IL132239D0 - Humanized antibodies and methods for forming humanized antibodies - Google Patents

Humanized antibodies and methods for forming humanized antibodies

Info

Publication number
IL132239D0
IL132239D0 IL13223998A IL13223998A IL132239D0 IL 132239 D0 IL132239 D0 IL 132239D0 IL 13223998 A IL13223998 A IL 13223998A IL 13223998 A IL13223998 A IL 13223998A IL 132239 D0 IL132239 D0 IL 132239D0
Authority
IL
Israel
Prior art keywords
humanized antibodies
methods
forming
humanized
antibodies
Prior art date
Application number
IL13223998A
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US83350497A priority Critical
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to PCT/US1998/006724 priority patent/WO1998045332A2/en
Publication of IL132239D0 publication Critical patent/IL132239D0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
IL13223998A 1997-04-07 1998-04-03 Humanized antibodies and methods for forming humanized antibodies IL132239D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US83350497A true 1997-04-07 1997-04-07
PCT/US1998/006724 WO1998045332A2 (en) 1997-04-07 1998-04-03 Humanized antibodies and methods for forming humanized antibodies

Publications (1)

Publication Number Publication Date
IL132239D0 true IL132239D0 (en) 2001-03-19

Family

ID=25264594

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13223998A IL132239D0 (en) 1997-04-07 1998-04-03 Humanized antibodies and methods for forming humanized antibodies
IL132240A IL132240A (en) 1997-04-07 1999-10-06 Anti-vegf antibodies
IL175906A IL175906A (en) 1997-04-07 2006-05-24 Anti-vegf antibodies with stronger binding affinity

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL132240A IL132240A (en) 1997-04-07 1999-10-06 Anti-vegf antibodies
IL175906A IL175906A (en) 1997-04-07 2006-05-24 Anti-vegf antibodies with stronger binding affinity

Country Status (22)

Country Link
EP (6) EP0971959B1 (en)
JP (1) JP4191258B2 (en)
KR (2) KR100794454B1 (en)
CN (6) CN101665536B (en)
AT (4) AT541586T (en)
AU (1) AU740738B2 (en)
BR (1) BR9809388B1 (en)
CA (1) CA2286397C (en)
CY (3) CY1111345T1 (en)
DE (3) DE69842174D1 (en)
DK (4) DK0971959T3 (en)
ES (4) ES2349559T3 (en)
GE (1) GEPI20105118B (en)
HK (7) HK1025338A1 (en)
IL (3) IL132239D0 (en)
NO (2) NO325823B1 (en)
NZ (1) NZ500077A (en)
PT (5) PT1787999E (en)
SI (5) SI0971959T1 (en)
TR (1) TR199902818T2 (en)
WO (1) WO1998045332A2 (en)
ZA (2) ZA9802907B (en)

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* Cited by examiner, † Cited by third party
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