IL194312D0 - Insulin derivative - Google Patents

Insulin derivative

Info

Publication number
IL194312D0
IL194312D0 IL19431208A IL19431208A IL194312D0 IL 194312 D0 IL194312 D0 IL 194312D0 IL 19431208 A IL19431208 A IL 19431208A IL 19431208 A IL19431208 A IL 19431208A IL 194312 D0 IL194312 D0 IL 194312D0
Authority
IL
Israel
Prior art keywords
insulin derivative
insulin
derivative
Prior art date
Application number
IL19431208A
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP06113709 priority Critical
Priority to EP06118260 priority
Priority to PCT/EP2007/054444 priority patent/WO2007128817A2/en
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL194312D0 publication Critical patent/IL194312D0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
IL19431208A 2006-05-09 2008-09-24 Insulin derivative IL194312D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06113709 2006-05-09
EP06118260 2006-08-01
PCT/EP2007/054444 WO2007128817A2 (en) 2006-05-09 2007-05-08 Insulin derivative

Publications (1)

Publication Number Publication Date
IL194312D0 true IL194312D0 (en) 2011-08-01

Family

ID=38668119

Family Applications (1)

Application Number Title Priority Date Filing Date
IL19431208A IL194312D0 (en) 2006-05-09 2008-09-24 Insulin derivative

Country Status (13)

Country Link
US (1) US8933021B2 (en)
EP (2) EP2386572B1 (en)
JP (1) JP5269767B2 (en)
KR (1) KR101441444B1 (en)
AU (1) AU2007247109B2 (en)
BR (1) BRPI0712041A2 (en)
CA (1) CA2649235A1 (en)
ES (2) ES2548393T3 (en)
IL (1) IL194312D0 (en)
MX (1) MX2008014061A (en)
NO (1) NO20085056A (en)
RU (1) RU2451029C2 (en)
WO (1) WO2007128817A2 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0413276A (en) * 2003-08-05 2006-10-10 Novo Nordisk As insulin derivative, zinc complex thereof, pharmaceutical composition and method for treating diabetes in a patient
WO2006082205A1 (en) 2005-02-02 2006-08-10 Novo Nordisk A/S Insulin derivatives
JP4933455B2 (en) 2005-02-02 2012-05-16 ノヴォ ノルディスク アー/エス New insulin derivative
AT519780T (en) * 2005-12-28 2011-08-15 Novo Nordisk As An acylated insulin and zinc-containing compositions and methods for preparing these compositions
JP5202338B2 (en) 2006-02-27 2013-06-05 ノボ・ノルデイスク・エー/エス New insulin derivatives
ES2553154T3 (en) 2006-05-09 2015-12-04 Novo Nordisk A/S Insulin derivative
KR101729986B1 (en) 2006-09-22 2017-04-25 노보 노르디스크 에이/에스 Protease resistant insulin analogues
US10100098B2 (en) 2006-12-13 2018-10-16 Stelis Biopharma Private Limited Insulin production methods and proinsulin constructs
WO2008132224A2 (en) 2007-04-30 2008-11-06 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
JP5552046B2 (en) 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー/エス Pharmaceutical formulation comprising insulin derivative
EP2025674A1 (en) 2007-08-15 2009-02-18 sanofi-aventis Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs
EP2217621B1 (en) 2007-11-08 2015-04-22 Novo Nordisk A/S Insulin derivative
ES2612736T3 (en) 2007-11-16 2017-05-18 Novo Nordisk A/S Stable pharmaceutical compositions comprising liraglutide and degludec
JP5762001B2 (en) 2008-03-14 2015-08-12 ノボ・ノルデイスク・エー/エス Protease stabilized insulin analogue
EP2910571B1 (en) 2008-03-18 2016-10-05 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
CN102202683A (en) * 2008-10-30 2011-09-28 诺沃-诺迪斯克有限公司 Treating diabetes melitus using insulin injections with less than daily injection frequency
MX2012006634A (en) 2009-12-16 2012-06-21 Novo Nordisk As Double-acylated glp-1 derivatives.
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
DE102010015123A1 (en) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh New benzylamidic diphenylazetidinone compounds, useful for treating lipid disorders, hyperlipidemia, atherosclerotic manifestations or insulin resistance, and for reducing serum cholesterol levels
WO2011157827A1 (en) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
AU2011322495A1 (en) * 2010-10-27 2013-04-11 Novo Nordisk A/S Treating diabetes melitus using insulin injections administered with varying injection intervals
BR112013019508A2 (en) * 2011-02-01 2016-08-30 Novo Nordisk As Purification of insulin
US20120214963A1 (en) * 2011-02-23 2012-08-23 Elona Biotechnologies Aspart proinsulin compositions and methods of producing aspart insulin analogs therefrom
EP2683699B1 (en) 2011-03-08 2015-06-24 Sanofi Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683705B1 (en) 2011-03-08 2015-04-22 Sanofi Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120053A1 (en) 2011-03-08 2012-09-13 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
CN106117344A (en) 2011-04-12 2016-11-16 诺沃—诺迪斯克有限公司 Double-acylated glp-1 derivatives
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
JP6262206B2 (en) 2012-05-01 2018-01-17 ノヴォ ノルディスク アー/エス Pharmaceutical compositions
US9457096B2 (en) 2012-07-06 2016-10-04 Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Concet) Protozoan variant-specific surface proteins (VSP) as carriers for oral drug delivery
WO2014177623A1 (en) 2013-04-30 2014-11-06 Novo Nordisk A/S Novel administration regime
RS57004B1 (en) 2013-10-07 2018-05-31 Novo Nordisk As Novel derivative of an insulin analogue
AR099569A1 (en) 2014-02-28 2016-08-03 Novo Nordisk As Insulin derivatives and medical uses of these

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3528960A (en) * 1968-10-07 1970-09-15 Lilly Co Eli N-carboxyaroyl insulins
US4683202B1 (en) 1985-03-28 1990-11-27 Cetus Corp
PH25772A (en) 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
NZ222907A (en) 1986-12-16 1990-08-28 Novo Industri As Preparation for intranasal administration containing a phospholipid absorption enhancing system
JPH01254699A (en) 1988-04-05 1989-10-11 Kodama Kk Insulin derivative and use thereof
AU641631B2 (en) 1988-12-23 1993-09-30 Novo Nordisk A/S Human insulin analogues
NZ232375A (en) 1989-02-09 1992-04-28 Lilly Co Eli Insulin analogues modified at b29
JP3018463B2 (en) 1989-10-19 2000-03-13 日本油脂株式会社 Glucose-responsive drug release complex
DK10191D0 (en) * 1991-01-22 1991-01-22 Novo Nordisk As Novel peptides
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
US6011007A (en) 1993-09-17 2000-01-04 Novo Nordisk A/S Acylated insulin
DE122004000035I2 (en) * 1993-09-17 2009-08-06 Novo Nordisk As acylated insulin
US6869930B1 (en) 1993-09-17 2005-03-22 Novo Nordisk A/S Acylated insulin
US5693609A (en) 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
MX9707056A (en) * 1995-03-17 1997-11-29 Novo Nordisk As Insulin derivatives.
US6451970B1 (en) * 1996-02-21 2002-09-17 Novo Nordisk A/S Peptide derivatives
ES2230607T3 (en) * 1996-07-11 2005-05-01 Novo Nordisk A/S Selective acylation method.
US5905140A (en) 1996-07-11 1999-05-18 Novo Nordisk A/S, Novo Alle Selective acylation method
US5898067A (en) 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
ZA9809744B (en) 1997-10-31 2000-04-26 Lilly Co Eli Method for administering acylated insulin.
EP1044016B1 (en) 1998-01-09 2005-03-16 Novo Nordisk A/S Stabilised insulin compositions
JP2004537580A (en) 2001-08-10 2004-12-16 エピックス メディカル, インコーポレイテッド Polypeptide conjugates with prolonged circulating half-life
US8003605B2 (en) 2002-03-13 2011-08-23 Novo Nordisk A/S Minimising body weight gain in insulin treatment
US20040138099A1 (en) 2002-11-29 2004-07-15 Draeger Eberhard Kurt Insulin administration regimens for the treatment of subjects with diabetes
EP1644411A2 (en) * 2003-07-11 2006-04-12 Novo Nordisk A/S Stabilised insulin compositions
DE602004021603D1 (en) * 2003-07-25 2009-07-30 Conjuchem Biotechnologies Inc Insulinderivative with long-lasting effect and process for their preparation
BRPI0413276A (en) 2003-08-05 2006-10-10 Novo Nordisk As insulin derivative, zinc complex thereof, pharmaceutical composition and method for treating diabetes in a patient
CA2546243A1 (en) 2003-11-14 2005-05-26 University Of Tennessee Research Corporation The mycolactone locus : an assembly line for producing novel polyketides, with therapeutic and prophylatic uses
JP2007532096A (en) 2003-11-14 2007-11-15 ノボ ノルディスク アクティーゼルスカブNovo Nordisk Aktie Selsxab Method for producing acylated insulin
US20070221884A1 (en) 2004-07-16 2007-09-27 Holger Hoppe Liminescent Silicon Oxide Flakes
WO2006008238A1 (en) 2004-07-16 2006-01-26 Novo Nordisk A/S Method for selective acylation
WO2006082205A1 (en) * 2005-02-02 2006-08-10 Novo Nordisk A/S Insulin derivatives
JP4933455B2 (en) 2005-02-02 2012-05-16 ノヴォ ノルディスク アー/エス New insulin derivative
DE102005062618B4 (en) 2005-12-23 2008-05-08 Carl Zeiss Smt Ag Optical imaging device and imaging method with determination of imaging errors
AT519780T (en) * 2005-12-28 2011-08-15 Novo Nordisk As An acylated insulin and zinc-containing compositions and methods for preparing these compositions
JP5202338B2 (en) 2006-02-27 2013-06-05 ノボ・ノルデイスク・エー/エス New insulin derivatives
JP2009530242A (en) 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー/エス Acylated single-chain insulin
ES2553154T3 (en) 2006-05-09 2015-12-04 Novo Nordisk A/S Insulin derivative
JP5552046B2 (en) 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー/エス Pharmaceutical formulation comprising insulin derivative
EP2217621B1 (en) 2007-11-08 2015-04-22 Novo Nordisk A/S Insulin derivative
EP2207610B1 (en) 2007-11-09 2017-04-05 Mann + Hummel GmbH Liquid filter
CN102202683A (en) 2008-10-30 2011-09-28 诺沃-诺迪斯克有限公司 Treating diabetes melitus using insulin injections with less than daily injection frequency
ES2612468T3 (en) 2010-05-10 2017-05-17 Novo Nordisk A/S Process for the preparation of insulin-zinc complexes
CN103025806B (en) 2010-05-10 2015-06-10 巴斯夫欧洲公司 Thermoplastic polyurethane comprising glycerol, esterified with at least one aliphatic carboxylic acid, as plasticizer

Also Published As

Publication number Publication date
KR101441444B1 (en) 2014-09-18
BRPI0712041A2 (en) 2011-12-27
ES2548393T3 (en) 2015-10-16
EP2386572A1 (en) 2011-11-16
US8933021B2 (en) 2015-01-13
RU2451029C2 (en) 2012-05-20
US20090239785A1 (en) 2009-09-24
WO2007128817A2 (en) 2007-11-15
AU2007247109B2 (en) 2012-03-15
JP2009536179A (en) 2009-10-08
RU2008143668A (en) 2010-06-20
EP2015770B1 (en) 2012-09-26
WO2007128817A3 (en) 2008-03-06
KR20090018906A (en) 2009-02-24
AU2007247109A1 (en) 2007-11-15
EP2386572B1 (en) 2015-07-08
JP5269767B2 (en) 2013-08-21
MX2008014061A (en) 2008-11-14
EP2015770A2 (en) 2009-01-21
CA2649235A1 (en) 2007-11-15
NO20085056A (en) 2008-12-03
ES2395738T3 (en) 2013-02-14

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