IL136415A - Transmucosal formulations of levosimendan - Google Patents
Transmucosal formulations of levosimendanInfo
- Publication number
- IL136415A IL136415A IL13641598A IL13641598A IL136415A IL 136415 A IL136415 A IL 136415A IL 13641598 A IL13641598 A IL 13641598A IL 13641598 A IL13641598 A IL 13641598A IL 136415 A IL136415 A IL 136415A
- Authority
- IL
- Israel
- Prior art keywords
- levosimendan
- patient
- source
- mucous membrane
- transmucosal formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Luminescent Compositions (AREA)
- Paper (AREA)
- Air Bags (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI974578A FI974578A (fi) | 1997-12-19 | 1997-12-19 | Menetelmä levosimendaanin antamiseksi |
PCT/FI1998/000977 WO1999032081A1 (en) | 1997-12-19 | 1998-12-11 | Transmucosal formulations of levosimendan |
Publications (2)
Publication Number | Publication Date |
---|---|
IL136415A0 IL136415A0 (en) | 2001-06-14 |
IL136415A true IL136415A (en) | 2005-03-20 |
Family
ID=8550178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13641598A IL136415A (en) | 1997-12-19 | 1998-12-11 | Transmucosal formulations of levosimendan |
Country Status (26)
Country | Link |
---|---|
US (1) | US6399610B1 (de) |
EP (1) | EP1052973B1 (de) |
JP (1) | JP2001526205A (de) |
KR (1) | KR100753689B1 (de) |
AT (1) | ATE215358T1 (de) |
AU (1) | AU738082B2 (de) |
BR (1) | BR9813641A (de) |
CA (1) | CA2313618C (de) |
CZ (1) | CZ296693B6 (de) |
DE (1) | DE69804678T2 (de) |
DK (1) | DK1052973T3 (de) |
EA (1) | EA002197B1 (de) |
EE (1) | EE04330B1 (de) |
ES (1) | ES2175827T3 (de) |
FI (1) | FI974578A (de) |
HR (1) | HRP20000400B1 (de) |
HU (1) | HU226736B1 (de) |
IL (1) | IL136415A (de) |
NO (1) | NO320050B1 (de) |
NZ (1) | NZ504806A (de) |
PL (1) | PL191868B1 (de) |
PT (1) | PT1052973E (de) |
RS (1) | RS49889B (de) |
SK (1) | SK284838B6 (de) |
WO (1) | WO1999032081A1 (de) |
ZA (1) | ZA9811405B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI980901A (fi) * | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaania säädellysti vapauttavia oraalisia koostumuksia |
FI20002755A0 (fi) | 2000-12-15 | 2000-12-15 | Orion Yhtymae Oyj | Menetelmä erektiilin dysfunktion hoitamiseen |
CN100428937C (zh) * | 2003-10-30 | 2008-10-29 | 北京海合天科技开发有限公司 | 左西孟旦冷冻干燥组合物 |
FI20040674A0 (fi) | 2004-05-12 | 2004-05-12 | Orion Corp | Menetelmä tromboembolisten sairauksien estoon |
JP5577021B2 (ja) | 2005-02-17 | 2014-08-20 | アボット・ラボラトリーズ | 動物における障害を治療および予防するための薬剤組成物の経粘膜投与 |
WO2006087419A2 (en) * | 2005-02-18 | 2006-08-24 | Orion Corporation | A method for administering levosimendan |
WO2007096906A2 (en) * | 2006-02-27 | 2007-08-30 | Panacea Biotec Ltd. | Novel buccoadhesive compositions and process of preparation thereof |
RU2009115720A (ru) | 2006-09-27 | 2010-11-10 | Никоновум Аб (Se) | Направленное применение |
WO2020197918A1 (en) * | 2019-03-22 | 2020-10-01 | Dbbh, Llc | Intranasally administered antihistamines and uses thereof |
EP3993773A1 (de) * | 2019-07-01 | 2022-05-11 | Orion Corporation | Verfahren zur verabreichung (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamid |
AU2020408323A1 (en) | 2019-12-16 | 2022-08-11 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HF-pEF) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2251615B (en) * | 1991-01-03 | 1995-02-08 | Orion Yhtymae Oy | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile |
GB2266841A (en) * | 1992-05-06 | 1993-11-17 | Orion Yhtymae Oy | Compounds for use as anti-ischemic medicaments |
US5688520A (en) * | 1995-03-29 | 1997-11-18 | Minnesota Mining And Manufacturing Company | Transmucosal delivery of melatonin for prevention of migraine |
GB9614098D0 (en) * | 1996-07-05 | 1996-09-04 | Orion Yhtymae Oy | Transdermal delivery of levosimendan |
-
1997
- 1997-12-19 FI FI974578A patent/FI974578A/fi unknown
-
1998
- 1998-12-11 CZ CZ20002155A patent/CZ296693B6/cs not_active IP Right Cessation
- 1998-12-11 BR BR9813641-0A patent/BR9813641A/pt not_active Application Discontinuation
- 1998-12-11 IL IL13641598A patent/IL136415A/xx not_active IP Right Cessation
- 1998-12-11 JP JP2000525076A patent/JP2001526205A/ja active Pending
- 1998-12-11 US US09/581,610 patent/US6399610B1/en not_active Expired - Fee Related
- 1998-12-11 HU HU0100452A patent/HU226736B1/hu not_active IP Right Cessation
- 1998-12-11 PL PL341202A patent/PL191868B1/pl not_active IP Right Cessation
- 1998-12-11 ES ES98959930T patent/ES2175827T3/es not_active Expired - Lifetime
- 1998-12-11 EA EA200000686A patent/EA002197B1/ru not_active IP Right Cessation
- 1998-12-11 DE DE69804678T patent/DE69804678T2/de not_active Expired - Lifetime
- 1998-12-11 WO PCT/FI1998/000977 patent/WO1999032081A1/en active IP Right Grant
- 1998-12-11 DK DK98959930T patent/DK1052973T3/da active
- 1998-12-11 AU AU15656/99A patent/AU738082B2/en not_active Ceased
- 1998-12-11 ZA ZA9811405A patent/ZA9811405B/xx unknown
- 1998-12-11 SK SK906-2000A patent/SK284838B6/sk not_active IP Right Cessation
- 1998-12-11 KR KR1020007006835A patent/KR100753689B1/ko not_active IP Right Cessation
- 1998-12-11 EE EEP200000368A patent/EE04330B1/xx not_active IP Right Cessation
- 1998-12-11 EP EP98959930A patent/EP1052973B1/de not_active Expired - Lifetime
- 1998-12-11 PT PT98959930T patent/PT1052973E/pt unknown
- 1998-12-11 AT AT98959930T patent/ATE215358T1/de not_active IP Right Cessation
- 1998-12-11 RS YUP-369/00A patent/RS49889B/sr unknown
- 1998-12-11 CA CA002313618A patent/CA2313618C/en not_active Expired - Fee Related
- 1998-12-11 NZ NZ504806A patent/NZ504806A/en unknown
-
2000
- 2000-06-14 NO NO20003059A patent/NO320050B1/no not_active IP Right Cessation
- 2000-06-16 HR HR20000400A patent/HRP20000400B1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |