HU895572D0 - Fermentative process - Google Patents

Fermentative process

Info

Publication number
HU895572D0
HU895572D0 HU895572A HU557289A HU895572D0 HU 895572 D0 HU895572 D0 HU 895572D0 HU 895572 A HU895572 A HU 895572A HU 557289 A HU557289 A HU 557289A HU 895572 D0 HU895572 D0 HU 895572D0
Authority
HU
Hungary
Prior art keywords
fermentation
compounds
fermentative process
polyoxypropylene
yield
Prior art date
Application number
HU895572A
Other languages
Hungarian (hu)
Other versions
HU207350B (en
HUT56398A (en
Inventor
Maurice Peter Clarke
Hugh Stephen Collins
John David Mead
Original Assignee
Delta Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10643175&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU895572(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Publication of HU895572D0 publication Critical patent/HU895572D0/en
Publication of HUT56398A publication Critical patent/HUT56398A/en
Publication of HU207350B publication Critical patent/HU207350B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)

Abstract

The yield of secreted human serum albumin in a fermentation of genetically engineered yeast can be increased if a polyoxyalkylene compound is added, for example polypropylene glycol or polyoxypropylene/polyoxyethylene copolymers. Some of these compounds are routinely used in fermentation as antifoam compounds, but at lower levels.
HU895572A 1988-09-07 1989-09-06 Process for producing human serum albumine of greater quantity with fermentation HU207350B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888820951A GB8820951D0 (en) 1988-09-07 1988-09-07 Fermentation method

Publications (3)

Publication Number Publication Date
HU895572D0 true HU895572D0 (en) 1991-07-29
HUT56398A HUT56398A (en) 1991-08-28
HU207350B HU207350B (en) 1993-03-29

Family

ID=10643175

Family Applications (1)

Application Number Title Priority Date Filing Date
HU895572A HU207350B (en) 1988-09-07 1989-09-06 Process for producing human serum albumine of greater quantity with fermentation

Country Status (14)

Country Link
EP (1) EP0386222B1 (en)
JP (1) JP2996405B2 (en)
KR (1) KR900702001A (en)
AT (1) ATE118249T1 (en)
AU (1) AU618413B2 (en)
CA (1) CA1336416C (en)
DE (1) DE68921063T2 (en)
DK (1) DK107490A (en)
FI (1) FI96040C (en)
GB (1) GB8820951D0 (en)
HU (1) HU207350B (en)
IE (1) IE61268B1 (en)
WO (1) WO1990002808A2 (en)
ZA (1) ZA896847B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0404317A3 (en) * 1989-06-22 1991-10-02 Petrolite Corporation Use of ethoxylated propoxylated alcohols to prevent or reduce foam in fermentation broths
JPH0671432B2 (en) * 1991-03-20 1994-09-14 株式会社ミドリ十字 Method for producing human serum albumin
AU5413196A (en) * 1995-04-27 1996-11-18 Sucher & Holzer Bauplanungs- Und Handelsgesellschaft M.B.H. Worm press
PL335975A1 (en) * 1997-04-03 2000-06-05 Yoshitomi Pharmaceutical Method of obtaining a heterologous protein
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
DK2046826T3 (en) 2006-07-24 2011-10-24 Biorexis Pharmaceutical Corp Exendin-fusion proteins
JP7050528B2 (en) * 2017-03-01 2022-04-08 三洋化成工業株式会社 Production method of useful substances

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5338831B2 (en) * 1973-04-11 1978-10-18
DE2917535C2 (en) * 1979-04-30 1986-10-30 Hoechst Ag, 6230 Frankfurt Insulin solutions resistant to denaturation
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
EP0262516A2 (en) * 1986-09-29 1988-04-06 Miles Inc. Genetic transformation of lactic acid bacteria

Also Published As

Publication number Publication date
FI96040C (en) 1996-04-25
ATE118249T1 (en) 1995-02-15
DK107490D0 (en) 1990-05-01
EP0386222B1 (en) 1995-02-08
KR900702001A (en) 1990-12-05
JPH03500969A (en) 1991-03-07
HU207350B (en) 1993-03-29
ZA896847B (en) 1990-07-25
CA1336416C (en) 1995-07-25
DK107490A (en) 1990-05-01
FI902259A0 (en) 1990-05-04
IE61268B1 (en) 1994-10-19
AU618413B2 (en) 1991-12-19
AU4310789A (en) 1990-04-02
JP2996405B2 (en) 1999-12-27
EP0386222A1 (en) 1990-09-12
WO1990002808A3 (en) 1990-04-19
DE68921063T2 (en) 1995-07-06
HUT56398A (en) 1991-08-28
IE892864L (en) 1990-03-07
WO1990002808A2 (en) 1990-03-22
GB8820951D0 (en) 1988-10-05
DE68921063D1 (en) 1995-03-23
FI96040B (en) 1996-01-15

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees