HU0001650A3 - Improved expression vectors - Google Patents

Improved expression vectors

Info

Publication number
HU0001650A3
HU0001650A3 HU0001650A HU0001650A HU0001650A3 HU 0001650 A3 HU0001650 A3 HU 0001650A3 HU 0001650 A HU0001650 A HU 0001650A HU 0001650 A HU0001650 A HU 0001650A HU 0001650 A3 HU0001650 A3 HU 0001650A3
Authority
HU
Hungary
Prior art keywords
expression vectors
improved expression
improved
vectors
Prior art date
Application number
HU0001650A
Other versions
HU0001650A2 (en
Original Assignee
Neose Technologies Inc Horsham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US2954596P priority Critical
Application filed by Neose Technologies Inc Horsham filed Critical Neose Technologies Inc Horsham
Priority to PCT/US1997/020528 priority patent/WO1998020111A1/en
Publication of HU0001650A2 publication Critical patent/HU0001650A2/en
Publication of HU0001650A3 publication Critical patent/HU0001650A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of products other than chlorine, adipic acid, caprolactam, or chlorodifluoromethane, e.g. bulk or fine chemicals or pharmaceuticals
    • Y02P20/58Recycling
    • Y02P20/582Recycling of unreacted starting or intermediate materials
HU0001650A 1996-11-08 1997-11-07 Improved expression vectors HU0001650A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US2954596P true 1996-11-08 1996-11-08
PCT/US1997/020528 WO1998020111A1 (en) 1996-11-08 1997-11-07 Improved expression vectors

Publications (2)

Publication Number Publication Date
HU0001650A2 HU0001650A2 (en) 2000-09-28
HU0001650A3 true HU0001650A3 (en) 2001-09-28

Family

ID=21849585

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001650A HU0001650A3 (en) 1996-11-08 1997-11-07 Improved expression vectors

Country Status (13)

Country Link
US (1) US6117651A (en)
EP (1) EP0946711B1 (en)
JP (1) JP2001503274A (en)
KR (1) KR20000068934A (en)
CN (1) CN1244214A (en)
AT (1) AT386126T (en)
AU (1) AU718382B2 (en)
CA (1) CA2271230A1 (en)
DE (1) DE69738514D1 (en)
HU (1) HU0001650A3 (en)
IL (1) IL129843D0 (en)
NZ (1) NZ335628A (en)
WO (1) WO1998020111A1 (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1360310A2 (en) * 2001-02-13 2003-11-12 University Of Florida A bi-directional dual promoter complex with enhanced promoter activity for transgene expression in eukaryotes
EP1476557B1 (en) * 2002-01-31 2016-01-20 Saint Louis University A rapid and sensitive assay for the detection and quantification of coregulators of nucleic acid binding factors
US7172865B2 (en) * 2001-08-13 2007-02-06 Saint Louis University Rapid and sensitive assay for the detection and quantification of coregulators of nucleic acid binding factors
AU2004236174B2 (en) 2001-10-10 2011-06-02 Novo Nordisk A/S Glycopegylation methods and proteins/peptides produced by the methods
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7157277B2 (en) 2001-11-28 2007-01-02 Neose Technologies, Inc. Factor VIII remodeling and glycoconjugation of Factor VIII
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US8791070B2 (en) 2003-04-09 2014-07-29 Novo Nordisk A/S Glycopegylated factor IX
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
DE60336555D1 (en) 2002-06-21 2011-05-12 Novo Nordisk Healthcare Ag Pegylated glycoforms of factor vii
WO2004005221A2 (en) * 2002-07-03 2004-01-15 Dow Global Technologies Inc Benzoate- and anthranilate-inducible promoters
AU2003256754A1 (en) 2002-07-23 2004-02-09 Governors Of The University Of Alberta Synthesis of glycoproteins using bacterial glycosyltransferases
ES2420581T3 (en) 2003-03-14 2013-08-26 Biogenerix Gmbh water soluble polymers branched and their conjugates
WO2004103275A2 (en) 2003-05-09 2004-12-02 Neose Technologies, Inc. Compositions and methods for the preparation of human growth hormone glycosylation mutants
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
EP1656453A2 (en) * 2003-08-22 2006-05-17 Nucleonics, Inc. Eukaryotic expression systems for expression of inhibitory rna in multiple intracellular compartments
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
EP1888098A2 (en) 2005-05-25 2008-02-20 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
US7956032B2 (en) 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
NZ556436A (en) 2005-01-10 2010-11-26 Biogenerix Ag Glycopegylated granulocyte colony stimulating factor
US20060040856A1 (en) 2003-12-03 2006-02-23 Neose Technologies, Inc. Glycopegylated factor IX
US20080015142A1 (en) * 2003-12-03 2008-01-17 Defrees Shawn Glycopegylated Follicle Stimulating Hormone
ES2560657T3 (en) 2004-01-08 2016-02-22 Ratiopharm Gmbh O-linked glycosylation of peptides G-CSF
WO2005067601A2 (en) * 2004-01-09 2005-07-28 Neose Technologies, Inc. Vectors for recombinant protein expression in e.coli
AU2005222782B2 (en) 2004-02-04 2010-06-17 Ratiopharm Gmbh Methods of refolding mammalian glycosyltransferases
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
AU2005287365B2 (en) * 2004-08-23 2011-02-10 Alnylam Pharmaceuticals, Inc. Multiple RNA polymerase III promoter expression constructs
WO2006031811A2 (en) 2004-09-10 2006-03-23 Neose Technologies, Inc. Glycopegylated interferon alpha
EP2586456B1 (en) 2004-10-29 2016-01-20 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (FGF)
EP1871795A4 (en) 2005-04-08 2010-03-31 Biogenerix Ag Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
JP5216580B2 (en) * 2005-05-25 2013-06-19 ノヴォ ノルディスク アー/エス Glycopegylated first ix factor
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US8198045B2 (en) 2006-04-19 2012-06-12 Biogenerix Ag Expression of O-glycosylated therapeutic proteins in prokaryotic microorganisms
US20080280818A1 (en) 2006-07-21 2008-11-13 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As Methods for the purification of polypeptide conjugates
US9050304B2 (en) 2007-04-03 2015-06-09 Ratiopharm Gmbh Methods of treatment using glycopegylated G-CSF
WO2008136790A1 (en) 2007-05-02 2008-11-13 Merial Limited Dna plasmids having improved expression and stability
ES2551123T3 (en) 2007-06-12 2015-11-16 Ratiopharm Gmbh Improved process for the production of nucleotide sugars
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
RU2573587C2 (en) 2008-02-27 2016-01-20 Ново Нордиск А/С Conjugated factor viii molecules
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US4673641A (en) * 1982-12-16 1987-06-16 Molecular Genetics Research And Development Limited Partnership Co-aggregate purification of proteins
US4710473A (en) * 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
US4738921A (en) * 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
US4795706A (en) * 1985-01-31 1989-01-03 Eli Lilly And Company Novel expression control sequences
US5304472A (en) * 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
US5342763A (en) * 1992-11-23 1994-08-30 Genentech, Inc. Method for producing polypeptide via bacterial fermentation
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them

Also Published As

Publication number Publication date
EP0946711A4 (en) 2004-10-27
US6117651A (en) 2000-09-12
EP0946711A1 (en) 1999-10-06
CN1244214A (en) 2000-02-09
AU5252498A (en) 1998-05-29
HU0001650A2 (en) 2000-09-28
IL129843D0 (en) 2000-02-29
WO1998020111A1 (en) 1998-05-14
JP2001503274A (en) 2001-03-13
DE69738514D1 (en) 2008-03-27
CA2271230A1 (en) 1998-05-14
KR20000068934A (en) 2000-11-25
AT386126T (en) 2008-03-15
AU718382B2 (en) 2000-04-13
EP0946711B1 (en) 2008-02-13
NZ335628A (en) 2000-10-27

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees