IL227868D0 - Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient - Google Patents

Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

Info

Publication number
IL227868D0
IL227868D0 IL227868A IL22786813A IL227868D0 IL 227868 D0 IL227868 D0 IL 227868D0 IL 227868 A IL227868 A IL 227868A IL 22786813 A IL22786813 A IL 22786813A IL 227868 D0 IL227868 D0 IL 227868D0
Authority
IL
Israel
Prior art keywords
patient
nerve
interface element
neck
non
Prior art date
Application number
IL227868A
Other languages
Hebrew (he)
Other versions
IL227868A (en
Original Assignee
Electrocore Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201161451259P priority Critical
Priority to US13/075,746 priority patent/US8874205B2/en
Priority to US201161488208P priority
Priority to US13/183,765 priority patent/US8874227B2/en
Priority to PCT/US2011/049844 priority patent/WO2012121750A1/en
Application filed by Electrocore Llc filed Critical Electrocore Llc
Publication of IL227868D0 publication Critical patent/IL227868D0/en
Publication of IL227868A publication Critical patent/IL227868A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • A61N1/0496Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0072Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation

Abstract

A non-invasive electrical stimulator shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in contact with the electrodes. The conducting medium is also in contact with an interface element that may conform to the contour of a target body surface of the patient when the interface element is applied to that surface. When the interface element is made of insulating (dielectric) material, and disclosed stimulation waveforms are used, the power source need not supply high voltage, in order to capacitively stimulate the target nerve. The stimulator is configured to produce a peak pulse that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie in the vicinity of the target nerve and patient's skin.
IL227868A 2009-03-20 2013-08-08 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient IL227868A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US201161451259P true 2011-03-10 2011-03-10
US13/075,746 US8874205B2 (en) 2009-03-20 2011-03-30 Device and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation
US201161488208P true 2011-05-20 2011-05-20
US13/183,765 US8874227B2 (en) 2009-03-20 2011-07-15 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
PCT/US2011/049844 WO2012121750A1 (en) 2011-03-10 2011-08-31 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

Publications (2)

Publication Number Publication Date
IL227868D0 true IL227868D0 (en) 2013-09-30
IL227868A IL227868A (en) 2019-02-28

Family

ID=46798501

Family Applications (1)

Application Number Title Priority Date Filing Date
IL227868A IL227868A (en) 2009-03-20 2013-08-08 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

Country Status (9)

Country Link
US (4) US8874227B2 (en)
EP (3) EP2962725A1 (en)
JP (2) JP2014510586A (en)
CN (1) CN103517732B (en)
AU (2) AU2011361696B2 (en)
CA (1) CA2826835C (en)
IL (1) IL227868A (en)
MX (1) MX351494B (en)
WO (1) WO2012121750A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US8660647B2 (en) * 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US9403001B2 (en) * 2009-03-20 2016-08-02 ElectroCore, LLC Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
US9119953B2 (en) * 2005-11-10 2015-09-01 ElectroCore, LLC Non-invasive treatment of a medical condition by vagus nerve stimulation
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
CN102014779B (en) 2008-05-09 2014-10-22 赫莱拉公司 A system, components and methods for treating bronchial tree
CA2779135C (en) 2009-10-27 2018-09-04 Innovative Pulmonary Solutions, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
AU2010319477A1 (en) 2009-11-11 2012-05-24 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
WO2015179744A1 (en) * 2014-05-23 2015-11-26 ElectroCore, LLC Systems and methods for vagal nerve stimulation
US9764133B2 (en) 2012-01-13 2017-09-19 Modular Therapeutx, Llc Portable TENS apparatus and method of use thereof
AU2013207901B2 (en) * 2012-01-13 2015-08-20 Modular Therapeutx, Llc Portable TENS apparatus and method of use thereof
US8972016B2 (en) 2012-01-13 2015-03-03 Modular Therapeutx, Llc Portable TENS apparatus and method of use thereof
EP2830492A4 (en) * 2012-03-30 2015-11-18 Univ Illinois Appendage mountable electronic devices conformable to surfaces
US9440070B2 (en) 2012-11-26 2016-09-13 Thyne Global, Inc. Wearable transdermal electrical stimulation devices and methods of using them
WO2014082064A1 (en) 2012-11-26 2014-05-30 Thync, Inc. Wearable transdermal electrical stimulation devices and methods of using them
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
WO2015179571A1 (en) * 2014-05-20 2015-11-26 ElectroCore, LLC Non-invasive nerve stimulation via mobile devices
BR112015017042A2 (en) 2013-01-21 2017-07-11 Cala Health Inc devices and methods for controlling tremor
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
WO2014139685A1 (en) * 2013-03-15 2014-09-18 Nes Health, Ltd. Pulse polarity switching for improved human body stimulation and healing
US9242085B2 (en) 2013-06-28 2016-01-26 Boston Scientific Neuromodulation Corporation Transcutaneous electrical stimulation for treating neurological disorders
WO2014210595A1 (en) 2013-06-29 2014-12-31 Thync, Inc. Transdermal electrical stimulation devices and methods for modifying or inducing cognitive state
US10293161B2 (en) 2013-06-29 2019-05-21 Thync Global, Inc. Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
US9956405B2 (en) 2015-12-18 2018-05-01 Thyne Global, Inc. Transdermal electrical stimulation at the neck to induce neuromodulation
EP3038700A4 (en) 2013-08-27 2017-04-26 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
EP3038699A4 (en) * 2013-08-27 2017-03-29 Halo Neuro, Inc. Electrode system for electrical stimulation
US9486618B2 (en) 2013-08-27 2016-11-08 Halo Neuro, Inc. Electrode system for electrical stimulation
US9782585B2 (en) 2013-08-27 2017-10-10 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
WO2015131093A1 (en) 2014-02-27 2015-09-03 Thync, Inc. Methods and apparatuses for user control of neurostimulation
WO2015179281A2 (en) 2014-05-17 2015-11-26 Thync, Inc. Methods and apparatuses for the application of ensemble waveforms using transdermal neurostimulation
WO2015183620A2 (en) 2014-05-25 2015-12-03 Thync, Inc. Wearable transdermal neurostimulators
US9333334B2 (en) 2014-05-25 2016-05-10 Thync, Inc. Methods for attaching and wearing a neurostimulator
CN106413805A (en) 2014-06-02 2017-02-15 卡拉健康公司 Systems and methods for peripheral nerve stimulation to treat tremor
US10258788B2 (en) 2015-01-05 2019-04-16 Thync Global, Inc. Electrodes having surface exclusions
WO2016113661A1 (en) 2015-01-13 2016-07-21 Siano Mobile Silicon Ltd. Treatment of headaches by electrical stimulation
EP3413966A1 (en) 2016-02-08 2018-12-19 Halo Neuro, Inc. Method and system for improving provision of electrical stimulation
RU186964U1 (en) * 2018-04-17 2019-02-11 Артем Олегович Кузнецов Apparatus non-surgical recovery of locomotor function paralyzed parts of the body and the stimulation of damaged nerve endings

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR446660A (en) 1911-09-02 1912-12-12 Gottlieb Schuettel Device for continuous weaving rings for mounting the sliders on the rings
US3077884A (en) 1957-06-13 1963-02-19 Batrow Lab Inc Electro-physiotherapy apparatus
US3279468A (en) 1963-05-14 1966-10-18 Vine Sidney Le Electrotherapeutic facial mask apparatus
US3568662A (en) 1967-07-07 1971-03-09 Donald B Everett Method and apparatus for sensing bioelectric potentials
US3590810A (en) 1968-05-27 1971-07-06 Honeywell Inc Biomedical body electrode
US3659614A (en) 1969-12-29 1972-05-02 Bernard Jankelson Adjustable headband carrying electrodes for electrically stimulating the facial and mandibular nerves
US3744482A (en) 1971-06-29 1973-07-10 Hittman Ass Inc Dry contact electrode with amplifier for physiological signals
US3817254A (en) 1972-05-08 1974-06-18 Medtronic Inc Transcutaneous stimulator and stimulation method
US3882846A (en) 1973-04-04 1975-05-13 Nasa Insulated electrocardiographic electrodes
US3862633A (en) 1974-05-06 1975-01-28 Kenneth C Allison Electrode
US3973557A (en) 1975-04-21 1976-08-10 Allison Kenneth C Electrode
US4220159A (en) 1976-04-23 1980-09-02 Biomedical International Company Electrode
US4166457A (en) 1976-08-16 1979-09-04 University Of Utah Research Institute Fluid self-sealing bioelectrode
US4144893A (en) 1976-09-22 1979-03-20 Batrow Laboratories, Inc. Neuromuscular therapy device
US4324253A (en) 1977-01-28 1982-04-13 Greene Ronald W Transcutaneous pain control and/or muscle stimulating apparatus
US4182346A (en) 1977-06-02 1980-01-08 Biomedical International Company Electrode
US4215696A (en) 1978-03-20 1980-08-05 Graphic Controls Corporation Biomedical electrode with pressurized skin contact
US4177819A (en) 1978-03-30 1979-12-11 Kofsky Harvey I Muscle stimulating apparatus
US4196737A (en) 1978-04-21 1980-04-08 C. R. Bard, Inc. Transcutaneous electrode construction
CA1105565A (en) 1978-09-12 1981-07-21 Kaufman (John G.) Hospital Products Ltd. Electrosurgical electrode
US4669468A (en) 1979-06-15 1987-06-02 American Hospital Supply Corporation Capacitively coupled indifferent electrode
US4503863A (en) 1979-06-29 1985-03-12 Katims Jefferson J Method and apparatus for transcutaneous electrical stimulation
US4458696A (en) 1979-08-07 1984-07-10 Minnesota Mining And Manufacturing Company T.E.N.S. Electrode
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4387714A (en) 1981-05-13 1983-06-14 Purdue Research Foundation Electrosurgical dispersive electrode
DE3363213D1 (en) * 1982-01-18 1986-06-05 Medtronic Inc Electrically conductive compositions and electrodes utilizing same
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US5003978A (en) 1985-08-21 1991-04-02 Technology 21, Inc. Non-polarizable dry biomedical electrode
US4865048A (en) 1987-12-31 1989-09-12 Eckerson Harold D Method and apparatus for drug free neurostimulation
JPH0235755U (en) * 1988-08-31 1990-03-08
US5052391A (en) 1990-10-22 1991-10-01 R.F.P., Inc. High frequency high intensity transcutaneous electrical nerve stimulator and method of treatment
US5299569A (en) 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
AU2339792A (en) 1991-07-22 1993-02-23 Cyberonics, Inc. Treatment of respiratory disorders by nerve stimulation
US5782874A (en) * 1993-05-28 1998-07-21 Loos; Hendricus G. Method and apparatus for manipulating nervous systems
US5487759A (en) 1993-06-14 1996-01-30 Bastyr; Charles A. Nerve stimulating device and associated support device
US5458141A (en) 1993-08-04 1995-10-17 Quinton Instrument Company Abrasive skin electrode
US5458625A (en) 1994-05-04 1995-10-17 Kendall; Donald E. Transcutaneous nerve stimulation device and method for using same
US5512057A (en) 1994-11-14 1996-04-30 Medserv Group, Inc. Interferential stimulator for applying localized stimulation
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US5903516A (en) 1996-05-08 1999-05-11 Mayo Foundation For Medical Education And Research Acoustic force generator for detection, imaging and information transmission using the beat signal of multiple intersecting sonic beams
AU3304997A (en) 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
AU2946697A (en) 1996-06-06 1998-01-05 University Of Western Ontario, The Electrotherapy device using low frequency magnetic pulses
US6029090A (en) 1997-01-27 2000-02-22 Herbst; Ewa Multi-functional electrical stimulation system
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US6757556B2 (en) 1998-05-26 2004-06-29 Ineedmd. Com Electrode sensor
US6463327B1 (en) 1998-06-11 2002-10-08 Cprx Llc Stimulatory device and methods to electrically stimulate the phrenic nerve
US20050137644A1 (en) 1998-10-26 2005-06-23 Boveja Birinder R. Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders
US6351674B2 (en) 1998-11-23 2002-02-26 Synaptic Corporation Method for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6587719B1 (en) 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US6610713B2 (en) 2000-05-23 2003-08-26 North Shore - Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6871099B1 (en) 2000-08-18 2005-03-22 Advanced Bionics Corporation Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain
US6567695B1 (en) 2000-11-24 2003-05-20 Woodside Biomedical, Inc. Electro-acupuncture device with stimulation electrode assembly
US6738667B2 (en) 2000-12-28 2004-05-18 Medtronic, Inc. Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation
US6609025B2 (en) 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6735480B2 (en) 2001-06-29 2004-05-11 Abbott Laboratories Electro-acupuncture device with D-shaped stimulation electrodes
US7885709B2 (en) 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7778711B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US8571653B2 (en) 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US7734355B2 (en) 2001-08-31 2010-06-08 Bio Control Medical (B.C.M.) Ltd. Treatment of disorders by unidirectional nerve stimulation
WO2003066155A2 (en) 2002-02-01 2003-08-14 The Cleveland Clinic Foundation Methods of affecting hypothalamic-related conditions
US6838963B2 (en) 2002-04-01 2005-01-04 Med-El Elektromedizinische Geraete Gmbh Reducing effects of magnetic and electromagnetic fields on an implant's magnet and/or electronics
US20120303080A1 (en) 2003-06-13 2012-11-29 Bio Control Medical (B.C.M.) Ltd. Parasympathetic nerve stimulation
KR100553516B1 (en) 2002-06-24 2006-02-20 정종필 Apparatus for inducing alpha -wave by electrical stimulation
US7294101B2 (en) 2002-12-21 2007-11-13 Neuropace, Inc. Means and methods for treating headaches
US20040172084A1 (en) 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7153256B2 (en) 2003-03-07 2006-12-26 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
US20050187590A1 (en) 2003-05-11 2005-08-25 Boveja Birinder R. Method and system for providing therapy for autism by providing electrical pulses to the vagus nerve(s)
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US10322284B2 (en) 2003-07-18 2019-06-18 The John Hopkins University Method for treating nausea and vomiting by vagus nerve stimulation with selectable stimulation modes
US7418292B2 (en) 2003-10-01 2008-08-26 Medtronic, Inc. Device and method for attenuating an immune response
US20050075702A1 (en) 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator
US8190248B2 (en) 2003-10-16 2012-05-29 Louisiana Tech University Foundation, Inc. Medical devices for the detection, prevention and/or treatment of neurological disorders, and methods related thereto
US8086318B2 (en) 2004-02-12 2011-12-27 Ndi Medical, Llc Portable assemblies, systems, and methods for providing functional or therapeutic neurostimulation
EP1742700A4 (en) 2004-03-02 2008-05-28 Cvrx Inc External baroreflex activation
CN1976738B (en) 2004-04-23 2010-09-01 诺沃库勒有限公司 Treating a tumor or the like with an electric field
US7601115B2 (en) 2004-05-24 2009-10-13 Neuronetics, Inc. Seizure therapy method and apparatus
US7173437B2 (en) 2004-06-10 2007-02-06 Quantum Applied Science And Research, Inc. Garment incorporating embedded physiological sensors
US20080027513A1 (en) 2004-07-09 2008-01-31 Advanced Bionics Corporation Systems And Methods For Using A Butterfly Coil To Communicate With Or Transfer Power To An Implantable Medical Device
WO2006019764A2 (en) 2004-07-15 2006-02-23 Northstar Neuroscience, Inc. Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy
CA2477615A1 (en) 2004-07-15 2006-01-15 Quantum Applied Science And Research, Inc. Unobtrusive measurement system for bioelectric signals
US7337006B2 (en) 2004-09-08 2008-02-26 Spinal Modulation, Inc. Methods and systems for modulating neural tissue
WO2006041648A2 (en) 2004-10-04 2006-04-20 Peerlead Medical, Inc. A capacitive medical electrode
US7734340B2 (en) 2004-10-21 2010-06-08 Advanced Neuromodulation Systems, Inc. Stimulation design for neuromodulation
DK1833552T3 (en) 2004-12-07 2010-08-02 Standen Ltd Electrodes for applying an electric field in-vivo for an extended period of time
US9089691B2 (en) 2004-12-07 2015-07-28 Cardiac Pacemakers, Inc. Stimulator for auricular branch of vagus nerve
US20070038264A1 (en) 2004-12-21 2007-02-15 Jaax Kristen N Methods and systems for treating autism
CA2593079C (en) 2004-12-27 2014-08-19 North Shore-Long Island Jewish Research Institute Treating inflammatory disorders by electrical vagus nerve stimulation
US20080051852A1 (en) 2006-01-21 2008-02-28 Cerbomed Gmbh Device and method for the transdermal stimulation of a nerve of the human body
US20070276449A1 (en) 2005-06-15 2007-11-29 Med-Lectric Corporation Interactive transcutaneous electrical nerve stimulation device
US8660647B2 (en) 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US7555344B2 (en) 2005-10-28 2009-06-30 Cyberonics, Inc. Selective neurostimulation for treating epilepsy
US8914122B2 (en) 2009-03-20 2014-12-16 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US8868177B2 (en) 2009-03-20 2014-10-21 ElectroCore, LLC Non-invasive treatment of neurodegenerative diseases
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US8812112B2 (en) 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US8676330B2 (en) 2009-03-20 2014-03-18 ElectroCore, LLC Electrical and magnetic stimulators used to treat migraine/sinus headache and comorbid disorders
US20100241188A1 (en) 2009-03-20 2010-09-23 Electrocore, Inc. Percutaneous Electrical Treatment Of Tissue
EP1948301B8 (en) * 2005-11-10 2014-03-12 ElectroCore LLC Electrical stimulation treatment of bronchial constriction
US8262556B2 (en) 2005-12-19 2012-09-11 Neuralieve, Inc. Magnetic pulsing system for inducing electric currents in a human body
US7672728B2 (en) 2005-12-28 2010-03-02 Cardiac Pacemakers, Inc. Neural stimulator to treat sleep disordered breathing
US8868172B2 (en) 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US7660636B2 (en) 2006-01-04 2010-02-09 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of dysphagia
WO2007127953A2 (en) 2006-04-27 2007-11-08 Eyad Kishawi Device and method for non-invasive, localized neural stimulation utilizing hall effect phenomenon
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
DE102006023824B4 (en) 2006-05-20 2010-01-28 Cerbomed Gmbh Apparatus for transcutaneous application of a stimulus or for transcutaneous detecting a parameter
US9630003B2 (en) * 2006-06-15 2017-04-25 Htk Enterprises, Inc. Non-invasive neuro stimulation system
US20080097549A1 (en) * 2006-09-01 2008-04-24 Colbaugh Michael E Electrode Assembly and Method of Using Same
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
EP2069013A2 (en) 2006-10-02 2009-06-17 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US7797041B2 (en) 2006-10-11 2010-09-14 Cardiac Pacemakers, Inc. Transcutaneous neurostimulator for modulating cardiovascular function
US8301239B2 (en) 2007-01-18 2012-10-30 Cardiac Pacemakers, Inc. Systems, devices and methods for acute autonomic stimulation
US7949403B2 (en) * 2007-02-27 2011-05-24 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of neurological disorders
US7869884B2 (en) 2007-04-26 2011-01-11 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US8755892B2 (en) 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets
CA2733081C (en) 2007-08-06 2015-12-15 Great Lakes Biosciences, Llc Methods and apparatus for electrical stimulation of tissues using signals that minimize the effects of tissue impedance
US8260439B2 (en) * 2007-11-16 2012-09-04 Ethicon, Inc. Nerve stimulation patches and methods for stimulating selected nerves
US8170683B2 (en) * 2007-12-14 2012-05-01 Ethicon, Inc. Dermatome stimulation devices and methods
JP2009233024A (en) 2008-03-26 2009-10-15 Terumo Corp Vagus nerve stimulation system
EP2116275A1 (en) 2008-05-09 2009-11-11 Eumedic Limited A plurality of electrons for use in the restoration of a patient's health
BRPI0912602A2 (en) 2008-05-13 2019-06-04 Cerbomed Gmbh method to intensify neural tissue operation
US20100286553A1 (en) 2009-05-08 2010-11-11 Feler Claudio A Devices and Methods for Screening of Vagal Nerve Stimulation

Also Published As

Publication number Publication date
EP2686060A1 (en) 2014-01-22
US20160136423A1 (en) 2016-05-19
IL227868A (en) 2019-02-28
US9067054B2 (en) 2015-06-30
WO2012121750A1 (en) 2012-09-13
MX351494B (en) 2017-10-17
EP2962725A1 (en) 2016-01-06
AU2011361696A1 (en) 2013-08-29
MX2013010215A (en) 2014-04-25
US20110276112A1 (en) 2011-11-10
CN103517732B (en) 2016-09-07
US9242092B2 (en) 2016-01-26
US20140236272A1 (en) 2014-08-21
US8874227B2 (en) 2014-10-28
US20150297889A1 (en) 2015-10-22
EP2686060A4 (en) 2014-08-27
AU2011361696B2 (en) 2018-11-15
JP2017080490A (en) 2017-05-18
JP2014510586A (en) 2014-05-01
AU2019201050A1 (en) 2019-03-07
CN103517732A (en) 2014-01-15
US9717904B2 (en) 2017-08-01
CA2826835C (en) 2016-10-11
EP2962724A1 (en) 2016-01-06
CA2826835A1 (en) 2012-09-13

Similar Documents

Publication Publication Date Title
US8805548B2 (en) Headband for external occipital neurostimulation
US9717904B2 (en) Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
Keller et al. Electrodes for transcutaneous (surface) electrical stimulation
US8914122B2 (en) Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US8874205B2 (en) Device and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation
US9174066B2 (en) Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US8914123B2 (en) Apparatus for electro-inhibition of facial muscles
Reilly Applied bioelectricity: from electrical stimulation to electropathology
AU2010319602B2 (en) Synergistic muscle activation device
EP1523368A1 (en) Apparatus for the application of electrical pulses to the human body
MX2011007037A (en) Methods for reducing discomfort during electrostimulation, and compositions and apparatus therefor.
WO2013177006A3 (en) Methods and devices for modulating excitable tissue of the exiting spinal nerves
NZ591097A (en) Treatment of sweating and hyperhidrosis
WO2007135667A3 (en) Method and device for enhanced blood flow
KR20100120281A (en) System and method for generating complex bioeletric stimulation signals while conserving power
CN101687093A (en) Array stimulator
DK2575731T3 (en) electrode
WO2012118660A3 (en) Electrical ablation devices and methods
WO2010096776A3 (en) Systems and methods of powered muscle stimulation using an energy guidance field
WO2011159923A3 (en) Implantable micro-component electrodes
WO2014016700A3 (en) Implant sleep apnea treatment device including an antenna
CN105377359A (en) Detecting cutaneous electrode peeling using electrode-skin impedance
WO2007120305A3 (en) Electrode arrangement for nerve stimulation and methods of treating disorders
WO2006093686A3 (en) Lead electrode for use in an mri-safe implantable medical device
MX346885B (en) Implantable lead.

Legal Events

Date Code Title Description
FF Patent granted