IL101882A0 - Benzofuran derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Benzofuran derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL101882A0 IL101882A0 IL101882A IL10188292A IL101882A0 IL 101882 A0 IL101882 A0 IL 101882A0 IL 101882 A IL101882 A IL 101882A IL 10188292 A IL10188292 A IL 10188292A IL 101882 A0 IL101882 A0 IL 101882A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- benzofuran derivatives
- benzofuran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919110636A GB9110636D0 (en) | 1991-05-16 | 1991-05-16 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL101882A0 true IL101882A0 (en) | 1992-12-30 |
Family
ID=10695121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL101882A IL101882A0 (en) | 1991-05-16 | 1992-05-15 | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5332831A (ja) |
| EP (1) | EP0514198B1 (ja) |
| JP (1) | JPH06211846A (ja) |
| KR (1) | KR920021541A (ja) |
| AP (1) | AP318A (ja) |
| AT (1) | ATE169297T1 (ja) |
| AU (2) | AU1692692A (ja) |
| BG (1) | BG98216A (ja) |
| CA (1) | CA2068766A1 (ja) |
| CZ (1) | CZ243093A3 (ja) |
| DE (1) | DE69226472D1 (ja) |
| FI (1) | FI935036A0 (ja) |
| GB (1) | GB9110636D0 (ja) |
| IL (1) | IL101882A0 (ja) |
| IS (1) | IS1609B (ja) |
| MX (1) | MX9202281A (ja) |
| NO (1) | NO921944L (ja) |
| OA (1) | OA09841A (ja) |
| SK (1) | SK112893A3 (ja) |
| TW (1) | TW221998B (ja) |
| WO (1) | WO1992020674A1 (ja) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9218449D0 (en) | 1992-08-29 | 1992-10-14 | Boots Co Plc | Therapeutic agents |
| US5336779A (en) * | 1992-10-08 | 1994-08-09 | Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha | Method of producing formylimidazoles |
| DE69624253T2 (de) * | 1995-10-06 | 2003-08-07 | Novartis Ag, Basel | Ati-rezeptorantagonisten zur verhinderung und behandlung des postischemischen nervenversagens und zum schutze ischemischer nieren |
| AU1791497A (en) | 1996-02-29 | 1997-09-16 | Novartis Ag | At1 receptor antagonist for the stimulation of apoptosis |
| KR100567183B1 (ko) * | 1997-11-14 | 2006-06-13 | 론자 아게 | 포르밀이미다졸의제조방법 |
| TR200605472T1 (tr) | 1998-12-23 | 2007-02-21 | Novartis Ag | AT-1 veya AT-2 reseptörlerindeki artışın neden olduğu hastalıkların tedavisi için AT-1 reseptör antagonisti veya AT-2 reseptör modülatörünün kullanımı@ |
| US6465502B1 (en) | 1998-12-23 | 2002-10-15 | Novartis Ag | Additional therapeutic use |
| CN101011390A (zh) | 1999-01-26 | 2007-08-08 | 诺瓦提斯公司 | 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用 |
| US6211217B1 (en) | 1999-03-16 | 2001-04-03 | Novartis Ag | Method for reducing pericardial fibrosis and adhesion formation |
| EP1867342A1 (en) * | 1999-07-21 | 2007-12-19 | Takeda Pharmaceutical Company Limited | Agents for ameliorating troubles following cerebrovascular failure and inhibiting progress thereof |
| SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| AU2001285442A1 (en) * | 2000-08-17 | 2002-02-25 | Gliatech, Inc. | Novel alicyclic imidazoles as H3 agents |
| DE10335027A1 (de) | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| KR101476582B1 (ko) * | 2006-05-05 | 2014-12-24 | 다우 글로벌 테크놀로지스 엘엘씨 | 헤테로시클릭 유기 리간드의 하프늄 착물 |
| CN101511796B (zh) | 2006-09-05 | 2012-05-09 | 协和发酵麒麟株式会社 | 咪唑衍生物 |
| EP1908469A1 (en) | 2006-10-06 | 2008-04-09 | Boehringer Ingelheim Vetmedica Gmbh | Angiotensin II receptor antagonist for the treatment of systemic diseases in cats |
| JP5072675B2 (ja) | 2007-04-03 | 2012-11-14 | 四国化成工業株式会社 | ２−ハロイミダゾール化合物の製造方法 |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| WO2009149279A2 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
| KR20200026975A (ko) | 2017-07-07 | 2020-03-11 | 베링거잉겔하임베트메디카게엠베하 | 고양이에서 전신 질환의 예방 또는 치료를 위한 안지오텐신 ii 수용체 길항제 |
| CN110256382A (zh) * | 2019-06-06 | 2019-09-20 | 武汉药明康德新药开发有限公司 | 一种2-(5-甲基苯并呋喃-2-基)苯甲腈的合成方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1389827A (en) * | 1971-07-23 | 1975-04-09 | Fisons Ltd | Tetrazolyl benzopyrans |
| JPS54148788A (en) * | 1978-05-15 | 1979-11-21 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation |
| US4526896A (en) * | 1978-12-26 | 1985-07-02 | Riker Laboratories, Inc. | Tetrazol-5-yl 2-nitro-3-phenylbenzofurans and antimicrobial use thereof |
| JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
| JPS5671073A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | Imidazole derivative |
| ZA824343B (en) * | 1981-07-01 | 1983-04-27 | Upjohn Co | Pyridinyl- and imidazolyl-benzofurane and benzothiophenes |
| JPS6163671A (ja) * | 1984-09-05 | 1986-04-01 | Shionogi & Co Ltd | ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤 |
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| US4916129A (en) * | 1989-01-19 | 1990-04-10 | E. I. Du Pont De Nemours And Company | Combination β-blocking/angiotensin II blocking antihypertensives |
| DK0403159T3 (da) * | 1989-06-14 | 2000-08-14 | Smithkline Beecham Corp | Imidazolylalkensyrer |
| SG50669A1 (en) * | 1989-06-30 | 1998-07-20 | Du Pont | Fused-ring aryl subtituted imidazoles |
| WO1991000277A1 (en) * | 1989-06-30 | 1991-01-10 | E.I. Du Pont De Nemours And Company | Substituted imidazoles |
| JPH03204875A (ja) * | 1989-10-03 | 1991-09-06 | Wakamoto Pharmaceut Co Ltd | テトラゾール酢酸誘導体、及び該誘導体を有効成分とするアルドースレダクターゼ阻害剤 |
| AU640417B2 (en) * | 1989-10-25 | 1993-08-26 | Smithkline Beecham Corporation | Substituted 5-((tetrazolyl)alkenyl)imidazoles |
| CA2028925A1 (en) * | 1989-11-06 | 1991-05-07 | Gerald R. Girard | Substituted n-(imidazolyl)alkyl alanine derivatives |
| GB8927277D0 (en) * | 1989-12-01 | 1990-01-31 | Glaxo Group Ltd | Chemical compounds |
| US5190942A (en) * | 1991-04-22 | 1993-03-02 | E. R. Squibb & Sons, Inc. | Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives |
| WO1992020679A1 (en) * | 1991-05-16 | 1992-11-26 | Glaxo Group Limited | Benzofuran derivatives |
| DE4140519A1 (de) * | 1991-12-09 | 1993-06-17 | Merck Patent Gmbh | Benzofurane |
-
1991
- 1991-05-16 GB GB919110636A patent/GB9110636D0/en active Pending
-
1992
- 1992-05-15 US US07/883,378 patent/US5332831A/en not_active Expired - Fee Related
- 1992-05-15 MX MX9202281A patent/MX9202281A/es unknown
- 1992-05-15 CA CA002068766A patent/CA2068766A1/en not_active Abandoned
- 1992-05-15 NO NO92921944A patent/NO921944L/no unknown
- 1992-05-15 IS IS3865A patent/IS1609B/is unknown
- 1992-05-15 IL IL101882A patent/IL101882A0/xx unknown
- 1992-05-15 AP AP9200389A patent/AP318A/en active
- 1992-05-15 DE DE69226472T patent/DE69226472D1/de not_active Expired - Lifetime
- 1992-05-15 EP EP92304420A patent/EP0514198B1/en not_active Expired - Lifetime
- 1992-05-15 WO PCT/GB1992/000888 patent/WO1992020674A1/en not_active Application Discontinuation
- 1992-05-15 KR KR1019920008241A patent/KR920021541A/ko not_active Application Discontinuation
- 1992-05-15 AT AT92304420T patent/ATE169297T1/de not_active IP Right Cessation
- 1992-05-15 SK SK1128-93A patent/SK112893A3/sk unknown
- 1992-05-15 AU AU16926/92A patent/AU1692692A/en not_active Abandoned
- 1992-05-15 JP JP4148890A patent/JPH06211846A/ja active Pending
- 1992-05-15 CZ CS932430A patent/CZ243093A3/cs unknown
- 1992-05-15 TW TW081103782A patent/TW221998B/zh active
- 1992-05-15 AU AU16321/92A patent/AU654350B2/en not_active Ceased
-
1993
- 1993-10-08 OA OA60424A patent/OA09841A/en unknown
- 1993-11-12 BG BG98216A patent/BG98216A/xx unknown
- 1993-11-15 FI FI935036A patent/FI935036A0/fi not_active Application Discontinuation
-
1994
- 1994-03-31 US US08/220,698 patent/US5498722A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW221998B (ja) | 1994-04-01 |
| AU1632192A (en) | 1993-03-11 |
| EP0514198A1 (en) | 1992-11-19 |
| CA2068766A1 (en) | 1992-11-17 |
| WO1992020674A1 (en) | 1992-11-26 |
| ATE169297T1 (de) | 1998-08-15 |
| FI935036A (fi) | 1993-11-15 |
| KR920021541A (ko) | 1992-12-18 |
| DE69226472D1 (de) | 1998-09-10 |
| GB9110636D0 (en) | 1991-07-03 |
| FI935036A0 (fi) | 1993-11-15 |
| IS1609B (is) | 1996-10-18 |
| NO921944D0 (no) | 1992-05-15 |
| US5332831A (en) | 1994-07-26 |
| EP0514198B1 (en) | 1998-08-05 |
| CZ243093A3 (en) | 1994-03-16 |
| AU654350B2 (en) | 1994-11-03 |
| BG98216A (en) | 1994-08-15 |
| IS3865A (is) | 1992-11-17 |
| SK112893A3 (en) | 1994-11-09 |
| US5498722A (en) | 1996-03-12 |
| AU1692692A (en) | 1992-12-30 |
| NO921944L (no) | 1992-11-17 |
| MX9202281A (es) | 1992-11-01 |
| AP318A (en) | 1994-02-15 |
| JPH06211846A (ja) | 1994-08-02 |
| OA09841A (en) | 1994-08-15 |
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| IL98756A0 (en) | Pharmaceutical compositions containing benzeneacetamid derivatives,certain such novel compounds and their preparation | |
| IL108703A0 (en) | Substituted azolone derivatives, their preparation and pharmaceutical compositions containing them | |
| IL103020A0 (en) | Imidazopyridine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101888A0 (en) | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them | |
| IL97501A0 (en) | 4-pyridone derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102500A0 (en) | 3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL107302A0 (en) | Benzofuran derivatives, their preparation and pharmaceutical compositions comprising them | |
| IL104042A0 (en) | Substituted diphenylsulfides,their preparation and pharmaceutical compositions containing them | |
| IL103980A0 (en) | Substituted phthalides and heterocyclic phthalides,their preparation and pharmaceutical compositions containing them |