IL145641A0 - C7 ester substituted taxanes as antitumor agents - Google Patents
C7 ester substituted taxanes as antitumor agentsInfo
- Publication number
- IL145641A0 IL145641A0 IL14564101A IL14564101A IL145641A0 IL 145641 A0 IL145641 A0 IL 145641A0 IL 14564101 A IL14564101 A IL 14564101A IL 14564101 A IL14564101 A IL 14564101A IL 145641 A0 IL145641 A0 IL 145641A0
- Authority
- IL
- Israel
- Prior art keywords
- antitumor agents
- ester substituted
- substituted taxanes
- taxanes
- ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17979400P | 2000-02-02 | 2000-02-02 | |
| PCT/US2001/003385 WO2001057027A1 (fr) | 2000-02-02 | 2001-02-02 | Taxanes substitues par ester en c7 utilises comme agents anticancereux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL145641A0 true IL145641A0 (en) | 2002-06-30 |
Family
ID=22658029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14564101A IL145641A0 (en) | 2000-02-02 | 2001-02-02 | C7 ester substituted taxanes as antitumor agents |
Country Status (35)
| Country | Link |
|---|---|
| US (3) | US6610860B2 (fr) |
| EP (1) | EP1183253B8 (fr) |
| JP (1) | JP2003522167A (fr) |
| KR (1) | KR100784161B1 (fr) |
| CN (1) | CN1362955A (fr) |
| AR (1) | AR030188A1 (fr) |
| AT (1) | ATE396188T1 (fr) |
| AU (1) | AU776051B2 (fr) |
| BG (1) | BG65279B1 (fr) |
| BR (1) | BR0104749A (fr) |
| CA (1) | CA2368993C (fr) |
| CO (1) | CO5280224A1 (fr) |
| CZ (1) | CZ298484B6 (fr) |
| DE (1) | DE60134094D1 (fr) |
| DK (1) | DK1183253T3 (fr) |
| ES (1) | ES2307588T3 (fr) |
| GE (1) | GEP20043322B (fr) |
| HK (1) | HK1047938A1 (fr) |
| HU (1) | HUP0200917A3 (fr) |
| IL (1) | IL145641A0 (fr) |
| MX (1) | MXPA01009901A (fr) |
| MY (1) | MY137637A (fr) |
| NO (1) | NO327982B1 (fr) |
| NZ (1) | NZ514409A (fr) |
| PL (1) | PL202668B1 (fr) |
| PT (1) | PT1183253E (fr) |
| RO (1) | RO121777B1 (fr) |
| RU (1) | RU2265017C2 (fr) |
| SA (1) | SA01220045B1 (fr) |
| SK (1) | SK13712001A3 (fr) |
| TR (1) | TR200102856T1 (fr) |
| TW (1) | TWI291873B (fr) |
| UA (1) | UA75573C2 (fr) |
| WO (1) | WO2001057027A1 (fr) |
| ZA (1) | ZA200108060B (fr) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5280224A1 (es) | 2000-02-02 | 2003-05-30 | Univ Florida State Res Found | Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen |
| CA2367661A1 (fr) * | 2000-02-02 | 2001-08-09 | Robert A. Holton | Formulations de taxane possedant une solubilite amelioree |
| CA2354486A1 (fr) * | 2001-07-31 | 2003-01-31 | Florida State University Research Foundation, Inc. | Taxanes substitues avec un ester en c7 |
| SG125889A1 (en) * | 2001-08-01 | 2006-10-30 | Univ Florida State Res Found | C7 ester subsituted taxanes |
| KR100819578B1 (ko) * | 2001-08-01 | 2008-04-04 | 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 | Ｃ７ 에스테르 치환된 탁산 |
| US20030082229A1 (en) * | 2001-11-01 | 2003-05-01 | Board Of Regents, The University Of Texas Systems | Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use |
| US8012950B2 (en) * | 2003-08-29 | 2011-09-06 | Wisconsin Alumni Research Foundation | Method to diagnose and treat degenerative joint disease |
| EP1664033B1 (fr) | 2003-09-25 | 2007-11-07 | Tapestry Pharmaceuticals, Inc. | Analogues de 9,10-alpha,alpha-oh-taxane et procedes de fabrication correspondants |
| SI1664033T1 (sl) * | 2003-09-25 | 2008-04-30 | Tapestry Pharmaceuticals Inc | Analogi 9,10-alfa,alfa-oh-taksana in postopki za proizvodnjo le-teh |
| JP2007527432A (ja) | 2004-03-05 | 2007-09-27 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | Ｃ７ラクチルオキシ置換タキサン |
| TW200533339A (en) | 2004-03-16 | 2005-10-16 | Bristol Myers Squibb Co | Therapeutic synergy of anti-cancer compounds |
| CN101438252A (zh) * | 2004-10-07 | 2009-05-20 | 爱莫里大学 | 多功能纳米粒子共轭体及其应用 |
| CA2585125C (fr) | 2004-10-25 | 2014-04-22 | Lee Morgan | Sels d'yperite d'isophosphoramide et analogues de ceux-ci utilises en tant qu'agents anti-tumoraux |
| US20060216767A1 (en) * | 2005-03-22 | 2006-09-28 | Saladax Biomedical Inc. | Docetaxel immunoassay |
| PL217731B1 (pl) | 2006-06-01 | 2014-08-29 | Tomasz Byrski | Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi |
| WO2008106621A1 (fr) | 2007-02-28 | 2008-09-04 | Tapestry Pharmaceuticals, Inc | Analogues de taxane destinés à traiter un cancer du cerveau |
| US11786504B2 (en) | 2006-09-28 | 2023-10-17 | Tapestry Pharmaceuticals, Inc. | Taxane analogs for the treatment of brain cancer |
| WO2008121476A1 (fr) | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Analogues de taxane biologiquement actifs, et procédés de traitement par administration orale |
| US11873308B2 (en) | 2006-11-06 | 2024-01-16 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
| WO2008098138A1 (fr) | 2007-02-07 | 2008-08-14 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Composés macrocycliques de synthèse |
| AU2008236684B2 (en) | 2007-04-06 | 2013-04-18 | Ziopharm Oncology, Inc. | Salts of isophosphoramide mustard and analogs thereof |
| CA2732290A1 (fr) | 2008-07-31 | 2010-02-04 | Ziopharm Oncology, Inc. | Synthese et formulations de sels de moutarde d'isophosphoramide et de leurs analogues |
| US8361992B2 (en) | 2009-02-24 | 2013-01-29 | Dekk-Tec, Inc. | Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents |
| WO2010138686A1 (fr) | 2009-05-29 | 2010-12-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Agents s'opposant au gène mdr1 |
| BR112012022552A8 (pt) | 2010-03-10 | 2017-12-05 | Stanford Res Inst Int | uso de fenoterol e de análogos de fenoterol no tratamento de gliobastomas e astrocitomas e composição farmacêutica compreendendo os referidos compostos |
| WO2013009475A1 (fr) | 2011-07-11 | 2013-01-17 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Conjugués anticorps-fluorophore photosensibilisants |
| WO2012033601A1 (fr) | 2010-08-20 | 2012-03-15 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Thiosemicarbazones à activité anti-mdr1 |
| CA2874655C (fr) | 2012-05-25 | 2020-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Procedes de regulation de troubles et maladies associes a une activite de recepteur cannabinoide |
| EP3620470B1 (fr) | 2013-10-11 | 2023-07-26 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Anticorps tem8 et leur utilisation |
| WO2016022896A1 (fr) | 2014-08-08 | 2016-02-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Élimination photo-contrôlée de cibles in vitro et in vivo |
| KR20200081438A (ko) | 2017-10-31 | 2020-07-07 | 웨스턴 온콜리틱스 리미티드 | 전신 전달을 위한 플랫폼 종양용해 벡터 |
| WO2019099615A1 (fr) | 2017-11-17 | 2019-05-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Utilisation de copeptine pour moduler la réponse immunitaire et l'hématopoïèse et stimuler la croissance osseuse |
| EP3774912A1 (fr) | 2018-04-10 | 2021-02-17 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Combinaison de photoimmunothérapie proche infrarouge ciblant des cellules cancéreuses et activation immunitaire hôte |
| KR20220031054A (ko) | 2019-07-02 | 2022-03-11 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | Egfrviii에 결합하는 단일클론 항체 및 이의 용도 |
| WO2021154705A1 (fr) | 2020-01-27 | 2021-08-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Oligonucléotides antisens rab13 et net1 pour traiter le cancer métastatique |
| WO2022165277A1 (fr) | 2021-01-29 | 2022-08-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polythérapie à base de photo-immunothérapie dans le proche infrarouge (nir-pit) pour traiter le cancer |
| CN117241813A (zh) | 2021-04-30 | 2023-12-15 | 卡利威尔免疫治疗公司 | 用于修饰的mhc表达的溶瘤病毒 |
| WO2024006965A1 (fr) | 2022-06-30 | 2024-01-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anticorps spécifiques de cd25 et leurs utilisations |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US5321128A (en) * | 1988-09-06 | 1994-06-14 | Kabi Pharmacia Ab | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| SE463189B (sv) | 1989-03-13 | 1990-10-22 | Eston Joensson | Preparat avsett att tillfoeras amalgamfyllningar i taender foer att daerigenom hindra eller minska avgaang av kvicksilver eller kvicksilveraanga |
| US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| FR2679230B1 (fr) | 1991-07-16 | 1993-11-19 | Rhone Poulenc Rorer Sa | Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent. |
| US5243045A (en) | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
| US5283253A (en) | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
| US5721268A (en) | 1991-09-23 | 1998-02-24 | Florida State University | C7 taxane derivatives and pharmaceutical compositions containing them |
| US5227400A (en) | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
| US5714513A (en) | 1991-09-23 | 1998-02-03 | Florida State University | C10 taxane derivatives and pharmaceutical compositions |
| US5489601A (en) * | 1991-09-23 | 1996-02-06 | Florida State University | Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them |
| US5430160A (en) | 1991-09-23 | 1995-07-04 | Florida State University | Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides |
| US5350866A (en) | 1991-09-23 | 1994-09-27 | Bristol-Myers Squibb Company | 10-desacetoxytaxol derivatives |
| CA2087359A1 (fr) | 1992-01-15 | 1993-07-16 | Ramesh N. Patel | Procedes enzymatiques pour la resolution d'un melange enantiometrique de composes utiles comme intermediaires pour la preparation de taxanes |
| US5272171A (en) | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US5200534A (en) | 1992-03-13 | 1993-04-06 | University Of Florida | Process for the preparation of taxol and 10-deacetyltaxol |
| ATE181551T1 (de) | 1992-04-17 | 1999-07-15 | Abbott Lab | Taxol-derivate |
| US5248796A (en) | 1992-06-18 | 1993-09-28 | Bristol-Myers Squibb Company | Taxol derivatives |
| US5319112A (en) | 1992-08-18 | 1994-06-07 | Virgnia Tech Intellectual Properties, Inc. | Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol |
| WO1994005282A1 (fr) | 1992-09-04 | 1994-03-17 | The Scripps Research Institute | Derives de taxol hydrosolubles |
| CA2100808A1 (fr) | 1992-10-01 | 1994-04-02 | Vittorio Farina | Desoxytaxols |
| EP1251127B1 (fr) | 1992-12-23 | 2005-11-09 | Bristol-Myers Squibb Company | Taxannes portant une chaine latérale et leurs intermédiaires |
| IL108443A0 (en) * | 1993-01-29 | 1994-04-12 | Univ Florida State | C7 taxane derivatives and pharmaceutical compositions containing them |
| US5703247A (en) | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
| SG73401A1 (en) * | 1993-03-22 | 2000-06-20 | Univ Florida State | Taxanes having alkoxy alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing the same |
| IL109049A (en) * | 1993-03-22 | 2006-12-31 | Univ Florida State | Texans have a side chain that is converted into pyridyl and pharmaceutical preparations that contain them |
| JP3759601B2 (ja) * | 1993-03-22 | 2006-03-29 | フロリダ・ステート・ユニバーシティー | アミノ置換側鎖を有するタキサン |
| PT703909E (pt) | 1993-06-11 | 2000-10-31 | Upjohn Co | Utilizacao de delta-6,7-taxois antineoplasticos e composicoes farmaceuticas que os contem |
| IL109926A (en) | 1993-06-15 | 2000-02-29 | Bristol Myers Squibb Co | Methods for the preparation of taxanes and microorganisms and enzymes utilized therein |
| TW397866B (en) | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
| FR2711369B1 (fr) | 1993-10-20 | 1995-11-17 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent. |
| US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
| US5414869A (en) * | 1993-11-26 | 1995-05-16 | Thomson; Margaret I. | Knotless scarf and method of making same |
| AU4133096A (en) * | 1994-10-28 | 1996-05-23 | Research Foundation Of The State University Of New York, The | Taxoid derivatives, their preparation and their use as antitumor agents |
| TW354293B (en) | 1995-06-06 | 1999-03-11 | Bristol Myers Squibb Co | Prodrugs of paclitaxel derivatives |
| US5780653A (en) | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
| WO1997009979A1 (fr) | 1995-09-13 | 1997-03-20 | Florida State University | Taxanes a effet radiosensibilisant et leurs preparations pharmaceutiques |
| US5767297A (en) | 1997-02-05 | 1998-06-16 | Ensuiko Sugar Refining Co., Ltd. | Taxoid derivative and method of producing thereof |
| FR2745814B1 (fr) * | 1996-03-06 | 1998-04-03 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| CN1221412A (zh) | 1996-05-06 | 1999-06-30 | 佛罗里达州立大学 | 1－脱氧浆果赤霉素ⅲ,1－脱氧紫杉醇和1－脱氧紫杉醇类似物及其制备方法 |
| WO1997044027A1 (fr) * | 1996-05-17 | 1997-11-27 | Merck & Co., Inc. | Compositions de traitement journalier monodose de maladies a mediation cyclooxygenase-2 |
| US6576636B2 (en) | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| EP0914116B1 (fr) * | 1996-05-22 | 2000-10-11 | Protarga Inc. | Compositions contenant des conjugues d'acide cis-docosahexanoique et de taxotere |
| US5811452A (en) | 1997-01-08 | 1998-09-22 | The Research Foundation Of State University Of New York | Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof |
| US5912264A (en) | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
| US7288665B1 (en) | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
| EP1022284B1 (fr) * | 1997-10-08 | 2004-05-12 | Bio Research Corporation of Yokohama | Derives taxoides et leur procede de production |
| US6136988A (en) | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
| US5964739A (en) * | 1998-06-18 | 1999-10-12 | Champ; Raynido A. | Safety disposable needle structure |
| US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| TR200103747T2 (tr) | 1999-06-21 | 2002-04-22 | Napro Biotherapeutics, Inc. | C-2 Hidroksil korumalı N-Akril (2R, 3S)-3- Fenilizoserin ile aktifleştirilen esterler ve bunların üretilmesi yöntemi |
| WO2001025223A1 (fr) * | 1999-10-06 | 2001-04-12 | The Research Foundation Of State University Of New York | Stabilisation de systemes disperses contenant du taxane |
| AU3481001A (en) | 2000-02-02 | 2001-08-14 | Florida State University Research Foundation, Inc. | Taxane formulations having improved solubility |
| CO5280224A1 (es) | 2000-02-02 | 2003-05-30 | Univ Florida State Res Found | Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen |
| CA2367661A1 (fr) * | 2000-02-02 | 2001-08-09 | Robert A. Holton | Formulations de taxane possedant une solubilite amelioree |
| IT1319168B1 (it) | 2000-03-17 | 2003-09-26 | Indena Spa | Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono. |
-
2001
- 2001-01-31 CO CO01007075A patent/CO5280224A1/es not_active Application Discontinuation
- 2001-01-31 AR ARP010100463A patent/AR030188A1/es not_active Application Discontinuation
- 2001-02-02 GE GE4514A patent/GEP20043322B/en unknown
- 2001-02-02 MY MYPI20010481A patent/MY137637A/en unknown
- 2001-02-02 JP JP2001557859A patent/JP2003522167A/ja active Pending
- 2001-02-02 TR TR2001/02856T patent/TR200102856T1/xx unknown
- 2001-02-02 AU AU33239/01A patent/AU776051B2/en not_active Ceased
- 2001-02-02 CA CA002368993A patent/CA2368993C/fr not_active Expired - Fee Related
- 2001-02-02 SK SK1371-2001A patent/SK13712001A3/sk unknown
- 2001-02-02 RU RU2001129507/04A patent/RU2265017C2/ru not_active IP Right Cessation
- 2001-02-02 MX MXPA01009901A patent/MXPA01009901A/es active IP Right Grant
- 2001-02-02 EP EP01905349A patent/EP1183253B8/fr not_active Expired - Lifetime
- 2001-02-02 PT PT01905349T patent/PT1183253E/pt unknown
- 2001-02-02 RO ROA200101085A patent/RO121777B1/ro unknown
- 2001-02-02 ES ES01905349T patent/ES2307588T3/es not_active Expired - Lifetime
- 2001-02-02 BR BR0104749-3A patent/BR0104749A/pt not_active IP Right Cessation
- 2001-02-02 UA UA2001106734A patent/UA75573C2/uk unknown
- 2001-02-02 IL IL14564101A patent/IL145641A0/xx unknown
- 2001-02-02 HU HU0200917A patent/HUP0200917A3/hu unknown
- 2001-02-02 CZ CZ20013503A patent/CZ298484B6/cs not_active IP Right Cessation
- 2001-02-02 US US09/775,851 patent/US6610860B2/en not_active Expired - Fee Related
- 2001-02-02 DE DE60134094T patent/DE60134094D1/de not_active Expired - Fee Related
- 2001-02-02 WO PCT/US2001/003385 patent/WO2001057027A1/fr active IP Right Grant
- 2001-02-02 KR KR1020017012600A patent/KR100784161B1/ko not_active IP Right Cessation
- 2001-02-02 AT AT01905349T patent/ATE396188T1/de not_active IP Right Cessation
- 2001-02-02 PL PL350026A patent/PL202668B1/pl not_active IP Right Cessation
- 2001-02-02 CN CN01800306A patent/CN1362955A/zh active Pending
- 2001-02-02 DK DK01905349T patent/DK1183253T3/da active
- 2001-02-02 NZ NZ514409A patent/NZ514409A/xx unknown
- 2001-03-06 TW TW090102237A patent/TWI291873B/zh active
- 2001-04-11 SA SA1220045A patent/SA01220045B1/ar unknown
- 2001-10-01 NO NO20014759A patent/NO327982B1/no not_active IP Right Cessation
- 2001-10-01 ZA ZA200108060A patent/ZA200108060B/en unknown
- 2001-10-01 BG BG105967A patent/BG65279B1/bg unknown
-
2003
- 2003-01-07 HK HK03100173.6A patent/HK1047938A1/zh unknown
- 2003-06-25 US US10/606,027 patent/US7186849B2/en not_active Expired - Fee Related
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2007
- 2007-01-09 US US11/621,321 patent/US20070249708A1/en not_active Abandoned
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