IL216825D0 - Triazine derivatives, processes for producing the same, compositions comprising the same and uses thereof - Google Patents

Triazine derivatives, processes for producing the same, compositions comprising the same and uses thereof

Info

Publication number
IL216825D0
IL216825D0 IL21682511A IL21682511A IL216825D0 IL 216825 D0 IL216825 D0 IL 216825D0 IL 21682511 A IL21682511 A IL 21682511A IL 21682511 A IL21682511 A IL 21682511A IL 216825 D0 IL216825 D0 IL 216825D0
Authority
IL
Israel
Prior art keywords
same
compositions
processes
uses
producing
Prior art date
Application number
IL21682511A
Other versions
IL216825A (en
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US18505209P priority Critical
Priority to PCT/US2010/037570 priority patent/WO2010144338A1/en
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of IL216825D0 publication Critical patent/IL216825D0/en
Publication of IL216825A publication Critical patent/IL216825A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
IL216825A 2009-06-08 2011-12-07 Triazine derivatives, processes for producing the same, compositions comprising the same and uses thereof IL216825A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US18505209P true 2009-06-08 2009-06-08
PCT/US2010/037570 WO2010144338A1 (en) 2009-06-08 2010-06-07 Triazine derivatives and their therapeutical applications

Publications (2)

Publication Number Publication Date
IL216825D0 true IL216825D0 (en) 2012-02-29
IL216825A IL216825A (en) 2016-10-31

Family

ID=43309171

Family Applications (1)

Application Number Title Priority Date Filing Date
IL216825A IL216825A (en) 2009-06-08 2011-12-07 Triazine derivatives, processes for producing the same, compositions comprising the same and uses thereof

Country Status (10)

Country Link
US (1) US20120238576A1 (en)
EP (1) EP2440050A4 (en)
JP (1) JP2012529511A (en)
KR (1) KR101460095B1 (en)
CN (2) CN105175409A (en)
AU (2) AU2010259002B2 (en)
BR (1) BRPI1010881A2 (en)
CA (1) CA2764785C (en)
IL (1) IL216825A (en)
WO (1) WO2010144338A1 (en)

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SG10201403696UA (en) 2009-06-29 2014-10-30 Agios Pharmaceuticals Inc Therapeutic compounds and compositions
WO2011050211A2 (en) 2009-10-21 2011-04-28 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
ES2594402T3 (en) 2009-10-21 2016-12-20 Agios Pharmaceuticals, Inc. Methods and compositions for disorders related to cell proliferation
MX2012009561A (en) * 2010-02-17 2012-11-23 Amgen Inc Aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain.
HUE040086T2 (en) 2010-08-10 2019-02-28 Rempex Pharmaceuticals Inc Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN108451955A (en) 2011-05-03 2018-08-28 安吉奥斯医药品有限公司 Pyruvate kinase activators for use in therapy
RU2011122942A (en) * 2011-06-08 2012-12-20 Общество С Ограниченной Ответственностью "Асинэкс Медхим" New kinase inhibitors
CN102827170A (en) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 Active treatment compositions and use method thereof
CN102827073A (en) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 Therapeutically active compositions and application methods thereof
US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
HUE038403T2 (en) 2012-01-06 2018-10-29 Agios Pharmaceuticals Inc Therapeutically active compounds and their methods of use
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
CN102827156A (en) * 2012-09-11 2012-12-19 湖南欧亚生物有限公司 Novel industrial synthetic method of dasatinib
MX2015004762A (en) 2012-10-15 2016-05-24 Agios Pharmaceuticals Inc Therapeutic compounds and compositions.
US9073875B2 (en) 2012-11-20 2015-07-07 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of indoleamine 2,3-dioxygenase
US9365526B2 (en) 2012-12-31 2016-06-14 Sun Pharmaceutical Industries Limited Process for the preparation of dasatinib and its intermediates
JP2016509594A (en) 2013-01-04 2016-03-31 レンペックス・ファーマシューティカルズ・インコーポレイテッド Boronic acid derivatives and their therapeutic use
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EA201591004A1 (en) 2013-01-04 2016-02-29 Ремпекс Фармасьютикалз, Инк. Boronic acid derivatives and their therapeutic use
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2015003360A2 (en) * 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
CN105473560A (en) * 2013-07-11 2016-04-06 安吉奥斯医药品有限公司 Therapeutically active compounds and use methods thereof
WO2015003355A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
CN105517996B (en) * 2013-07-11 2019-03-26 安吉奥斯医药品有限公司 Therapeutical active compound and its application method
WO2015006592A1 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer
SG10201709187TA (en) 2013-08-02 2017-12-28 Agios Pharmaceuticals Inc Therapeutically active compounds and their methods of use
WO2015018060A1 (en) * 2013-08-09 2015-02-12 Agios Pharmaceuticals, Inc. Crystalline forms of therapeutically active compounds and use thereof
CN103483289B (en) * 2013-09-06 2016-01-27 浙江科源化工有限公司 One kind of 2-amino -N- (2- chloro-6-methylphenyl) thiazole-5-carboxamide synthesis of
CA2942070A1 (en) * 2014-03-14 2015-09-17 Agios Pharmaceuticals, Inc. Pharmaceutical compositions of therapeutically active compounds
WO2015138839A1 (en) 2014-03-14 2015-09-17 Agios Pharmaceuticals, Inc. Pharmaceutical compositions of therapeutically active compounds
US9687497B1 (en) 2014-05-05 2017-06-27 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
CA2947041A1 (en) 2014-05-19 2015-11-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10206937B2 (en) 2014-07-01 2019-02-19 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN104163818A (en) * 2014-07-15 2014-11-26 南昌大学 2-amino oxazole compound and preparation method and application thereof
JP6356364B1 (en) 2015-05-20 2018-07-11 アムジエン・インコーポレーテツド Triazole agonist of Apj receptor
AU2016303614A1 (en) 2015-08-05 2018-02-15 Agios Pharmaceuticals, Inc. Methods of preparing 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diols and 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diamines
CN105541823B (en) * 2016-02-03 2018-03-06 三峡大学 Triazine compounds, a process for preparing an oxazoline ring containing in its application anticancer drugs
EP3452466A1 (en) 2016-05-03 2019-03-13 Amgen Inc. Heterocyclic triazole compounds as agonists of the apj receptor
KR20190025953A (en) 2016-06-30 2019-03-12 큐펙스 바이오파마 인코포레이티드 Boronic acid derivatives and their therapeutic uses
CN106883235B (en) * 2016-12-29 2019-04-30 天津国际生物医药联合研究院 The preparation and application of furodiazole compound

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AT396978T (en) * 1999-10-07 2008-06-15 Amgen Inc Triazine-kinase inhibitor
DE60120194T2 (en) * 2000-09-15 2007-03-29 Vertex Pharmaceuticals Inc., Cambridge Pyrazole compounds as protein kinase inhibitors-
EP1702920B1 (en) * 2000-12-21 2011-10-12 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
WO2003078423A1 (en) * 2002-03-15 2003-09-25 Vertex Pharmaceuticals, Inc. Compositions useful as inhibitors of protein kinases
DE60327999D1 (en) * 2002-03-15 2009-07-30 Vertex Pharma Azolylaminoazine as inhibitors of protein kinases
AT468336T (en) * 2002-03-15 2010-06-15 Vertex Pharma Azolylaminoazine as protein kinase inhibitors
AR061185A1 (en) * 2006-05-26 2008-08-13 Chugai Pharmaceutical Co Ltd Heterocyclic compounds as HSP90 inhibitors. pharmaceutical compositions.
CN101583365B (en) * 2006-12-15 2012-09-26 阿布拉西斯生物科学公司 Triazine derivatives and their therapeutical applications
TW200906818A (en) * 2007-07-31 2009-02-16 Astrazeneca Ab Chemical compounds
EP2291372A4 (en) * 2008-05-19 2012-04-25 Burnham Inst Medical Research Intestinal alkaline phosphatase modulators and uses thereof
RU2010154502A (en) * 2008-06-11 2012-07-20 Астразенека Аб (Se) Tricyclic 2,4-diamino-l, 3,5-triazine derivatives useful for the treatment of cancer and myeloproliferative disorders
BRPI1010887A2 (en) * 2009-06-08 2016-12-27 California Capital Equity Llc triazine derivatives and their therapeutic applications.
BRPI1011527A2 (en) * 2009-06-09 2016-07-26 California Capital Equity Llc triazine derivatives substituted ureidophenyl and their therapeutic applications.
JP5785940B2 (en) * 2009-06-09 2015-09-30 アブラクシス バイオサイエンス, エルエルシー Triazine derivatives and their therapeutic applications
BRPI1011319A2 (en) * 2009-06-09 2016-06-21 California Capital Equity Llc Benzyl-substituted derivatives of triazine and its therapeutic applications

Also Published As

Publication number Publication date
AU2010259002B2 (en) 2014-03-20
AU2010259002A1 (en) 2012-01-12
JP2012529511A (en) 2012-11-22
IL216825A (en) 2016-10-31
CN102573485B (en) 2014-11-26
WO2010144338A1 (en) 2010-12-16
EP2440050A4 (en) 2013-04-03
US20120238576A1 (en) 2012-09-20
CN102573485A (en) 2012-07-11
CA2764785C (en) 2015-10-27
AU2014203330A1 (en) 2014-07-10
KR20120016674A (en) 2012-02-24
KR101460095B1 (en) 2014-11-10
CN105175409A (en) 2015-12-23
CA2764785A1 (en) 2010-12-16
BRPI1010881A2 (en) 2016-05-31
EP2440050A1 (en) 2012-04-18

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