IL127446D0 - Compositions and methods for coating medical devices - Google Patents

Compositions and methods for coating medical devices

Info

Publication number
IL127446D0
IL127446D0 IL12744697A IL12744697A IL127446D0 IL 127446 D0 IL127446 D0 IL 127446D0 IL 12744697 A IL12744697 A IL 12744697A IL 12744697 A IL12744697 A IL 12744697A IL 127446 D0 IL127446 D0 IL 127446D0
Authority
IL
Israel
Prior art keywords
compositions
methods
medical devices
coating medical
coating
Prior art date
Application number
IL12744697A
Other versions
IL127446A (en
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US08/662,341 priority Critical patent/US6143037A/en
Application filed by Univ Michigan filed Critical Univ Michigan
Priority to PCT/US1997/010079 priority patent/WO1997047254A1/en
Publication of IL127446D0 publication Critical patent/IL127446D0/en
Priority claimed from IL15337402A external-priority patent/IL153374D0/en
Publication of IL127446A publication Critical patent/IL127446A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14Post-treatment to improve physical properties
    • A61L17/145Coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Threaded wires, pins or screws; Nuts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A61F2002/30064Coating or prosthesis-covering structure made of biodegradable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3084Nanostructures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00017Iron- or Fe-based alloys, e.g. stainless steel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00023Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/0097Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622Microcapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/624Nanocapsules
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/84Manufacture, treatment, or detection of nanostructure
    • Y10S977/89Deposition of materials, e.g. coating, cvd, or ald
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915Therapeutic or pharmaceutical composition
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/931Medical device coating
IL12744697A 1996-06-12 1997-06-11 Compositions and methods for coating medical devices IL127446A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US08/662,341 US6143037A (en) 1996-06-12 1996-06-12 Compositions and methods for coating medical devices
PCT/US1997/010079 WO1997047254A1 (en) 1996-06-12 1997-06-11 Compositions and methods for coating medical devices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15337402A IL153374D0 (en) 1996-06-12 2002-12-11 Compositions and methods for coating medical devices

Publications (2)

Publication Number Publication Date
IL127446D0 true IL127446D0 (en) 1999-10-28
IL127446A IL127446A (en) 2003-07-06

Family

ID=24657324

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15337497A IL153374A (en) 1996-06-12 1997-06-11 Compositions and methods for coating medical devices
IL12744697A IL127446A (en) 1996-06-12 1997-06-11 Compositions and methods for coating medical devices

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL15337497A IL153374A (en) 1996-06-12 1997-06-11 Compositions and methods for coating medical devices

Country Status (7)

Country Link
US (2) US6143037A (en)
EP (1) EP0910301A4 (en)
JP (2) JP2000512519A (en)
AU (1) AU715339B2 (en)
CA (1) CA2257976C (en)
IL (2) IL153374A (en)
WO (1) WO1997047254A1 (en)

Families Citing this family (281)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6464999B1 (en) * 1998-06-17 2002-10-15 Galt Incorporated Bioadhesive medical devices
US6387700B1 (en) 1996-11-04 2002-05-14 The Reagents Of The University Of Michigan Cationic peptides, Cys-Trp-(LYS)n, for gene delivery
GB2325934A (en) * 1997-06-03 1998-12-09 Polybiomed Ltd Treating metal surfaces to enhance bio-compatibility and/or physical characteristics
US6433154B1 (en) * 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
IL134696D0 (en) * 1997-08-26 2001-04-30 Technion Res & Dev Foundation Intravascular apparatus and method
US6775574B1 (en) * 1997-11-07 2004-08-10 Medtronic, Inc. Method and system for myocardial infarction repair
US6682724B2 (en) 1999-02-23 2004-01-27 Arch Chemcials, Inc. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
US6465015B1 (en) * 1998-02-24 2002-10-15 Arch Chemicals, Inc. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
US6395253B2 (en) 1998-04-23 2002-05-28 The Regents Of The University Of Michigan Microspheres containing condensed polyanionic bioactive agents and methods for their production
DE69942348D1 (en) * 1998-04-27 2010-06-17 Surmodics Inc Bioactive agents releasing coatings
US7427602B1 (en) 1998-05-13 2008-09-23 The Regents Of The University Of Michigan Sustained DNA delivery from structural matrices
AU753270B2 (en) * 1998-05-21 2002-10-10 Isis Pharmaceuticals, Inc. Compositions and methods for topical delivery of oligonucleotides
FR2779340B1 (en) * 1998-06-04 2000-12-29 Delab An implantable intraluminal device
US6627209B2 (en) * 1998-08-03 2003-09-30 W. Jerry Easterling Surgical stent and method for preventing occlusion of stented vessels and conduits after implantation of stents
EP1112095B1 (en) 1998-09-11 2002-11-20 Michael Raschke Biologically active implants
US20030099682A1 (en) * 1998-11-20 2003-05-29 Francis Moussy Apparatus and method for control of tissue/implant interactions
US6540780B1 (en) 1998-11-23 2003-04-01 Medtronic, Inc. Porous synthetic vascular grafts with oriented ingrowth channels
WO2000043044A1 (en) * 1999-01-19 2000-07-27 The Children's Hospital Of Philadelphia Compositions and methods for controlled delivery of virus vectors
US6541022B1 (en) * 1999-03-19 2003-04-01 The Regents Of The University Of Michigan Mineral and cellular patterning on biomaterial surfaces
US6767928B1 (en) * 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
AT244558T (en) * 1999-04-16 2003-07-15 Novo Nordisk As Dry moldable drug formulation
US6469132B1 (en) * 1999-05-05 2002-10-22 Mcgill University Diblock copolymer and use thereof in a micellar drug delivery system
RU2245722C2 (en) * 1999-06-22 2005-02-10 Рисерч Дивелопмент Фаундейшн Advanced wound cover for improving wound healing
AU730929B2 (en) * 1999-07-06 2001-03-22 Nestec S.A. Composition and method for prolonging the useful life of enteral feeding tubes
US6770740B1 (en) 1999-07-13 2004-08-03 The Regents Of The University Of Michigan Crosslinked DNA condensate compositions and gene delivery methods
US6554857B1 (en) * 1999-07-20 2003-04-29 Medtronic, Inc Transmural concentric multilayer ingrowth matrix within well-defined porosity
US6702848B1 (en) 1999-07-20 2004-03-09 Peter Paul Zilla Foam-type vascular prosthesis with well-defined anclio-permissive open porosity
JP2003508185A (en) * 1999-08-03 2003-03-04 スミス アンド ネフュー インコーポレーテッド Implantable controlled release device
US7807211B2 (en) 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US20020006664A1 (en) * 1999-09-17 2002-01-17 Sabatini David M. Arrayed transfection method and uses related thereto
US9616150B2 (en) * 1999-10-29 2017-04-11 Children's Hospital Los Angeles Bone hemostasis method and materials
US7109024B2 (en) * 1999-11-15 2006-09-19 Dr. Chip Biotechnology Inc. Biomolecule-bound substrates
US6887842B1 (en) * 1999-11-19 2005-05-03 The Board Of Trustees Of The Leland Stanford Junior University Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
US7838007B2 (en) * 1999-12-07 2010-11-23 Allergan, Inc. Methods for treating mammary gland disorders
CA2400172C (en) 2000-02-28 2010-04-20 Genesegues, Inc. Nanocapsule encapsulation system and method
ES2283398T3 (en) * 2000-03-15 2007-11-01 Orbusneich Medical, Inc. Coating improves the adhesion of endothelial cells.
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
WO2001087491A1 (en) 2000-05-16 2001-11-22 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
DE10025803A1 (en) * 2000-05-24 2001-12-20 Jms Co Ltd Polymer surface with biologically active properties and processes for their preparation
EP1303256B1 (en) * 2000-06-09 2009-01-07 Baylor College of Medicine The combination of antimicrobial agents and bacterial interference to coat medical devices
WO2002005744A1 (en) * 2000-07-14 2002-01-24 Novo Nordisk A/S Method of moulding a pharmaceutical composition in a packaging material
US6669959B1 (en) * 2000-07-18 2003-12-30 Aeropharm Technology Incorporated Modulated release particles for lung delivery
JP2002035109A (en) * 2000-07-21 2002-02-05 Tadashi Kokubo Anti-thrombotic material and method for manufacturing the same
AU2001297823B2 (en) 2000-10-26 2005-05-12 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
US20040241211A9 (en) * 2000-11-06 2004-12-02 Fischell Robert E. Devices and methods for reducing scar tissue formation
US6534693B2 (en) * 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
AU2705202A (en) 2000-11-30 2002-06-11 Univ Florida Treatments for neurogenetic disorders, impulse control disorders, and wound healing
US6812217B2 (en) * 2000-12-04 2004-11-02 Medtronic, Inc. Medical device and methods of use
DE10113108B4 (en) * 2001-03-15 2007-07-26 Dot Gmbh Active ingredient-containing calcium phosphate materials
WO2002076287A2 (en) * 2001-03-26 2002-10-03 Tyco Healthcare Group Lp Oil coated sutures
US6656506B1 (en) 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
GB0113697D0 (en) * 2001-06-06 2001-07-25 Smith & Nephew Fixation devices for tissue repair
US7544670B2 (en) 2001-06-14 2009-06-09 The Regents Of The University Of California HoxD3, HoxA3 and HoxB3 compositions and methods for improved wound healing
WO2002102982A2 (en) * 2001-06-14 2002-12-27 Regents Of The University Of California Hoxd3 compositions ad methods for improved wound healing
US20060263401A1 (en) * 2001-07-13 2006-11-23 Flow Focusing, Inc. Formulation and Method for Preventing Infection
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
US20040142013A1 (en) * 2001-07-13 2004-07-22 Flow Focusing, Inc. Implantable orthopedic surgical devices with controlled release antimicrobial component
US6913626B2 (en) * 2001-08-14 2005-07-05 Mcghan Jim J. Medical implant having bioabsorbable textured surface
EP1434571B1 (en) * 2001-10-05 2005-05-11 SurModics, Inc. Particle immobilized coatings and uses thereof
US8679454B2 (en) * 2001-10-05 2014-03-25 Surmodics, Inc. Particle immobilized coatings and uses thereof
US20090254129A1 (en) * 2007-04-30 2009-10-08 Kishore Tipirneni Bone screw system and method for the fixation of bone fractures
US8679167B2 (en) 2001-10-18 2014-03-25 Orthoip, Llc System and method for a cap used in the fixation of bone fractures
US20090048606A1 (en) * 2001-10-18 2009-02-19 Fxdevices Llc Guide system and method for the fixation of bone fractures
US20080243191A1 (en) * 2001-10-18 2008-10-02 Fx Devices, Llc Adjustable bone plate fixation system and metho
US20110034925A1 (en) * 2001-10-18 2011-02-10 Orthoip, Llc Lagwire system and method for the fixation of bone fractures
US20090131991A1 (en) * 2001-10-18 2009-05-21 Kishore Tipirneni System and method for the fixation of bone fractures
US20090131990A1 (en) * 2001-10-18 2009-05-21 Kishore Tipirneni Bone screw system and method
US9060809B2 (en) 2001-10-18 2015-06-23 Orthoip, Llc Lagwire system and method for the fixation of bone fractures
US8702768B2 (en) 2001-10-18 2014-04-22 Orthoip, Llc Cannulated bone screw system and method
US8828067B2 (en) 2001-10-18 2014-09-09 Orthoip, Llc Bone screw system and method
US20100268285A1 (en) * 2001-10-18 2010-10-21 Orthoip, Llc Bone screw system and method for the fixation of bone fractures
US6736819B2 (en) * 2001-10-18 2004-05-18 Kishore Tipirneni System and method for fixation of bone fractures
US6517889B1 (en) 2001-11-26 2003-02-11 Swaminathan Jayaraman Process for coating a surface of a stent
US6641611B2 (en) 2001-11-26 2003-11-04 Swaminathan Jayaraman Therapeutic coating for an intravascular implant
US8454997B2 (en) 2001-12-18 2013-06-04 Novo Nordisk A/S Solid dose micro implant
EP1467661A4 (en) 2001-12-19 2008-11-05 Nmt Medical Inc Septal occluder and associated methods
US7318833B2 (en) 2001-12-19 2008-01-15 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
EP1486561B1 (en) * 2001-12-26 2013-12-04 Canon Kabushiki Kaisha Probe medium
US20030139819A1 (en) * 2002-01-18 2003-07-24 Beer Nicholas De Method and apparatus for closing septal defects
US8529961B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
AU2003220502A1 (en) 2002-03-25 2003-10-13 Nmt Medical, Inc. Patent foramen ovale (pfo) closure clips
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
ES2369640T3 (en) * 2002-05-24 2011-12-02 Angiotech International Ag Compositions and methods for coating medical implants.
CA2486919C (en) 2002-06-03 2011-03-15 Nmt Medical, Inc. Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
CA2488337A1 (en) 2002-06-05 2003-12-18 Nmt Medical, Inc. Patent foramen ovale (pfo) closure device with radial and circumferential support
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
CA2497349C (en) * 2002-09-26 2008-07-08 Angiotech International Ag Perivascular wraps
GB2393655B (en) * 2002-09-27 2005-08-24 Johnson & Johnson Medical Ltd Wound treatment device
US7766820B2 (en) 2002-10-25 2010-08-03 Nmt Medical, Inc. Expandable sheath tubing
US8034361B2 (en) * 2002-11-12 2011-10-11 Advanced Cardiovascular Systems, Inc. Stent coatings incorporating nanoparticles
US7491234B2 (en) 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
AU2003294682A1 (en) 2002-12-09 2004-06-30 Nmt Medical, Inc. Septal closure devices
WO2004071451A2 (en) * 2003-02-12 2004-08-26 Ceremed, Inc. Random alkylene oxide copolymers for medical and surgical utilities
US8715771B2 (en) * 2003-02-26 2014-05-06 Abbott Cardiovascular Systems Inc. Coated stent and method of making the same
US7255891B1 (en) * 2003-02-26 2007-08-14 Advanced Cardiovascular Systems, Inc. Method for coating implantable medical devices
US7658747B2 (en) 2003-03-12 2010-02-09 Nmt Medical, Inc. Medical device for manipulation of a medical implant
WO2004098565A2 (en) 2003-05-02 2004-11-18 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
US8480706B2 (en) 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
ES2428967T3 (en) 2003-07-14 2013-11-12 W.L. Gore & Associates, Inc. tubular closure device patent foramen ovale (PFO) retention system
US7169404B2 (en) 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US20050037047A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices comprising spray dried microparticles
CA2536368A1 (en) 2003-08-19 2005-03-03 Nmt Medical, Inc. Expandable sheath tubing
US7807722B2 (en) * 2003-11-26 2010-10-05 Advanced Cardiovascular Systems, Inc. Biobeneficial coating compositions and methods of making and using thereof
USRE45744E1 (en) 2003-12-01 2015-10-13 Abbott Cardiovascular Systems Inc. Temperature controlled crimping
US20050273119A1 (en) 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
US20050192626A1 (en) 2004-01-30 2005-09-01 Nmt Medical, Inc. Devices, systems, and methods for closure of cardiac openings
US7871419B2 (en) 2004-03-03 2011-01-18 Nmt Medical, Inc. Delivery/recovery system for septal occluder
US20050220853A1 (en) * 2004-04-02 2005-10-06 Kinh-Luan Dao Controlled delivery of therapeutic agents from medical articles
US20050267524A1 (en) 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
CN101027045A (en) * 2004-04-13 2007-08-29 阿尔扎公司 Apparatus and method for transdermal delivery of fentanyl-based agents
US8361110B2 (en) 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US8308760B2 (en) 2004-05-06 2012-11-13 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US7842053B2 (en) 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
CA2563298A1 (en) 2004-05-07 2005-11-24 Nmt Medical, Inc. Catching mechanisms for tubular septal occluder
US7704268B2 (en) 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
JP2008507341A (en) * 2004-07-21 2008-03-13 メドトロニック,インコーポレイティド Medical devices and methods for reducing localized fibrosis
US20060030538A1 (en) * 2004-07-21 2006-02-09 Medtronic, Inc. Methods for reducing or preventing localized fibrosis using SiRNA
US8980300B2 (en) 2004-08-05 2015-03-17 Advanced Cardiovascular Systems, Inc. Plasticizers for coating compositions
CA2578478A1 (en) * 2004-08-06 2006-02-16 National Jewish Medical And Research Center Product and process for inhibition of biofilm development
US20060057216A1 (en) * 2004-09-15 2006-03-16 Salamone Joseph C Low-obscuration image transmitting particulate ocular therapeutic formulations
US20060057215A1 (en) * 2004-09-15 2006-03-16 Raiche Adrian T Method for the production of nanoparticles and microparticles by ternary agent concentration and temperature alteration induced immiscibility
US7495052B2 (en) * 2004-09-15 2009-02-24 Bausch & Lomb Incorporated Method for the production of polymerized nanoparticles and microparticles by ternary agent concentration and temperature alteration induced immiscibility
CA2581677C (en) 2004-09-24 2014-07-29 Nmt Medical, Inc. Occluder device double securement system for delivery/recovery of such occluder device
EP1807092B1 (en) 2004-11-05 2016-09-07 The Children's Hospital of Philadelphia Biodegradable linkers for molecular therapies
US8263105B2 (en) * 2004-12-01 2012-09-11 Tyco Healthcare Group Lp Biomaterial drug delivery and surface modification compositions
CA2526541C (en) * 2004-12-01 2013-09-03 Tyco Healthcare Group Lp Novel biomaterial drug delivery and surface modification compositions
US20090191254A1 (en) * 2004-12-06 2009-07-30 The Govt. Of The U.S.A., Centers For Disease Control And Prevention Inhibition of biofilm formation using bacteriophage
US20060124466A1 (en) * 2004-12-09 2006-06-15 Scimed Life Systems, Inc. Method and apparatus for coating a medical device by electroplating
AU2006220567A1 (en) * 2005-03-07 2006-09-14 The Regents Of The University Of California Medical implants
US8277480B2 (en) 2005-03-18 2012-10-02 W.L. Gore & Associates, Inc. Catch member for PFO occluder
EP1888510A4 (en) 2005-05-27 2013-01-16 Univ North Carolina Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
AU2006270221B2 (en) 2005-07-15 2012-01-19 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
CA2617940A1 (en) * 2005-08-05 2007-02-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) Materials useful for support and/or replacement of tissue and the use thereof for making prostheses
US9259267B2 (en) 2005-09-06 2016-02-16 W.L. Gore & Associates, Inc. Devices and methods for treating cardiac tissue
WO2007030433A2 (en) 2005-09-06 2007-03-15 Nmt Medical, Inc. Removable intracardiac rf device
US20070087059A1 (en) * 2005-10-17 2007-04-19 Frank Everaerts Bioactive delivery matrix compositions and methods
CN1962155A (en) * 2005-11-10 2007-05-16 鸿富锦精密工业(深圳)有限公司 CO2 laser welding apparatus
CN101340935B (en) 2005-11-14 2013-05-08 拜奥美特3i有限责任公司 Deposition of discrete nanoparticles on an implant surface
US20070134191A1 (en) * 2005-12-14 2007-06-14 L'oreal Hair styling compositions containing a nonionic amphiphilic polymer in combination with styling polymers and emulsifying agents
EP1962695A1 (en) 2005-12-22 2008-09-03 NMT Medical, Inc. Catch members for occluder devices
WO2007084418A2 (en) * 2006-01-13 2007-07-26 Surmodics, Inc. Microparticle containing matrices for drug delivery
CA2637883C (en) 2006-01-31 2015-07-07 Regents Of The University Of Minnesota Electrospray coating of objects
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
CA2641117C (en) 2006-01-31 2018-01-02 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US8591531B2 (en) 2006-02-08 2013-11-26 Tyrx, Inc. Mesh pouches for implantable medical devices
AU2007344645B2 (en) 2006-02-08 2012-12-13 Tyrx, Inc. Temporarily stiffened mesh prostheses
US8315700B2 (en) 2006-02-08 2012-11-20 Tyrx, Inc. Preventing biofilm formation on implantable medical devices
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
CA2647505C (en) 2006-03-31 2014-07-29 Nmt Medical, Inc. Deformable flap catch mechanism for occluder device
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
WO2007127363A2 (en) 2006-04-26 2007-11-08 Micell Technologies, Inc. Coatings containing multiple drugs
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
JP2009542671A (en) * 2006-06-28 2009-12-03 サーモディクス,インコーポレイティド Active agent elution matrix containing fine particles
US20100215708A1 (en) * 2006-06-29 2010-08-26 Andreas Zumbuehl Coating of devices with effector compounds
US7846361B2 (en) 2006-07-20 2010-12-07 Orbusneich Medical, Inc. Bioabsorbable polymeric composition for a medical device
CN103494661B (en) 2006-07-20 2016-03-30 奥巴斯尼茨医学公司 Bioabsorbable polymeric medical
US8460362B2 (en) * 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
US20110130822A1 (en) * 2007-07-20 2011-06-02 Orbusneich Medical, Inc. Bioabsorbable Polymeric Compositions and Medical Devices
DE102006038240A1 (en) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag A process for producing a composite from oligo- or polynucleotides and hydrophobic biodegradable polymers and obtained by the method composite
US20080249633A1 (en) * 2006-08-22 2008-10-09 Tim Wu Biodegradable Materials and Methods of Use
US8636767B2 (en) * 2006-10-02 2014-01-28 Micell Technologies, Inc. Surgical sutures having increased strength
US7959942B2 (en) * 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
EP2073754A4 (en) * 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioabsorbable polymeric composition and medical device background
EP2086599A4 (en) 2006-10-20 2012-11-28 Orbusneich Medical Inc Bioabsorbable medical device with coating
CA2667228C (en) 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
US7972648B2 (en) 2006-10-24 2011-07-05 Biomet 3I, Llc Deposition of discrete nanoparticles on a nanostructured surface of an implant
CA2668130A1 (en) * 2006-11-03 2008-06-05 Boston Scientific Limited Stents with drug eluting coatings
AU2007352548B2 (en) * 2006-11-06 2012-11-15 Tyrx, Inc. Resorbable pouches for implantable medical devices
US9023114B2 (en) 2006-11-06 2015-05-05 Tyrx, Inc. Resorbable pouches for implantable medical devices
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US20080175887A1 (en) * 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9040816B2 (en) 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
US9737642B2 (en) 2007-01-08 2017-08-22 Micell Technologies, Inc. Stents having biodegradable layers
CA2713977A1 (en) * 2007-02-15 2008-08-21 National Jewish Medical And Research Center Methods and compositions for the disruption of biofilms
WO2008115978A2 (en) * 2007-03-20 2008-09-25 University Of Florida Research Foundation, Inc. Polymer with ability to signal the recruitment of vascular progenitor cells
MX2009010396A (en) * 2007-03-29 2009-12-02 Tyrx Pharma Inc Biodegradable, polymer coverings for breast implants.
US8178483B2 (en) * 2007-03-30 2012-05-15 Colgate-Palmolive Company Polymeric encapsulates having a quaternary ammonium salt and methods for producing the same
WO2008124603A1 (en) 2007-04-05 2008-10-16 Nmt Medical, Inc. Septal closure device with centering mechanism
JP5443336B2 (en) * 2007-04-17 2014-03-19 ミセル テクノロジーズ、インコーポレイテッド Stent with a biodegradable layer
WO2008131167A1 (en) 2007-04-18 2008-10-30 Nmt Medical, Inc. Flexible catheter system
US8309222B2 (en) * 2007-04-25 2012-11-13 Covidien Lp Coated filaments
US20100069957A1 (en) * 2007-04-25 2010-03-18 Ferass Abuzaina Coated Filaments
WO2008148013A1 (en) 2007-05-25 2008-12-04 Micell Technologies, Inc. Polymer films for medical device coating
US8802184B2 (en) 2007-05-30 2014-08-12 Abbott Cardiovascular Systems Inc. Medical devices containing biobeneficial particles
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US8048441B2 (en) * 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US8865216B2 (en) * 2007-08-03 2014-10-21 National Institutes Of Health (Nih) Surface-modified nanoparticles for intracellular delivery of therapeutic agents and composition for making same
US20090041727A1 (en) * 2007-08-08 2009-02-12 Conjugon, Inc. Compositions and Methods for Microbe Storage and Delivery
US20110230973A1 (en) * 2007-10-10 2011-09-22 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US8608049B2 (en) * 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
EP2997985A1 (en) 2007-10-30 2016-03-23 Nanyang Technological University A non-biodegradable stent comprising a biodegradable coating and method of coating the same
US8642062B2 (en) 2007-10-31 2014-02-04 Abbott Cardiovascular Systems Inc. Implantable device having a slow dissolving polymer
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
US20090187256A1 (en) * 2008-01-21 2009-07-23 Zimmer, Inc. Method for forming an integral porous region in a cast implant
JP5806466B2 (en) 2008-01-28 2015-11-10 バイオメット・3アイ・エルエルシー Implant surface with improved hydrophilic
US20090198286A1 (en) * 2008-02-05 2009-08-06 Zimmer, Inc. Bone fracture fixation system
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
US8951545B2 (en) * 2008-03-28 2015-02-10 Surmodics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
JP5608160B2 (en) 2008-04-17 2014-10-15 ミセル テクノロジーズ、インコーポレイテッド Stent with a bioabsorbable layer
US20090285873A1 (en) * 2008-04-18 2009-11-19 Abbott Cardiovascular Systems Inc. Implantable medical devices and coatings therefor comprising block copolymers of poly(ethylene glycol) and a poly(lactide-glycolide)
US8916188B2 (en) * 2008-04-18 2014-12-23 Abbott Cardiovascular Systems Inc. Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
US8496954B2 (en) * 2008-04-18 2013-07-30 Surmodics, Inc. Coating systems for the controlled delivery of hydrophilic bioactive agents
US8661630B2 (en) * 2008-05-21 2014-03-04 Abbott Cardiovascular Systems Inc. Coating comprising an amorphous primer layer and a semi-crystalline reservoir layer
US8697113B2 (en) 2008-05-21 2014-04-15 Abbott Cardiovascular Systems Inc. Coating comprising a terpolymer comprising caprolactone and glycolide
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
EP2313122B1 (en) 2008-07-17 2019-03-06 Micell Technologies, Inc. Drug delivery medical device
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
US9295820B2 (en) 2008-08-14 2016-03-29 Surmodics, Inc. Method and apparatus for coating balloon catheters
US8430055B2 (en) 2008-08-29 2013-04-30 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
FR2936709B1 (en) * 2008-10-02 2012-05-11 Ethypharm Sa Tablets alcohol-resistant.
WO2010042854A1 (en) * 2008-10-10 2010-04-15 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
US20100093946A1 (en) * 2008-10-11 2010-04-15 Orbusneich Medical, Inc. Bioabsorbable Polymeric Compositions and Medical Devices
US20100098733A1 (en) * 2008-10-16 2010-04-22 Novan, Inc. Nitric oxide releasing particles for oral care applications
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
CA2757276C (en) 2009-04-01 2017-06-06 Micell Technologies, Inc. Coated stents
CA2759015C (en) 2009-04-17 2017-06-20 James B. Mcclain Stents having controlled elution
US8697110B2 (en) 2009-05-14 2014-04-15 Abbott Cardiovascular Systems Inc. Polymers comprising amorphous terpolymers and semicrystalline blocks
KR101026513B1 (en) 2009-08-14 2011-04-01 한국과학기술원 A Modified Solid Substrate Using Hydroxybenzene-Amine and a Method of modifying the Surface of a Solid Substrate Using the Same
BR112012003792A2 (en) 2009-08-21 2016-04-19 Novan Inc topical gel, and use of the topical gel.
EP2467173B1 (en) 2009-08-21 2019-04-24 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
BR112012008508A2 (en) * 2009-10-13 2017-06-13 Novan Inc Sol-gel coating substrate, a method for producing sol-gel coating
US9295456B2 (en) 2010-02-05 2016-03-29 Nanyang Technological University Occlusion device for closing anatomical defects
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2797792C (en) 2010-04-29 2018-02-27 Isis Pharmaceuticals, Inc. Modulation of transthyretin expression
US20110293690A1 (en) * 2010-05-27 2011-12-01 Tyco Healthcare Group Lp Biodegradable Polymer Encapsulated Microsphere Particulate Film and Method of Making Thereof
WO2012003293A1 (en) 2010-06-30 2012-01-05 Surmodics, Inc. Lipid coating for medical devices delivering bioactive agent
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
US9585988B2 (en) 2010-11-12 2017-03-07 Tyrx, Inc. Anchorage devices comprising an active pharmaceutical ingredient
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (en) 2011-02-28 2019-01-02 Novan Inc Silica particles modified with S-nitrosothiol that release nitric oxide and methods of manufacturing them
FR2972626B1 (en) 2011-03-16 2014-04-11 Sofradim Production Prosthesis comprising a knitted spacer fabric and openwork
US20140301971A1 (en) * 2011-06-21 2014-10-09 Michael T. Milbocker Medical Device Comprising Boswellic Acid
FR2977790B1 (en) 2011-07-13 2013-07-19 Sofradim Production Prosthesis for umbilical hernia
FR2977789B1 (en) 2011-07-13 2013-07-19 Sofradim Production Prosthesis for umbilical hernia
WO2013012689A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
US9526603B2 (en) 2011-09-30 2016-12-27 Covidien Lp Reversible stiffening of light weight mesh
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
FR2985170B1 (en) 2011-12-29 2014-01-24 Sofradim Production Prosthesis for inguinal hernia
FR2985271B1 (en) 2011-12-29 2014-01-24 Sofradim Production Tricot pins
US9131995B2 (en) 2012-03-20 2015-09-15 Biomet 3I, Llc Surface treatment for an implant surface
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
US9308355B2 (en) 2012-06-01 2016-04-12 Surmodies, Inc. Apparatus and methods for coating medical devices
FR2995778B1 (en) 2012-09-25 2015-06-26 Sofradim Production reinforcement prosthesis of the abdominal wall and method of manufacture
FR2995788B1 (en) 2012-09-25 2014-09-26 Sofradim Production Hemostatic patch and method of preparation
FR2995779B1 (en) 2012-09-25 2015-09-25 Sofradim Production Prothese including a mesh and a consolidation means
CA2880380A1 (en) 2012-09-28 2014-04-03 Sofradim Production Packaging for a hernia repair device
WO2014120092A1 (en) 2013-02-01 2014-08-07 Nanyang Technological University A device and method for forming an anastomotic joint between two parts of a body
US9951374B2 (en) 2013-02-19 2018-04-24 Wisconsin Alumni Research Foundation Enhanced throughput mineral coatings for optimization of stem cell behavior
KR20180059584A (en) 2013-05-15 2018-06-04 미셀 테크놀로지즈, 인코포레이티드 Bioabsorbable biomedical implants
FR3006581B1 (en) 2013-06-07 2016-07-22 Sofradim Production Denture base has a fabric for laparoscopically
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
EP3000432A1 (en) 2014-09-29 2016-03-30 Sofradim Production Textile-based prosthesis for treatment of inguinal hernia
EP3029189A1 (en) 2014-12-05 2016-06-08 Sofradim Production Prosthetic porous knit, method of making same and hernia prosthesis
EP3059255A1 (en) 2015-02-17 2016-08-24 Sofradim Production Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
EP3085337A1 (en) 2015-04-24 2016-10-26 Sofradim Production Prosthesis for supporting a breast structure
CN104984386A (en) * 2015-07-20 2015-10-21 太原理工大学 Method for preparing medicine-carrying polylactic acid surgical sutures

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL290280A (en) * 1962-03-15
US3557795A (en) * 1968-06-19 1971-01-26 Weck & Co Inc Edward Suture provided with wound healing coating
US3839297A (en) * 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US4024871A (en) * 1975-07-23 1977-05-24 Ethicon, Inc. Antimicrobial sutures
CH653558A5 (en) * 1979-11-23 1986-01-15 Battelle Memorial Institute suture provided with a protective sleeve.
US4534958A (en) * 1983-07-13 1985-08-13 Basf Wyandotte Corporation Aerosol gel
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4532929A (en) * 1984-07-23 1985-08-06 Ethicon, Inc. Dry coating of surgical filaments
DE3678308D1 (en) * 1985-02-07 1991-05-02 Takeda Chemical Industries Ltd A process for the preparation of microcapsules.
US5225279A (en) * 1985-04-30 1993-07-06 Rohm And Haas Company Solvent core encapsulant composition
US4649920A (en) * 1986-01-30 1987-03-17 Pfizer Hospital Products Group, Inc. Coated suture
US5032638A (en) * 1986-09-05 1991-07-16 American Cyanamid Company Bioabsorbable coating for a surgical device
US4711241A (en) * 1986-09-05 1987-12-08 American Cyanamid Company Surgical filament coating
US4857602A (en) * 1986-09-05 1989-08-15 American Cyanamid Company Bioabsorbable surgical suture coating
JPH0555152B2 (en) * 1986-11-21 1993-08-16 Terumo Corp
DE3786927D1 (en) * 1986-12-03 1993-09-09 Terumo Corp Antithrombotic drug and its production.
JPH034228B2 (en) * 1987-02-19 1991-01-22 Nippon Medeikaru Sapurai Kk
US4968350A (en) * 1987-04-16 1990-11-06 Christian Bindschaedler Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof
US5306289A (en) * 1987-08-26 1994-04-26 United States Surgical Corporation Braided suture of improved characteristics
US5123912A (en) * 1987-08-26 1992-06-23 United States Surgical Corporation Absorbable coating composition, coated sutures and method of preparation
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
JPH0474025B2 (en) * 1988-03-04 1992-11-25
JP2561309B2 (en) * 1988-03-28 1996-12-04 テルモ株式会社 Medical material and a method of manufacturing the same
US5843156A (en) * 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US5470829A (en) * 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
DE68929425T2 (en) * 1988-12-29 2003-06-05 Genzyme Corp Absorbable blend for controlled release
US5514550A (en) * 1989-02-03 1996-05-07 Johnson & Johnson Clinical Diagnostics, Inc. Nucleic acid test article and its use to detect a predetermined nucleic acid
US5008334A (en) * 1989-02-28 1991-04-16 Basf Corporation Resins of epoxy/aromatic diol copolymer and block copolymer of epoxy/aromatic diol copolymer and a epoxy-capped polybutadiene (co)polymer
US5698531A (en) * 1989-03-31 1997-12-16 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5292522A (en) * 1989-06-20 1994-03-08 Rohm Gmbh Aqueous film coating agent for solid medicaments
FR2649321A1 (en) * 1989-07-07 1991-01-11 Inst Nat Sante Rech Med Compositions based on nucleotide derivatives, methods for preparing them and their uses, in particular as pharmaceutical compositions
US5723119A (en) * 1989-07-28 1998-03-03 Schering Corporation Method for enhancing wound healing/repair with IL-4
IL95952D0 (en) * 1989-10-19 1991-07-18 Sterling Drug Inc Aerosol composition for topical medicament
US5271961A (en) * 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
EP0550436A1 (en) * 1989-11-06 1993-07-14 Alkermes Controlled Therapeutics, Inc. Protein microspheres and methods of using them
WO1991006286A1 (en) * 1989-11-06 1991-05-16 Enzytech, Inc. Method for producing protein microspheres
US5258436A (en) * 1989-12-19 1993-11-02 Fmc Corporation Film-forming composition; method of producing same and use for coating pharmaceuticals and foods and the like
US5147383A (en) * 1990-02-01 1992-09-15 Ethicon, Inc. Suture coated with a polyvinyl ester
CA2316159C (en) * 1990-02-13 2008-04-29 Takeda Chemical Industries, Ltd. Prolonged release microcapsules
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
WO1991015260A1 (en) * 1990-03-30 1991-10-17 Alza Corporation Device and method for iontophoretic drug delivery
FR2660556B1 (en) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Microspheres, their process for the preparation and use.
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
US5460831A (en) * 1990-06-22 1995-10-24 The Regents Of The University Of California Targeted transfection nanoparticles
US5100433A (en) * 1990-11-08 1992-03-31 Ethicon, Inc. Suture coated with a copolymer coating composition
US5102420A (en) * 1990-11-14 1992-04-07 Ethicon, Inc. Suture coated with a polyetheramide
US5674192A (en) * 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5304121A (en) * 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5102402A (en) * 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters
NZ286242A (en) * 1991-03-26 1997-11-24 Csl Ltd Use of veterinary implant as a single dose vaccination system: rupturable polymer film coating around core of active agent and water soluble excipient
CA2084194C (en) * 1991-04-02 2003-05-20 Gregory John Russell-Jones Oral delivery systems for microparticles
DE4120760A1 (en) * 1991-06-24 1993-03-04 3 M Medica Gmbh Carrier systems for drug
CA2082411A1 (en) * 1991-06-28 1992-12-29 Robert D. Rosenberg Localized oligonucleotide therapy
ES2034891B1 (en) * 1991-08-08 1993-12-16 Cusi Lab Continuous production process of dispersed colloidal systems in the form of nanocapsules or nanoparticles.
WO1993007924A1 (en) * 1991-10-18 1993-04-29 Spire Corporation Bactericidal coatings for implants
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
DE69328523T2 (en) * 1992-02-13 2000-09-21 Surmodics Inc Immobilization of a chemical species in a networked matrix
US5225485A (en) * 1992-03-03 1993-07-06 United States Surgical Corporation Polyetherimide ester suture and its method of manufacture and method of use
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces
FI91713C (en) * 1992-04-23 1994-08-10 Axidental Oy New bioactive coverings and their preparation and use
US6197346B1 (en) * 1992-04-24 2001-03-06 Brown Universtiy Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
US5312437A (en) * 1992-06-12 1994-05-17 United States Surgical Corporation Absorbable coating composition and suture coated therewith
AU6014094A (en) * 1992-12-02 1994-06-22 Baylor College Of Medicine Episomal vectors for gene therapy
TW333456B (en) * 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
AT167396T (en) * 1993-02-22 1998-07-15 Alza Corp Compositions for oral delivery of drugs
JPH08511418A (en) * 1993-04-19 1996-12-03 メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ Treatment with a long-acting by sustained release delivery of antisense oligodeoxyribonucleotides of biodegradable microparticulates
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
EP0797988B1 (en) * 1993-07-19 2009-01-14 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions and methods of use
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
DE69529054D1 (en) * 1994-02-28 2003-01-16 Nanopharm Ag System for targeted drug supply, process for its production and use
AU710504B2 (en) * 1994-03-15 1999-09-23 Brown University Research Foundation Polymeric gene delivery system
US5480963A (en) * 1994-07-22 1996-01-02 United States Surgical Corporation Absorbable copolymers derived from tricarboxylic acids and surgical articles made therefrom
US5652225A (en) * 1994-10-04 1997-07-29 St. Elizabeth's Medical Center Of Boston, Inc. Methods and products for nucleic acid delivery
AU700903B2 (en) * 1994-10-12 1999-01-14 Focal, Inc. Targeted delivery via biodegradable polymers
US5545135A (en) * 1994-10-31 1996-08-13 Boston Scientific Corporation Perfusion balloon stent
US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6395029B1 (en) * 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents

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EP0910301A1 (en) 1999-04-28
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CA2257976C (en) 2008-01-15
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WO1997047254A1 (en) 1997-12-18
US6143037A (en) 2000-11-07

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