IL237300B - Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine - Google Patents
Drug delivery systems and methods for treatment of prostate disease comprising gemicitabineInfo
- Publication number
- IL237300B IL237300B IL237300A IL23730015A IL237300B IL 237300 B IL237300 B IL 237300B IL 237300 A IL237300 A IL 237300A IL 23730015 A IL23730015 A IL 23730015A IL 237300 B IL237300 B IL 237300B
- Authority
- IL
- Israel
- Prior art keywords
- gemicitabine
- treatment
- methods
- drug delivery
- delivery systems
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 208000017497 prostate disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/04—General characteristics of the apparatus implanted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1078—Urinary tract
- A61M2210/1085—Bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/16—Male reproductive, genital organs
- A61M2210/166—Prostate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nanotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261696029P | 2012-08-31 | 2012-08-31 | |
| PCT/US2013/057841 WO2014036556A2 (en) | 2012-08-31 | 2013-09-03 | Drug delivery systems and methods for treatment of prostate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL237300A0 IL237300A0 (en) | 2015-04-30 |
| IL237300B true IL237300B (en) | 2020-02-27 |
Family
ID=49162284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL237300A IL237300B (en) | 2012-08-31 | 2015-02-18 | Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9636488B2 (en) |
| EP (1) | EP2890386A2 (en) |
| JP (1) | JP6309009B2 (en) |
| KR (2) | KR20150043508A (en) |
| CN (2) | CN112516154A (en) |
| AU (1) | AU2013308465B2 (en) |
| BR (1) | BR112015004110A2 (en) |
| CA (1) | CA2882575C (en) |
| IL (1) | IL237300B (en) |
| IN (1) | IN2015DN01560A (en) |
| MX (1) | MX367070B (en) |
| RU (1) | RU2678308C2 (en) |
| SG (1) | SG11201501483XA (en) |
| WO (1) | WO2014036556A2 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015004110A2 (en) | 2012-08-31 | 2017-07-04 | Taris Biomedical Llc | prostate drug delivery systems and methods |
| RU2657591C2 (en) | 2012-08-31 | 2018-06-14 | ТАРИС Биомедикал ЛЛК | Method for treatment of bladder cancer with oxaliplatin, corresponding delivery device, method and device for administration thereof |
| LT3035991T (en) | 2013-08-19 | 2020-11-10 | Taris Biomedical Llc | Multi-unit drug delivery devices |
| PT4124339T (en) * | 2014-03-06 | 2025-11-04 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
| US10675289B2 (en) * | 2014-10-02 | 2020-06-09 | University Of Maryland, Baltimore | Methods of treating pancreatic cancer |
| RU2022100624A (en) | 2016-05-06 | 2022-02-09 | ТЭРИС БАЙОМЕДИКАЛ ЭлЭлСи | METHOD FOR THE TREATMENT OF CANCER OF THE LOWER TRACT UROTHELIA |
| SG10201913998YA (en) * | 2017-07-25 | 2020-03-30 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| CA3081839A1 (en) | 2017-11-08 | 2019-05-16 | Taris Biomedical Llc | Methods of treatment and maintenance therapy for bladder cancer using gemcitabine |
| MX2021001264A (en) | 2018-08-01 | 2021-07-02 | Taris Biomedical Llc | Methods of treating overactive bladder using trospium. |
| US20220107320A1 (en) | 2019-02-15 | 2022-04-07 | Incelldx, Inc. | Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6171298B1 (en) | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
| AU2003301669B2 (en) | 2002-10-22 | 2009-04-30 | Biomerix Corporation | Method and system for intravesicular delivery of the therapeutic agents |
| US8361490B2 (en) | 2004-09-16 | 2013-01-29 | Theracoat Ltd. | Biocompatible drug delivery apparatus and methods |
| DE102005020314A1 (en) * | 2005-05-02 | 2006-11-09 | Infineon Technologies Ag | A power supply arrangement for supplying a first electrical load and method for providing an electrical power |
| CA2618349C (en) | 2005-08-11 | 2016-05-31 | Massachusetts Institute Of Technology | Intravesical drug delivery device and method |
| EP2049139A4 (en) | 2006-04-24 | 2009-06-24 | Gloucester Pharmaceuticals Inc | Treatment of ras-expressing tumors |
| EP1913962A1 (en) * | 2006-10-22 | 2008-04-23 | Ophir Perelson | Expandable medical device for the treatment and prevention of cardiovascular diseases |
| EP2116246A1 (en) * | 2007-01-19 | 2009-11-11 | Eisai R&D Management Co., Ltd. | Composition for treatment of pancreatic cancer |
| JP5560200B2 (en) | 2007-12-11 | 2014-07-23 | マサチューセッツ インスチテュート オブ テクノロジー | Implantable drug delivery device for treating bladder and other body vesicles or lumens |
| CN102065841A (en) | 2008-04-04 | 2011-05-18 | 里培拉药品公司 | Treatment of bladder dysfunction using liposomal botulinum toxin |
| CA2730995C (en) * | 2008-07-17 | 2016-11-22 | Micell Technologies, Inc. | Drug delivery medical device |
| KR101794899B1 (en) | 2008-08-09 | 2017-11-07 | 메사츄세츠 인스티튜트 어브 테크놀로지 | Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues |
| AU2010265863C1 (en) | 2009-06-26 | 2012-11-01 | Taris Biomedical Llc | Implantable drug delivery devices and methods of making the same |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| DK3884988T3 (en) | 2009-12-17 | 2025-08-18 | Taris Biomedical Llc | IMPLANTABLE DEVICE WITH INTRAVESICAL TOLERABILITY |
| ES2732150T3 (en) | 2010-01-20 | 2019-11-20 | Urogen Pharma Ltd | Material and method to treat internal cavities |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| EP3741330A3 (en) | 2010-08-05 | 2020-12-30 | TARIS Biomedical LLC | Ureteral stent drug delivery device |
| WO2012048104A1 (en) | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Implantable drug delivery device with bladden retention feature |
| JP5945544B2 (en) | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | Time-selective bioabsorbable or disintegratable drug delivery system and method |
| US8979797B2 (en) | 2010-12-16 | 2015-03-17 | Ams Research Corporation | High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics |
| US9114111B2 (en) | 2011-01-10 | 2015-08-25 | Allergan, Inc. | Methods for sustained treatment of bladder pain and irritative voiding |
| JP6043730B2 (en) * | 2011-02-04 | 2016-12-14 | タリス バイオメディカル エルエルシー | Implantable device for controlled release of low solubility drugs |
| US20150005595A1 (en) | 2011-12-30 | 2015-01-01 | Kibur Medical, Inc. | Implantable devices and methods for evaluation of active agents |
| WO2013170069A1 (en) | 2012-05-09 | 2013-11-14 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
| RU2657591C2 (en) | 2012-08-31 | 2018-06-14 | ТАРИС Биомедикал ЛЛК | Method for treatment of bladder cancer with oxaliplatin, corresponding delivery device, method and device for administration thereof |
| BR112015004110A2 (en) | 2012-08-31 | 2017-07-04 | Taris Biomedical Llc | prostate drug delivery systems and methods |
| JP6600256B2 (en) | 2012-09-18 | 2019-10-30 | タリス バイオメディカル エルエルシー | Drug delivery system and method for the treatment of bladder dysfunction and other lower urinary tract diseases through the use of trospium |
| US9814671B2 (en) | 2013-03-15 | 2017-11-14 | Taris Biomedical Llc | Drug delivery devices and methods for drug delivery |
| DK2968880T3 (en) | 2013-03-15 | 2025-05-19 | Taris Biomedical Llc | DRUG DELIVERY DEVICES WITH DRUG PERMEABLE COMPONENT |
| CA2944480C (en) | 2013-04-10 | 2021-05-18 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
| LT3035991T (en) | 2013-08-19 | 2020-11-10 | Taris Biomedical Llc | Multi-unit drug delivery devices |
| PT4124339T (en) | 2014-03-06 | 2025-11-04 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
-
2013
- 2013-09-03 BR BR112015004110A patent/BR112015004110A2/en not_active Application Discontinuation
- 2013-09-03 MX MX2015002452A patent/MX367070B/en active IP Right Grant
- 2013-09-03 AU AU2013308465A patent/AU2013308465B2/en not_active Ceased
- 2013-09-03 KR KR20157007350A patent/KR20150043508A/en not_active Ceased
- 2013-09-03 CN CN202011468367.8A patent/CN112516154A/en active Pending
- 2013-09-03 EP EP13760226.4A patent/EP2890386A2/en not_active Withdrawn
- 2013-09-03 CA CA2882575A patent/CA2882575C/en active Active
- 2013-09-03 KR KR1020207029566A patent/KR102383496B1/en not_active Expired - Fee Related
- 2013-09-03 WO PCT/US2013/057841 patent/WO2014036556A2/en not_active Ceased
- 2013-09-03 SG SG11201501483XA patent/SG11201501483XA/en unknown
- 2013-09-03 JP JP2015530139A patent/JP6309009B2/en not_active Expired - Fee Related
- 2013-09-03 CN CN201380044809.8A patent/CN104812395A/en active Pending
- 2013-09-03 RU RU2015109298A patent/RU2678308C2/en active
-
2015
- 2015-02-18 IL IL237300A patent/IL237300B/en active IP Right Grant
- 2015-02-23 US US14/628,874 patent/US9636488B2/en not_active Expired - Fee Related
- 2015-02-25 IN IN1560DEN2015 patent/IN2015DN01560A/en unknown
-
2017
- 2017-03-29 US US15/473,437 patent/US10406335B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104812395A (en) | 2015-07-29 |
| KR20150043508A (en) | 2015-04-22 |
| SG11201501483XA (en) | 2015-03-30 |
| IL237300A0 (en) | 2015-04-30 |
| AU2013308465A1 (en) | 2015-03-05 |
| KR102383496B1 (en) | 2022-04-08 |
| JP6309009B2 (en) | 2018-04-11 |
| MX367070B (en) | 2019-08-05 |
| KR20200120774A (en) | 2020-10-21 |
| CA2882575A1 (en) | 2014-03-06 |
| US20150165177A1 (en) | 2015-06-18 |
| WO2014036556A3 (en) | 2014-04-17 |
| RU2678308C2 (en) | 2019-01-25 |
| CA2882575C (en) | 2020-05-26 |
| BR112015004110A2 (en) | 2017-07-04 |
| EP2890386A2 (en) | 2015-07-08 |
| US20170203085A1 (en) | 2017-07-20 |
| IN2015DN01560A (en) | 2015-07-03 |
| US9636488B2 (en) | 2017-05-02 |
| AU2013308465B2 (en) | 2018-05-17 |
| RU2015109298A (en) | 2016-10-20 |
| JP2015528469A (en) | 2015-09-28 |
| US10406335B2 (en) | 2019-09-10 |
| WO2014036556A2 (en) | 2014-03-06 |
| CN112516154A (en) | 2021-03-19 |
| MX2015002452A (en) | 2015-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |