IL237300B - Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine - Google Patents

Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine

Info

Publication number
IL237300B
IL237300B IL237300A IL23730015A IL237300B IL 237300 B IL237300 B IL 237300B IL 237300 A IL237300 A IL 237300A IL 23730015 A IL23730015 A IL 23730015A IL 237300 B IL237300 B IL 237300B
Authority
IL
Israel
Prior art keywords
gemicitabine
treatment
methods
drug delivery
delivery systems
Prior art date
Application number
IL237300A
Other languages
Hebrew (he)
Other versions
IL237300A0 (en
Original Assignee
Taris Biomedical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taris Biomedical Llc filed Critical Taris Biomedical Llc
Publication of IL237300A0 publication Critical patent/IL237300A0/en
Publication of IL237300B publication Critical patent/IL237300B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1078Urinary tract
    • A61M2210/1085Bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/16Male reproductive, genital organs
    • A61M2210/166Prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nanotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
IL237300A 2012-08-31 2015-02-18 Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine IL237300B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261696029P 2012-08-31 2012-08-31
PCT/US2013/057841 WO2014036556A2 (en) 2012-08-31 2013-09-03 Drug delivery systems and methods for treatment of prostate

Publications (2)

Publication Number Publication Date
IL237300A0 IL237300A0 (en) 2015-04-30
IL237300B true IL237300B (en) 2020-02-27

Family

ID=49162284

Family Applications (1)

Application Number Title Priority Date Filing Date
IL237300A IL237300B (en) 2012-08-31 2015-02-18 Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine

Country Status (14)

Country Link
US (2) US9636488B2 (en)
EP (1) EP2890386A2 (en)
JP (1) JP6309009B2 (en)
KR (2) KR20150043508A (en)
CN (2) CN112516154A (en)
AU (1) AU2013308465B2 (en)
BR (1) BR112015004110A2 (en)
CA (1) CA2882575C (en)
IL (1) IL237300B (en)
IN (1) IN2015DN01560A (en)
MX (1) MX367070B (en)
RU (1) RU2678308C2 (en)
SG (1) SG11201501483XA (en)
WO (1) WO2014036556A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015004110A2 (en) 2012-08-31 2017-07-04 Taris Biomedical Llc prostate drug delivery systems and methods
RU2657591C2 (en) 2012-08-31 2018-06-14 ТАРИС Биомедикал ЛЛК Method for treatment of bladder cancer with oxaliplatin, corresponding delivery device, method and device for administration thereof
LT3035991T (en) 2013-08-19 2020-11-10 Taris Biomedical Llc Multi-unit drug delivery devices
PT4124339T (en) * 2014-03-06 2025-11-04 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine
US10675289B2 (en) * 2014-10-02 2020-06-09 University Of Maryland, Baltimore Methods of treating pancreatic cancer
RU2022100624A (en) 2016-05-06 2022-02-09 ТЭРИС БАЙОМЕДИКАЛ ЭлЭлСи METHOD FOR THE TREATMENT OF CANCER OF THE LOWER TRACT UROTHELIA
SG10201913998YA (en) * 2017-07-25 2020-03-30 Taris Biomedical Llc Methods of treating tumor metastasis
CA3081839A1 (en) 2017-11-08 2019-05-16 Taris Biomedical Llc Methods of treatment and maintenance therapy for bladder cancer using gemcitabine
MX2021001264A (en) 2018-08-01 2021-07-02 Taris Biomedical Llc Methods of treating overactive bladder using trospium.
US20220107320A1 (en) 2019-02-15 2022-04-07 Incelldx, Inc. Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171298B1 (en) 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
AU2003301669B2 (en) 2002-10-22 2009-04-30 Biomerix Corporation Method and system for intravesicular delivery of the therapeutic agents
US8361490B2 (en) 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
DE102005020314A1 (en) * 2005-05-02 2006-11-09 Infineon Technologies Ag A power supply arrangement for supplying a first electrical load and method for providing an electrical power
CA2618349C (en) 2005-08-11 2016-05-31 Massachusetts Institute Of Technology Intravesical drug delivery device and method
EP2049139A4 (en) 2006-04-24 2009-06-24 Gloucester Pharmaceuticals Inc Treatment of ras-expressing tumors
EP1913962A1 (en) * 2006-10-22 2008-04-23 Ophir Perelson Expandable medical device for the treatment and prevention of cardiovascular diseases
EP2116246A1 (en) * 2007-01-19 2009-11-11 Eisai R&D Management Co., Ltd. Composition for treatment of pancreatic cancer
JP5560200B2 (en) 2007-12-11 2014-07-23 マサチューセッツ インスチテュート オブ テクノロジー Implantable drug delivery device for treating bladder and other body vesicles or lumens
CN102065841A (en) 2008-04-04 2011-05-18 里培拉药品公司 Treatment of bladder dysfunction using liposomal botulinum toxin
CA2730995C (en) * 2008-07-17 2016-11-22 Micell Technologies, Inc. Drug delivery medical device
KR101794899B1 (en) 2008-08-09 2017-11-07 메사츄세츠 인스티튜트 어브 테크놀로지 Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues
AU2010265863C1 (en) 2009-06-26 2012-11-01 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
DK3884988T3 (en) 2009-12-17 2025-08-18 Taris Biomedical Llc IMPLANTABLE DEVICE WITH INTRAVESICAL TOLERABILITY
ES2732150T3 (en) 2010-01-20 2019-11-20 Urogen Pharma Ltd Material and method to treat internal cavities
US20110218488A1 (en) 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
EP3741330A3 (en) 2010-08-05 2020-12-30 TARIS Biomedical LLC Ureteral stent drug delivery device
WO2012048104A1 (en) 2010-10-06 2012-04-12 Taris Biomedical, Inc. Implantable drug delivery device with bladden retention feature
JP5945544B2 (en) 2010-10-06 2016-07-05 タリス バイオメディカル エルエルシー Time-selective bioabsorbable or disintegratable drug delivery system and method
US8979797B2 (en) 2010-12-16 2015-03-17 Ams Research Corporation High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics
US9114111B2 (en) 2011-01-10 2015-08-25 Allergan, Inc. Methods for sustained treatment of bladder pain and irritative voiding
JP6043730B2 (en) * 2011-02-04 2016-12-14 タリス バイオメディカル エルエルシー Implantable device for controlled release of low solubility drugs
US20150005595A1 (en) 2011-12-30 2015-01-01 Kibur Medical, Inc. Implantable devices and methods for evaluation of active agents
WO2013170069A1 (en) 2012-05-09 2013-11-14 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
RU2657591C2 (en) 2012-08-31 2018-06-14 ТАРИС Биомедикал ЛЛК Method for treatment of bladder cancer with oxaliplatin, corresponding delivery device, method and device for administration thereof
BR112015004110A2 (en) 2012-08-31 2017-07-04 Taris Biomedical Llc prostate drug delivery systems and methods
JP6600256B2 (en) 2012-09-18 2019-10-30 タリス バイオメディカル エルエルシー Drug delivery system and method for the treatment of bladder dysfunction and other lower urinary tract diseases through the use of trospium
US9814671B2 (en) 2013-03-15 2017-11-14 Taris Biomedical Llc Drug delivery devices and methods for drug delivery
DK2968880T3 (en) 2013-03-15 2025-05-19 Taris Biomedical Llc DRUG DELIVERY DEVICES WITH DRUG PERMEABLE COMPONENT
CA2944480C (en) 2013-04-10 2021-05-18 Massachusetts Institute Of Technology Local drug delivery devices and methods for treating cancer
LT3035991T (en) 2013-08-19 2020-11-10 Taris Biomedical Llc Multi-unit drug delivery devices
PT4124339T (en) 2014-03-06 2025-11-04 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine

Also Published As

Publication number Publication date
CN104812395A (en) 2015-07-29
KR20150043508A (en) 2015-04-22
SG11201501483XA (en) 2015-03-30
IL237300A0 (en) 2015-04-30
AU2013308465A1 (en) 2015-03-05
KR102383496B1 (en) 2022-04-08
JP6309009B2 (en) 2018-04-11
MX367070B (en) 2019-08-05
KR20200120774A (en) 2020-10-21
CA2882575A1 (en) 2014-03-06
US20150165177A1 (en) 2015-06-18
WO2014036556A3 (en) 2014-04-17
RU2678308C2 (en) 2019-01-25
CA2882575C (en) 2020-05-26
BR112015004110A2 (en) 2017-07-04
EP2890386A2 (en) 2015-07-08
US20170203085A1 (en) 2017-07-20
IN2015DN01560A (en) 2015-07-03
US9636488B2 (en) 2017-05-02
AU2013308465B2 (en) 2018-05-17
RU2015109298A (en) 2016-10-20
JP2015528469A (en) 2015-09-28
US10406335B2 (en) 2019-09-10
WO2014036556A2 (en) 2014-03-06
CN112516154A (en) 2021-03-19
MX2015002452A (en) 2015-06-05

Similar Documents

Publication Publication Date Title
IL237300B (en) Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine
IL239557A0 (en) Microarray for delivery of therapeutic agent and methods of use
ZA201506984B (en) Microarray for delivery of therapeutic agent and methods of use
IL238638A0 (en) Dosing and administration of oligonucleotide cancer terapies
SG11201500937UA (en) Extrusion methods and devices for drug delivery
SG2014012488A (en) Multiple drug infusion system and method
EP2890440A4 (en) Devices and methods for the treatment of vascular disease
SG10201800720YA (en) Blood treatment systems and methods
ZA201405898B (en) Devices for targeted delivery of therapeutic implants
EP2720748A4 (en) Transdermal drug delivery system and method of using the same
EP2782631A4 (en) Implantable solid-liquig drug delivery apparatus, formulations, and methods of use
IL229407A0 (en) Medicament delivery device and method of controlling the device
IL240849A0 (en) Drug delivery devices and methods for drug delivery
EP2908874A4 (en) Drug delivery medical device
EP2776115A4 (en) Medicinal patch and injector system
GB201319681D0 (en) System and method for drug delivery
SG11201403756PA (en) Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
IL237281B (en) Drug delivery systems and methods for treatment of bladder cancer comprising oxaliplatin
ZA201206117B (en) Therapeutic delivery devices, systems, and methods
IL230998A0 (en) Drug delivery system and method of manufacturing thereof
EP2755686A4 (en) Methods and systems for making microtablets for drug delivery
IL254182B (en) Drug delivery system and method of manufacturing thereof
EP2763716A4 (en) Solid drug delivery apparatus, formulations and methods of use
IL232390A0 (en) Device for pressure enhanced fractional treatment and drug delivery
IL230999A0 (en) Drug delivery system and method of manufacturing thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed