IL149628A0 - Antithrombotic compound - Google Patents

Antithrombotic compound

Info

Publication number
IL149628A0
IL149628A0 IL14962800A IL14962800A IL149628A0 IL 149628 A0 IL149628 A0 IL 149628A0 IL 14962800 A IL14962800 A IL 14962800A IL 14962800 A IL14962800 A IL 14962800A IL 149628 A0 IL149628 A0 IL 149628A0
Authority
IL
Israel
Prior art keywords
antithrombotic compound
antithrombotic
compound
Prior art date
Application number
IL14962800A
Other languages
English (en)
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of IL149628A0 publication Critical patent/IL149628A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL14962800A 1999-12-07 2000-12-01 Antithrombotic compound IL149628A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99204172 1999-12-07
PCT/EP2000/012155 WO2001042262A2 (en) 1999-12-07 2000-12-01 Antithrombotic compound

Publications (1)

Publication Number Publication Date
IL149628A0 true IL149628A0 (en) 2002-11-10

Family

ID=8240976

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14962800A IL149628A0 (en) 1999-12-07 2000-12-01 Antithrombotic compound
IL149628A IL149628A (en) 1999-12-07 2002-05-14 Antithrombotic polysulfated pentasaccharides, their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL149628A IL149628A (en) 1999-12-07 2002-05-14 Antithrombotic polysulfated pentasaccharides, their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US6875755B2 (pl)
EP (1) EP1237897B1 (pl)
JP (1) JP4820517B2 (pl)
KR (1) KR100776607B1 (pl)
CN (1) CN1195767C (pl)
AR (1) AR026726A1 (pl)
AU (1) AU781846B2 (pl)
BR (1) BR0016217A (pl)
CA (1) CA2393042C (pl)
CO (1) CO5251449A1 (pl)
CZ (1) CZ303385B6 (pl)
HK (1) HK1047593A1 (pl)
HU (1) HUP0203471A3 (pl)
IL (2) IL149628A0 (pl)
NO (1) NO323059B1 (pl)
NZ (1) NZ519100A (pl)
PE (1) PE20010935A1 (pl)
PL (1) PL202840B1 (pl)
RU (1) RU2266913C2 (pl)
SK (1) SK287682B6 (pl)
TW (1) TWI289566B (pl)
WO (1) WO2001042262A2 (pl)
ZA (1) ZA200203799B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1440077E (pt) * 2001-09-07 2013-06-04 Alchemia Ltd Pentassacáridos de heparina sintéticos
WO2004007468A1 (en) 2002-07-15 2004-01-22 Merck & Co., Inc. Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes
ES2291680T3 (es) 2002-10-07 2008-03-01 MERCK & CO., INC. Antidiabeticos beta-amino heterociclicos inhibidores de la dipeptidil peptidasa.
CA2504735C (en) * 2002-11-07 2009-06-23 Merck & Co., Inc. Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
AU2004206812A1 (en) 2003-01-17 2004-08-05 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
AU2004210149A1 (en) 2003-01-31 2004-08-19 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CN1787823A (zh) 2003-05-14 2006-06-14 麦克公司 作为二肽基肽酶抑制剂用于治疗或预防糖尿病的3－氨基－4－苯基丁酸衍生物
DE602004026440D1 (de) 2003-06-06 2010-05-20 Merck Sharp & Dohme Kondensierte indole als dipeptidyl-peptidase-hemmer zur behandlung oder prävention von diabetes
AU2004249163A1 (en) 2003-06-17 2004-12-29 Merck & Co., Inc. Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
DE602004018503D1 (de) 2003-07-31 2009-01-29 Merck & Co Inc Hexahydrodiazepinone als inhibitoren des dipeptidylpeptidase-iv zur behandlung bzw. prävention von diabetes
EP1574516A1 (en) 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
TW200621794A (en) * 2004-10-06 2006-07-01 Akzo Nobel Nv Pulmonary administration of an antithrombotic compound
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
BRPI0617215A2 (pt) * 2005-10-10 2011-07-19 Organon Nv composto anti-trombótico, composição farmacêutica, e, uso do composto
CA2784529C (en) 2009-12-18 2018-05-22 Catalent France Beinheim Sa Pharmaceutical oral dosage form containing a synthetic oligosaccharide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
ES2147216T3 (es) * 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
BR9911300A (pt) * 1998-06-17 2001-04-03 Akzo Nobel Nv Composto, composição farmacêutica, e, uso do composto

Also Published As

Publication number Publication date
NO20022689L (no) 2002-06-06
HK1047593A1 (zh) 2003-02-28
PE20010935A1 (es) 2001-09-20
JP2003520208A (ja) 2003-07-02
IL149628A (en) 2010-04-29
CO5251449A1 (es) 2003-02-28
TWI289566B (en) 2007-11-11
CN1195767C (zh) 2005-04-06
SK7942002A3 (en) 2002-09-10
CZ20021958A3 (cs) 2002-08-14
WO2001042262A2 (en) 2001-06-14
AU781846B2 (en) 2005-06-16
AU2003801A (en) 2001-06-18
US6875755B2 (en) 2005-04-05
CN1407989A (zh) 2003-04-02
KR20020070988A (ko) 2002-09-11
SK287682B6 (sk) 2011-06-06
BR0016217A (pt) 2002-09-10
PL202840B1 (pl) 2009-07-31
CZ303385B6 (cs) 2012-08-29
AR026726A1 (es) 2003-02-26
HUP0203471A3 (en) 2003-03-28
US20030114361A1 (en) 2003-06-19
PL355484A1 (pl) 2004-05-04
ZA200203799B (en) 2003-10-29
EP1237897B1 (en) 2015-01-14
EP1237897A2 (en) 2002-09-11
WO2001042262A3 (en) 2001-12-13
KR100776607B1 (ko) 2007-11-16
RU2266913C2 (ru) 2005-12-27
HUP0203471A2 (hu) 2003-02-28
CA2393042A1 (en) 2001-06-14
NO20022689D0 (no) 2002-06-06
NZ519100A (en) 2004-09-24
JP4820517B2 (ja) 2011-11-24
NO323059B1 (no) 2006-12-27
CA2393042C (en) 2011-06-28

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