IL122818D0 - Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof - Google Patents

Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof

Info

Publication number
IL122818D0
IL122818D0 IL12281897A IL12281897A IL122818D0 IL 122818 D0 IL122818 D0 IL 122818D0 IL 12281897 A IL12281897 A IL 12281897A IL 12281897 A IL12281897 A IL 12281897A IL 122818 D0 IL122818 D0 IL 122818D0
Authority
IL
Israel
Prior art keywords
uses
soluble receptor
ligand protein
protein analogs
chimeric interleukin
Prior art date
Application number
IL12281897A
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to IL12128497A priority Critical patent/IL121284D0/en
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL12281897A priority patent/IL122818D0/en
Priority claimed from IL13397298A external-priority patent/IL133972D0/en
Priority claimed from SI9830861T external-priority patent/SI0991661T1/en
Publication of IL122818D0 publication Critical patent/IL122818D0/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26323470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL122818(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

IL12281897A 1997-07-10 1997-12-30 Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof IL122818D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL12128497A IL121284D0 (en) 1997-07-10 1997-07-10 Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
IL12281897A IL122818D0 (en) 1997-07-10 1997-12-30 Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof

Applications Claiming Priority (30)

Application Number Priority Date Filing Date Title
IL12281897A IL122818D0 (en) 1997-07-10 1997-12-30 Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
EP98931006A EP0991661B1 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
SK6-2000A SK287039B6 (en) 1997-07-10 1998-07-09 Chimeric glycosylized protein - sIL-6R/IL-6 and analogs thereof, a DNA sequence, transformed mammal cells containing DNA vector, process for producing a chimeric protein, a pharmaceutical composition comprising thereof and use thereof
NZ50213998A NZ502139A (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/interleukin-6 fusion protein (sIL-6R/IL-6) to treat malignant melanoma cells
EA200000109A EA004793B1 (en) 1997-07-10 1998-07-09 The chimeric protein of the soluble interleukin-6 receptor / ligand analogs and methods of using
DE1998636217 DE69836217T2 (en) 1997-07-10 1998-07-09 Chimeric soluble interleukin-6 receptor / ligand protein, analog and uses
BR9812096A BR9812096B1 (en) 1997-07-10 1998-07-09 protein interleukin-6 (IL-6), interleukin-6 receptor (sIL-6R) soluble chimeric glycosylated (sIL-6R / IL-6) and biologically active analogs, its process for preparation and use, and DNA sequence DNA vector and a pharmaceutical composition.
PCT/IL1998/000321 WO1999002552A2 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
JP2000502071A JP4402288B2 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor / ligand protein, analogs thereof and their use
PL338002A PL199212B1 (en) 1997-07-10 1998-07-09 Chimeric protein of interleukin 6-dissolvable receptor/ligands, its analoques and applications thereof
CA 2295936 CA2295936C (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
PT98931006T PT991661E (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
CZ20000075A CZ302488B6 (en) 1997-07-10 1998-07-09 Chimeric glycosylated soluble protein (sIL-6R/IL-6)
AT98931006T AT342915T (en) 1997-07-10 1998-07-09 Chimeric soluble interleukin-6 receptor / ligand protein, analog and uses
HU0002426A HU225855B1 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
US09/462,416 US7198781B1 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand proteins
IL13397298A IL133972D0 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
AU81271/98A AU758161B2 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
KR10-2000-7000080A KR100505172B1 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
CN 98808941 CN1185348C (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein and application thereof
DK98931006T DK0991661T3 (en) 1997-07-10 1998-07-09 Chimeric Interleukin-6 receptor solution / ligand protein, analogs thereof and uses thereof
EEP200000012A EE05519B1 (en) 1997-07-10 1998-07-09 im '' kos RNE gl lated soluble interleukin 6retseptori / IL-6 protein and biologically active analogs thereof used in the method of DNA j "transformed mammalian cell and the DNA vector rjestus pharmaceutical komposits
SI9830861T SI0991661T1 (en) 1997-07-10 1998-07-09 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
ES98931006T ES2271999T3 (en) 1997-07-10 1998-07-09 Chimeric Protein soluble interleukin-6 receptor / ligand analogs and their uses.
ARP980103377 AR013201A1 (en) 1997-07-10 1998-07-10 Protein interleukin-6 receptor interleukin-6 soluble chimeric, analogs thereof, a DNA sequence, a DNA vector, cells unable transformed mammal to generate an animal, a method for producing a chimeric protein, the use of said protein for preparing or
NO20000086A NO327397B1 (en) 1997-07-10 2000-01-07 Chimeric sIL-6R / IL-6 protein, DNA, vector, cell, process feed for the preparation and various uses of said protein
IL133972A IL133972A (en) 1997-07-10 2000-01-10 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
BG104070A BG64680B1 (en) 1997-07-10 2000-01-10 Chimeric protein of interleukin-6, soluble receptor/ligand, its analogues and their application
HK01102418A HK1031895A1 (en) 1997-07-10 2001-04-04 Chimeric interleukin-6 soluble receptor/ligand protein and uses thereof.
US11/688,640 US7374912B2 (en) 1997-07-10 2007-03-20 Nucleic acids encoding chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof

Publications (1)

Publication Number Publication Date
IL122818D0 true IL122818D0 (en) 1998-08-16

Family

ID=26323470

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12281897A IL122818D0 (en) 1997-07-10 1997-12-30 Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
IL133972A IL133972A (en) 1997-07-10 2000-01-10 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL133972A IL133972A (en) 1997-07-10 2000-01-10 Chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof

Country Status (26)

Country Link
US (2) US7198781B1 (en)
EP (1) EP0991661B1 (en)
JP (1) JP4402288B2 (en)
KR (1) KR100505172B1 (en)
CN (1) CN1185348C (en)
AR (1) AR013201A1 (en)
AT (1) AT342915T (en)
AU (1) AU758161B2 (en)
BG (1) BG64680B1 (en)
BR (1) BR9812096B1 (en)
CA (1) CA2295936C (en)
CZ (1) CZ302488B6 (en)
DE (1) DE69836217T2 (en)
DK (1) DK0991661T3 (en)
EA (1) EA004793B1 (en)
EE (1) EE05519B1 (en)
ES (1) ES2271999T3 (en)
HK (1) HK1031895A1 (en)
HU (1) HU225855B1 (en)
IL (2) IL122818D0 (en)
NO (1) NO327397B1 (en)
NZ (1) NZ502139A (en)
PL (1) PL199212B1 (en)
PT (1) PT991661E (en)
SK (1) SK287039B6 (en)
WO (1) WO1999002552A2 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818D0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
US5919763A (en) * 1998-06-01 1999-07-06 Hadasit Medical Research Services And Development Company Ltd. IL-6/SIL-6R complex for promotion of liver functions
US20040170604A1 (en) 1998-07-06 2004-09-02 Tosoh Corporation IL-6 receptor IL-6 direct fusion protein
EP1094081B1 (en) * 1998-07-06 2005-09-21 Tosoh Corporation Fused protein with direct bond of il-6-receptor to il-6
EP1165791B1 (en) 1999-03-09 2007-10-31 ZymoGenetics, Inc. Human cytokine as ligand of the zalpha receptor and uses thereof
IL130586D0 (en) * 1999-06-21 2000-06-01 Yeda Res & Dev IL6RIL6 chimera for the treatment of demyelinating diseases
CA2447632C (en) * 2000-06-16 2011-08-02 Asterion Limited Fusion protein agonist comprising a growth hormone binding portion and an external domain of a growth hormone receptor
AU2001291849B2 (en) 2000-09-14 2005-11-24 Ares Trading S.A. Use of IL-6R/IL-6 chimera in huntington's disease
DE10106827A1 (en) * 2001-02-14 2002-09-05 Stefan Rose-John Use of a conjugate of interleukin-6 (IL-6) and its receptor in the induction of cellular expression of the stem cell factor (SCF) and Flat-3 ligand (Flt-3L)
DE10107737A1 (en) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Use of a conjugate of IL-6 and an IL-6 receptor for tumor therapy
KR100453877B1 (en) 2001-07-26 2004-10-20 메덱스젠 주식회사 METHOD OF MANUFACTURING Ig-FUSION PROTEINS BY CONCATAMERIZATION, TNFR/Fc FUSION PROTEINS MANUFACTURED BY THE METHOD, DNA CODING THE PROTEINS, VECTORS INCLUDING THE DNA, AND CELLS TRANSFORMED BY THE VECTOR
GB0119015D0 (en) * 2001-08-03 2001-09-26 Univ Cardiff A fusion protein
GB2384001B (en) * 2001-12-14 2004-02-04 Asterion Ltd Chimeric growth hormone-growth hormone receptor proteins
IL147412D0 (en) * 2001-12-31 2002-08-14 Yeda Res & Dev The use of il6r/il6 chimera in nerve cell regeneration
EP1499332A4 (en) * 2002-04-29 2006-12-06 Hadasit Med Res Service Compositions and methods for treating cancer with an oncolytic viral agent
WO2004069173A2 (en) 2003-01-31 2004-08-19 The Trustees Of The University Of Pennsylvania Methods for modulating an inflammatory response
FR2850621B1 (en) 2003-02-04 2006-12-08 Journee Paul Connector connecting a wiper arm to a wiper blade, which has two tabs to the transverse locking wiper arm
DE10321317A1 (en) * 2003-05-13 2004-12-23 Christian-Albrechts-Universität Zu Kiel Detecting complexes of interleukin-6 with its soluble receptor, useful e.g. in screening for agents that antagonize interaction between the complex and soluble gp130-Fc, using antibody specific for the receptor component
IL157309D0 (en) * 2003-08-07 2004-02-19 Applied Research Systems Method for the purification of a non-immunoglobulin protein
IL159558D0 (en) * 2003-12-24 2004-06-01 Applied Research Systems Use of il-6 in liver injury
IL161672D0 (en) 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
IL161673D0 (en) 2004-04-29 2004-09-27 Applied Research Systems Compositions and methods for therapy of chemotherapy-induced neuropathy
AU2012261726B2 (en) * 2005-08-29 2015-03-12 Technion Research & Development Foundation Ltd. Media for Culturing Stem Cells
AU2006286149B2 (en) 2005-08-29 2012-09-13 Technion Research And Development Foundation Ltd. Media for culturing stem cells
EP1777294A1 (en) * 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
JP2009543579A (en) 2006-07-19 2009-12-10 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア As a target for anti-inflammatory response WSX-1 / p28
EP2059586B1 (en) * 2006-08-02 2016-07-20 Technion Research & Development Foundation Ltd. Methods of expanding embryonic stem cells in a suspension culture
US8052968B2 (en) 2006-10-16 2011-11-08 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
WO2008156655A2 (en) * 2007-06-15 2008-12-24 Genelux Corporation Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors
GB0715216D0 (en) * 2007-08-03 2007-09-12 Asterion Ltd Leptin
JP2010535487A (en) * 2007-08-03 2010-11-25 アステリオン・リミテッド Granulocyte colony stimulating factor
MX2011000071A (en) * 2008-07-02 2011-05-03 Emergent Product Dev Seattle Il6 immunotherapeutics.
JP2011526794A (en) * 2008-07-02 2011-10-20 エマージェント プロダクト デベロップメント シアトル, エルエルシー TGF-beta antagonists multiple target binding molecule
AU2010205782A1 (en) 2009-01-16 2011-09-08 Agirx Limited Vaccine compositions
WO2011079308A2 (en) 2009-12-23 2011-06-30 Emergent Product Development Seattle, Llc Compositions comprising tnf-alpha and il-6 antagonists and methods of use thereof
US10214722B2 (en) 2010-09-07 2019-02-26 Technion Research & Development Foundation Limited Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture
EP2832856A4 (en) 2012-03-29 2016-01-27 Chugai Pharmaceutical Co Ltd Anti-lamp5 antibody and utilization thereof
US20160194369A1 (en) * 2013-08-12 2016-07-07 Merck Sharp & Dohme Corp. Methods and compositions for co-expression of polypeptides of inerest and il6
CN104826093A (en) * 2015-04-16 2015-08-12 刘永庆 Th2 immune response antagonist for treating chronic infectious hepatopathy, and yolk antibody thereof
CN104922659B (en) * 2015-07-03 2018-04-20 刘永庆 Prevention and treatment of tumors and / or chronic tuberculosis Th2 immune response Inhibitors and Their Application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it
IL99803A (en) 1991-10-20 1997-02-18 Yeda Res & Dev Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas
PL190445B1 (en) 1995-05-15 2005-12-30 Akademia Medyczna im. K.Marcinkowskiego Genetic vaccine against carcinoma
DE19608813C2 (en) 1996-03-07 1998-07-02 Angewandte Gentechnologie Syst Conjugate to influence interactions between proteins
IL122818D0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
WO1999032141A1 (en) * 1997-12-19 1999-07-01 Applied Research Systems Ars Holding N.V. Ifnar2/ifn complex

Also Published As

Publication number Publication date
JP2001509371A (en) 2001-07-24
HU0002426A2 (en) 2000-11-28
SK62000A3 (en) 2000-07-11
BR9812096A (en) 2000-07-18
DK0991661T3 (en) 2007-02-05
BR9812096B1 (en) 2011-09-06
HU0002426A3 (en) 2003-01-28
BG64680B1 (en) 2005-11-30
CN1185348C (en) 2005-01-19
NO327397B1 (en) 2009-06-22
AT342915T (en) 2006-11-15
JP4402288B2 (en) 2010-01-20
SK287039B6 (en) 2009-10-07
EA004793B1 (en) 2004-08-26
BG104070A (en) 2000-11-30
PL338002A1 (en) 2000-09-25
AU8127198A (en) 1999-02-08
EE05519B1 (en) 2012-02-15
CA2295936A1 (en) 1999-01-21
IL133972A (en) 2015-07-30
KR20010021522A (en) 2001-03-15
HK1031895A1 (en) 2005-09-09
HU225855B1 (en) 2007-11-28
PL199212B1 (en) 2008-08-29
WO1999002552A3 (en) 1999-04-01
CA2295936C (en) 2009-05-26
EP0991661A2 (en) 2000-04-12
NZ502139A (en) 2002-03-28
DE69836217T2 (en) 2007-08-23
ES2271999T3 (en) 2007-04-16
WO1999002552A2 (en) 1999-01-21
US7374912B2 (en) 2008-05-20
CN1269835A (en) 2000-10-11
US20070172455A1 (en) 2007-07-26
CZ200075A3 (en) 2000-08-16
EE200000012A (en) 2000-08-15
CZ302488B6 (en) 2011-06-15
AR013201A1 (en) 2000-12-13
NO20000086L (en) 2000-03-08
AU758161B2 (en) 2003-03-20
KR100505172B1 (en) 2005-08-03
PT991661E (en) 2007-01-31
DE69836217D1 (en) 2006-11-30
NO20000086D0 (en) 2000-01-07
EA200000109A1 (en) 2000-08-28
US7198781B1 (en) 2007-04-03
EP0991661B1 (en) 2006-10-18

Similar Documents

Publication Publication Date Title
DE69807872D1 (en) Thermoplastisches polyetherurethan
DE69709184D1 (en) Knöchel-fuss orthese
DE69808438D1 (en) Hüftprothese
GB2322627B (en) Novel phosphino derivatives
DE69809754D1 (en) Substituierte 6-phenylphenanthridine
DE69835201D1 (en) Neoglycoproteine
EG23685A (en) Activated protein c formulations
ZA9802714B (en) Catalytic composition
GB9820718D0 (en) Clip
IL125073D0 (en) Wsx receptor and ligands
PT929578E (en) Human antibodies connecting human tnfalfa
EP1113799A4 (en) Protein formulations
TW331894U (en) Clip
DE69820902D1 (en) Snowboardkörper
GB9707414D0 (en) Anatomical probe
PL192957B1 (en) Chimeric flaviviral vaccines
HU9603525D0 (en) Vironectin receptor antagonists
IL154066A (en) Sensor connection means
IL131867D0 (en) Anti-epileptogenic agents
ZA9610738B (en) Subtype selective nmda receptor ligands and the use thereof
IL133233A (en) Position determination
IL136326D0 (en) Human interferon-epsilon: a type i interferon
IL140137A (en) Receptor bodies specifically binding tie-2 ligands
CZ114198A3 (en) Secured port interface
EP0984778A4 (en) Neuropeptide-y ligands