HUT62706A - Hepatitis c virus /hcv/ antigen preparations in immunoassays applying anti-hcv antibodies - Google Patents

Hepatitis c virus /hcv/ antigen preparations in immunoassays applying anti-hcv antibodies

Info

Publication number
HUT62706A
HUT62706A HU923146A HUP9203146A HUT62706A HU T62706 A HUT62706 A HU T62706A HU 923146 A HU923146 A HU 923146A HU P9203146 A HUP9203146 A HU P9203146A HU T62706 A HUT62706 A HU T62706A
Authority
HU
Hungary
Prior art keywords
hcv
domain
antigen
immunoassays
hepatitis
Prior art date
Application number
HU923146A
Other languages
English (en)
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24005897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUT62706(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of HU9203146D0 publication Critical patent/HU9203146D0/hu
Publication of HUT62706A publication Critical patent/HUT62706A/hu
Publication of HU217025B publication Critical patent/HU217025B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Thermistors And Varistors (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU9203146A 1990-04-04 1991-03-29 Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben HU217025B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50435290A 1990-04-04 1990-04-04

Publications (3)

Publication Number Publication Date
HU9203146D0 HU9203146D0 (en) 1992-12-28
HUT62706A true HUT62706A (en) 1993-05-28
HU217025B HU217025B (hu) 1999-11-29

Family

ID=24005897

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9203146A HU217025B (hu) 1990-04-04 1991-03-29 Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben

Country Status (25)

Country Link
EP (2) EP0450931B1 (hu)
JP (1) JP2733138B2 (hu)
KR (1) KR100206150B1 (hu)
AT (2) ATE182684T1 (hu)
BG (1) BG61291B1 (hu)
BR (1) BR9106309A (hu)
CY (1) CY1881A (hu)
DE (2) DE69120138T2 (hu)
DK (2) DK0693687T4 (hu)
ES (2) ES2088465T3 (hu)
FI (1) FI106317B (hu)
GB (1) GB2257784B (hu)
GR (2) GR3020964T3 (hu)
HU (1) HU217025B (hu)
IE (1) IE911105A1 (hu)
IL (2) IL97741A0 (hu)
LT (1) LT3808B (hu)
LV (2) LV10344A (hu)
MY (1) MY107499A (hu)
NO (1) NO310241B1 (hu)
PL (1) PL172133B1 (hu)
RO (1) RO109916B1 (hu)
RU (1) RU2130969C1 (hu)
UA (1) UA41266C2 (hu)
WO (1) WO1991015771A1 (hu)

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US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DE69131882T3 (de) * 1990-11-08 2007-05-24 Novartis Vaccines and Diagnostics, Inc., Emeryville Asiloglycoproteine des hepatitis c-virus
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
ES2138784T3 (es) * 1990-12-14 2000-01-16 Innogenetics Nv Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
DE4041304A1 (de) * 1990-12-21 1992-06-25 Mikrogen Molekularbiol Entw Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
AU3063992A (en) * 1991-11-07 1993-06-07 Dade International Inc. Epitope mapping ot the c33c region of hcv
WO1993010239A2 (en) * 1991-11-21 1993-05-27 Common Services Agency Hepatitis-c virus testing
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UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
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WO1994013164A1 (en) 1992-12-10 1994-06-23 Nike International Ltd. Bonding of rubber to plastic in footwear
DE69434117T3 (de) 1993-05-10 2009-10-08 Novartis Vaccines and Diagnostics, Inc.(n.d.Ges.d.Staates Delaware), Emeryville Verfahren zur typisierung von hepatitis c viren und dafür zu verwendende reagenzien
DE4428705A1 (de) 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
JPH0862219A (ja) * 1994-08-19 1996-03-08 Dainabotsuto Kk 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法
JP3665371B2 (ja) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 Ｃ型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法
CA2172305A1 (en) * 1995-03-30 1996-10-01 Muneo Aoyama Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides
WO1996037606A1 (en) * 1995-05-22 1996-11-28 Bionova Corporation Compositions and methods for the diagnosis of, and vaccination against, hepatitis c virus (hcv)
FR2734639B1 (fr) * 1995-05-26 1997-10-03 Parteurop Methode de pronostic de l'evolution d'une infection par le virus de l'hepatite c, et necessaire pour sa mise en oeuvre
FR2737209B1 (fr) 1995-07-25 1997-09-19 Bio Merieux Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
US6127116A (en) 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
WO1999015898A1 (en) * 1997-09-22 1999-04-01 Chiron Corporation Method for detecting antibodies in a sample
JP2003512598A (ja) * 1999-07-15 2003-04-02 デパートマント、アヴ、ヘルス、アンド、ヒューマン、サーヴィセズ Ｃ型肝炎に続く肝不全の予測
WO2001030812A2 (en) 1999-10-27 2001-05-03 Chiron Corporation Activation of hcv-specific t cells
KR100788812B1 (ko) * 1999-11-24 2007-12-27 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 신규한 ｈｃｖ 비구조 폴리펩티드
US6986892B1 (en) 1999-11-24 2006-01-17 Chiron Corporation Immunogenic Hepatitis C virus non-structural polypeptides
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
SI1354204T2 (sl) * 2000-06-15 2010-09-30 Novartis Vaccines & Diagnostic Hcv antigen antitelo kombinacijska analiza
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
ATE517184T1 (de) 2000-08-17 2011-08-15 Tripep Ab Hcv ns3/4a kodierende nukleinsäure
RU2286172C2 (ru) 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
FR2839722A1 (fr) 2002-05-17 2003-11-21 Bio Merieux Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c
US7166426B2 (en) 2002-09-09 2007-01-23 Novartis Vaccines And Diagnostics, Inc. HCV assay
WO2005123952A2 (en) 2004-06-09 2005-12-29 Pathogen Removal And Diagnostic Technologies Inc. Particles embedded ina porous substrate for removing target analyte from a sample
JP4005093B2 (ja) * 2005-05-25 2007-11-07 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬および抗ｈｃｖ抗体検出方法
JP2005274584A (ja) * 2005-05-25 2005-10-06 Sysmex Corp Ｃ型肝炎ウイルス感染症診断薬の製造方法
CA2618429A1 (en) 2005-05-25 2007-03-22 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
MX2008011361A (es) * 2006-03-09 2008-09-15 Transgene Sa Proteina de fusion no-estructural del virus de hepatitis c.
US20080227111A1 (en) 2007-03-16 2008-09-18 Sysmex Corporation Reagent kit and method for measuring hcv antibody
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
WO2009130588A2 (en) 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
JP6821562B2 (ja) 2014-10-29 2021-01-27 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｎｓ３捕捉ペプチドを使用して対象の抗ｈｃｖ抗体を検出するアッセイ
JP2018124277A (ja) * 2017-02-02 2018-08-09 三洋化成工業株式会社 粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法

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BR9006422A (pt) * 1989-12-18 1991-09-24 Wellcome Found Processo para preparar um polipeptidio viral pt-nanbh e processo para detectar o mesmo
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Also Published As

Publication number Publication date
DK0450931T3 (da) 1996-07-01
CY1881A (en) 1996-04-05
DE69120138T2 (de) 1996-11-14
BG96943A (bg) 1993-12-24
NO310241B1 (no) 2001-06-11
ATE139343T1 (de) 1996-06-15
UA41266C2 (uk) 2001-09-17
EP0693687A1 (en) 1996-01-24
LV10344A (en) 1994-10-20
JP2733138B2 (ja) 1998-03-30
NO923839D0 (no) 1992-10-01
LT3808B (en) 1996-03-25
LV10344B (en) 1996-02-20
EP0450931B1 (en) 1996-06-12
HU9203146D0 (en) 1992-12-28
GR3020964T3 (en) 1996-12-31
FI924349A (fi) 1992-09-28
RU2130969C1 (ru) 1999-05-27
KR100206150B1 (ko) 1999-07-01
BG61291B1 (en) 1997-04-30
ES2134388T3 (es) 1999-10-01
FI924349A0 (fi) 1992-09-28
GB2257784A (en) 1993-01-20
AU7651091A (en) 1991-10-30
HU217025B (hu) 1999-11-29
ES2088465T3 (es) 1996-08-16
GB2257784B (en) 1995-01-04
ATE182684T1 (de) 1999-08-15
IE911105A1 (en) 1991-10-09
LTIP1747A (en) 1995-07-25
DK0693687T4 (da) 2008-09-22
GB9220480D0 (en) 1992-11-25
ES2134388T5 (es) 2008-12-01
NO923839L (no) 1992-11-19
DE69131488T2 (de) 1999-11-18
EP0693687B2 (en) 2008-06-04
IL97741A0 (en) 1992-06-21
RO109916B1 (ro) 1995-07-28
FI106317B (fi) 2001-01-15
IL170719A (en) 2011-04-28
PL172133B1 (pl) 1997-08-29
DE69120138D1 (de) 1996-07-18
DK0693687T3 (da) 1999-11-29
EP0450931A1 (en) 1991-10-09
AU639560B2 (en) 1993-07-29
DE69131488D1 (de) 1999-09-02
GR3031361T3 (en) 2000-01-31
EP0693687B1 (en) 1999-07-28
BR9106309A (pt) 1993-04-20
WO1991015771A1 (en) 1991-10-17
JPH05508219A (ja) 1993-11-18
MY107499A (en) 1995-12-30

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