HUP0001552A2 - Mutáns Gramineae (pázsitfűfélék) fajokból származó pollenallergének, előállításuk és célzott immunterápiás alkalmazásuk - Google Patents
Mutáns Gramineae (pázsitfűfélék) fajokból származó pollenallergének, előállításuk és célzott immunterápiás alkalmazásukInfo
- Publication number
- HUP0001552A2 HUP0001552A2 HU0001552A HUP0001552A HUP0001552A2 HU P0001552 A2 HUP0001552 A2 HU P0001552A2 HU 0001552 A HU0001552 A HU 0001552A HU P0001552 A HUP0001552 A HU P0001552A HU P0001552 A2 HUP0001552 A2 HU P0001552A2
- Authority
- HU
- Hungary
- Prior art keywords
- production
- same
- pollen allergen
- specific immunotherapy
- graminae
- Prior art date
Links
- 238000009169 immunotherapy Methods 0.000 title 1
- 239000013573 pollen allergen Substances 0.000 title 1
- 239000013566 allergen Substances 0.000 abstract 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A találmány tárgyát természetes nyersanyagőkból extrakcióvalkinyerhető allergénekből származó módősítőtt, rekőmbináns allergénekképezik, tővábbá, ennek fiziőlógiásan ártalmatlan sói vagy szőlvátjai.A találmány tárgyát képezik tővábbá a találmány szerinti allergénekettartalmazó gyógyászati készítmények, alkalmazásaik, tővábbá eljárásőkaz allergének és a gyógyászati készítmények előállítására. A találmányszerinti allergének allergiák imműnspecifikűs terápiájára(hipőszenzitizációhőz) alkalmazhatók. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19713001A DE19713001A1 (de) | 1997-03-27 | 1997-03-27 | Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung |
PCT/EP1998/001507 WO1998043657A2 (de) | 1997-03-27 | 1998-03-16 | Graminaenpollenallergenmutanten zur spezifischen immuntherapie, deren herstellung und verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0001552A2 true HUP0001552A2 (hu) | 2000-09-28 |
Family
ID=7824864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001552A HUP0001552A2 (hu) | 1997-03-27 | 1998-03-16 | Mutáns Gramineae (pázsitfűfélék) fajokból származó pollenallergének, előállításuk és célzott immunterápiás alkalmazásuk |
Country Status (10)
Country | Link |
---|---|
US (1) | US6919086B1 (hu) |
EP (1) | EP1009419B1 (hu) |
JP (2) | JP4347418B2 (hu) |
AT (1) | ATE327252T1 (hu) |
DE (2) | DE19713001A1 (hu) |
ES (1) | ES2264201T3 (hu) |
HU (1) | HUP0001552A2 (hu) |
PL (1) | PL196830B1 (hu) |
PT (1) | PT1009419E (hu) |
WO (1) | WO1998043657A2 (hu) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19713001A1 (de) * | 1997-03-27 | 1998-10-01 | Merck Patent Gmbh | Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung |
AU743647B2 (en) | 1998-01-31 | 2002-01-31 | Mt. Sinai School Of Medicine Of New York University | Methods and reagents for decreasing allergic reactions |
AU3717600A (en) * | 1999-03-02 | 2000-09-21 | Board Of Trustees Of The University Of Arkansas, The | Methods and reagents for decreasing clinical reaction to allergy |
SE9903950D0 (sv) * | 1999-10-29 | 1999-10-29 | Pharmacia & Upjohn Diag Ab | Non-anaphylactic forms of grass pollen allergen and their use |
US6572859B1 (en) | 1999-10-29 | 2003-06-03 | Pharmacia Diagnostics Ab | Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use |
IT1318692B1 (it) * | 2000-09-12 | 2003-08-27 | Consiglio Nazionale Ricerche | Varianti di proteine allergeniche di phleum pratense. |
EP1373510B1 (en) * | 2000-11-16 | 2008-11-19 | Alk-Abello A/S | Mutant allergens |
AUPR779201A0 (en) * | 2001-09-20 | 2001-10-11 | University Of Melbourne, The | Immunotherapeutic and immunoprophylactic reagents |
SE0200946D0 (sv) * | 2002-03-27 | 2002-03-27 | Pharmacia Diagnostics Ab | Novel Allergen |
EP1356826A1 (en) * | 2002-04-22 | 2003-10-29 | BIOMAY Produktions- und Handels- Aktiengesellschaft | Microparticles comprising carbohydrate beads covalently linked with allergen |
MXPA05005528A (es) * | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
EP2272863B1 (de) * | 2003-06-04 | 2012-10-31 | Merck Patent GmbH | Poa p 5-Derivate mit reduzierter Allergenität und erhaltener T-Zellrealktivität |
JP5871818B2 (ja) * | 2010-01-14 | 2016-03-01 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | プロリン残基の突然変異誘発により低減したアレルゲン性を有するイネ科のグループ6アレルゲンの変異体 |
CN105061571A (zh) * | 2010-01-14 | 2015-11-18 | 默克专利股份公司 | 因脯氨酸残基突变而具有降低变应原性的真禾本科第5组变应原的变体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE216401T1 (de) * | 1989-11-03 | 2002-05-15 | Immulogic Pharma Corp | Aus hausstaub isoliertes t-zellreaktives katzenprotein, und dessen verwendungen |
DE69333709T2 (de) | 1992-08-14 | 2006-05-11 | The University Of Melbourne, Parkville | T-zell epitope des raygraspollen-allergens |
DE19713001A1 (de) * | 1997-03-27 | 1998-10-01 | Merck Patent Gmbh | Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung |
-
1997
- 1997-03-27 DE DE19713001A patent/DE19713001A1/de not_active Withdrawn
-
1998
- 1998-03-16 WO PCT/EP1998/001507 patent/WO1998043657A2/de active IP Right Grant
- 1998-03-16 PT PT98914887T patent/PT1009419E/pt unknown
- 1998-03-16 HU HU0001552A patent/HUP0001552A2/hu unknown
- 1998-03-16 DE DE59813556T patent/DE59813556D1/de not_active Expired - Lifetime
- 1998-03-16 JP JP54110298A patent/JP4347418B2/ja not_active Expired - Fee Related
- 1998-03-16 ES ES98914887T patent/ES2264201T3/es not_active Expired - Lifetime
- 1998-03-16 AT AT98914887T patent/ATE327252T1/de active
- 1998-03-16 EP EP98914887A patent/EP1009419B1/de not_active Expired - Lifetime
- 1998-03-16 US US09/381,903 patent/US6919086B1/en not_active Expired - Lifetime
- 1998-03-16 PL PL335981A patent/PL196830B1/pl unknown
-
2008
- 2008-09-04 JP JP2008226898A patent/JP5290671B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1998043657A2 (de) | 1998-10-08 |
ES2264201T3 (es) | 2006-12-16 |
EP1009419A2 (de) | 2000-06-21 |
EP1009419B1 (de) | 2006-05-24 |
PL335981A1 (en) | 2000-06-05 |
JP2002511842A (ja) | 2002-04-16 |
US6919086B1 (en) | 2005-07-19 |
PL196830B1 (pl) | 2008-02-29 |
DE59813556D1 (de) | 2006-06-29 |
PT1009419E (pt) | 2006-10-31 |
JP5290671B2 (ja) | 2013-09-18 |
JP2009062368A (ja) | 2009-03-26 |
WO1998043657A3 (de) | 1999-01-21 |
JP4347418B2 (ja) | 2009-10-21 |
ATE327252T1 (de) | 2006-06-15 |
DE19713001A1 (de) | 1998-10-01 |
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