IL154811D0 - Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure - Google Patents

Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure

Info

Publication number
IL154811D0
IL154811D0 IL15481101A IL15481101A IL154811D0 IL 154811 D0 IL154811 D0 IL 154811D0 IL 15481101 A IL15481101 A IL 15481101A IL 15481101 A IL15481101 A IL 15481101A IL 154811 D0 IL154811 D0 IL 154811D0
Authority
IL
Israel
Prior art keywords
agent
anti
inhibiting
sampling
decrease
Prior art date
Application number
IL15481101A
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US23116000P priority Critical
Application filed by Alza Corp filed Critical Alza Corp
Priority to PCT/US2001/027551 priority patent/WO2002019985A2/en
Publication of IL154811D0 publication Critical patent/IL154811D0/en

Links

Abstract

This invention relates to a method for inhibiting a decrease in the transdermal flux of an agent that is being transdermally delivered or sampled over a prolonged period of time wherein the delivery or sampling involves disrupting at least the stratum corneum layer of the skin to form pathways through which the agent passes. The desired result is achieved by co-delivering or co-sampling the agent with an amount of at least one anti-healing agent wherein the amount of the anti-healing agent is effective in inhibiting a decrease in the agent transdermal flux compared to when the delivery or sampling of the agent is done under substantially identical conditions except in the absence of the anti-healing agent(s).
IL15481101A 2000-09-08 2001-09-06 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure IL154811D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US23116000P true 2000-09-08 2000-09-08
PCT/US2001/027551 WO2002019985A2 (en) 2000-09-08 2001-09-06 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure

Publications (1)

Publication Number Publication Date
IL154811D0 true IL154811D0 (en) 2003-10-31

Family

ID=22867983

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15481101A IL154811D0 (en) 2000-09-08 2001-09-06 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure

Country Status (24)

Country Link
US (1) US7438926B2 (en)
EP (1) EP1335711B1 (en)
JP (2) JP5507030B2 (en)
KR (1) KR100764699B1 (en)
CN (1) CN100421653C (en)
AT (1) AT367805T (en)
AU (2) AU2001288774B2 (en)
BR (1) BR0113749A (en)
CA (1) CA2422200A1 (en)
CZ (1) CZ2003687A3 (en)
DE (1) DE60129585T2 (en)
DK (1) DK1335711T3 (en)
EE (1) EE200300095A (en)
ES (1) ES2290166T3 (en)
IL (1) IL154811D0 (en)
MA (1) MA25958A1 (en)
MX (1) MXPA03002122A (en)
NO (1) NO20031071L (en)
NZ (1) NZ524646A (en)
PL (1) PL365603A1 (en)
PT (1) PT1335711E (en)
RU (1) RU2272618C2 (en)
WO (1) WO2002019985A2 (en)
ZA (1) ZA200302700B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03002122A (en) * 2000-09-08 2004-09-10 Johnson & Johnson Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure.
KR100812097B1 (en) * 2000-10-26 2008-03-12 알자 코포레이션 Transdermal drug delivery devices having coated microprotrusions
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
CA2530531A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
UY28398A1 (en) * 2003-07-02 2004-11-08 Alza Corp Method and immunization patch available microprojection
EP1658035A4 (en) 2003-08-25 2007-08-22 3M Innovative Properties Co Delivery of immune response modifier compounds
AU2004286232A1 (en) * 2003-10-23 2005-05-12 Alza Corporation Compositions of stabilized DNA for coating microprojections
CN1897898A (en) * 2003-10-24 2007-01-17 阿尔扎公司 Pretreatment method and system for enhancing transdermal drug delivery
US20050106209A1 (en) * 2003-11-13 2005-05-19 Mahmoud Ameri Composition and apparatus for transdermal delivery
MXPA06011429A (en) 2004-04-01 2007-04-25 Johnson & Johnson Apparatus and method for transdermal delivery of influenza vaccine.
WO2005103303A2 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of multiple vaccines
WO2005102334A2 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of fentany-based agents
KR20070042573A (en) * 2004-08-11 2007-04-23 알자 코포레이션 Apparatus and method for transdermal delivery of natriuretic peptides
WO2006055844A2 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Method of contact coating a microneedle array
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2629193C (en) * 2005-11-18 2016-03-29 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US7846488B2 (en) * 2004-11-18 2010-12-07 3M Innovative Properties Company Masking method for coating a microneedle array
CA2597931A1 (en) * 2005-02-16 2006-08-24 Alza Corporation Apparatus and method for transdermal delivery of erythropoetin-based agents
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
EP2018835B1 (en) * 2007-07-09 2014-03-05 Augustinus Bader Agent-eluting plaster
US8617487B2 (en) 2009-03-25 2013-12-31 Venture Lending & Leasing Vi, Inc. Saliva sample collection systems
JPWO2011010456A1 (en) * 2009-07-24 2012-12-27 株式会社ネクスト21 NSAIDs-containing external preparation and method for producing the external preparation
EP2818159A1 (en) * 2013-06-25 2014-12-31 LTS LOHMANN Therapie-Systeme AG Device having transdermal therapeutic system, positioning and penetration aid
US9987361B1 (en) * 2014-12-29 2018-06-05 Noven Pharmaceuticals, Inc. Compositions and method for sustained drug delivery by active transdermal technology
DE102017126501A1 (en) 2017-11-10 2019-05-16 Lts Lohmann Therapie-Systeme Ag Micro needle system for the application of a hepatitis vaccine

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (en) 1972-02-14 1973-08-13 Ici Ltd dressings
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
IL109037A (en) * 1993-03-19 1999-01-26 Cellegy Pharma Inc Compositions for inducing phase separation of epithelial lipid bilayers and preparation of said compositions
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
JPH10510175A (en) * 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト Transdermal system
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
DE19525607A1 (en) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneal drug release system
US5902603A (en) * 1995-09-14 1999-05-11 Cygnus, Inc. Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use
DE19541260A1 (en) * 1995-11-06 1997-05-07 Lohmann Therapie Syst Lts A therapeutic preparation for the transdermal application of active substances through the skin
US6230051B1 (en) 1996-06-18 2001-05-08 Alza Corporation Device for enhancing transdermal agent delivery or sampling
EP1314400B1 (en) * 1996-12-31 2007-06-20 Altea Therapeutics Corporation Microporation of tissue for delivery of bioactive agents
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
WO1998011937A1 (en) 1996-09-17 1998-03-26 Deka Products Limited Partnership System for delivery of drugs by transport
DK0957972T3 (en) 1996-12-20 2003-07-21 Alza Corp A device and method for increasing the transdermal average flux
DE19654391A1 (en) 1996-12-27 1998-07-02 Basf Ag Catalyst for the selective production of propylene from propane
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ES2314995T3 (en) 1997-12-11 2009-03-16 Alza Corporation Device for improving the flow of tansdermic agents.
ES2244106T3 (en) * 1997-12-11 2005-12-01 Alza Corporation Device for transdermal agent flux.
CN1161164C (en) * 1997-12-11 2004-08-11 阿尔扎有限公司 Device for enhaning transdermal agent flux
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
EP1187653B1 (en) * 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
JP2002543942A (en) * 1999-05-17 2002-12-24 ティー フロック,ステファン A remotely controlled and local control, transport of pharmaceutical compounds by means of electromagnetic energy
WO2001041863A1 (en) * 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
AU782610B2 (en) * 1999-12-10 2005-08-11 Alza Corporation Skin treatment apparatus for sustained transdermal drug delivery
MXPA03002122A (en) * 2000-09-08 2004-09-10 Johnson & Johnson Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure.
KR100812097B1 (en) * 2000-10-26 2008-03-12 알자 코포레이션 Transdermal drug delivery devices having coated microprotrusions
US20040115167A1 (en) * 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors

Also Published As

Publication number Publication date
BR0113749A (en) 2004-06-22
EP1335711A2 (en) 2003-08-20
JP2013256500A (en) 2013-12-26
PL365603A1 (en) 2005-01-10
MXPA03002122A (en) 2004-09-10
CN100421653C (en) 2008-10-01
US20020102292A1 (en) 2002-08-01
KR20030074595A (en) 2003-09-19
NZ524646A (en) 2004-10-29
WO2002019985A3 (en) 2002-09-06
EP1335711B1 (en) 2007-07-25
NO20031071D0 (en) 2003-03-07
KR100764699B1 (en) 2007-10-08
DE60129585T2 (en) 2008-04-17
AT367805T (en) 2007-08-15
US7438926B2 (en) 2008-10-21
JP2004508319A (en) 2004-03-18
DE60129585D1 (en) 2007-09-06
JP5507030B2 (en) 2014-05-28
EE200300095A (en) 2005-02-15
DK1335711T3 (en) 2007-11-26
ES2290166T3 (en) 2008-02-16
CA2422200A1 (en) 2002-03-14
CN1473037A (en) 2004-02-04
RU2272618C2 (en) 2006-03-27
NO20031071L (en) 2003-05-06
CZ2003687A3 (en) 2004-01-14
ZA200302700B (en) 2004-08-13
PT1335711E (en) 2007-09-05
AU2001288774B2 (en) 2006-06-29
WO2002019985A2 (en) 2002-03-14
AU8877401A (en) 2002-03-22
MA25958A1 (en) 2003-12-31

Similar Documents

Publication Publication Date Title
ES2284888T3 (en) Oral administration of 6-hydroxy-oximorphone used as an analgesic.
DE60228293D1 (en) Implantable devices for the treatment of pain by delivery of fentanyl and fentanyl-related
DE60143360D1 (en) Composition for the transdermal and / or transmucosal administration of active ingredients which guarantees adequate therapeutic levels
DE60335957D1 (en) Method for treating post-operative pain by administering an antibody against nerve growth factor and compositions containing thereof
TW453994B (en) Substituted pyridines as selective cyclooxygenase-2 inhibitors
YU92202A (en) Methods and compositions for treating flaviviruses and pestiviruses
UA85055C2 (en) Use of myostatin (gdf8) inhibitor in conjunction with corticosteroid for treating neuromuscular disorder
DE60328128D1 (en) Method for pain treatment by administration of an antagonistic antibody against the nerve growth factor and an opioid analgetics, and compositions containing thereof
CA2201725A1 (en) Composition, device and method for electrotransport agent delivery
RS69704A (en) Treating bening prostate hyperplasia with sarms
NZ537359A (en) Topical cosmetic compositions for transdermal delivery
WO2004050016A3 (en) Delivery of pharmaceutical agents via the human insulin receptor
MXPA02000096A (en) Pharmaceutical composition for the treatment of cns and other disorders.
WO2008027371A3 (en) Low profile bioactive agent delivery device
WO2002042462A3 (en) Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
WO2002028354A3 (en) Delivery of anesthetic to a wall forming passage
IL174066A (en) Stent delivery system
IL167436A (en) Human anti- ifn-gamma neutralizing antibodies as selective ifn-gamma pathway inhibitors
AU3402102A (en) Method and device for the treatment of vulnerable tissue site
WO2007085019A3 (en) Methods of treating or preventing sinusitis with oxidative reductive potential water solution
HK1046096A1 (en) Solutions and methods for inhibitions of pain, inflammation and cartilage degradation
AU2005299614A8 (en) Medical device delivery catheter
WO2005044178A3 (en) Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
WO2005011772A3 (en) Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agents
AU2002234192A8 (en) Methods and transdermal compositions for pain relief