IL107292D0 - Substituted benzylaminoquinuclidines - Google Patents

Substituted benzylaminoquinuclidines


Publication number
IL107292D0 IL10729293A IL10729293A IL107292D0 IL 107292 D0 IL107292 D0 IL 107292D0 IL 10729293 A IL10729293 A IL 10729293A IL 10729293 A IL10729293 A IL 10729293A IL 107292 D0 IL107292 D0 IL 107292D0
Prior art keywords
Prior art date
Application number
Original Assignee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to JP28313592A priority Critical patent/JP2656699B2/en
Application filed by Pfizer filed Critical Pfizer
Publication of IL107292D0 publication Critical patent/IL107292D0/en


IL10729293A 1992-10-21 1993-10-14 Substituted benzylaminoquinuclidines IL107292D0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP28313592A JP2656699B2 (en) 1992-10-21 1992-10-21 Substituted benzyl aminoquinuclidine

Publications (1)

Publication Number Publication Date
IL107292D0 true IL107292D0 (en) 1994-01-25



Family Applications (1)

Application Number Title Priority Date Filing Date
IL10729293A IL107292D0 (en) 1992-10-21 1993-10-14 Substituted benzylaminoquinuclidines

Country Status (16)

Country Link
EP (1) EP0665844B1 (en)
JP (1) JP2656699B2 (en)
AT (1) AT196140T (en)
AU (1) AU5165393A (en)
CA (1) CA2146259C (en)
DE (2) DE69329386T2 (en)
DK (1) DK0665844T3 (en)
ES (1) ES2149215T3 (en)
FI (1) FI114636B (en)
GR (1) GR3034498T3 (en)
HU (1) HUT65133A (en)
IL (1) IL107292D0 (en)
MX (1) MX9306527A (en)
PT (1) PT665844E (en)
WO (1) WO1994008997A1 (en)
ZA (1) ZA9307780B (en)

Families Citing this family (37)

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Publication number Priority date Publication date Assignee Title
WO1996014845A1 (en) * 1994-11-10 1996-05-23 Pfizer Inc. Nk-1 receptor antagonists for the treatment of eye disorders
FR2728166B1 (en) 1994-12-19 1997-02-07
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (en) 1995-11-20 1999-03-05 Oreal Use of a TNF-alpha antagonist for the treatment of skin redness of neurogenic origin
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
CN103880827B (en) 2004-07-15 2017-01-04 阿尔巴尼分子研究公司 The application of the reuptake of aryl and the substituted tetrahydroisoquinoline of heteroaryl and blocking-up norepinephrine, dopamine and serotonin
WO2006123182A2 (en) 2005-05-17 2006-11-23 Merck Sharp & Dohme Limited Cyclohexyl sulphones for treatment of cancer
JP5258561B2 (en) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ, インコーポレイテッド Aryl and heteroaryl substituted tetrahydrobenzazepines and their use to block reuptake of norepinephrine, dopamine and serotonin
EP1940842B1 (en) 2005-09-29 2012-05-30 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
CA2770486C (en) 2006-09-22 2014-07-15 Merck Sharp & Dohme Corp. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
EP3536690A1 (en) 2007-01-10 2019-09-11 MSD Italia S.r.l. Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP2145884B1 (en) 2007-04-02 2014-08-06 Msd K.K. Indoledione derivative
EP3103791B1 (en) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
WO2009111354A2 (en) 2008-03-03 2009-09-11 Tiger Pharmatech Tyrosine kinase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010000073A1 (en) 2008-07-03 2010-01-07 Neuraxon, Inc. Benzoxazines, benzothiazines, and related compounds having nos inhibitory activity
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
AU2010247735B2 (en) 2009-05-12 2015-07-16 Albany Molecular Research, Inc. Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
AU2010247849B2 (en) 2009-05-12 2015-11-19 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
ES2662072T3 (en) 2009-05-12 2018-04-05 Albany Molecular Research, Inc. 7 - ([1,2,4] triazolo [1,5-a] pyridin-6-yl) -4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydroisoquinoline and use thereof
EP2488028A4 (en) 2009-10-14 2013-05-01 Merck Sharp & Dohme SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
WO2011163330A1 (en) 2010-06-24 2011-12-29 Merck Sharp & Dohme Corp. Novel heterocyclic compounds as erk inhibitors
EP3330377A1 (en) 2010-08-02 2018-06-06 Sirna Therapeutics, Inc. Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
US8883801B2 (en) 2010-08-23 2014-11-11 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
EP2613782B1 (en) 2010-09-01 2016-11-02 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
EP2615916B1 (en) 2010-09-16 2017-01-04 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel erk inhibitors
ES2663009T3 (en) 2010-10-29 2018-04-10 Sirna Therapeutics, Inc. Inhibition of RNA-mediated gene expression using short interference nucleic acids (ANic)
EP2654748B1 (en) 2010-12-21 2016-07-27 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
WO2012143879A1 (en) 2011-04-21 2012-10-26 Piramal Healthcare Limited A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
US9023865B2 (en) 2011-10-27 2015-05-05 Merck Sharp & Dohme Corp. Compounds that are ERK inhibitors
EP2844261B1 (en) 2012-05-02 2018-10-17 Sirna Therapeutics, Inc. SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
CN105050598B (en) 2012-09-28 2018-04-27 默沙东公司 New compound as ERK inhibitor
BR112015012295A2 (en) 2012-11-28 2017-07-11 Merck Sharp & Dohme methods for treating a patient, and kit for identifying a cancer patient
JP6387013B2 (en) 2012-12-20 2018-09-12 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Substituted imidazopyridines as HDM2 inhibitors
EP2951180B1 (en) 2013-01-30 2018-05-02 Merck Sharp & Dohme Corp. 2,6,7,8 substituted purines as hdm2 inhibitors
EP3041938A1 (en) 2013-09-03 2016-07-13 Moderna Therapeutics, Inc. Circular polynucleotides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX18467A (en) * 1988-11-23 1993-07-01 Pfizer Therapeutic agents quinuclidines
EP0585328B1 (en) * 1991-05-22 2002-01-09 Pfizer Inc. Substituted 3-aminoquinuclidines

Also Published As

Publication number Publication date
HU9302965D0 (en) 1993-12-28
DE69329386D1 (en) 2000-10-12
DK665844T3 (en)
CA2146259C (en) 1998-04-07
PT665844E (en) 2001-01-31
WO1994008997A1 (en) 1994-04-28
EP0665844B1 (en) 2000-09-06
MX9306527A (en) 1994-07-29
AT196140T (en) 2000-09-15
DE69329386T2 (en) 2001-01-04
HUT65133A (en) 1994-04-28
GR3034498T3 (en) 2000-12-29
JP2656699B2 (en) 1997-09-24
AU5165393A (en) 1994-05-09
ZA9307780B (en) 1995-04-20
FI934626D0 (en)
FI934626A0 (en) 1993-10-20
JPH06135963A (en) 1994-05-17
EP0665844A1 (en) 1995-08-09
FI114636B (en) 2004-11-30
DK0665844T3 (en) 2000-10-16
FI114636B1 (en)
CA2146259A1 (en) 1994-04-28
ES2149215T3 (en) 2000-11-01
FI934626A (en) 1994-04-22

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