IL165777A0 - APO/2 ligand/trail variants and uses thereof - Google Patents

APO/2 ligand/trail variants and uses thereof

Info

Publication number
IL165777A0
IL165777A0 IL16577704A IL16577704A IL165777A0 IL 165777 A0 IL165777 A0 IL 165777A0 IL 16577704 A IL16577704 A IL 16577704A IL 16577704 A IL16577704 A IL 16577704A IL 165777 A0 IL165777 A0 IL 165777A0
Authority
IL
Israel
Prior art keywords
apo
ligand
trail variants
trail
variants
Prior art date
Application number
IL16577704A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL165777A0 publication Critical patent/IL165777A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
IL16577704A 2002-06-24 2004-12-15 APO/2 ligand/trail variants and uses thereof IL165777A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39105002P 2002-06-24 2002-06-24
PCT/US2003/019750 WO2004001009A2 (fr) 2002-06-24 2003-06-23 Variants du ligand apo-2/trail et utilisations de ceux-ci

Publications (1)

Publication Number Publication Date
IL165777A0 true IL165777A0 (en) 2006-01-15

Family

ID=30000661

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16577704A IL165777A0 (en) 2002-06-24 2004-12-15 APO/2 ligand/trail variants and uses thereof

Country Status (7)

Country Link
US (4) US20060141561A1 (fr)
EP (2) EP2500032A1 (fr)
JP (2) JP4574350B2 (fr)
AU (2) AU2003247609A1 (fr)
CA (1) CA2489348A1 (fr)
IL (1) IL165777A0 (fr)
WO (1) WO2004001009A2 (fr)

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CA2867631C (fr) 2012-03-28 2019-06-11 Amgen Inc. Combinaisons d'agonistes des recepteurs dr5
CR20160132A (es) 2013-08-12 2016-08-25 Genentech Inc Composiciones y método para tratar condiciones asociadas con el complemento
WO2015138638A1 (fr) 2014-03-11 2015-09-17 Theraly Pharmaceuticals, Inc. Agonistes de récepteur de protéine trail à action prolongée pour le traitement de maladies auto-immunes
CA2944712A1 (fr) 2014-05-01 2015-11-05 Genentech, Inc. Variants d'anticorps anti-facteur d et leurs utilisations
KR20150133576A (ko) * 2014-05-20 2015-11-30 삼성전자주식회사 화학적 개질된 표적화 단백질 및 그의 이용
JP2018534930A (ja) 2015-10-30 2018-11-29 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体及びコンジュゲート
CN108472382A (zh) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 抗-因子d抗体变体缀合物及其用途
US11007251B2 (en) 2015-12-17 2021-05-18 The Johns Hopkins University Ameliorating systemic sclerosis with death receptor agonists
CA3020339C (fr) 2016-04-07 2022-05-03 The Johns Hopkins University Compositions et procedes de traitement de la pancreatite et de la douleur avec des agonistes du recepteur de mort
IT201900024622A1 (it) 2019-12-18 2021-06-18 Univ Degli Studi G Dannunzio Chieti Pescara Pegilazione innovativa del killer tnf-apoptosis induced ligand (killer-trail)

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CA2489348A1 (fr) 2003-12-31
US20120165267A1 (en) 2012-06-28
JP2010065037A (ja) 2010-03-25
US20060141561A1 (en) 2006-06-29
EP2500032A1 (fr) 2012-09-19
JP4574350B2 (ja) 2010-11-04
US20130165383A1 (en) 2013-06-27
JP2006508640A (ja) 2006-03-16
AU2003247609A1 (en) 2004-01-06
WO2004001009A3 (fr) 2004-10-28
US20070098681A1 (en) 2007-05-03
EP2500032A9 (fr) 2013-04-17
EP1556076A2 (fr) 2005-07-27
EP1556076A4 (fr) 2009-07-08
WO2004001009A2 (fr) 2003-12-31
AU2009212834A1 (en) 2009-09-24

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