IL161452A0 - Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses - Google Patents
Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responsesInfo
- Publication number
- IL161452A0 IL161452A0 IL16145202A IL16145202A IL161452A0 IL 161452 A0 IL161452 A0 IL 161452A0 IL 16145202 A IL16145202 A IL 16145202A IL 16145202 A IL16145202 A IL 16145202A IL 161452 A0 IL161452 A0 IL 161452A0
- Authority
- IL
- Israel
- Prior art keywords
- synaptic responses
- glutamatergic synaptic
- carbonylbenzoxazine
- compounds
- enhancing glutamatergic
- Prior art date
Links
- FEFCQDINBPEMNU-UHFFFAOYSA-N 4h-1,2-benzoxazin-3-ylidenemethanone Chemical class C1=CC=C2ONC(=C=O)CC2=C1 FEFCQDINBPEMNU-UHFFFAOYSA-N 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 230000000848 glutamatergic effect Effects 0.000 title 1
- 230000009782 synaptic response Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33333401P | 2001-11-26 | 2001-11-26 | |
| PCT/US2002/037646 WO2003045315A2 (en) | 2001-11-26 | 2002-11-25 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL161452A0 true IL161452A0 (en) | 2004-09-27 |
Family
ID=23302344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16145202A IL161452A0 (en) | 2001-11-26 | 2002-11-25 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7799913B2 (es) |
| EP (1) | EP1448537A4 (es) |
| JP (1) | JP4620349B2 (es) |
| KR (1) | KR100915176B1 (es) |
| CN (1) | CN1620440A (es) |
| AU (1) | AU2002352886B2 (es) |
| BR (1) | BR0214425A (es) |
| CA (1) | CA2463592A1 (es) |
| CZ (1) | CZ2004632A3 (es) |
| EA (1) | EA011034B1 (es) |
| GE (1) | GEP20063859B (es) |
| HR (1) | HRP20040424A2 (es) |
| HU (1) | HUP0402279A3 (es) |
| IL (1) | IL161452A0 (es) |
| MA (1) | MA26233A1 (es) |
| MX (1) | MXPA04004815A (es) |
| NO (1) | NO20041590L (es) |
| NZ (1) | NZ532368A (es) |
| PL (1) | PL371722A1 (es) |
| SK (1) | SK2292004A3 (es) |
| UA (1) | UA79940C2 (es) |
| WO (1) | WO2003045315A2 (es) |
| ZA (1) | ZA200403729B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2144506E (pt) * | 2007-01-03 | 2011-12-21 | Servier Lab | Composto de [1,2,3]-benzotriazinona substituída em posição 3 para aumentar as respostas glutamatérgicas nas sinapses |
| EA200900937A1 (ru) * | 2007-01-03 | 2009-12-30 | Кортекс Фармасеутикалс, Инк. | Соединения 3-замещенного-[1,2,3]бензотриазинона для усиления глутаматергических синаптических ответов |
| US20130058915A1 (en) | 2010-03-02 | 2013-03-07 | Children's Medica Center Corporation | Methods and compositions for treatment of angelman syndrome and autism spectrum disorders |
| CA2837883C (en) * | 2011-06-08 | 2019-10-29 | Sunovion Pharmaceuticals, Inc. | Metabotropic glutamate receptor 5 modulators and methods of use thereof |
| MX2015017253A (es) | 2013-06-13 | 2016-04-19 | Veroscience Llc | Composiciones y metodos para tratar trastornos metabolicos. |
| CA2988572A1 (en) | 2015-06-26 | 2016-12-29 | Takeda Pharmaceutical Company Limited | 2,3-dihydro-4h-1,3-benzoxazin-4-one derivatives as modulators of cholinergic muscarinic m1 receptor |
| WO2017069173A1 (ja) | 2015-10-20 | 2017-04-27 | 武田薬品工業株式会社 | 複素環化合物 |
| BR112020002674A2 (pt) | 2017-08-07 | 2020-07-28 | Joint Stock Company Biocad | compostos heterocíclicos inovadores como inibidores de cdk8/19 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2943087A (en) * | 1960-06-28 | n naoh | ||
| DE1122531B (de) * | 1957-09-13 | 1962-01-25 | Thomae Gmbh Dr K | Verfahren zur Herstellung von therapeutisch wertvollen 4-Oxo-2-(halogenalkyl)-2,3-dihydro-benzoxazinen-(1,3) |
| US4022139A (en) * | 1975-10-28 | 1977-05-10 | Blue Bell, Inc. | Tacker guide and method |
| EP0010348A1 (en) * | 1978-09-12 | 1980-04-30 | Imperial Chemical Industries Plc | Heterocyclic trichloromethyl derivatives, process for their preparation and their use |
| JPH0597824A (ja) * | 1990-09-25 | 1993-04-20 | Takeda Chem Ind Ltd | １，３−ベンゾオキサジン誘導体 |
| DE69331761T2 (de) * | 1992-07-24 | 2002-09-12 | The Regents Of The University Of California, Oakland | Arzneimittel, die den durch ampa rezeptoren vermittelten synaptischen respons erhöhen |
| US5650409A (en) * | 1995-06-02 | 1997-07-22 | Cortex Pharmaceuticals, Inc. | Benzoyl piperidines/pyrrolidines for enhancing synaptic response |
| US5736543A (en) * | 1996-04-03 | 1998-04-07 | The Regents Of The University Of California | Benzoxazines for enhancing synaptic response |
| GB9716962D0 (en) * | 1997-08-12 | 1997-10-15 | Univ Birmingham | Liver function test |
| AU1198699A (en) * | 1997-10-27 | 1999-04-23 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them |
| HUP0101280A3 (en) * | 1998-02-18 | 2003-02-28 | Neurosearch As | Positive ampa receptor modulator compounds and their use |
| US6124278A (en) * | 1998-04-03 | 2000-09-26 | The Regents Of The University Of California | Acylbenzoxazines for enhancing synaptic response |
-
2002
- 2002-11-25 HU HU0402279A patent/HUP0402279A3/hu unknown
- 2002-11-25 US US10/495,049 patent/US7799913B2/en not_active Expired - Fee Related
- 2002-11-25 MX MXPA04004815A patent/MXPA04004815A/es active IP Right Grant
- 2002-11-25 CA CA002463592A patent/CA2463592A1/en not_active Abandoned
- 2002-11-25 GE GE5593A patent/GEP20063859B/en unknown
- 2002-11-25 PL PL02371722A patent/PL371722A1/xx not_active Application Discontinuation
- 2002-11-25 EP EP02789846A patent/EP1448537A4/en not_active Withdrawn
- 2002-11-25 CN CNA028234502A patent/CN1620440A/zh active Pending
- 2002-11-25 UA UA20040503965A patent/UA79940C2/uk unknown
- 2002-11-25 CZ CZ2004632A patent/CZ2004632A3/cs unknown
- 2002-11-25 KR KR1020047007502A patent/KR100915176B1/ko not_active IP Right Cessation
- 2002-11-25 IL IL16145202A patent/IL161452A0/xx unknown
- 2002-11-25 EA EA200400584A patent/EA011034B1/ru not_active IP Right Cessation
- 2002-11-25 NZ NZ532368A patent/NZ532368A/en not_active IP Right Cessation
- 2002-11-25 JP JP2003546820A patent/JP4620349B2/ja not_active Expired - Fee Related
- 2002-11-25 SK SK229-2004A patent/SK2292004A3/sk not_active Application Discontinuation
- 2002-11-25 WO PCT/US2002/037646 patent/WO2003045315A2/en active Application Filing
- 2002-11-25 BR BR0214425-5A patent/BR0214425A/pt not_active Application Discontinuation
- 2002-11-25 AU AU2002352886A patent/AU2002352886B2/en not_active Ceased
-
2004
- 2004-04-19 NO NO20041590A patent/NO20041590L/no not_active Application Discontinuation
- 2004-05-12 HR HR20040424A patent/HRP20040424A2/xx not_active Application Discontinuation
- 2004-05-14 ZA ZA200403729A patent/ZA200403729B/en unknown
- 2004-05-21 MA MA27691A patent/MA26233A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1448537A2 (en) | 2004-08-25 |
| WO2003045315A3 (en) | 2003-08-28 |
| EA200400584A1 (ru) | 2005-02-24 |
| JP2005510532A (ja) | 2005-04-21 |
| KR20040054777A (ko) | 2004-06-25 |
| CA2463592A1 (en) | 2003-06-05 |
| US7799913B2 (en) | 2010-09-21 |
| CN1620440A (zh) | 2005-05-25 |
| NZ532368A (en) | 2006-10-27 |
| CZ2004632A3 (cs) | 2004-08-18 |
| WO2003045315A2 (en) | 2003-06-05 |
| UA79940C2 (en) | 2007-08-10 |
| SK2292004A3 (en) | 2004-09-08 |
| ZA200403729B (en) | 2005-05-19 |
| PL371722A1 (en) | 2005-06-27 |
| EP1448537A4 (en) | 2005-05-04 |
| MA26233A1 (fr) | 2004-07-01 |
| AU2002352886B2 (en) | 2008-10-16 |
| JP4620349B2 (ja) | 2011-01-26 |
| MXPA04004815A (es) | 2005-02-17 |
| NO20041590L (no) | 2004-07-12 |
| EA011034B1 (ru) | 2008-12-30 |
| GEP20063859B (en) | 2006-06-26 |
| US20040259871A1 (en) | 2004-12-23 |
| HRP20040424A2 (en) | 2005-06-30 |
| HUP0402279A3 (en) | 2008-09-29 |
| HUP0402279A2 (hu) | 2005-02-28 |
| AU2002352886A1 (en) | 2003-06-10 |
| KR100915176B1 (ko) | 2009-09-03 |
| BR0214425A (pt) | 2004-11-03 |
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