IL161908D0 - Quinazoline derivatives for the treatment of abnormal cell growth - Google Patents

Quinazoline derivatives for the treatment of abnormal cell growth

Info

Publication number
IL161908D0
IL161908D0 IL16190802A IL16190802A IL161908D0 IL 161908 D0 IL161908 D0 IL 161908D0 IL 16190802 A IL16190802 A IL 16190802A IL 16190802 A IL16190802 A IL 16190802A IL 161908 D0 IL161908 D0 IL 161908D0
Authority
IL
Israel
Prior art keywords
treatment
cell growth
abnormal cell
quinazoline derivatives
quinazoline
Prior art date
Application number
IL16190802A
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US34109101P priority Critical
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Priority to PCT/IB2002/004636 priority patent/WO2003049740A1/en
Publication of IL161908D0 publication Critical patent/IL161908D0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
IL16190802A 2001-12-12 2002-11-04 Quinazoline derivatives for the treatment of abnormal cell growth IL161908D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US34109101P true 2001-12-12 2001-12-12
PCT/IB2002/004636 WO2003049740A1 (en) 2001-12-12 2002-11-04 Quinazoline derivatives for the treatment of abnormal cell growth

Publications (1)

Publication Number Publication Date
IL161908D0 true IL161908D0 (en) 2005-11-20

Family

ID=23336198

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16190802A IL161908D0 (en) 2001-12-12 2002-11-04 Quinazoline derivatives for the treatment of abnormal cell growth

Country Status (29)

Country Link
US (1) US20030171386A1 (en)
EP (1) EP1465632A1 (en)
JP (1) JP4181502B2 (en)
KR (1) KR20040063948A (en)
CN (1) CN1602195A (en)
AP (1) AP200403058A0 (en)
AR (1) AR037771A1 (en)
AU (1) AU2002339687A1 (en)
BR (1) BR0214499A (en)
CA (1) CA2469670A1 (en)
DO (1) DOP2002000545A (en)
EA (1) EA200400680A1 (en)
EC (1) ECSP045146A (en)
GT (1) GT200200273A (en)
HR (1) HRP20040529A2 (en)
HU (1) HU0501069A2 (en)
IL (1) IL161908D0 (en)
IS (1) IS7233A (en)
MA (1) MA27154A1 (en)
MX (1) MXPA04004107A (en)
NO (1) NO20042882L (en)
OA (1) OA12734A (en)
PA (1) PA8561301A1 (en)
PE (1) PE07602003A1 (en)
PL (1) PL373848A1 (en)
TN (1) TNSN04111A1 (en)
TW (1) TW200301121A (en)
WO (1) WO2003049740A1 (en)
ZA (1) ZA200404264B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1521747B1 (en) 2002-07-15 2018-09-05 Symphony Evolution, Inc. Receptor-type kinase modulators and methods of use
EP1575592A1 (en) * 2002-12-18 2005-09-21 Pfizer Products Inc. 4-anilino quinazoline derivatives for the treatment of abnormal cell growth
PL377533A1 (en) * 2002-12-19 2006-02-06 Pfizer Products Inc. Complexes of e-2-methoxy-n-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide, their method of production, and use
WO2005016347A1 (en) * 2003-08-18 2005-02-24 Pfizer Products Inc. Dosing schedule for erbb2 anticancer agents
PT2210607E (en) * 2003-09-26 2012-01-31 Exelixis Inc N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-n`-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer
BRPI0417213A (en) * 2003-12-24 2007-02-06 Scios Inc treating malignant gliomas with inhibitors of TGFbeta
AP2204A (en) * 2004-05-06 2011-02-07 Warner Lambert Co 4-phenylamino-quinazolin-6-yl-amides.
GB0417107D0 (en) * 2004-07-30 2004-09-01 Wellcome Trust The Genes II
EP1896451A2 (en) * 2005-06-03 2008-03-12 Pfizer Products Incorporated Bicyclic derivatives for the treatment of abnormal cell growth
KR20090090336A (en) 2006-12-12 2009-08-25 다케다 야쿠힌 고교 가부시키가이샤 Fused heterocyclic compound
MX2010008621A (en) 2008-02-07 2010-09-24 Boehringer Ingelheim Int Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production.
AR070874A1 (en) 2008-03-12 2010-05-12 Takeda Pharmaceutical Fused heterocyclic compound, a pharmaceutical composition comprising it and its use in cancer treatment.
US8088782B2 (en) 2008-05-13 2012-01-03 Astrazeneca Ab Crystalline 4-(3-chloro-2-fluoroanilino)-7 methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate form A
EP2313397B1 (en) 2008-08-08 2016-04-20 Boehringer Ingelheim International GmbH Cyclohexyloxy substituted heterocycles, medicine containing these connections, their application and production method
NZ618004A (en) 2009-01-16 2015-06-26 Exelixis Inc Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
WO2011153050A1 (en) 2010-06-02 2011-12-08 The Trustees Of The University Of Pennsylvania Methods and use of compounds that bind to her2/neu receptor complex
US8993634B2 (en) 2010-06-02 2015-03-31 The Trustees Of The University Of Pennsylvania Methods and use of compounds that bind to Her2/neu receptor complex
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
SG2014011316A (en) 2011-08-31 2014-06-27 Genentech Inc Diagnostic markers
KR101589632B1 (en) 2014-06-03 2016-02-01 한국과학기술연구원 6-Benzyloxyquinazolin-7-ylurea derivatives with an anticancer activity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721237A (en) * 1991-05-10 1998-02-24 Rhone-Poulenc Rorer Pharmaceuticals Inc. Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
IL112249A (en) * 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
GB9603095D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
ZA9806729B (en) * 1997-07-29 1999-02-02 Warner Lambert Co Irreversible inhibitors of tyrosine kinases
ZA9806732B (en) * 1997-07-29 1999-02-02 Warner Lambert Co Irreversible inhibitiors of tyrosine kinases
TW519541B (en) * 1999-01-27 2003-02-01 Pfizer Prod Inc Substituted bicyclic derivatives useful as anticancer agents
JP3270834B2 (en) * 1999-01-27 2002-04-02 ファイザー・プロダクツ・インク Useful heteroaromatic bicyclic derivatives as anticancer agents
JP2003504363A (en) * 1999-07-09 2003-02-04 グラクソ グループ リミテッド Anilinoquinazoline such as protein tyrosine kinase inhibitors
IL148891D0 (en) * 1999-10-19 2002-09-12 Merck & Co Inc Tyrosine kinase inhibitors
DE60108754T2 (en) * 2000-06-22 2005-06-23 Pfizer Products Inc., Groton Substituted bicyclic derivatives for the treatment of abnormal cell growth
UA75482C2 (en) * 2001-12-12 2004-09-15 Pfizer Prod Inc Salts of e-2-methoxy-n-(3-{4-[3-methyl-4-(6-methylpyridine-3-yloxy)phenylamino]quinozaline -6-yl}alyl)acetamide, a method for the preparation and use thereof for the treatment of cancer

Also Published As

Publication number Publication date
TNSN04111A1 (en) 2006-06-01
PE07602003A1 (en) 2003-09-05
HU0501069A2 (en) 2006-06-28
DOP2002000545A (en) 2003-06-16
OA12734A (en) 2006-06-28
NO20042882L (en) 2004-07-07
US20030171386A1 (en) 2003-09-11
CA2469670A1 (en) 2003-06-19
PA8561301A1 (en) 2003-12-30
AU2002339687A1 (en) 2003-06-23
ZA200404264B (en) 2005-08-31
MA27154A1 (en) 2005-01-03
ECSP045146A (en) 2004-07-23
JP4181502B2 (en) 2008-11-19
PL373848A1 (en) 2005-09-19
GT200200273A (en) 2003-10-03
BR0214499A (en) 2005-05-10
CN1602195A (en) 2005-03-30
WO2003049740A1 (en) 2003-06-19
AR037771A1 (en) 2004-12-01
EP1465632A1 (en) 2004-10-13
AP200403058A0 (en) 2004-06-30
EA200400680A1 (en) 2005-06-30
KR20040063948A (en) 2004-07-14
HRP20040529A2 (en) 2004-10-31
IS7233A (en) 2004-04-26
MXPA04004107A (en) 2004-07-23
JP2005527486A (en) 2005-09-15
TW200301121A (en) 2003-07-01

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