IL210406D0 - Pyrrolopyridinylpyrimidin - 2 - ylamine derivatives - Google Patents

Pyrrolopyridinylpyrimidin - 2 - ylamine derivatives

Info

Publication number
IL210406D0
IL210406D0 IL21040610A IL21040610A IL210406D0 IL 210406 D0 IL210406 D0 IL 210406D0 IL 21040610 A IL21040610 A IL 21040610A IL 21040610 A IL21040610 A IL 21040610A IL 210406 D0 IL210406 D0 IL 210406D0
Authority
IL
Israel
Prior art keywords
pyrrolopyridinylpyrimidin
ylamine derivatives
ylamine
derivatives
Prior art date
Application number
IL21040610A
Other versions
IL210406A (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE200810031517 priority Critical patent/DE102008031517A1/en
Priority to PCT/EP2009/004013 priority patent/WO2010000364A1/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL210406D0 publication Critical patent/IL210406D0/en
Publication of IL210406A publication Critical patent/IL210406A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
IL210406A 2008-07-03 2010-12-30 Pyrrolopyridinylpyrimidin- 2-ylamine derivatives IL210406A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE200810031517 DE102008031517A1 (en) 2008-07-03 2008-07-03 Pyrrolopyridinyl-pyrimidin-2-yl-amine derivatives
PCT/EP2009/004013 WO2010000364A1 (en) 2008-07-03 2009-06-04 Pyrrolopyridinylpyrimidin-2-ylamine derivatives

Publications (2)

Publication Number Publication Date
IL210406D0 true IL210406D0 (en) 2011-03-31
IL210406A IL210406A (en) 2014-11-30

Family

ID=40849173

Family Applications (1)

Application Number Title Priority Date Filing Date
IL210406A IL210406A (en) 2008-07-03 2010-12-30 Pyrrolopyridinylpyrimidin- 2-ylamine derivatives

Country Status (16)

Country Link
US (1) US8420820B2 (en)
EP (1) EP2291375B1 (en)
JP (2) JP5587874B2 (en)
KR (1) KR20110027835A (en)
CN (1) CN102056926B (en)
AR (1) AR072792A1 (en)
AU (1) AU2009266090B2 (en)
BR (1) BRPI0913832A2 (en)
CA (1) CA2729725C (en)
DE (1) DE102008031517A1 (en)
EA (1) EA201100125A1 (en)
ES (1) ES2564204T3 (en)
IL (1) IL210406A (en)
MX (1) MX2010013919A (en)
WO (1) WO2010000364A1 (en)
ZA (1) ZA201100876B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008031517A1 (en) * 2008-07-03 2010-01-07 Merck Patent Gmbh Pyrrolopyridinyl-pyrimidin-2-yl-amine derivatives
DE102009060174A1 (en) * 2009-12-23 2011-06-30 Merck Patent GmbH, 64293 Pyrrolopyridinyl-pyrimidin-2-yl-amine derivatives
BR112012026249A2 (en) * 2010-04-16 2016-11-29 Ac Immune Sa compound, radiopharmaceutical formulation, pharmaceutical composition, use of the compound, mixing, methods of collecting data for the diagnosis of an amyloid-associated disease or condition, determining the extent of amyloidogenic plaque burden in a tissue and / or body fluid, collecting data to determine a predisposition to an amyloid-associated disease or condition in a patient, to collect data to monitor a minimal residual disease in a patient following treatment with an antibody or vaccine composition, to collect data to predict a patient's ability to react. a patient being treated with an antibody or vaccine composition, and, test kit.
CA2799156A1 (en) 2010-05-12 2011-11-17 Abbvie Inc. Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases
DE102010050558A1 (en) * 2010-11-05 2012-05-10 Merck Patent Gmbh 1H-pyrrolo [2,3-b] pyridine
DE102010053347A1 (en) * 2010-12-03 2012-06-06 Merck Patent Gmbh 3-hetaryl-substituted pyrrolo [2,3-b] pyridine-derivative as PDK1 inhibitors
DE102011009961A1 (en) 2011-02-01 2012-08-02 Merck Patent Gmbh 7-azaindole derivatives
DE102011105469A1 (en) * 2011-06-24 2012-12-27 Merck Patent Gmbh 7-azaindole derivatives
EA025186B1 (en) 2012-06-29 2016-11-30 Пфайзер Инк. NOVEL 4-(SUBSTITUTED-AMINO)-7H-PYRROLO[2,3-d]PYRIMIDINES AS LRRK2 INHIBITORS
US20140303121A1 (en) 2013-03-15 2014-10-09 Plexxikon Inc. Heterocyclic compounds and uses thereof
SI2970265T1 (en) 2013-03-15 2018-10-30 Plexxikon Inc. Heterocyclic compounds and uses thereof
JP6487921B2 (en) 2013-12-17 2019-03-20 ファイザー・インク Novel 3,4-disubstituted-1H-pyrrolo [2,3-b] pyridines and 4,5-disubstituted-7H-pyrrolo [2,3-c] pyridazines as LRRK2 inhibitors
CN106432246A (en) * 2015-08-05 2017-02-22 广东东阳光药业有限公司 Heteroaromatic compound and application thereof to drug
MX2018003215A (en) 2015-09-14 2018-06-08 Pfizer Novel imidazo [4,5-c] quinoline and imidazo [4,5-c][1,5] naphthyridine derivatives as lrrk2 inhibitors.
US20190322658A1 (en) * 2018-04-24 2019-10-24 Merck Patent Gmbh Antiproliferation compounds and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747469A (en) 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
GB9904387D0 (en) 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
PT1730146E (en) * 2004-03-30 2011-07-11 Vertex Pharma Azaindoles useful as inhibitors of jak and other protein kinases
WO2006124863A2 (en) 2005-05-16 2006-11-23 Irm Llc Pyrrolopyridine derivatives as protein kinase inhibitors
DE102006012617A1 (en) 2006-03-20 2007-09-27 Merck Patent Gmbh 4- (pyrrolopyridinyl) -pyrimidinyl-2-amine derivatives
DE102007028515A1 (en) * 2007-06-21 2008-12-24 Merck Patent Gmbh 6- (pyrrolopyridinyl) -pyrimidinyl-2-amine derivatives
DE102008031517A1 (en) * 2008-07-03 2010-01-07 Merck Patent Gmbh Pyrrolopyridinyl-pyrimidin-2-yl-amine derivatives

Also Published As

Publication number Publication date
JP5587874B2 (en) 2014-09-10
WO2010000364A1 (en) 2010-01-07
KR20110027835A (en) 2011-03-16
JP5955902B2 (en) 2016-07-20
CA2729725A1 (en) 2010-01-07
AU2009266090B2 (en) 2014-04-03
IL210406A (en) 2014-11-30
AU2009266090A1 (en) 2010-01-07
DE102008031517A1 (en) 2010-01-07
AR072792A1 (en) 2010-09-22
US20110218198A1 (en) 2011-09-08
CN102056926A (en) 2011-05-11
WO2010000364A8 (en) 2011-01-06
JP2011526260A (en) 2011-10-06
ES2564204T3 (en) 2016-03-18
EP2291375A1 (en) 2011-03-09
MX2010013919A (en) 2011-02-21
CA2729725C (en) 2016-11-08
CN102056926B (en) 2013-10-16
EP2291375B1 (en) 2016-01-06
ZA201100876B (en) 2011-10-26
EA201100125A1 (en) 2011-08-30
US8420820B2 (en) 2013-04-16
JP2014240397A (en) 2014-12-25
BRPI0913832A2 (en) 2015-10-20

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Legal Events

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KB Patent renewed
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