IL133253D0 - Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them - Google Patents

Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL133253D0
IL133253D0 IL13325399A IL13325399A IL133253D0 IL 133253 D0 IL133253 D0 IL 133253D0 IL 13325399 A IL13325399 A IL 13325399A IL 13325399 A IL13325399 A IL 13325399A IL 133253 D0 IL133253 D0 IL 133253D0
Authority
IL
Israel
Prior art keywords
gt
lt
sub
sup
coxr
Prior art date
Application number
IL13325399A
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL13325399A priority Critical patent/IL133253D0/en
Priority claimed from IL14987500A external-priority patent/IL149875D0/en
Publication of IL133253D0 publication Critical patent/IL133253D0/en
Priority claimed from US10/414,007 external-priority patent/US7045117B2/en

Links

Abstract

Novel C-13<SUP>2</SUP>-COXR<SUB>1</SUB>, C-17<SUP>2</SUP>-COXR<SUB>2 </SUB>and C-13<SUP>2</SUP>-COXR<SUB>1</SUB>, C-17<SUP>2</SUP>-COXR<SUB>1 </SUB>derivatives of chlorophyll and bacteriochlorophyll compounds are provided wherein X is O, S or N and R<SUB>1 </SUB>and R<SUB>2</SUB>, the same or different, may be an optionally substituted hydrocarbyl, amino acid, peptide, protein or saccharide radical. The compounds are for use in photodynamic therapy (PDT), for diagnosis of tumors, and for killing cells and infectious agents such as bacteria and virus, both in biological products and in living tissues.
IL13325399A 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them IL133253D0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL13325399A IL133253D0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
IL13325399A IL133253D0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
MXPA02005455A MXPA02005455A (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, and their preparation.
PCT/IL2000/000811 WO2001040232A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, and their preparation
IL14987500A IL149875D0 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
CN 00818603 CN1222526C (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, and their preparation
DK00979916T DK1246826T3 (en) 1999-12-01 2000-12-01 Chlorophyll and bakteriochlorophylestere, their preparation and pharmaceutical compositions comprising these esters
CA 2392989 CA2392989A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
BR0016051A BR0016051A (en) 1999-12-01 2000-12-01 bacterioclorofìlicos chlorophyll and esters, their preparation and pharmaceutical compositions comprising
DE2000623748 DE60023748T2 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyllester, their preparation and pharmaceutical compositions containing them
ES00979916T ES2250214T3 (en) 1999-12-01 2000-12-01 Esters chlorophyll and bacteriochlorophyll, their preparation and pharmaceutical compositions comprising them.
PL00356391A PL356391A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
AT00979916T AT308545T (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyllester, their preparation and pharmaceutical compositions containing them
AU17292/01A AU777761B2 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
US10/148,552 US7169753B2 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
HU0204167A HU224553B1 (en) 1999-12-01 2000-12-01 chlorophyll and bacteriochlorophyll C-133, C-173 diester transesterify
RU2002117287/04A RU2250905C2 (en) 1999-12-01 2000-12-01 Transesterification method for production of synthetic chlorophyll or bacteriochlorophyll derivatives
EP20000979916 EP1246826B1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
JP2001540987A JP2003515538A (en) 1999-12-01 2000-12-01 Esters of chlorophyll and bacteriochlorophyll, their preparation and pharmaceutical compositions containing them
NO20022599A NO323208B1 (en) 1999-12-01 2002-05-31 Omforestringsfremgangsmate for preparing chlorophyll and bacteriochlorophyll-C13 (3), C 17 (3) diesters
US10/414,007 US7045117B2 (en) 1999-12-01 2003-04-16 Method for tumor diagnosis comprising administering of palladium-substituted bacteriochlorophyll derivatives
HK03108847A HK1056557A1 (en) 1999-12-01 2003-12-04 Transesterification process for preparation of synthetic chlorophyll and bacteriochlorophyll derivative

Publications (1)

Publication Number Publication Date
IL133253D0 true IL133253D0 (en) 2001-04-30

Family

ID=11073554

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13325399A IL133253D0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
US (1) US7169753B2 (en)
EP (1) EP1246826B1 (en)
JP (1) JP2003515538A (en)
CN (1) CN1222526C (en)
AT (1) AT308545T (en)
AU (1) AU777761B2 (en)
BR (1) BR0016051A (en)
CA (1) CA2392989A1 (en)
DE (1) DE60023748T2 (en)
DK (1) DK1246826T3 (en)
ES (1) ES2250214T3 (en)
HK (1) HK1056557A1 (en)
HU (1) HU224553B1 (en)
IL (1) IL133253D0 (en)
MX (1) MXPA02005455A (en)
NO (1) NO323208B1 (en)
PL (1) PL356391A1 (en)
RU (1) RU2250905C2 (en)
WO (1) WO2001040232A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
EP1318807A4 (en) * 2000-08-11 2008-02-20 Ceramoptec Gmbh Photosensitizing ointment
EP2401962A1 (en) 2002-05-08 2012-01-04 Yeda Research And Development Co., Ltd. Sensitized online BOLD-MRI imaging method
IL152900D0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
ES2572976T3 (en) 2003-07-31 2016-06-03 Gentlewaves Llc System and method for photodynamic treatment of skin
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Morgan Chun Lam Photodynamic therapy for the treatment of acne
ES2400566T3 (en) 2004-06-09 2013-04-10 Qlt, Inc. Photodynamic therapy for the treatment of overactive sebaceous glands disorders using verteporfin and / or topically applied lemuteporfin
ZA200700169B (en) * 2004-06-07 2008-05-28 Yeda Res & Dev Cationic bacteriochlorophyll derivatives and uses thereof
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
FR2924021B1 (en) * 2007-11-27 2010-08-13 Du Vernet Michele Eymard Composition for skin treatment by photodynamic therapy
WO2009095912A1 (en) * 2008-01-28 2009-08-06 Yeda Research And Development Co. Ltd Endoscopic imaging photodynamic therapy system and methods of use
AU2009219682B2 (en) 2008-02-27 2015-06-18 Yeda Research & Development Co. Ltd RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors
US20130289089A1 (en) 2011-01-13 2013-10-31 Jerome A. Morris Pharmaceutical Compositions for Topical Delivery of Photosensitizers and Uses Thereof
AU2012298156B2 (en) * 2011-08-23 2017-08-17 Yeda Research And Development Co.Ltd. Method for photodynamic therapy of corneal thinning or scleral weakening with bacteriochlorophyll compounds
CN104703624A (en) 2012-07-11 2015-06-10 德米拉股份有限公司 Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
WO2015006429A1 (en) 2013-07-12 2015-01-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
CA3020067A1 (en) * 2016-04-10 2017-10-19 Yeda Research And Development Co. Ltd. Combinational therapies for treatment of cancer comprising a bacteriochlorophyll derivative
CN108191877A (en) * 2018-02-05 2018-06-22 云南瑞宝生物科技股份有限公司 Method for extracting and purifying chlorophyll from silkworm excrement

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171741A (en) 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121867A1 (en) 1991-07-02 1993-01-07 Leifeld & Lemke Maschf Device for testing the tightness of lids with hermetically sealed cups
DE4121876A1 (en) * 1991-07-02 1993-01-14 Scheer Hugo New modified bacterial chlorophyll derivs. - for diagnosis and treatment of tumours
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
IL116126D0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
HU0204167A2 (en) 2003-03-28
AU1729201A (en) 2001-06-12
DE60023748T2 (en) 2006-08-03
CN1222526C (en) 2005-10-12
MXPA02005455A (en) 2002-11-29
US7169753B2 (en) 2007-01-30
RU2250905C2 (en) 2005-04-27
CN1425015A (en) 2003-06-18
BR0016051A (en) 2002-07-23
HU0204167A3 (en) 2004-08-30
NO20022599L (en) 2002-07-11
DK1246826T3 (en) 2006-01-02
HU224553B1 (en) 2005-10-28
EP1246826A1 (en) 2002-10-09
EP1246826B1 (en) 2005-11-02
AU777761B2 (en) 2004-10-28
ES2250214T3 (en) 2006-04-16
US20030148926A1 (en) 2003-08-07
WO2001040232A1 (en) 2001-06-07
NO20022599D0 (en) 2002-05-31
DE60023748D1 (en) 2005-12-08
WO2001040232A9 (en) 2002-09-12
AT308545T (en) 2005-11-15
NO323208B1 (en) 2007-01-22
CA2392989A1 (en) 2001-06-07
HK1056557A1 (en) 2006-09-01
JP2003515538A (en) 2003-05-07
PL356391A1 (en) 2004-06-28

Similar Documents

Publication Publication Date Title
Diamond et al. Photodynamic therapy of malignant tumours
Smetana et al. Treatment of viral infections with 5‐aminolevulinic acid and light
US4929442A (en) Compositions suitable for human topical application including a growth factor and/or related materials
ES2451441T3 (en) Compositions comprising human collagen and elastin and human uses thereof
ES2210808T3 (en) Compositions and their use in preventing adhesion formation in a biological tissue.
US20020041898A1 (en) Novel targeted delivery systems for bioactive agents
JP4726296B2 (en) Matrix protein compositions for wound healing
Yoon et al. Prophylactic effect of Korean mistletoe (Viscum album coloratum) extract on tumor metastasis is mediated by enhancement of NK cell activity
US7268155B2 (en) Photosensitizer conjugates for pathogen targeting
US5059588A (en) Methods and compositions for healing bone using gly his lys: copper
US20030118539A1 (en) Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
RU2368375C2 (en) Antimicrobial erythrosine-based compound for photodynamic therapy and use thereof
ES2242448T3 (en) Methods and compositions for treating cell proliferative disorders.
Ranly Pulpotomy therapy in primary teeth: new modalities for old rationales
EP1198489B1 (en) Combinations for introducing nucleic acids into cells
Laato et al. Stimulation of wound healing by epidermal growth factor. A dose-dependent effect.
TWI238824B (en) 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
Mutsaers et al. Stimulation of mesothelial cell proliferation by exudate macrophages enhances serosal wound healing in a murine model
WO1997042975A3 (en) Chitosan related compositions for delivery of nucleic acids into a cell
JPH10505057A (en) Bioadhesive wound-healing compositions
JP2010505857A (en) Human placental collagen compositions, and methods and methods of use thereof for manufacturing
HU0301452A2 (en) A pharmaceutical composition containing and the use photochemotherapeutic agent and a mucoadhesive agent
BR0113666A (en) Peptidomimetic protease inhibitors
EP2305276A3 (en) Processed lipoaspirate cells for use in therapy
CA2322188A1 (en) The use of fumaric acid derivatives in transplant medicine