IL159218A0 - Substituted benzopyran derivatives against arrhythmia - Google Patents

Substituted benzopyran derivatives against arrhythmia

Info

Publication number
IL159218A0
IL159218A0 IL15921802A IL15921802A IL159218A0 IL 159218 A0 IL159218 A0 IL 159218A0 IL 15921802 A IL15921802 A IL 15921802A IL 15921802 A IL15921802 A IL 15921802A IL 159218 A0 IL159218 A0 IL 159218A0
Authority
IL
Israel
Prior art keywords
sup
sub
group
alkyl group
benzopyran derivatives
Prior art date
Application number
IL15921802A
Other languages
English (en)
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of IL159218A0 publication Critical patent/IL159218A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15921802A 2001-06-25 2002-06-17 Substituted benzopyran derivatives against arrhythmia IL159218A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001190594 2001-06-25
PCT/JP2002/006012 WO2003000675A1 (en) 2001-06-25 2002-06-17 Substituted benzopyran derivatives against arrhythmia

Publications (1)

Publication Number Publication Date
IL159218A0 true IL159218A0 (en) 2004-06-01

Family

ID=19029343

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15921802A IL159218A0 (en) 2001-06-25 2002-06-17 Substituted benzopyran derivatives against arrhythmia
IL159218A IL159218A (en) 2001-06-25 2003-12-07 Substituted benzopyran derivatives against arrhythmia

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL159218A IL159218A (en) 2001-06-25 2003-12-07 Substituted benzopyran derivatives against arrhythmia

Country Status (17)

Country Link
US (1) US7041700B2 (xx)
EP (1) EP1401823B1 (xx)
KR (1) KR100869897B1 (xx)
CN (1) CN1279036C (xx)
AT (1) ATE305930T1 (xx)
CA (1) CA2450541A1 (xx)
CZ (1) CZ20033469A3 (xx)
DE (1) DE60206505T2 (xx)
HK (1) HK1063785A1 (xx)
HU (1) HUP0400362A3 (xx)
IL (2) IL159218A0 (xx)
NO (1) NO20035774L (xx)
NZ (1) NZ529916A (xx)
RU (1) RU2291867C2 (xx)
SK (1) SK15782003A3 (xx)
UA (1) UA77189C2 (xx)
WO (1) WO2003000675A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315950D0 (en) 2003-06-11 2003-08-13 Xention Discovery Ltd Compounds
TWI346112B (en) 2004-02-25 2011-08-01 Nissan Chemical Ind Ltd Benzopyran compound
US7647250B2 (en) * 2004-03-08 2010-01-12 Sap Ag Method and program product for event monitoring
CN1934116B (zh) 2004-03-23 2012-10-10 日产化学工业株式会社 用作抗心律失常剂的三环苯并吡喃化合物
GB0412986D0 (en) 2004-06-10 2004-07-14 Xention Discovery Ltd Compounds
US7576212B2 (en) 2004-12-09 2009-08-18 Xention Limited Thieno[2,3-B] pyridines as potassium channel inhibitors
US7714150B2 (en) 2005-04-12 2010-05-11 Solvay Pharmaceuticals Gmbh Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives
GB0525164D0 (en) 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
GB0815781D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815782D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB201105659D0 (en) 2011-04-01 2011-05-18 Xention Ltd Compounds
NO3175985T3 (xx) 2011-07-01 2018-04-28
AR090037A1 (es) 2011-11-15 2014-10-15 Xention Ltd Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
US20140357662A1 (en) 2011-11-15 2014-12-04 Xention Limited Thieno (2,3 - c) pyrazoles for use as potassium channel inhibitors
CA2862670A1 (en) 2012-01-27 2013-08-01 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
WO2014134419A1 (en) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Use of ikach blockers for the treatment of cardiac diseases

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES454888A1 (es) 1976-01-27 1978-05-01 Beecham Group Ltd Un procedimiento para la preparacion de nuevos cromados.
JPS5657786A (en) 1979-09-28 1981-05-20 Beecham Group Ltd Chromanol derivative* its manufacture and medicinal composition containing it
JPS5657785A (en) 1979-09-28 1981-05-20 Beecham Group Ltd Chromanol derivative* its manufacture and medicinal composition containing it
ZM7682A1 (en) 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
EP0091748B1 (en) 1982-04-08 1986-06-18 Beecham Group Plc Antihypertensive benzopyranols
GB8610911D0 (en) 1986-05-03 1986-06-11 Beecham Group Plc Active compounds
DK691488A (da) 1987-12-14 1989-06-15 Beecham Group Plc Hidtil ukendte forbindelser
US5097037A (en) * 1989-07-17 1992-03-17 Nissan Chemical Industries, Ltd. Process for the optical resolution of pyranobenzoxadiazole compounds
JP2876712B2 (ja) 1989-07-17 1999-03-31 日産化学工業株式会社 光学活性ピラノベンゾオキサジアゾール誘導体
US5095016A (en) * 1989-08-11 1992-03-10 Kaken Pharmaceutical Co., Ltd. Benzopyran compounds, processes for their production and pharmaceutical compositions
WO1991014694A1 (en) 1990-03-21 1991-10-03 Research Corporation Technologies, Inc. Chiral catalysts and epoxidation reactions catalyzed thereby
US5276168A (en) * 1990-06-18 1994-01-04 E. R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
AU651105B2 (en) * 1990-06-18 1994-07-14 E.R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
US5624954A (en) * 1991-06-13 1997-04-29 Smithkline Beecham P.L.C. Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity
JPH05301878A (ja) 1991-08-30 1993-11-16 Nissan Chem Ind Ltd 不斉エポキシ化反応
US5352814A (en) 1991-08-30 1994-10-04 Nissan Chemical Industries, Ltd. Asymmetric epoxidation reaction
DE69427278T2 (de) * 1994-02-23 2001-10-25 Nissan Chemical Industries, Ltd. Asymmetrisches Epoxidationsverfahren unter Verwendung von optisch-aktiven Mangankomplexen
JP2734457B2 (ja) 1994-02-23 1998-03-30 日産化学工業株式会社 不斉エポキシ化反応
EP0764159B1 (en) 1994-06-10 2000-08-09 Smithkline Beecham Plc C -4 amide substituted compounds and their use as therapeutic agents
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
JP4129601B2 (ja) 1996-07-26 2008-08-06 日産化学工業株式会社 クロマン誘導体
JPH11209366A (ja) 1998-01-23 1999-08-03 Nissan Chem Ind Ltd クロマン誘導体及び心不全治療薬
JP2002523451A (ja) * 1998-09-01 2002-07-30 ブリストル−マイヤーズ スクイブ カンパニー カリウムチャネル抑制剤および方法
JP2001151767A (ja) 1999-09-17 2001-06-05 Nissan Chem Ind Ltd ベンゾピラン誘導体

Also Published As

Publication number Publication date
CN1279036C (zh) 2006-10-11
US7041700B2 (en) 2006-05-09
IL159218A (en) 2009-12-24
NZ529916A (en) 2005-04-29
WO2003000675A1 (en) 2003-01-03
CA2450541A1 (en) 2003-01-03
SK15782003A3 (sk) 2004-05-04
RU2004101964A (ru) 2005-03-27
EP1401823B1 (en) 2005-10-05
UA77189C2 (en) 2006-11-15
KR100869897B1 (ko) 2008-11-24
CN1520406A (zh) 2004-08-11
NO20035774L (no) 2004-02-25
EP1401823A1 (en) 2004-03-31
RU2291867C2 (ru) 2007-01-20
HK1063785A1 (en) 2005-01-14
HUP0400362A2 (hu) 2004-08-30
ATE305930T1 (de) 2005-10-15
US20040152763A1 (en) 2004-08-05
CZ20033469A3 (cs) 2004-04-14
KR20040018391A (ko) 2004-03-03
HUP0400362A3 (en) 2007-05-29
DE60206505D1 (de) 2006-02-16
DE60206505T2 (de) 2006-07-06

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