IL195494D0 - Ob-fold domains - Google Patents

Ob-fold domains

Info

Publication number
IL195494D0
IL195494D0 IL195494A IL19549408A IL195494D0 IL 195494 D0 IL195494 D0 IL 195494D0 IL 195494 A IL195494 A IL 195494A IL 19549408 A IL19549408 A IL 19549408A IL 195494 D0 IL195494 D0 IL 195494D0
Authority
IL
Israel
Prior art keywords
ob
fold domains
domains
fold
Prior art date
Application number
IL195494A
Other versions
IL195494A (en
Original Assignee
Waikatolink Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US80910506P priority Critical
Priority to PCT/NZ2007/000125 priority patent/WO2007139397A1/en
Application filed by Waikatolink Ltd filed Critical Waikatolink Ltd
Publication of IL195494D0 publication Critical patent/IL195494D0/en
Publication of IL195494A publication Critical patent/IL195494A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y601/00Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01012Aspartate-tRNA ligase (6.1.1.12)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
IL195494A 2006-05-26 2008-11-25 Ob-fold domains IL195494A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US80910506P true 2006-05-26 2006-05-26
PCT/NZ2007/000125 WO2007139397A1 (en) 2006-05-26 2007-05-25 Ob fold domains

Publications (2)

Publication Number Publication Date
IL195494D0 true IL195494D0 (en) 2009-09-01
IL195494A IL195494A (en) 2014-11-30

Family

ID=38778843

Family Applications (1)

Application Number Title Priority Date Filing Date
IL195494A IL195494A (en) 2006-05-26 2008-11-25 Ob-fold domains

Country Status (10)

Country Link
US (1) US9181543B2 (en)
EP (1) EP2029620B1 (en)
JP (1) JP2009539346A (en)
CN (1) CN101506227A (en)
AU (1) AU2007268364B8 (en)
CA (1) CA2653752A1 (en)
IL (1) IL195494A (en)
NZ (1) NZ573407A (en)
WO (1) WO2007139397A1 (en)
ZA (1) ZA200810836B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1930342B1 (en) * 2006-12-04 2012-01-25 Institut Pasteur OB-fold used as scaffold for engineering new specific binders
AU2013200275B2 (en) * 2006-12-04 2014-08-14 Centre National De La Recherche Scientifique OB-fold used as scaffold for engineering new specific binders
EP2403864B1 (en) 2009-02-27 2015-08-12 Atyr Pharma, Inc. Polypeptide structural motifs associated with cell signaling activity
EP2408905B1 (en) 2009-03-16 2017-05-10 Pangu Biopharma Limited Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities
ES2560674T3 (en) * 2009-03-31 2016-02-22 Atyr Pharma, Inc. Compositions and procedures comprising aspartyl-tRNA synthetases with non-canonical biological activities
US8828395B2 (en) 2009-12-11 2014-09-09 Atyr Pharma, Inc. Antibodies that bind tyrosyl-tRNA synthetases
US20110150885A1 (en) * 2009-12-11 2011-06-23 Atyr Pharma, Inc. Aminoacyl trna synthetases for modulating hematopoiesis
CN106474462A (en) 2009-12-11 2017-03-08 Atyr 医药公司 For adjusting the aminoacyl tRNA synthetase of inflammation
EP2563380B1 (en) 2010-04-26 2018-05-30 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
CA2797362A1 (en) 2010-04-27 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
EP2563382B1 (en) 2010-04-27 2017-06-07 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases
CA2797271A1 (en) 2010-04-28 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
CN103097523B (en) 2010-04-29 2016-09-28 Atyr医药公司 The innovation for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of Asparaginyl-tRNA synthetase finds
CA2797393A1 (en) 2010-04-29 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
JP6008841B2 (en) 2010-05-03 2016-10-19 エータイアー ファーマ, インコーポレイテッド Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of methionyl tRNA synthetase
WO2011139988A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases
ES2623805T3 (en) 2010-05-03 2017-07-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic and antibody compositions related to phenylalanyl-alpha-tRNA synthetase protein fragments
CA2797277A1 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases
CN103096909A (en) 2010-05-04 2013-05-08 Atyr 医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-trna synthetases
EP2566499B1 (en) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
WO2011143482A2 (en) 2010-05-14 2011-11-17 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
CN103096914B (en) 2010-05-17 2015-08-12 Atyr医药公司 The innovation of the treatment relevant to the protein fragments of Leucyl-tRNA synthetase, diagnosis and antibody compositions finds
CN103096913B (en) 2010-05-27 2017-07-18 Atyr 医药公司 Treatment, diagnosis and the innovation of antibody compositions related to the protein fragments of glutaminyl tRNA synzyme is found
JP5906237B2 (en) 2010-06-01 2016-04-20 エータイアー ファーマ, インコーポレイテッド Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of lysyl tRNA synthetase
KR20130102534A (en) 2010-07-12 2013-09-17 에이티와이알 파마, 인코포레이티드 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
CN103118695B (en) 2010-07-12 2016-08-03 Atyr医药公司 The discovery for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of Glycyl-tRNA synthetase
KR20130100268A (en) * 2010-07-12 2013-09-10 에이티와이알 파마, 인코포레이티드 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
US8999321B2 (en) 2010-07-12 2015-04-07 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
US9029506B2 (en) 2010-08-25 2015-05-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases
CA2812795A1 (en) 2010-10-06 2012-04-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases
EP2469278A1 (en) * 2010-12-21 2012-06-27 Institut Pasteur Reagentless fluorescent biosensors from nanofitins, rational design methods to create reagentless fluorescent biosensors and methods of their use
WO2013022982A2 (en) 2011-08-09 2013-02-14 Atyr Pharma, Inc. Pegylated tyrosyl-trna synthetase polypeptides
US9816084B2 (en) 2011-12-06 2017-11-14 Atyr Pharma, Inc. Aspartyl-tRNA synthetases
WO2013086228A1 (en) 2011-12-06 2013-06-13 Atyr Pharma, Inc. Pegylated aspartyl-trna synthetase polypeptides
CN104220461A (en) * 2011-12-29 2014-12-17 Atyr医药公司 Aspartyl-trna synthetase-fc conjugates
WO2013123432A2 (en) 2012-02-16 2013-08-22 Atyr Pharma, Inc. Histidyl-trna synthetases for treating autoimmune and inflammatory diseases
ES2708565T3 (en) 2013-03-15 2019-04-10 Atyr Pharma Inc Conjugates of Fc-histidyl-tRNA synthetase
FR3004650B1 (en) * 2013-04-22 2015-05-29 Affilogic Topical composition comprising a variant of a wild-fold protein OB, as well as its preparation process
EP3483180A1 (en) 2017-11-14 2019-05-15 Affilogic Multi specific molecules

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9530A (en) * 1853-01-11 Improvement in porous cells for galvanic batteries
US103055A (en) * 1870-05-17 Jacob kinzer
US145008A (en) * 1873-11-25 Improvement in fog-signals
US255548A (en) * 1882-03-28 Wardrobe or folding bed
SE9400088D0 (en) * 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US6740734B1 (en) * 1994-01-14 2004-05-25 Biovitrum Ab Bacterial receptor structures
US7115396B2 (en) * 1998-12-10 2006-10-03 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US6818418B1 (en) * 1998-12-10 2004-11-16 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
DE19932688B4 (en) 1999-07-13 2009-10-08 Scil Proteins Gmbh Design of beta-sheet proteins of gamma-II-crystalline antibody-like
JP2004526419A (en) 2000-10-16 2004-09-02 フィロス インク. Protein scaffolds for antibody mimics and other binding proteins
EP1474161A4 (en) 2002-01-16 2005-06-29 Zyomyx Inc Engineered binding proteins
GB0416651D0 (en) 2004-07-26 2004-08-25 Proteo Target Aps Polypeptide
EP1930342B1 (en) 2006-12-04 2012-01-25 Institut Pasteur OB-fold used as scaffold for engineering new specific binders

Also Published As

Publication number Publication date
US9181543B2 (en) 2015-11-10
AU2007268364A1 (en) 2007-12-06
NZ573407A (en) 2012-09-28
EP2029620A1 (en) 2009-03-04
EP2029620A4 (en) 2010-12-29
EP2029620B1 (en) 2016-05-25
IL195494A (en) 2014-11-30
US20100048413A1 (en) 2010-02-25
ZA200810836B (en) 2010-07-28
AU2007268364A8 (en) 2013-05-16
CA2653752A1 (en) 2007-12-06
AU2007268364B8 (en) 2013-05-16
AU2007268364B2 (en) 2013-01-17
CN101506227A (en) 2009-08-12
JP2009539346A (en) 2009-11-19
WO2007139397A1 (en) 2007-12-06

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