HUP9901990A2 - Furan- and thiophene derivatives having inhibitor effect on the replication of hiv-1 and hiv-1 mutants, and medicaments containing the same - Google Patents
Furan- and thiophene derivatives having inhibitor effect on the replication of hiv-1 and hiv-1 mutants, and medicaments containing the sameInfo
- Publication number
- HUP9901990A2 HUP9901990A2 HU9901990A HUP9901990A HUP9901990A2 HU P9901990 A2 HUP9901990 A2 HU P9901990A2 HU 9901990 A HU9901990 A HU 9901990A HU P9901990 A HUP9901990 A HU P9901990A HU P9901990 A2 HUP9901990 A2 HU P9901990A2
- Authority
- HU
- Hungary
- Prior art keywords
- hiv
- mutants
- furan
- replication
- same
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- WCZBUQIZTSIQFE-UHFFFAOYSA-N furan;thiophene Chemical class C=1C=COC=1.C=1C=CSC=1 WCZBUQIZTSIQFE-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000010076 replication Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/565,493 US5696151A (en) | 1995-11-30 | 1995-11-30 | Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants |
PCT/US1996/018394 WO1997019940A1 (en) | 1995-11-30 | 1996-11-15 | Furan- and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of the replication of hiv-1 and hiv-1 mutants |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9901990A2 true HUP9901990A2 (en) | 2000-07-28 |
HUP9901990A3 HUP9901990A3 (en) | 2000-08-28 |
HU223660B1 HU223660B1 (hu) | 2004-11-29 |
Family
ID=24258853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9901990A HU223660B1 (hu) | 1995-11-30 | 1996-11-15 | HIV-1 és HIV-1 mutánsok replikációjának gátlására használható furán- és tiofénszármazékok és ezeket tartalmazó gyógyszerkészítmények |
Country Status (21)
Country | Link |
---|---|
US (1) | US5696151A (hu) |
EP (1) | EP0874839B1 (hu) |
JP (1) | JP3027771B2 (hu) |
KR (1) | KR100505841B1 (hu) |
CN (1) | CN1098847C (hu) |
AP (1) | AP902A (hu) |
AT (1) | ATE224382T1 (hu) |
AU (1) | AU704086B2 (hu) |
BR (1) | BR9611838A (hu) |
CA (1) | CA2237194C (hu) |
DE (1) | DE69623819T2 (hu) |
DK (1) | DK0874839T3 (hu) |
ES (1) | ES2183986T3 (hu) |
HK (1) | HK1016601A1 (hu) |
HU (1) | HU223660B1 (hu) |
NZ (1) | NZ324118A (hu) |
OA (1) | OA10864A (hu) |
PT (1) | PT874839E (hu) |
TW (1) | TW448169B (hu) |
WO (1) | WO1997019940A1 (hu) |
ZA (1) | ZA969490B (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6017947A (en) * | 1999-09-17 | 2000-01-25 | Brouwer; Walter Gerhard | Heterocyclic carbodithioperoxyimidic compounds useful for the inhibition of the replication of HIV |
US6143780A (en) * | 1999-09-17 | 2000-11-07 | Uniroyal Chemical Company, Inc. | N-arylmethylthioanilide compounds useful for the inhibition of the replication of HIV |
US7064139B2 (en) * | 2001-10-29 | 2006-06-20 | Uniroyal Chemical Company, Inc. | Method for treating retroviral infections |
US6498254B1 (en) * | 2001-10-29 | 2002-12-24 | Uniroyal Chemical Company, Inc. | Antiretroviral compounds and compositions |
DE102008015033A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung |
DE102008015032A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte Pyrazolamide und ihre Verwendung |
DE102008062863A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung |
DE102008062878A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte Furancarboxamide und ihre Verwendung |
CN101987842A (zh) * | 2009-07-31 | 2011-03-23 | 上海开拓者医药发展有限公司 | 一种2-甲基噻吩衍生物的制备方法 |
US10246420B2 (en) | 2014-07-24 | 2019-04-02 | Bayer Cropscience Aktiengesellschaft | Pyrazole derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268389A (en) * | 1989-10-16 | 1993-12-07 | Uniroyal Chemical Company, Inc. | Thiocarboxylate ester compounds compositions containing the same |
US5968910A (en) * | 1994-11-30 | 1999-10-19 | Jan M. R. Balzarini | Compositions containing two or three inhibitors of different HIV reverse transcriptases |
-
1995
- 1995-11-30 US US08/565,493 patent/US5696151A/en not_active Expired - Lifetime
-
1996
- 1996-11-08 TW TW085113662A patent/TW448169B/zh not_active IP Right Cessation
- 1996-11-12 ZA ZA969490A patent/ZA969490B/xx unknown
- 1996-11-15 JP JP9520533A patent/JP3027771B2/ja not_active Expired - Lifetime
- 1996-11-15 NZ NZ324118A patent/NZ324118A/xx not_active IP Right Cessation
- 1996-11-15 AU AU11199/97A patent/AU704086B2/en not_active Expired
- 1996-11-15 AP APAP/P/1998/001245A patent/AP902A/en active
- 1996-11-15 BR BR9611838A patent/BR9611838A/pt active Search and Examination
- 1996-11-15 EP EP96942010A patent/EP0874839B1/en not_active Expired - Lifetime
- 1996-11-15 CN CN96198705A patent/CN1098847C/zh not_active Expired - Lifetime
- 1996-11-15 AT AT96942010T patent/ATE224382T1/de active
- 1996-11-15 WO PCT/US1996/018394 patent/WO1997019940A1/en active IP Right Grant
- 1996-11-15 PT PT96942010T patent/PT874839E/pt unknown
- 1996-11-15 KR KR10-1998-0703958A patent/KR100505841B1/ko active IP Right Grant
- 1996-11-15 DK DK96942010T patent/DK0874839T3/da active
- 1996-11-15 ES ES96942010T patent/ES2183986T3/es not_active Expired - Lifetime
- 1996-11-15 CA CA002237194A patent/CA2237194C/en not_active Expired - Lifetime
- 1996-11-15 HU HU9901990A patent/HU223660B1/hu active IP Right Grant
- 1996-11-15 DE DE69623819T patent/DE69623819T2/de not_active Expired - Lifetime
-
1998
- 1998-05-29 OA OA9800070A patent/OA10864A/en unknown
-
1999
- 1999-04-21 HK HK99101720A patent/HK1016601A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH11504657A (ja) | 1999-04-27 |
ATE224382T1 (de) | 2002-10-15 |
DE69623819D1 (de) | 2002-10-24 |
BR9611838A (pt) | 1999-03-09 |
KR100505841B1 (ko) | 2005-12-14 |
JP3027771B2 (ja) | 2000-04-04 |
CN1203596A (zh) | 1998-12-30 |
WO1997019940A1 (en) | 1997-06-05 |
OA10864A (en) | 2003-02-18 |
EP0874839B1 (en) | 2002-09-18 |
PT874839E (pt) | 2003-02-28 |
NZ324118A (en) | 1999-02-25 |
HU223660B1 (hu) | 2004-11-29 |
CA2237194A1 (en) | 1997-06-05 |
AP9801245A0 (en) | 1998-06-30 |
KR19990071682A (ko) | 1999-09-27 |
ES2183986T3 (es) | 2003-04-01 |
AU704086B2 (en) | 1999-04-15 |
DE69623819T2 (de) | 2003-05-28 |
AP902A (en) | 2000-11-23 |
ZA969490B (en) | 1997-06-02 |
CA2237194C (en) | 2006-06-13 |
EP0874839A1 (en) | 1998-11-04 |
HK1016601A1 (en) | 1999-11-05 |
CN1098847C (zh) | 2003-01-15 |
DK0874839T3 (da) | 2003-01-27 |
US5696151A (en) | 1997-12-09 |
AU1119997A (en) | 1997-06-19 |
HUP9901990A3 (en) | 2000-08-28 |
TW448169B (en) | 2001-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20041005 |