IL161325A0 - Substituted benzopyrans as selective estrogen receptor-beta agonists - Google Patents
Substituted benzopyrans as selective estrogen receptor-beta agonistsInfo
- Publication number
- IL161325A0 IL161325A0 IL16132502A IL16132502A IL161325A0 IL 161325 A0 IL161325 A0 IL 161325A0 IL 16132502 A IL16132502 A IL 16132502A IL 16132502 A IL16132502 A IL 16132502A IL 161325 A0 IL161325 A0 IL 161325A0
- Authority
- IL
- Israel
- Prior art keywords
- estrogen receptor
- selective estrogen
- beta agonists
- agonists
- substituted benzopyrans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33276601P | 2001-11-19 | 2001-11-19 | |
US36362202P | 2002-03-11 | 2002-03-11 | |
PCT/US2002/033622 WO2003044006A1 (en) | 2001-11-19 | 2002-11-07 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
IL161325A0 true IL161325A0 (en) | 2004-09-27 |
Family
ID=26988373
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16132502A IL161325A0 (en) | 2001-11-19 | 2002-11-07 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
IL161325A IL161325A (en) | 2001-11-19 | 2004-04-08 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
IL185867A IL185867A (en) | 2001-11-19 | 2007-09-10 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL161325A IL161325A (en) | 2001-11-19 | 2004-04-08 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
IL185867A IL185867A (en) | 2001-11-19 | 2007-09-10 | Substituted benzopyrans as selective estrogen receptor-beta agonists |
Country Status (24)
Country | Link |
---|---|
US (1) | US7217734B2 (no) |
EP (1) | EP1448544B1 (no) |
JP (1) | JP4381810B2 (no) |
KR (1) | KR100950616B1 (no) |
CN (1) | CN1312147C (no) |
AT (1) | ATE362471T1 (no) |
AU (1) | AU2002359283B2 (no) |
CA (1) | CA2467013C (no) |
CY (1) | CY1106726T1 (no) |
DE (1) | DE60220179T2 (no) |
DK (1) | DK1448544T3 (no) |
EA (1) | EA007382B1 (no) |
EC (1) | ECSP045113A (no) |
ES (1) | ES2286322T3 (no) |
HK (1) | HK1068349A1 (no) |
HR (1) | HRP20040439A2 (no) |
HU (1) | HU229351B1 (no) |
IL (3) | IL161325A0 (no) |
MX (1) | MXPA04004703A (no) |
NO (1) | NO328563B1 (no) |
NZ (1) | NZ531850A (no) |
PL (1) | PL205733B1 (no) |
PT (1) | PT1448544E (no) |
WO (1) | WO2003044006A1 (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1618102B1 (en) * | 2003-04-21 | 2010-02-10 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor-beta agonists |
AU2004232798B2 (en) * | 2003-04-21 | 2010-04-22 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor-beta agonists |
CA2578164A1 (en) | 2004-09-07 | 2006-03-16 | Wyeth | 6h-[1]benzopyrano[4,3-b]quinolines and their use as estrogenic agents |
ES2361031T3 (es) * | 2004-10-18 | 2011-06-13 | Eli Lilly And Company | Benzopiranos sustituidos como agonistas selectivos del receptor beta de estrógenos. |
AU2005307704A1 (en) * | 2004-11-18 | 2006-05-26 | Janssen Pharmaceutica N.V. | Novel 2H-chromene derivatives as selective estrogen receptor modulators |
US8093302B2 (en) | 2005-02-15 | 2012-01-10 | Eli Lilly And Company | Substituted tetralins as selective estrogen receptor-β agonists |
US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
US8063102B2 (en) | 2009-03-13 | 2011-11-22 | N.V. Organon | Tetrahydronaphthalen-2-ol derivatives |
TW201043595A (en) | 2009-03-13 | 2010-12-16 | Organon Nv | Tetrahydronaphthalen-2-ol derivatives |
CA2932224A1 (en) | 2013-12-05 | 2015-06-11 | Karo Pharma Ab | Estrogen receptor beta agonists for use in treating mesothelioma |
AU2016324495B2 (en) | 2015-09-17 | 2020-12-03 | Institute Of Molecular Genetics As Cr, V.V.I. | Carborane compounds and methods of use thereof |
US20230114408A1 (en) * | 2020-03-11 | 2023-04-13 | Ohio State Innovation Foundation | Methods of modulating t-cell activation using estrogen receptor beta (erb) agonists |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3901926A (en) * | 1973-04-02 | 1975-08-26 | Abbott Lab | Alkylphenyl benzopyrans |
WO1997009348A2 (en) | 1995-09-08 | 1997-03-13 | Karo Bio Ab | Orphan receptor |
WO1999002512A1 (en) * | 1997-07-09 | 1999-01-21 | Novo Nordisk A/S | Dl-2,3-diaryl-2h-1-benzopyrans |
WO2000055137A1 (en) | 1999-03-17 | 2000-09-21 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
US6593322B1 (en) | 1999-03-17 | 2003-07-15 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
TR200201762T2 (tr) | 1999-04-16 | 2002-10-21 | Astrazeneca Ab | B östrojen reseptörü ligandları. |
CA2396059A1 (en) | 1999-12-30 | 2001-07-12 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
AU2001256164A1 (en) * | 2000-03-01 | 2001-09-12 | Akzo Nobel N.V. | Chroman derivatives as estrogenic compounds |
US6686371B2 (en) | 2000-03-27 | 2004-02-03 | Akzo Nobel N.V. | Non-steroidal, tetracylic compounds for estrogen-related treatments |
GB2361642A (en) | 2000-10-24 | 2001-10-31 | Karobio Ab | Estrogen receptor beta (ERbeta) agonists for use in cancer treatment |
UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
TWI306450B (en) | 2001-12-13 | 2009-02-21 | Wyeth Corp | Substituted phenyl naphthalenes as estrogenic agents |
US6630508B1 (en) * | 2002-02-11 | 2003-10-07 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor β agonists |
-
2002
- 2002-11-07 KR KR1020047007563A patent/KR100950616B1/ko not_active IP Right Cessation
- 2002-11-07 CA CA2467013A patent/CA2467013C/en not_active Expired - Fee Related
- 2002-11-07 US US10/493,092 patent/US7217734B2/en not_active Expired - Fee Related
- 2002-11-07 PT PT02793806T patent/PT1448544E/pt unknown
- 2002-11-07 IL IL16132502A patent/IL161325A0/xx unknown
- 2002-11-07 PL PL374510A patent/PL205733B1/pl unknown
- 2002-11-07 NZ NZ531850A patent/NZ531850A/en not_active IP Right Cessation
- 2002-11-07 CN CNB028229916A patent/CN1312147C/zh not_active Expired - Fee Related
- 2002-11-07 ES ES02793806T patent/ES2286322T3/es not_active Expired - Lifetime
- 2002-11-07 EP EP02793806A patent/EP1448544B1/en not_active Expired - Lifetime
- 2002-11-07 AT AT02793806T patent/ATE362471T1/de active
- 2002-11-07 WO PCT/US2002/033622 patent/WO2003044006A1/en active IP Right Grant
- 2002-11-07 EA EA200400695A patent/EA007382B1/ru not_active IP Right Cessation
- 2002-11-07 JP JP2003545643A patent/JP4381810B2/ja not_active Expired - Fee Related
- 2002-11-07 HU HU0402628A patent/HU229351B1/hu not_active IP Right Cessation
- 2002-11-07 AU AU2002359283A patent/AU2002359283B2/en not_active Ceased
- 2002-11-07 DK DK02793806T patent/DK1448544T3/da active
- 2002-11-07 MX MXPA04004703A patent/MXPA04004703A/es active IP Right Grant
- 2002-11-07 DE DE60220179T patent/DE60220179T2/de not_active Expired - Lifetime
-
2004
- 2004-04-08 IL IL161325A patent/IL161325A/en not_active IP Right Cessation
- 2004-05-18 HR HR20040439A patent/HRP20040439A2/hr not_active Application Discontinuation
- 2004-05-19 EC EC2004005113A patent/ECSP045113A/es unknown
- 2004-06-18 NO NO20042583A patent/NO328563B1/no not_active IP Right Cessation
-
2005
- 2005-01-24 HK HK05100628A patent/HK1068349A1/xx not_active IP Right Cessation
-
2007
- 2007-07-13 CY CY20071100932T patent/CY1106726T1/el unknown
- 2007-09-10 IL IL185867A patent/IL185867A/en not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1068349A1 (en) | Substituted benzopyrans as selective estrogen receptor-beta agonists | |
ATE457308T1 (de) | Substituierte benzopyrane als selektive antagonisten am östrogenrezeptor-beta | |
CY1110443T1 (el) | Υποκατεστημενα βενζοπυρανια ως εκλεκτικοι αγωνιστες υποδοχεα-βητα οιστρογονων | |
MXPA04002070A (es) | Compuestos de indazol sustituidos para el tratamiento de la inflamacion. | |
PT925301E (pt) | Derivados altamente lipofilos de camptotecina | |
RS60503A (en) | Substituted alkylamine derivatives and methods of use | |
NZ511593A (en) | Substituted benzopyran analogs for the treatment of inflammation | |
MY141733A (en) | Benzimidazole and pyridylimidazole derivatives as ligands for gabaa receptors | |
PL367814A1 (en) | 4,5-dihydro-1h-pyrazole derivatives having potent cb1-antagonistic activity | |
MXPA03010134A (es) | Derivados de ciclohexan-1-4-diamina sustituidos. | |
AU2001231710A1 (en) | Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase | |
HK1080088A1 (zh) | 製備c-7取代的5-雄甾烯的方法 | |
WO2003024935A3 (en) | Substituted pyrazolyl compounds for the treatment of inflammation | |
WO2003027075A3 (en) | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation | |
PL371127A1 (en) | 6-aminomorphinane derivatives, method for the production and use thereof | |
MXPA04004606A (es) | Venenos de topoisomerasa solubilizados. | |
EP1453812A4 (en) | CYTOTOXIC AGENTS | |
AU2002357184A1 (en) | SUBSTITUTED 6H-DIBENZO(c,h)CHROMENES AS ESTROGENIC AGENTS | |
MY117975A (en) | Substituted imidazoles as dual histamine h1 and h3 agonists or antagonists | |
HUP0402283A3 (en) | Substituted 2-pyrrolidine-2-yl-1h-indole derivatives for the treatment of migraine, process for their preparation and pharmaceutical compositions containing them | |
ES2103237A1 (es) | Nuevo compuesto derivado del cromeno | |
SI1453820T1 (en) | Substituted 6h-dibenzo(c,h)chromenes as estrogenic agents |