IL218316D0 - Combination therapy with nanoparicle compositions of taxane and hedgehog inhibitors - Google Patents

Combination therapy with nanoparicle compositions of taxane and hedgehog inhibitors

Info

Publication number
IL218316D0
IL218316D0 IL218316A IL21831612A IL218316D0 IL 218316 D0 IL218316 D0 IL 218316D0 IL 218316 A IL218316 A IL 218316A IL 21831612 A IL21831612 A IL 21831612A IL 218316 D0 IL218316 D0 IL 218316D0
Authority
IL
Israel
Prior art keywords
nanoparicle
taxane
compositions
combination therapy
hedgehog inhibitors
Prior art date
Application number
IL218316A
Other versions
IL218316A (en
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US23681309P priority Critical
Priority to PCT/US2010/046684 priority patent/WO2011025838A1/en
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of IL218316D0 publication Critical patent/IL218316D0/en
Publication of IL218316A publication Critical patent/IL218316A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL218316A 2009-08-25 2012-02-26 Use of nanoparticles comprising taxane for treating cancer in combination with hedgehog inhibitors IL218316A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US23681309P true 2009-08-25 2009-08-25
PCT/US2010/046684 WO2011025838A1 (en) 2009-08-25 2010-08-25 Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors

Publications (2)

Publication Number Publication Date
IL218316D0 true IL218316D0 (en) 2012-04-30
IL218316A IL218316A (en) 2016-04-21

Family

ID=43628371

Family Applications (1)

Application Number Title Priority Date Filing Date
IL218316A IL218316A (en) 2009-08-25 2012-02-26 Use of nanoparticles comprising taxane for treating cancer in combination with hedgehog inhibitors

Country Status (27)

Country Link
US (2) US20130045240A1 (en)
EP (2) EP3103452A1 (en)
JP (1) JP2013503174A (en)
KR (1) KR20120053052A (en)
CN (1) CN102573832B (en)
AU (1) AU2010286670B2 (en)
BR (1) BR112012004149A2 (en)
CA (1) CA2772301A1 (en)
CR (1) CR20120115A (en)
DK (1) DK2470173T3 (en)
ES (1) ES2577024T3 (en)
HK (1) HK1172550A1 (en)
HR (1) HRP20160551T8 (en)
HU (1) HUE029094T2 (en)
IL (1) IL218316A (en)
IN (1) IN2012DN02018A (en)
MX (1) MX340670B (en)
MY (1) MY162514A (en)
NI (1) NI201200030A (en)
NZ (1) NZ598588A (en)
PL (1) PL2470173T3 (en)
PT (1) PT2470173E (en)
RU (1) RU2561055C2 (en)
SG (2) SG178873A1 (en)
UA (1) UA110196C2 (en)
WO (1) WO2011025838A1 (en)
ZA (1) ZA201201531B (en)

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Also Published As

Publication number Publication date
SG10201609290PA (en) 2016-12-29
HUE029094T2 (en) 2017-02-28
PL2470173T3 (en) 2016-11-30
SG178873A1 (en) 2012-04-27
MX340670B (en) 2016-07-20
PT2470173E (en) 2016-06-15
IL218316A (en) 2016-04-21
ES2577024T3 (en) 2016-07-12
WO2011025838A1 (en) 2011-03-03
MY162514A (en) 2017-06-15
ZA201201531B (en) 2013-05-29
AU2010286670B2 (en) 2016-04-21
CN102573832A (en) 2012-07-11
RU2012111235A (en) 2013-10-10
EP2470173A4 (en) 2013-06-19
CR20120115A (en) 2012-09-04
CA2772301A1 (en) 2011-03-03
NI201200030A (en) 2012-12-06
NZ598588A (en) 2014-05-30
MX2012002460A (en) 2012-05-08
US20130045240A1 (en) 2013-02-21
CN102573832B (en) 2015-07-22
BR112012004149A2 (en) 2016-03-22
UA110196C2 (en) 2015-12-10
EP2470173A1 (en) 2012-07-04
RU2561055C2 (en) 2015-08-20
US20140072630A1 (en) 2014-03-13
HRP20160551T1 (en) 2016-09-23
HK1172550A1 (en) 2017-07-21
KR20120053052A (en) 2012-05-24
EP2470173B1 (en) 2016-04-27
JP2013503174A (en) 2013-01-31
EP3103452A1 (en) 2016-12-14
HRP20160551T8 (en) 2016-11-18
AU2010286670A1 (en) 2012-03-29
IN2012DN02018A (en) 2015-07-31
DK2470173T3 (en) 2016-06-06

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