2006-07-21 | 2013-04-09 | Univ California | compositions of human endogenous retrovirus polypeptide and (herv) and their methods and uses |
| US20110077200A1 (en) | 2006-12-06 | 2011-03-31 | Somaxon Pharmaceuticals, Inc. | Combination therapy using low-dose doxepin for the improvement of sleep |
| PL2139485T3 (en) | 2007-04-11 | 2013-03-29 | Biomarin Pharm Inc | Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring |
| US11060144B2 (en) | 2007-09-13 | 2021-07-13 | Vanda Pharmaceuticals Inc. | Prediction of sleep parameter and response to sleep-inducing compound based on PER3 VNTR genotype |
| WO2009084023A2 (en) | 2007-10-19 | 2009-07-09 | Glenmark Generics Limited | Amorphous ramelteon and process for the preparation thereof |
| WO2009058261A1 (en) | 2007-10-31 | 2009-05-07 | Merck & Co., Inc. | Modulation of sleep with nr2b receptor antagonists |
| JP5558016B2 (en) | 2009-03-17 | 2014-07-23 | 株式会社 資生堂 | Circadian rhythm regulator |
| NZ602010A (en) | 2009-04-07 | 2013-11-29 | Duocort Pharma Ab | Improved glucocorticoid therapy |
| EP2453891A1 (en) | 2009-07-16 | 2012-05-23 | Vanda Pharmaceuticals Inc. | Use of a melatonin agonist for the treatment of sleep disorders including primary insomnia |
| DK2806863T3 (en) | 2012-01-26 | 2017-10-30 | Vanda Pharmaceuticals Inc | Treatment of circadian rhythm disorders |
| US10376487B2 (en) | 2013-11-12 | 2019-08-13 | Vanda Pharmaceuticals Inc. | Method of treatment |
| EP4223747A1 (en) | 2014-02-12 | 2023-08-09 | Vanda Pharmaceuticals Inc. | Highly purified pharmaceutical grade tasimelteon |
-
2014
- 2014-10-10 US US14/511,669 patent/US10376487B2/en active Active
-
2015
- 2015-01-07 EP EP15701861.5A patent/EP3094322B1/en active Active
- 2015-01-07 HU HUE15701861A patent/HUE051244T2/en unknown
- 2015-01-07 JP JP2016546950A patent/JP2017502996A/en active Pending
- 2015-01-07 KR KR1020207025212A patent/KR102276569B1/en active Active
- 2015-01-07 KR KR1020167021922A patent/KR101970050B1/en active Active
- 2015-01-07 DK DK15701861.5T patent/DK3094322T3/en active
- 2015-01-07 PT PT157018615T patent/PT3094322T/en unknown
- 2015-01-07 CA CA3091827A patent/CA3091827A1/en not_active Abandoned
- 2015-01-07 MX MX2016009231A patent/MX377438B/en active IP Right Grant
- 2015-01-07 CA CA2936504A patent/CA2936504C/en active Active
- 2015-01-07 SI SI201531280T patent/SI3094322T1/en unknown
- 2015-01-07 HR HRP20201069TT patent/HRP20201069T1/en unknown
- 2015-01-07 KR KR1020197010189A patent/KR102154458B1/en active Active
- 2015-01-07 CN CN201580004542.9A patent/CN107072978A/en active Pending
- 2015-01-07 ES ES15701861T patent/ES2805451T3/en active Active
- 2015-01-07 CN CN202211546550.4A patent/CN116115551A/en active Pending
- 2015-01-07 WO PCT/US2015/010410 patent/WO2015108728A1/en not_active Ceased
- 2015-01-07 NZ NZ722254A patent/NZ722254A/en unknown
- 2015-01-07 AU AU2015206797A patent/AU2015206797A1/en not_active Abandoned
-
2016
- 2016-07-10 IL IL246676A patent/IL246676B/en active IP Right Grant
- 2016-07-13 CL CL2016001794A patent/CL2016001794A1/en unknown
- 2016-07-21 ZA ZA2016/05103A patent/ZA201605103B/en unknown
-
2019
- 2019-07-19 US US16/517,111 patent/US10610511B2/en active Active
-
2020
- 2020-02-25 US US16/800,611 patent/US11141400B2/en active Active
- 2020-04-23 AU AU2020202719A patent/AU2020202719B2/en active Active
-
2021
- 2021-03-22 JP JP2021047935A patent/JP2021102634A/en active Pending
- 2021-08-20 US US17/407,921 patent/US11786502B2/en active Active
-
2022
- 2022-03-21 AU AU2022201953A patent/AU2022201953A1/en not_active Abandoned
- 2022-12-23 JP JP2022206745A patent/JP2023024704A/en active Pending
-
2025
- 2025-07-24 JP JP2025124086A patent/JP2025137763A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |