HU0402140A3 - Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol - Google Patents

Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol

Info

Publication number
HU0402140A3
HU0402140A3 HU0402140A HU0402140A HU0402140A3 HU 0402140 A3 HU0402140 A3 HU 0402140A3 HU 0402140 A HU0402140 A HU 0402140A HU 0402140 A HU0402140 A HU 0402140A HU 0402140 A3 HU0402140 A3 HU 0402140A3
Authority
HU
Hungary
Prior art keywords
furo
hexahydro
furan
ol
preparation
Prior art date
Application number
HU0402140A
Other versions
HU229505B1 (en
HU0402140A2 (en
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to EP01203416 priority Critical
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Priority to PCT/EP2002/010062 priority patent/WO2003022853A1/en
Publication of HU0402140A2 publication Critical patent/HU0402140A2/en
Publication of HU0402140A3 publication Critical patent/HU0402140A3/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8180908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU0402140(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of HU229505B1 publication Critical patent/HU229505B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
HU0402140A 2001-09-10 2002-09-06 Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol HU229505B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01203416 2001-09-10
PCT/EP2002/010062 WO2003022853A1 (en) 2001-09-10 2002-09-06 Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol

Publications (3)

Publication Number Publication Date
HU0402140A2 HU0402140A2 (en) 2005-02-28
HU0402140A3 true HU0402140A3 (en) 2007-05-29
HU229505B1 HU229505B1 (en) 2014-01-28

Family

ID=8180908

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402140A HU229505B1 (en) 2001-09-10 2002-09-06 Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol

Country Status (28)

Country Link
US (1) US7126015B2 (en)
EP (1) EP1448567B1 (en)
JP (1) JP4521185B2 (en)
KR (1) KR100894673B1 (en)
CN (2) CN101172980B (en)
AP (1) AP1758A (en)
AR (1) AR036501A1 (en)
AT (1) AT453648T (en)
AU (1) AU2002333809C1 (en)
BR (2) BR0212341A (en)
CA (1) CA2459168C (en)
CY (1) CY1109974T1 (en)
DE (1) DE60234952D1 (en)
DK (1) DK1448567T3 (en)
EA (1) EA010883B1 (en)
ES (1) ES2338538T3 (en)
HK (1) HK1068887A1 (en)
HR (1) HRP20040320B1 (en)
HU (1) HU229505B1 (en)
IL (2) IL160166D0 (en)
MX (1) MXPA04002247A (en)
NO (1) NO328934B1 (en)
NZ (1) NZ531641A (en)
PL (1) PL224030B1 (en)
PT (1) PT1448567E (en)
SI (1) SI21463B (en)
WO (1) WO2003022853A1 (en)
ZA (1) ZA200401501B (en)

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DK1532127T3 (en) * 2002-06-27 2007-02-05 Smithkline Beecham Corp Preparation of stereoisomers of (3alfa, 3alfa / beta, 6alfa / beta) hexahydrofuro (2,3-b) furan-3-ol
WO2004060895A1 (en) * 2002-12-27 2004-07-22 Sumitomo Chemical Company, Limited Process for producing hexahydrofurofuranol derivative, intermediate thereof and process for producing the same
JP4818124B2 (en) 2003-12-23 2011-11-16 テイボテク・フアーマシユーチカルズ・リミテツド (3R, 3aS, 6aR) -Hexahydrofuro [2,3-b] furan-3-yl (1S, 1R) -3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino] -1-benzyl Process for producing 2-hydroxypropyl carbamate
TWI383975B (en) * 2004-03-31 2013-02-01 Tibotec Pharm Ltd Methods for the preparation of (3r,3as,6ar) hexahydro-furo[2,3-b]furan-3-ol
JP5549898B2 (en) * 2006-03-31 2014-07-16 独立行政法人産業技術総合研究所 Process for producing 5-hydroxymethyl-2-furfural
CN102432621B (en) * 2006-11-09 2016-02-17 爱尔兰詹森科学公司 Preparation hexahydrofuro [2,3-b] furan-3-ol
CN101024646B (en) * 2007-02-06 2010-07-14 启东东岳药业有限公司 Method for purifying methoxyfuran-furan-2-one
ES2360654T3 (en) 2007-04-27 2011-06-08 Tibotec Pharmaceuticals Methods for the preparation of N-isobutyl-N- (2-hydroxy-3-amino-4-phenylbutyl) -p-nitrobenzenesulfonylamide.
US8592487B2 (en) 2007-10-26 2013-11-26 Concert Pharmaceuticals, Inc. Deuterated darunavir
TWI482775B (en) 2008-09-01 2015-05-01 Tibotec Pharm Ltd Process for the preparation of (3r,3as,6ar)-hexahydrofuro2,3-bfuran-3-yl(1s,2r)-3-(4-aminophenyl)sulfonyl(isobutyl)amino-1-benzyl-2-hydroxypropylcarbamate
US20110257111A1 (en) * 2008-10-24 2011-10-20 Harbeson Scott L Hydroxyethlamino Sulfonamide Derivatives
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
JP2013509400A (en) 2009-10-30 2013-03-14 ルパン リミテッドLupin Limited A novel preparation method of darunavir and fine particle size darunavir ethanol adduct
ES2516916T3 (en) 2010-01-28 2014-10-31 Mapi Pharma Limited Procedure for the preparation of darunavir and darunavir intermediates
PL2643326T3 (en) 2010-11-23 2017-06-30 Mylan Laboratories, Limited Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro[2,3-b]furan-3-ol
US8802724B2 (en) 2010-11-30 2014-08-12 Purdue Research Foundation Processes and intermediates for preparing substituted hexahydrofuro [2,3-b] furans
JPWO2014024898A1 (en) * 2012-08-09 2016-07-25 住友化学株式会社 Method for producing hexahydrofurofuranol derivative
CN103864813B (en) * 2012-12-18 2017-02-22 上海迪赛诺化学制药有限公司 A synthetic hexahydro-furo [2,3-b] furan-3-ol and its enantiomer of
US20180370982A1 (en) * 2015-06-25 2018-12-27 Msm Laboratories Private Limited Process for the preparation of [(1s,2r)-3-[[(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3r,3as,6ar)hexahydro furo[2,3-b]furan-3-yl ester and its amorphous form
CN107043385B (en) * 2016-02-05 2019-07-09 成都博腾药业有限公司 A method of preparing darunavir intermediate
US10407438B2 (en) 2016-10-27 2019-09-10 Gilead Sciences, Inc. Crystalline forms of darunavir
CN106928248B (en) * 2017-02-04 2019-01-04 青岛科技大学 A kind of method preparing (3R, 3aS, 6aR) hexahydro furyl simultaneously [2,3-b] furan-3-ol

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CU35543A1 (en) * 1980-10-09 1983-05-05 Hoffmann La Roche prostaglandins
NZ224497A (en) * 1987-05-18 1990-04-26 Janssen Pharmaceutica Nv Pharmaceutical composition comprising flunarizine
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
DK0715618T3 (en) * 1993-08-24 1999-08-23 Searle & Co Hydroxyethylaminosulfonamider for use as inhibitors of retroviral proteases
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RU2089545C1 (en) * 1994-09-28 1997-09-10 Ярославский государственный технический университет Method of preparing 2-methyl-2-ethyl-1,3-dioxolan-4- ylmethyl methacrylate
DE19510566A1 (en) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepine, benzoxazepine and benzothiazepine N-acetic acid derivatives and process for their preparation and medicaments containing these compounds
DE19638020A1 (en) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Gastrointestinal blood flow promoting drugs
KR20040004416A (en) * 1997-01-30 2004-01-13 노파르티스 아게 Oil-Free Pharmaceutical Compositions Containing Cyclosporin A
PT2336134T (en) * 1998-06-23 2016-10-19 The Board Of Trustees Of The Univ Of Illionis Fitness assay and methods for reducing resistance of hiv to therapy
WO1999067254A2 (en) * 1998-06-23 1999-12-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Multi-drug resistant retroviral protease inhibitors and use thereof
KR100336090B1 (en) * 1998-06-27 2002-05-27 윤승원 Solid dispersed preparation of poorly water-soluble drug containing oil, fatty acid or mixture thereof
DE19906310A1 (en) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Use of 3-(1-(2-aralkyl-2-carboxyethyl)-1-cyclopentanecarboxamido)-2,3,4,5-tetrahydro-2-oxo-1H-benz(b)azepine-1-acetic acid derivatives for treating hypertension
DE19932555A1 (en) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Drugs with a protective effect against oxidative-toxic and in particular cardiotoxic substances
IL149005D0 (en) * 1999-10-06 2002-11-10 Us Gov Health & Human Serv Hexahydrofuro-2', 3-bifuran-3-yl-n-{3'(1, 3-benzodioxol-5-ylsulfonyl) (isobutyl) amino-1-benzyl-2-hydroxypropyl} carbamate as restroviral protease inhibitor

Also Published As

Publication number Publication date
ZA200401501B (en) 2005-07-27
HK1068887A1 (en) 2010-05-07
NO328934B1 (en) 2010-06-21
HU0402140A2 (en) 2005-02-28
BR0212341A (en) 2004-07-27
AU2002333809B2 (en) 2008-02-28
PT1448567E (en) 2010-03-12
KR20040029425A (en) 2004-04-06
AP200402981A0 (en) 2004-03-31
AU2002333809C1 (en) 2009-02-05
HU229505B1 (en) 2014-01-28
PL224030B1 (en) 2016-11-30
EA200400430A1 (en) 2004-08-26
CY1109974T1 (en) 2014-09-10
JP2005502707A (en) 2005-01-27
CA2459168C (en) 2014-01-28
AU2002333809B9 (en) 2008-06-26
KR100894673B1 (en) 2009-04-24
DK1448567T3 (en) 2010-04-26
CN101172980B (en) 2011-11-16
US7126015B2 (en) 2006-10-24
AT453648T (en) 2010-01-15
CN1553915A (en) 2004-12-08
PL367817A1 (en) 2005-03-07
MXPA04002247A (en) 2005-09-07
EA010883B1 (en) 2008-12-30
CN101172980A (en) 2008-05-07
NO20041434L (en) 2004-06-10
CA2459168A1 (en) 2003-03-20
SI21463B (en) 2011-08-31
JP4521185B2 (en) 2010-08-11
EP1448567A1 (en) 2004-08-25
SI21463A (en) 2004-10-31
AP1758A (en) 2007-07-30
US20040249175A1 (en) 2004-12-09
ES2338538T3 (en) 2010-05-10
DE60234952D1 (en) 2010-02-11
BRPI0212341B1 (en) 2019-04-02
IL160166D0 (en) 2004-07-25
NZ531641A (en) 2005-08-26
EP1448567B1 (en) 2009-12-30
IL160166A (en) 2012-05-31
WO2003022853A1 (en) 2003-03-20
AR036501A1 (en) 2004-09-15
HRP20040320A2 (en) 2005-04-30
HRP20040320B1 (en) 2012-11-30
AU2002333809B8 (en) 2008-07-03
CN100519561C (en) 2009-07-29

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: TIBOTEC PHARMACEUTICALS LTD., IE

Free format text: FORMER OWNER(S): TIBOTEC PHARMACEUTICALS LTD., IE

GB9A Succession in title

Owner name: JANSSEN SCIENCES IRELAND UC, IE

Free format text: FORMER OWNER(S): TIBOTEC PHARMACEUTICALS LTD., IE; TIBOTEC PHARMACEUTICALS LTD., IE