IL106695D0 - Diketopiperazine derivatives,their preparation and use - Google Patents

Diketopiperazine derivatives,their preparation and use

Info

Publication number
IL106695D0
IL106695D0 IL10669593A IL10669593A IL106695D0 IL 106695 D0 IL106695 D0 IL 106695D0 IL 10669593 A IL10669593 A IL 10669593A IL 10669593 A IL10669593 A IL 10669593A IL 106695 D0 IL106695 D0 IL 106695D0
Authority
IL
Israel
Prior art keywords
preparation
use
diketopiperazine derivatives
diketopiperazine
derivatives
Prior art date
Application number
IL10669593A
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB929217331A priority Critical patent/GB9217331D0/en
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of IL106695D0 publication Critical patent/IL106695D0/en

Links

IL10669593A 1992-08-14 1993-08-15 Diketopiperazine derivatives,their preparation and use IL106695D0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB929217331A GB9217331D0 (en) 1992-08-14 1992-08-14 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
IL106695D0 true IL106695D0 (en) 1993-12-08

Family

ID=10720385

Family Applications (2)

Application Number Title Priority Date Filing Date
IL10669693A IL106696D0 (en) 1992-08-14 1993-08-15 Diketopiperazines,their preparation and use
IL10669593A IL106695D0 (en) 1992-08-14 1993-08-15 Diketopiperazine derivatives,their preparation and use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL10669693A IL106696D0 (en) 1992-08-14 1993-08-15 Diketopiperazines,their preparation and use

Country Status (24)

Country Link
US (1) US5700804A (en)
EP (2) EP0672036A1 (en)
JP (2) JPH08504176A (en)
KR (2) KR950702968A (en)
AT (1) AT162186T (en)
AU (2) AU678172B2 (en)
BG (2) BG99496A (en)
BR (2) BR9306904A (en)
CA (2) CA2141938A1 (en)
CZ (2) CZ38195A3 (en)
DE (2) DE69316370D1 (en)
DK (1) DK0655060T3 (en)
ES (1) ES2111169T3 (en)
FI (2) FI950616A (en)
GB (2) GB9217331D0 (en)
GR (1) GR3026272T3 (en)
HU (2) HUT71592A (en)
IL (2) IL106696D0 (en)
PL (2) PL307437A1 (en)
RU (2) RU95108387A (en)
SK (2) SK19495A3 (en)
TW (1) TW334427B (en)
WO (2) WO1994004512A1 (en)
ZA (2) ZA9305969B (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
DK85193D0 (en) 1993-07-16 1993-07-16 Cancerforskningsfondet Af 1989 Suppression of inhibitors
IL112627D0 (en) * 1994-02-14 1995-05-26 Xenova Ltd Diketopiperazines, their preparation and pharmaceutical or veterinary compositions containing them
GB9402809D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9402805D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
US5891877A (en) * 1995-02-14 1999-04-06 Xenova Limited Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds
GB9426071D0 (en) * 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
GB2310854B (en) * 1994-12-23 1998-09-09 Xenova Ltd Piperazine-2,5-dione derivatives as modulators of multi-drug resistance
GB9426090D0 (en) * 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
GB9426224D0 (en) * 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
GB2311781B (en) * 1994-12-23 1998-09-16 Xenova Ltd Piperazine 2,5 dione derivatives as modulators of multi-drug resistance
JP2003515590A (en) * 1999-12-03 2003-05-07 エモリー ユニバーシティ Curcumin analog for the treatment of cancer
AT417614T (en) * 2000-05-09 2009-01-15 Angiorx Corp Piperazine CONNECTIONS
US7288545B2 (en) * 2000-05-09 2007-10-30 Angiorx Corporation Piperazinedione compounds
ES2381775T3 (en) 2000-08-04 2012-05-31 Dmi Biosciences, Inc. Procedure of the use of diketopiperazines and their composition
EP1315777B1 (en) 2000-09-06 2007-10-31 AP Pharma, Inc. Degradable polyacetal polymers
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
WO2002062797A2 (en) 2000-12-29 2002-08-15 Celltech R & D, Inc. Pharmaceutical uses and synthesis of diketopiperazines
GB2372740A (en) * 2001-01-17 2002-09-04 Xenova Ltd Diketopiperazines
CA2478522A1 (en) * 2002-03-08 2003-09-18 Emory University Novel curcuminoid-factor viia constructs as suppressors of tumor growth and angiogenesis
US7919497B2 (en) 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
AT374767T (en) 2002-08-02 2007-10-15 Nereus Pharmaceuticals Inc Dehydrophenylahistines and analogs thereof and a process for the production of dehydrophenylahistines and analogue thereof
US7935704B2 (en) 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
DE10238144A1 (en) * 2002-08-15 2004-02-26 Basf Ag Use of aryl-substituted 3,6-dialkylidene-2,5-piperazinedione derivatives as photostable UV filters in cosmetic or pharmaceutical compositions for protecting human skin or hair against solar radiation
DK1571970T3 (en) * 2002-10-02 2011-11-28 Dmi Biosciences Inc Diagnosis and monitoring of diseases
KR20150080004A (en) 2003-05-15 2015-07-08 앰피오 파마슈티컬스 인코퍼레이티드 Treatment of t-cell mediated diseases
GB0314738D0 (en) 2003-06-24 2003-07-30 Glaxo Group Ltd Novel compounds
WO2006105051A2 (en) * 2005-03-29 2006-10-05 Nereus Pharmaceuticals, Inc. Synthesis of diketopiperazines
WO2007098504A1 (en) * 2006-02-24 2007-08-30 Emory University Prodrugs of curcumin analogs
US8129527B2 (en) 2006-11-03 2012-03-06 Nereus Pharmacuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
JP5856843B2 (en) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ,インコーポレイテッド Pharmaceutical composition using diketopiperazine
EP2613786A4 (en) 2010-09-07 2013-10-23 Dmi Acquisition Corp Treatment of diseases
AU2012214592B2 (en) * 2011-02-10 2017-03-09 Mannkind, Corp Formation of N-protected bis-3,6-(4-aminoalkyl) -2,5,diketopiperazine
NZ623871A (en) 2011-10-10 2016-02-26 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
CA2846598C (en) 2011-10-10 2019-12-10 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
CN103396372B (en) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 2,5-diketopiperazine derivative, as well as preparation method and application thereof in preparing control agent for resisting marine fouling organisms
CN105272968B (en) * 2014-06-10 2018-03-13 首都医科大学 The diketone of (3S, 6R) 3,6 disubstituted piperazine 2,5, it is prepared and application
WO2016028790A1 (en) 2014-08-18 2016-02-25 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
CN104610170B (en) * 2015-01-14 2017-02-01 中国科学院南海海洋研究所 2, 5-diketopiperazine derivative as well as preparation method and application thereof
AU2016229294A1 (en) 2015-03-06 2017-09-28 Beyondspring Pharmaceuticals, Inc. Method of treating cancer associated with a RAS mutation
MX2017011375A (en) 2015-03-06 2018-01-23 Beyondspring Pharmaceuticals Inc Method of treating a brain tumor.
CN108026075A (en) 2015-07-13 2018-05-11 万春药业公司 Pune's cloth woods composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE621862C (en) * 1932-07-01 1935-11-14 Guenther Schiemann Dr A process for the preparation of ring-fluorinated condensation products arylaldehydes
BE584914A (en) * 1958-11-24
JPS648031B2 (en) * 1980-09-04 1989-02-10 Ricoh Kk
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
SK19495A3 (en) 1995-11-08
GR3026272T3 (en) 1998-06-30
FI950617D0 (en)
DE69316370T2 (en) 1998-07-16
EP0655060A1 (en) 1995-05-31
TW334427B (en) 1998-06-21
BR9306904A (en) 1998-12-08
EP0672036A1 (en) 1995-09-20
PL307437A1 (en) 1995-05-29
KR950702968A (en) 1995-08-23
FI950617A (en) 1995-04-13
DE69316370D1 (en) 1998-02-19
JPH08504176A (en) 1996-05-07
ZA9305968B (en) 1995-02-16
PL307438A1 (en) 1995-05-29
RU95108387A (en) 1996-12-10
GB9502859D0 (en) 1995-04-05
RU95108759A (en) 1996-12-10
EP0655060B1 (en) 1998-01-14
ZA9305969B (en) 1995-02-16
JPH08504175A (en) 1996-05-07
WO1994004512A1 (en) 1994-03-03
CA2141938A1 (en) 1994-03-03
FI950616A (en) 1995-04-13
KR950702967A (en) 1995-08-23
AU693420B2 (en) 1998-07-02
DK0655060T3 (en) 1998-02-09
HU9500437D0 (en) 1995-04-28
GB2284420B (en) 1996-09-25
CZ38195A3 (en) 1995-09-13
FI950616A0 (en) 1995-02-13
AT162186T (en) 1998-01-15
DK655060T3 (en)
GB9217331D0 (en) 1992-09-30
HUT71593A (en) 1996-01-29
CA2141939A1 (en) 1994-03-03
GB2284420A (en) 1995-06-07
BG99495A (en) 1995-12-29
HUT71592A (en) 1996-01-29
FI950616D0 (en)
AU4726593A (en) 1994-03-15
BR9306905A (en) 1998-12-08
US5700804A (en) 1997-12-23
SK19595A3 (en) 1995-09-13
WO1994004513A1 (en) 1994-03-03
HU9500436D0 (en) 1995-04-28
AU4726493A (en) 1994-03-15
CZ38395A3 (en) 1995-10-18
FI950617A0 (en) 1995-02-13
AU678172B2 (en) 1997-05-22
BG99496A (en) 1995-12-29
ES2111169T3 (en) 1998-03-01
IL106696D0 (en) 1993-12-08

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