IL137974A0 - Indole derivatives having antiviral activity - Google Patents

Indole derivatives having antiviral activity

Info

Publication number
IL137974A0
IL137974A0 IL13797499A IL13797499A IL137974A0 IL 137974 A0 IL137974 A0 IL 137974A0 IL 13797499 A IL13797499 A IL 13797499A IL 13797499 A IL13797499 A IL 13797499A IL 137974 A0 IL137974 A0 IL 137974A0
Authority
IL
Israel
Prior art keywords
antiviral activity
indole derivatives
indole
derivatives
antiviral
Prior art date
Application number
IL13797499A
Other languages
English (en)
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of IL137974A0 publication Critical patent/IL137974A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IL13797499A 1998-03-26 1999-03-26 Indole derivatives having antiviral activity IL137974A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7820398 1998-03-26
PCT/JP1999/001547 WO1999050245A1 (fr) 1998-03-26 1999-03-26 Derives d'indole exerçant une activite antivirale

Publications (1)

Publication Number Publication Date
IL137974A0 true IL137974A0 (en) 2001-10-31

Family

ID=13655476

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13797499A IL137974A0 (en) 1998-03-26 1999-03-26 Indole derivatives having antiviral activity

Country Status (17)

Country Link
US (3) US6333323B1 (fr)
EP (1) EP1069111A4 (fr)
JP (1) JP3794469B2 (fr)
KR (1) KR20010041705A (fr)
CN (1) CN1142909C (fr)
AU (1) AU752005B2 (fr)
BR (1) BR9909146A (fr)
CA (1) CA2326166A1 (fr)
HU (1) HUP0103460A3 (fr)
ID (1) ID26031A (fr)
IL (1) IL137974A0 (fr)
NO (1) NO317423B1 (fr)
NZ (1) NZ506435A (fr)
PL (1) PL343249A1 (fr)
RU (1) RU2217421C2 (fr)
WO (1) WO1999050245A1 (fr)
ZA (1) ZA200004047B (fr)

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CA2333771A1 (fr) * 1998-06-03 1999-12-09 Mark W. Embrey Inhibiteurs de vih integrase
ID29027A (id) 1998-12-25 2001-07-26 Shionogi & Co Turunan-turunan heteroaromatik yang mempunyai aktivitas penghambatan terhadap integrase hiv
US7294481B1 (en) * 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
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ATE504572T1 (de) * 1999-09-02 2011-04-15 Shionogi & Co Derivate von aromatische heterocyclen enthaltende integraseinhibitoren
BR0111678A (pt) * 2000-06-13 2003-06-03 Shionogi & Co Composições medicinais contendo derivados de propenona
EP1297834A4 (fr) * 2000-06-14 2007-05-09 Shionogi & Co Inhibiteur d'enzymes possedant deux ions metal divalents en tant que centres actifs
DK1341414T3 (da) * 2000-11-16 2013-03-25 Univ California Marint actinomycet-taxon til opdagelse af medikamenter og fermenteringsprodukter
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CA2333771A1 (fr) 1998-06-03 1999-12-09 Mark W. Embrey Inhibiteurs de vih integrase
CA2329134A1 (fr) 1998-06-03 1999-12-09 David L. Clark Inhibiteurs de vih integrase
CA2333707A1 (fr) 1998-06-03 1999-12-09 Melissa Egbertson Inhibiteurs de vih integrase
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Also Published As

Publication number Publication date
CN1142909C (zh) 2004-03-24
HUP0103460A3 (en) 2002-11-28
US6333323B1 (en) 2001-12-25
ZA200004047B (en) 2001-04-25
CN1294580A (zh) 2001-05-09
EP1069111A4 (fr) 2001-06-06
PL343249A1 (en) 2001-07-30
CA2326166A1 (fr) 1999-10-07
US20020019434A1 (en) 2002-02-14
NO20004787L (no) 2000-11-27
ID26031A (id) 2000-11-16
US20030181499A1 (en) 2003-09-25
AU752005B2 (en) 2002-09-05
KR20010041705A (ko) 2001-05-25
RU2217421C2 (ru) 2003-11-27
WO1999050245A1 (fr) 1999-10-07
NZ506435A (en) 2002-08-28
JP3794469B2 (ja) 2006-07-05
BR9909146A (pt) 2000-12-05
EP1069111A1 (fr) 2001-01-17
NO317423B1 (no) 2004-10-25
NO20004787D0 (no) 2000-09-25
US6716605B2 (en) 2004-04-06
AU2958199A (en) 1999-10-18
HUP0103460A2 (hu) 2002-01-28
US6506787B2 (en) 2003-01-14

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