IE33337B1 - Propionic acid derivatives and manufacture thereof - Google Patents
Propionic acid derivatives and manufacture thereofInfo
- Publication number
- IE33337B1 IE33337B1 IE1401/69A IE140169A IE33337B1 IE 33337 B1 IE33337 B1 IE 33337B1 IE 1401/69 A IE1401/69 A IE 1401/69A IE 140169 A IE140169 A IE 140169A IE 33337 B1 IE33337 B1 IE 33337B1
- Authority
- IE
- Ireland
- Prior art keywords
- phenyl
- salts
- propionic acid
- cyclohexenyl
- manufacture
- Prior art date
Links
- 229940111131 antiinflammatory and antirheumatic product propionic acid derivative Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000005599 propionic acid derivatives Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- RQEUFEKYXDPUSK-UHFFFAOYSA-N 1-phenylethylamine Chemical compound CC(N)C1=CC=CC=C1 RQEUFEKYXDPUSK-UHFFFAOYSA-N 0.000 abstract 1
- CVBPQTZKZQWEFX-UHFFFAOYSA-N 2-[4-(cyclohexen-1-yl)phenyl]propanoic acid Chemical compound C1=CC(C(C(O)=O)C)=CC=C1C1=CCCCC1 CVBPQTZKZQWEFX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- KMPWYEUPVWOPIM-KODHJQJWSA-N cinchonidine Chemical compound C1=CC=C2C([C@H]([C@H]3[N@]4CC[C@H]([C@H](C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-KODHJQJWSA-N 0.000 abstract 1
- KMPWYEUPVWOPIM-UHFFFAOYSA-N cinchonidine Natural products C1=CC=C2C(C(C3N4CCC(C(C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/14—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE158/73A IE33338B1 (en) | 1968-10-11 | 1969-10-10 | Alpha-phenylalkyl halides and cyanides and manufacture thereof |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1524068A CH529086A (de) | 1968-10-11 | 1968-10-11 | Verfahren zur Herstellung neuer a-Phenylcarbonsäuren |
| CH1656968A CH559159A5 (en) | 1968-11-06 | 1968-11-06 | Analgesic anti-inflammatory alpha-phenyl fatty acids |
| CH708369 | 1969-05-08 | ||
| CH1270569 | 1969-08-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33337L IE33337L (en) | 1970-04-11 |
| IE33337B1 true IE33337B1 (en) | 1974-05-29 |
Family
ID=27429043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1401/69A IE33337B1 (en) | 1968-10-11 | 1969-10-10 | Propionic acid derivatives and manufacture thereof |
Country Status (12)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54344U (enrdf_load_stackoverflow) * | 1977-06-03 | 1979-01-05 |
-
1969
- 1969-09-25 GB GB47182/69A patent/GB1283367A/en not_active Expired
- 1969-09-25 CY CY794A patent/CY794A/xx unknown
- 1969-09-30 SE SE6913428A patent/SE372253B/xx unknown
- 1969-10-09 FR FR6934526A patent/FR2020394B1/fr not_active Expired
- 1969-10-09 OA OA53748A patent/OA03603A/xx unknown
- 1969-10-10 BE BE740099D patent/BE740099A/xx unknown
- 1969-10-10 NL NL6915401A patent/NL6915401A/xx unknown
- 1969-10-10 AT AT956769A patent/AT299923B/de not_active IP Right Cessation
- 1969-10-10 IE IE1401/69A patent/IE33337B1/xx unknown
- 1969-10-10 DK DK540069A patent/DK133239C/da active
-
1972
- 1972-03-02 JP JP47021112A patent/JPS4935616B1/ja active Pending
- 1972-03-02 JP JP47021109A patent/JPS4935615B1/ja active Pending
- 1972-03-02 JP JP47021111A patent/JPS5033055B1/ja active Pending
- 1972-03-02 JP JP47021110A patent/JPS5033054B1/ja active Pending
-
1975
- 1975-12-30 MY MY90/75A patent/MY7500090A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY794A (en) | 1976-12-01 |
| DE1950054B2 (de) | 1975-07-10 |
| DK133239B (da) | 1976-04-12 |
| DK133239C (da) | 1976-10-11 |
| DE1950054A1 (de) | 1970-04-16 |
| GB1283367A (en) | 1972-07-26 |
| SE372253B (enrdf_load_stackoverflow) | 1974-12-16 |
| JPS4935616B1 (enrdf_load_stackoverflow) | 1974-09-25 |
| JPS5033054B1 (enrdf_load_stackoverflow) | 1975-10-27 |
| NL6915401A (enrdf_load_stackoverflow) | 1970-04-14 |
| JPS4935615B1 (enrdf_load_stackoverflow) | 1974-09-25 |
| MY7500090A (en) | 1975-12-31 |
| FR2020394B1 (enrdf_load_stackoverflow) | 1974-02-01 |
| AT299923B (de) | 1972-07-10 |
| FR2020394A1 (enrdf_load_stackoverflow) | 1970-07-10 |
| IE33337L (en) | 1970-04-11 |
| OA03603A (fr) | 1971-03-30 |
| JPS5033055B1 (enrdf_load_stackoverflow) | 1975-10-27 |
| BE740099A (enrdf_load_stackoverflow) | 1970-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU6776887A (en) | Fluid therapy with l-lactate and/or pyruvate anions | |
| IE36607L (en) | 2 - amino -2', 6' - propionoxylidide | |
| GB1224989A (en) | Meat flavoured products | |
| BG47648A3 (en) | Method for preparing of triazolyl quanolinic compounds | |
| ES375203A1 (es) | Un procedimiento para preparar un derivado de benzotiazepi-na. | |
| IE33337B1 (en) | Propionic acid derivatives and manufacture thereof | |
| IE35507B1 (en) | Anti-inflammatory preparations containing tetrahydrocarbazole derivatives | |
| GB1349138A (en) | Quinazoline derivative | |
| IE45418L (en) | Thiazole derivative | |
| GB1204809A (en) | Novel quinoline derivatives, the preparation thereof and compositions containing the same | |
| GB1246117A (en) | Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture | |
| GB1416855A (en) | Disazo pigments and a process for their manufacture and use | |
| IE34275L (en) | Alpha-hydrazino acids | |
| GB1197389A (en) | Heterocyclic Dithiocarboxylic Acids | |
| ES377523A1 (es) | Un procedimiento para fabricar una sustancia combinada, compuesta de acido germanico y cisteina. | |
| GB1176721A (en) | 0-Cyclopentenecarboxylic Acids and Process for their Manufacture | |
| GB1312196A (en) | Nicotinic acid derivatives and a process for the manufacture thereof | |
| IE34386L (en) | Acetylsalicylic acid-containing composition | |
| GB1501839A (en) | Pharmaceutical compositions for the inhibition of thrombocyte aggregation | |
| IE34348B1 (en) | Esters of rho-biphenylylacetic acid | |
| GB1228080A (enrdf_load_stackoverflow) | ||
| IE36255B1 (en) | A tripeptide and acid addition salts thereof and a process for the manufacture of same | |
| GB1301456A (enrdf_load_stackoverflow) | ||
| GB1268783A (en) | Benzodiazepine derivatives | |
| IE35040L (en) | Manufacture of propionic acid |