HU9901478A3 - Carboline derivatives, their use, production thereof and medicaments containing the same - Google Patents

Carboline derivatives, their use, production thereof and medicaments containing the same

Info

Publication number
HU9901478A3
HU9901478A3 HU9901478A HU9901478A HU9901478A3 HU 9901478 A3 HU9901478 A3 HU 9901478A3 HU 9901478 A HU9901478 A HU 9901478A HU 9901478 A HU9901478 A HU 9901478A HU 9901478 A3 HU9901478 A3 HU 9901478A3
Authority
HU
Hungary
Prior art keywords
production
same
use
medicaments containing
carboline derivatives
Prior art date
Application number
HU9901478A
Other versions
HU9901478A2 (en
Original Assignee
Icos Corp Bothell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GBGB9609777.9A priority Critical patent/GB9609777D0/en
Priority to GBGB9609820.7A priority patent/GB9609820D0/en
Application filed by Icos Corp Bothell filed Critical Icos Corp Bothell
Publication of HU9901478A2 publication Critical patent/HU9901478A2/en
Publication of HU9901478A3 publication Critical patent/HU9901478A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
HU9901478A 1996-05-10 1997-05-05 Carboline derivatives, their use, production thereof and medicaments containing the same HU9901478A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB9609777.9A GB9609777D0 (en) 1996-05-10 1996-05-10 Chemical compounds
GBGB9609820.7A GB9609820D0 (en) 1996-05-10 1996-05-10 Chemical compounds

Publications (2)

Publication Number Publication Date
HU9901478A2 HU9901478A2 (en) 1999-08-30
HU9901478A3 true HU9901478A3 (en) 1999-11-29

Family

ID=26309303

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901478A HU9901478A3 (en) 1996-05-10 1997-05-05 Carboline derivatives, their use, production thereof and medicaments containing the same

Country Status (26)

Country Link
US (2) US6117881A (en)
EP (1) EP0912567B1 (en)
JP (1) JP3418405B2 (en)
KR (1) KR20000010918A (en)
CN (1) CN1067071C (en)
AP (1) AP9801365A0 (en)
AT (1) AT215950T (en)
AU (1) AU711885B2 (en)
BG (1) BG102879A (en)
BR (1) BR9709230A (en)
CA (1) CA2253948C (en)
CZ (1) CZ358598A3 (en)
DE (2) DE69711882T2 (en)
EA (1) EA199800907A1 (en)
EE (1) EE9800390A (en)
ES (1) ES2175404T3 (en)
HU (1) HU9901478A3 (en)
IL (1) IL126951D0 (en)
IS (1) IS4864A (en)
NO (1) NO985222L (en)
OA (1) OA10920A (en)
PL (1) PL329875A1 (en)
SK (1) SK154498A3 (en)
TR (1) TR199802282T2 (en)
WO (1) WO1997043287A1 (en)
YU (1) YU49898A (en)

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HU9901478A3 (en) * 1996-05-10 1999-11-29 Icos Corp Bothell Carboline derivatives, their use, production thereof and medicaments containing the same
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JP2004536816A (en) * 2001-06-05 2004-12-09 リリー アイコス リミテッド ライアビリティ カンパニー Pde5 carboline derivatives as inhibitors
AT335742T (en) * 2001-06-21 2006-09-15 Lilly Icos Llc Carbolic derivatives as PDEV inhibitors
MXPA04004370A (en) 2001-11-09 2004-08-11 Schering Corp Polycyclic guanine derivative phosphodiesterase v inhibitors.
EP1458679B1 (en) 2001-12-20 2010-01-20 Merck Serono SA Pyrrolidine derivatives as prostaglandin modulators
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
CA2529307C (en) 2003-06-13 2013-12-24 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP4671123B2 (en) 2003-06-23 2011-04-13 小野薬品工業株式会社 New tricyclic heterocyclic compounds
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US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
AU2005247746B2 (en) 2004-05-26 2010-11-11 Eisai R&D Management Co., Ltd. Cinnamide compound
SA2439B1 (en) 2004-05-26 2010-06-16 إيساي آر آند دي منجمنت كو.، ليمتد Cinnamide compound
ES2338904T3 (en) 2004-10-26 2010-05-13 EISAI R&D MANAGEMENT CO., LTD. Form amorfa of cinamide compounds.
ES2459742T3 (en) 2004-12-22 2014-05-12 Ono Pharmaceutical Co., Ltd. Tricyclic compound and use thereof
US8506934B2 (en) 2005-04-29 2013-08-13 Robert I. Henkin Methods for detection of biological substances
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009512711A (en) 2005-10-21 2009-03-26 ブレインセルス,インコーポレイティド Regulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
MX2008006076A (en) 2005-11-09 2008-12-16 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions.
EP1953151A4 (en) * 2005-11-18 2010-06-02 Eisai R&D Man Co Ltd Salts of cynnamide compound or solvates thereof
JPWO2007058305A1 (en) * 2005-11-18 2009-05-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 Method for producing cinnamide derivative
TWI370130B (en) 2005-11-24 2012-08-11 Eisai R&D Man Co Ltd Two cyclic cinnamide compound
US20070117839A1 (en) * 2005-11-24 2007-05-24 Eisai R&D Management Co., Ltd. Two cyclic cinnamide compound
JP5221144B2 (en) 2005-11-24 2013-06-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 Morpholine-type cinnamide compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
TWI378091B (en) 2006-03-09 2012-12-01 Eisai R&D Man Co Ltd Multi-cyclic cinnamide derivatives
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
US7737141B2 (en) 2006-07-28 2010-06-15 Eisai R&D Management Co., Ltd. Prodrug of cinnamide compound
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US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008095136A2 (en) 2007-01-31 2008-08-07 Henkin Robert I Methods for detection of biological substances
US20080207900A1 (en) * 2007-02-28 2008-08-28 Teiji Kimura Two cyclic oxomorphorin derivatives
WO2008140111A1 (en) * 2007-05-16 2008-11-20 Eisai R & D Management Co., Ltd. One-pot production process for cinnamide derivative
US7935815B2 (en) 2007-08-31 2011-05-03 Eisai R&D Management Co., Ltd. Imidazoyl pyridine compounds and salts thereof
CN101815713B (en) 2007-08-31 2013-09-11 卫材R&D管理有限公司 Polycyclic compound
EP2239265A1 (en) * 2008-01-28 2010-10-13 Eisai R&D Management Co., Ltd. Crystalline cinnamide compounds or salts thereof
US8580801B2 (en) 2008-07-23 2013-11-12 Robert I. Henkin Phosphodiesterase inhibitor treatment
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US20150297601A1 (en) 2012-10-05 2015-10-22 Robert I. Henkin Phosphodiesterase inhibitor treatment
EP3108245A4 (en) 2014-02-18 2017-11-01 Robert I. Henkin Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell

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HU9901478A3 (en) * 1996-05-10 1999-11-29 Icos Corp Bothell Carboline derivatives, their use, production thereof and medicaments containing the same
US5874437A (en) * 1996-11-01 1999-02-23 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses

Also Published As

Publication number Publication date
CA2253948A1 (en) 1997-11-20
CZ358598A3 (en) 1999-03-17
AU711885B2 (en) 1999-10-21
BG102879A (en) 1999-09-30
EP0912567A1 (en) 1999-05-06
AU2891097A (en) 1997-12-05
JP3418405B2 (en) 2003-06-23
DE69711882D1 (en) 2002-05-16
IL126951D0 (en) 1999-09-22
NO985222D0 (en) 1998-11-09
US6306870B1 (en) 2001-10-23
US6117881A (en) 2000-09-12
YU49898A (en) 2000-03-21
JP2000513717A (en) 2000-10-17
CA2253948C (en) 2005-07-26
KR20000010918A (en) 2000-02-25
CN1067071C (en) 2001-06-13
PL329875A1 (en) 1999-04-12
IS4864A (en) 1998-10-13
EP0912567B1 (en) 2002-04-10
HU9901478A2 (en) 1999-08-30
BR9709230A (en) 1999-08-10
EE9800390A (en) 1999-06-15
AT215950T (en) 2002-04-15
TR199802282T2 (en) 1999-03-22
ES2175404T3 (en) 2002-11-16
SK154498A3 (en) 2000-01-18
WO1997043287A1 (en) 1997-11-20
AP9801365A0 (en) 1998-12-31
OA10920A (en) 2003-02-21
CN1218471A (en) 1999-06-02
DE69711882T2 (en) 2002-10-31
EA199800907A1 (en) 1999-04-29
NO985222L (en) 1999-01-11

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