IL103817A0 - Method and intermediates for the preparation of prolineboronic acid esters - Google Patents

Method and intermediates for the preparation of prolineboronic acid esters

Info

Publication number
IL103817A0
IL103817A0 IL103817A IL10381792A IL103817A0 IL 103817 A0 IL103817 A0 IL 103817A0 IL 103817 A IL103817 A IL 103817A IL 10381792 A IL10381792 A IL 10381792A IL 103817 A0 IL103817 A0 IL 103817A0
Authority
IL
Israel
Prior art keywords
intermediates
preparation
acid esters
prolineboronic acid
prolineboronic
Prior art date
Application number
IL103817A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL103817A0 publication Critical patent/IL103817A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL103817A 1991-11-22 1992-11-20 Method and intermediates for the preparation of prolineboronic acid esters IL103817A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79614891A 1991-11-22 1991-11-22
US93619892A 1992-08-26 1992-08-26

Publications (1)

Publication Number Publication Date
IL103817A0 true IL103817A0 (en) 1993-04-04

Family

ID=27121696

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103817A IL103817A0 (en) 1991-11-22 1992-11-20 Method and intermediates for the preparation of prolineboronic acid esters

Country Status (17)

Country Link
EP (1) EP0641347A1 (enrdf_load_stackoverflow)
JP (1) JPH07501078A (enrdf_load_stackoverflow)
CN (1) CN1073946A (enrdf_load_stackoverflow)
AU (1) AU661362B2 (enrdf_load_stackoverflow)
CA (1) CA2123128A1 (enrdf_load_stackoverflow)
CZ (1) CZ124494A3 (enrdf_load_stackoverflow)
FI (1) FI942345A7 (enrdf_load_stackoverflow)
HU (1) HUT67937A (enrdf_load_stackoverflow)
IL (1) IL103817A0 (enrdf_load_stackoverflow)
MX (1) MX9206628A (enrdf_load_stackoverflow)
NO (1) NO941905L (enrdf_load_stackoverflow)
NZ (1) NZ245207A (enrdf_load_stackoverflow)
PT (1) PT101079A (enrdf_load_stackoverflow)
SI (1) SI9200332A (enrdf_load_stackoverflow)
SK (1) SK59294A3 (enrdf_load_stackoverflow)
TW (1) TW232697B (enrdf_load_stackoverflow)
WO (1) WO1993010127A1 (enrdf_load_stackoverflow)

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US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
JP2003523396A (ja) * 2000-02-25 2003-08-05 ノボ ノルディスク アクティーゼルスカブ ベータ細胞変性の抑制
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US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
WO2005047297A1 (en) * 2003-11-12 2005-05-26 Phenomix Corporation Heterocyclic boronic acid compounds
CA2545641A1 (en) 2003-11-17 2005-06-02 Novartis Ag Use of organic compounds
SI3366283T1 (sl) 2004-01-20 2021-12-31 Novartis Ag Formulacija za neposredno stiskanje in postopek
AR049631A1 (es) * 2004-04-27 2006-08-23 Wyeth Corp Proceso de acoplamiento para la generacion de derivados reactivos de pirrol -2- carbonitrilo n- sustituidos con contenido de boro para producir biarilos
DOP2006000008A (es) 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
CA2606785A1 (en) 2005-05-19 2006-11-23 Genentech, Inc. Fibroblast activation protein inhibitor compounds and methods
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (zh) * 2005-10-18 2007-08-15 武汉大学 光活性β－羟基酮的制备方法
BRPI0620027A2 (pt) 2005-12-19 2011-10-25 Tufts College inibidores da protease soft e formas pró-soft
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UA97479C2 (ru) 2006-04-11 2012-02-27 Арена Фармасьютикалз, Инк. Применение g-белок-связанного рецептора (gpcr) для идентификации средств, которые усиливают секрецию глюкозозависимого инсулинотропного пептида (gi)
EP2146210A1 (en) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY
SI2318419T1 (sl) * 2008-06-17 2015-07-31 Millennium Pharmaceuticals, Inc. Spojine boronat estra in njihovi farmacevtski sestavki
AR077642A1 (es) 2009-07-09 2011-09-14 Arena Pharm Inc Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
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BR112017019170A2 (pt) 2015-03-09 2018-07-10 Intekrin Therapeutics, Inc. métodos para o tratamento de doença do fígado gorduroso não alcoólico e / ou lipodistrofia
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CN108047257B (zh) * 2017-12-17 2020-03-13 沧州普瑞东方科技有限公司 一种手性n-boc-吡咯烷-2-硼酸的制备工艺
WO2019163738A1 (en) * 2018-02-20 2019-08-29 Otsuka Pharmaceutical Co., Ltd. Method of 4-boronophenylalanine production
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US4935493A (en) * 1987-10-06 1990-06-19 E. I. Du Pont De Nemours And Company Protease inhibitors
CA2080474A1 (en) * 1990-04-14 1991-10-15 William W. Bachovchin Inhibitors of dipeptidyl-aminopeptidase type iv
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry

Also Published As

Publication number Publication date
FI942345A0 (fi) 1994-05-20
JPH07501078A (ja) 1995-02-02
TW232697B (enrdf_load_stackoverflow) 1994-10-21
SI9200332A (en) 1993-06-30
MX9206628A (es) 1993-05-01
NO941905D0 (no) 1994-05-20
HU9401350D0 (en) 1994-08-29
SK59294A3 (en) 1995-02-08
AU661362B2 (en) 1995-07-20
HUT67937A (en) 1995-05-29
CZ124494A3 (en) 1995-07-12
PT101079A (pt) 1994-02-28
NZ245207A (en) 1994-07-26
WO1993010127A1 (en) 1993-05-27
NO941905L (no) 1994-07-14
CN1073946A (zh) 1993-07-07
CA2123128A1 (en) 1993-05-27
AU3136893A (en) 1993-06-15
FI942345A7 (fi) 1994-05-20
EP0641347A1 (en) 1995-03-08

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