HRP20240550T1 - Farmaceutski sastav u obliku oralne suspenzije koji uključuje flavonoidnu frakciju koja sadrži diosmin i ksantan gumu - Google Patents
Farmaceutski sastav u obliku oralne suspenzije koji uključuje flavonoidnu frakciju koja sadrži diosmin i ksantan gumu Download PDFInfo
- Publication number
- HRP20240550T1 HRP20240550T1 HRP20240550TT HRP20240550T HRP20240550T1 HR P20240550 T1 HRP20240550 T1 HR P20240550T1 HR P20240550T T HRP20240550T T HR P20240550TT HR P20240550 T HRP20240550 T HR P20240550T HR P20240550 T1 HRP20240550 T1 HR P20240550T1
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical composition
- composition according
- xanthan gum
- diosmin
- flavonoid fraction
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 9
- 229930003935 flavonoid Natural products 0.000 title claims 4
- 150000002215 flavonoids Chemical class 0.000 title claims 4
- 235000017173 flavonoids Nutrition 0.000 title claims 4
- VUYDGVRIQRPHFX-UHFFFAOYSA-N hesperidin Natural products COc1cc(ccc1O)C2CC(=O)c3c(O)cc(OC4OC(COC5OC(O)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 VUYDGVRIQRPHFX-UHFFFAOYSA-N 0.000 title claims 4
- 229920001285 xanthan gum Polymers 0.000 title claims 4
- 229940082509 xanthan gum Drugs 0.000 title claims 4
- 235000010493 xanthan gum Nutrition 0.000 title claims 4
- 239000000230 xanthan gum Substances 0.000 title claims 4
- GZSOSUNBTXMUFQ-NJGQXECBSA-N 5,7,3'-Trihydroxy-4'-methoxyflavone 7-O-rutinoside Natural products O(C[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](Oc2cc(O)c3C(=O)C=C(c4cc(O)c(OC)cc4)Oc3c2)O1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](C)O1 GZSOSUNBTXMUFQ-NJGQXECBSA-N 0.000 title claims 3
- GZSOSUNBTXMUFQ-YFAPSIMESA-N diosmin Chemical compound C1=C(O)C(OC)=CC=C1C(OC1=C2)=CC(=O)C1=C(O)C=C2O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)O1 GZSOSUNBTXMUFQ-YFAPSIMESA-N 0.000 title claims 3
- 229960004352 diosmin Drugs 0.000 title claims 3
- IGBKNLGEMMEWKD-UHFFFAOYSA-N diosmin Natural products COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 IGBKNLGEMMEWKD-UHFFFAOYSA-N 0.000 title claims 3
- 229940100692 oral suspension Drugs 0.000 title claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 claims 1
- YFVGIJBUXMQFOF-PJOVQGMDSA-N 5-hydroxy-2-(4-methoxyphenyl)-7-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one Chemical compound C1=CC(OC)=CC=C1C(OC1=C2)=CC(=O)C1=C(O)C=C2O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)O1 YFVGIJBUXMQFOF-PJOVQGMDSA-N 0.000 claims 1
- QAGGICSUEVNSGH-UHFFFAOYSA-N Diosmetin Natural products C1=C(O)C(OC)=CC=C1C1=CC(=O)C2=CC=C(O)C=C2O1 QAGGICSUEVNSGH-UHFFFAOYSA-N 0.000 claims 1
- QUQPHWDTPGMPEX-UHFFFAOYSA-N Hesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(COC4C(C(O)C(O)C(C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-UHFFFAOYSA-N 0.000 claims 1
- FKIYLTVJPDLUDL-FLPYCHHVSA-N Isorhoifolin Natural products C[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)C=C(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O FKIYLTVJPDLUDL-FLPYCHHVSA-N 0.000 claims 1
- FKIYLTVJPDLUDL-SLNHTJRHSA-N Isorhoifolin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C=C3C(C(C=C(O3)C=3C=CC(O)=CC=3)=O)=C(O)C=2)O1 FKIYLTVJPDLUDL-SLNHTJRHSA-N 0.000 claims 1
- YFVGIJBUXMQFOF-SAXLCNSLSA-N Linarin Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H](Oc2cc(O)c3C(=O)C=C(c4ccc(OC)cc4)Oc3c2)O1)[C@H]1[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O1 YFVGIJBUXMQFOF-SAXLCNSLSA-N 0.000 claims 1
- QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 claims 1
- APSNPMVGBGZYAJ-GLOOOPAXSA-N clematine Natural products COc1cc(ccc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 APSNPMVGBGZYAJ-GLOOOPAXSA-N 0.000 claims 1
- MBNGWHIJMBWFHU-UHFFFAOYSA-N diosmetin Chemical compound C1=C(O)C(OC)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 MBNGWHIJMBWFHU-UHFFFAOYSA-N 0.000 claims 1
- 229960001876 diosmetin Drugs 0.000 claims 1
- 235000015428 diosmetin Nutrition 0.000 claims 1
- 230000035622 drinking Effects 0.000 claims 1
- 150000002214 flavonoid derivatives Chemical class 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- QUQPHWDTPGMPEX-QJBIFVCTSA-N hesperidin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]4[C@@H]([C@H](O)[C@@H](O)[C@H](C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-QJBIFVCTSA-N 0.000 claims 1
- 229940025878 hesperidin Drugs 0.000 claims 1
- ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 201000002282 venous insufficiency Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Claims (8)
1. Farmaceutski sastav u obliku oralne suspenzije za piće u vrećici, koji sadrži diosmin kao aktivni sastojak i opcionalno flavonoidne derivate i ksantan gumu kao pomoćnu tvar.
2. Farmaceutski sastav prema patentnom zahtjevu 1, naznačen time što je aktivni sastojak pročišćena i mikronizirana flavonoidna frakcija.
3. Farmaceutski sastav prema patentnom zahtjevu 2, naznačen time što flavonoidna frakcija sadrži diosmin, hesperidin, izorhoifolin, linarin i diosmetin.
4. Farmaceutski sastav prema patentnom zahtjevu 2, naznačen time što je količina flavonoidne frakcije između 7% m/m i 20% m/m.
5. Farmaceutski sastav prema patentnom zahtjevu 1, naznačen time što je koncentracija ksantanske gume 0,5% m/v.
6. Farmaceutski sastav prema patentnom zahtjevu 1, naznačen time što je količina ksantan gume između 0,30% m/m i 0,60% m/m.
7. Farmaceutski sastav prema patentnom zahtjevu 1, koji sadrži jednu ili više farmaceutski prihvatljivih pomoćnih tvari odabranih između zaslađivača, aroma, konzervansa ili sredstva za prilagođavanje pH.
8. Farmaceutski sastav prema bilo kojem od patentnih zahtjeva 1 do 7, za njegovu upotrebu u liječenju venske insuficijencije.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1203579A FR2999934B1 (fr) | 2012-12-21 | 2012-12-21 | Composition pharmaceutique sous la forme d'une suspension orale comprenant une fraction flavonoique et de la gomme xanthane |
EP19213282.7A EP3669879B1 (fr) | 2012-12-21 | 2013-12-20 | Composition pharmaceutique sous la forme d'une suspension orale comprenant une fraction flavonoïque comprenant de la diosmine et de la gomme xanthane |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20240550T1 true HRP20240550T1 (hr) | 2024-07-19 |
Family
ID=47754590
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20240550TT HRP20240550T1 (hr) | 2012-12-21 | 2013-12-20 | Farmaceutski sastav u obliku oralne suspenzije koji uključuje flavonoidnu frakciju koja sadrži diosmin i ksantan gumu |
HRP20200829TT HRP20200829T1 (hr) | 2012-12-21 | 2020-05-21 | Farmaceutski pripravak u obliku oralne suspenzije koja uključuje flavonoidnu frakciju i ksantansku gumu |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20200829TT HRP20200829T1 (hr) | 2012-12-21 | 2020-05-21 | Farmaceutski pripravak u obliku oralne suspenzije koja uključuje flavonoidnu frakciju i ksantansku gumu |
Country Status (42)
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101725461B1 (ko) * | 2015-12-29 | 2017-04-10 | 연세대학교 산학협력단 | 디오스민을 유효성분으로 포함하는 탈모 예방 또는 치료용, 또는 발모 또는 육모 촉진용 조성물 |
RU2704976C2 (ru) * | 2017-05-10 | 2019-11-01 | Общество с ограниченной ответственностью "Трейдсервис" | Флеботропная комбинированная фармацевтическая композиция |
FR3083980B1 (fr) * | 2018-07-20 | 2021-04-16 | Servier Lab | Composition pharmaceutique sous la forme d'un comprime a croquer de diosmine ou d'une fraction flavonoique |
WO2021123341A1 (en) | 2019-12-20 | 2021-06-24 | Krka, D.D., Novo Mesto | Composition comprising diosmin |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR6967M (hr) * | 1968-01-22 | 1969-05-19 | ||
FR2661610B1 (fr) * | 1990-05-02 | 1994-09-30 | Rhone Poulenc Sante | Nouvelle forme lyophilisee de la diosmine et sa preparation. |
JPH0724560B2 (ja) | 1990-06-01 | 1995-03-22 | 株式会社ヤクルト本社 | 植物体エキス含有飲料 |
FR2668705A1 (fr) * | 1990-11-06 | 1992-05-07 | Bouchara Sa | Nouvelles preparations dermiques a action phlebotonique et leur procede de preparation. |
FR2726469B1 (fr) * | 1994-11-08 | 1996-12-13 | Adir | Composition pharmaceutique pour l'administration orale de flavonoides |
FR2748025B1 (fr) * | 1996-04-25 | 1998-10-30 | Adir | Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant |
JP4202439B2 (ja) * | 1996-10-01 | 2008-12-24 | 江崎グリコ株式会社 | フラボノイド可溶化法、その糖転移法及び高濃度フラボノイド溶液 |
AU730391B2 (en) * | 1996-10-10 | 2001-03-08 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
FR2781156B1 (fr) * | 1998-07-20 | 2001-06-29 | Lafon Labor | Composition pharmaceutique destinee notamment a la prevention et au traitement des radiomucites et des chimiomucites |
US20040161435A1 (en) * | 2003-02-14 | 2004-08-19 | Gupta Shyam K. | Skin Firming Anti-Aging Cosmetic Mask Compositions |
US20040219124A1 (en) * | 2003-05-01 | 2004-11-04 | Gupta Shyam K. | Cosmetic and Pharmaceutical Masks Based on Ion-Pair Delivery System |
US20080069779A1 (en) * | 2003-08-04 | 2008-03-20 | Foamix Ltd. | Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof |
US20070166255A1 (en) * | 2004-11-22 | 2007-07-19 | Gupta Shyam K | Treatment of Topical Discomforts Including Acne, Sunburn, Diaper Rash, Wound, Wrinkles and Dandruff/Hair Loss by Natural Lignans via Fatty Acid Desaturase Inhibition |
ITMI20050517A1 (it) * | 2005-03-30 | 2006-09-30 | Therapicon Srl | Composizione farmaceutica di una tipica frazione microcristallina di flavonoidi |
CN100444847C (zh) * | 2006-01-11 | 2008-12-24 | 刘展欣 | 一种微粒化地奥司明和橙皮甙组合物栓剂 |
DE102006020382A1 (de) * | 2006-04-28 | 2007-10-31 | Henkel Kgaa | Schnell trocknende kosmetische Emulsionen zur Roll-on-Applikation |
KR20080030835A (ko) * | 2006-10-02 | 2008-04-07 | 쎄라피콘 에스.알.엘. | 약학 조성물 |
US20080161248A1 (en) * | 2006-12-28 | 2008-07-03 | Wendye Robbins | Methods and Compositions for Therapeutic Treatment |
US8999395B2 (en) * | 2007-02-09 | 2015-04-07 | Ceva Sante Animale | Pharmaceutical compositions for oral administration in the form of stabilised aqueous suspensions |
WO2009083759A1 (en) * | 2008-01-03 | 2009-07-09 | Wockhardt Research Centre | Oral pharmaceutical suspension comprising paracetamol and ibuprofen |
EP2353596A1 (en) * | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency |
US20110223256A1 (en) * | 2010-03-11 | 2011-09-15 | Stokely-Van Camp, Inc. | Method For Stabilizing Flavonoid Aqueous Dispersion |
US20120070475A1 (en) * | 2010-03-11 | 2012-03-22 | Pepsico, Inc | Zero Calorie Polyphenol Aqueous Dispersions |
-
2012
- 2012-12-21 FR FR1203579A patent/FR2999934B1/fr active Active
-
2013
- 2013-12-02 PH PH12013000362A patent/PH12013000362B1/en unknown
- 2013-12-03 SG SG2013089255A patent/SG2013089255A/en unknown
- 2013-12-05 TN TNP2013000505A patent/TN2013000505A1/fr unknown
- 2013-12-05 PE PE2013002757A patent/PE20141302A1/es not_active Application Discontinuation
- 2013-12-06 CH CH02023/13A patent/CH707354B1/fr unknown
- 2013-12-09 MX MX2013014519A patent/MX355719B/es active IP Right Grant
- 2013-12-09 JO JOP/2013/0355A patent/JO3688B1/ar active
- 2013-12-09 SV SV2013004600A patent/SV2013004600A/es unknown
- 2013-12-12 CR CR20130652A patent/CR20130652A/es unknown
- 2013-12-12 UY UY0001035190A patent/UY35190A/es not_active Application Discontinuation
- 2013-12-13 CL CL2013003588A patent/CL2013003588A1/es unknown
- 2013-12-13 CO CO13291852A patent/CO6970124A1/es unknown
- 2013-12-17 MY MYPI2013702456A patent/MY160753A/en unknown
- 2013-12-17 AP AP2013007323A patent/AP2013007323A0/xx unknown
- 2013-12-17 RO ROA201301007A patent/RO130611A2/ro unknown
- 2013-12-17 BR BR102013032405-1A patent/BR102013032405A2/pt not_active Application Discontinuation
- 2013-12-18 MA MA36588A patent/MA35600B1/fr unknown
- 2013-12-18 CU CUP2013000166A patent/CU24209B1/es active IP Right Grant
- 2013-12-18 UA UAA201314859A patent/UA119025C2/uk unknown
- 2013-12-19 GT GT201300316A patent/GT201300316A/es unknown
- 2013-12-20 ES ES19213282T patent/ES2975236T3/es active Active
- 2013-12-20 NI NI201300144A patent/NI201300144A/es unknown
- 2013-12-20 PL PL13198744T patent/PL2745839T3/pl unknown
- 2013-12-20 WO PCT/FR2013/053231 patent/WO2014096740A1/fr active Application Filing
- 2013-12-20 EP EP19213282.7A patent/EP3669879B1/fr active Active
- 2013-12-20 SI SI201332078T patent/SI3669879T1/sl unknown
- 2013-12-20 LT LTEP13198744.8T patent/LT2745839T/lt unknown
- 2013-12-20 AR ARP130104961A patent/AR094224A1/es not_active Application Discontinuation
- 2013-12-20 SI SI201331727T patent/SI2745839T1/sl unknown
- 2013-12-20 PL PL19213282.7T patent/PL3669879T3/pl unknown
- 2013-12-20 PT PT192132827T patent/PT3669879T/pt unknown
- 2013-12-20 KR KR1020130160482A patent/KR101595107B1/ko active IP Right Grant
- 2013-12-20 CN CN201310711339.8A patent/CN103877108A/zh active Pending
- 2013-12-20 HU HUE19213282A patent/HUE066379T2/hu unknown
- 2013-12-20 DK DK19213282.7T patent/DK3669879T3/da active
- 2013-12-20 LT LTEP19213282.7T patent/LT3669879T/lt unknown
- 2013-12-20 EA EA201301300A patent/EA030949B1/ru unknown
- 2013-12-20 RU RU2013156775/15A patent/RU2582954C2/ru active
- 2013-12-20 HR HRP20240550TT patent/HRP20240550T1/hr unknown
- 2013-12-20 DK DK13198744.8T patent/DK2745839T3/da active
- 2013-12-20 CN CN201810253066.XA patent/CN108392468A/zh active Pending
- 2013-12-20 RS RS20200422A patent/RS60172B1/sr unknown
- 2013-12-20 RS RS20240401A patent/RS65369B1/sr unknown
- 2013-12-20 EP EP13198744.8A patent/EP2745839B1/fr active Active
- 2013-12-20 ES ES13198744T patent/ES2781755T3/es active Active
- 2013-12-20 ME MEP-2020-73A patent/ME03771B/me unknown
- 2013-12-20 PT PT131987448T patent/PT2745839T/pt unknown
- 2013-12-20 FI FIEP19213282.7T patent/FI3669879T3/fi active
- 2013-12-20 HU HUE13198744A patent/HUE048969T2/hu unknown
-
2014
- 2014-12-15 HK HK14112567.2A patent/HK1198934A1/xx unknown
- 2014-12-23 HK HK14112848.3A patent/HK1199216A1/xx unknown
-
2020
- 2020-05-21 HR HRP20200829TT patent/HRP20200829T1/hr unknown
- 2020-06-04 CY CY20201100502T patent/CY1123021T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20200829T1 (hr) | Farmaceutski pripravak u obliku oralne suspenzije koja uključuje flavonoidnu frakciju i ksantansku gumu | |
HRP20200434T1 (hr) | Stabilne vodene formulacije adalimumaba | |
HRP20160605T1 (hr) | Tetraciklički spoj | |
WO2012143576A3 (en) | Compounds for preventing, reducing and/or alleviating itchy skin condition(s) | |
MX2010003923A (es) | Formulacion farmaceutica de valsartan. | |
UA105766C2 (uk) | Фармацевтична композиція, яка містить сіль стронцію, вітамін d і циклодекстрин | |
UA106636C2 (uk) | Морфолінотіазоли як позитивні алостеричні модулятори альфа 7 | |
UA102254C2 (ru) | Жидкий состав для деферипрона с приятным вкусом | |
EP2796450A4 (en) | 6-AMINOPYRIDINE-3-OL DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, AND PHARMACEUTICAL COMPOSITION CONTAINING THESE DERIVATIVES OR THESE SALTS AS ACTIVE INGREDIENTS FOR THE PREVENTION OR TREATMENT OF ANGIOGENESIS DISEASES | |
JP2014530801A5 (hr) | ||
PT2459153E (pt) | Composição farmacêutica ou cosmética ou dietética tendo o efeito de favorecer a pigmentação capilar | |
MX2010005198A (es) | Composiciones liquidas que comprenden valsartan. | |
BRPI0922870A8 (pt) | uso de ao menos um composto da fórmula i, do composto ohod ou seus derivados farmaceuticamente aceitáveis, do composto na-ohod, composição farmacêutica e/ou nutracêutica e método cosmético | |
RS54632B1 (en) | LIQUID PHARMACEUTICAL COMPOSITION CONTAINING NITIZINON | |
WO2012161497A3 (ko) | 보습능이 우수한 펩타이드 유도체 및 이의 용도 | |
WO2013012835A3 (en) | Sirna useful in the treatment of flavivirus infection | |
EA201892842A1 (ru) | Фармацевтические композиции, включающие сафинамид | |
EA201200754A1 (ru) | Традиционное китайское лекарственное средство, содержащее экстракты дан-шен (danshen) и сан-ки (sanqi), и его применение | |
EA201270411A1 (ru) | Синтетический гибрид гидротальцит-эудрагида урсодеоксихолевой кислоты, содержащая его фармацевтическая композиция и способ их получения | |
CO6460763A2 (es) | Métodos y formulaciones ectoparasiticidas | |
BR112013027685A2 (pt) | composição oral líquida compreendendo divalproex sódico e processo de preparação do mesmo | |
EA201500446A1 (ru) | Фармацевтическая композиция для снижения уровня n-оксида триметиламина | |
WO2011161223A3 (en) | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts | |
WO2011013086A3 (en) | Pharmaceutical, cosmetic or dietetic composition for skin bleaching | |
HRP20210266T1 (hr) | Pripravak prikladan za očuvanje fiziološkog stanja kože i kose i ponovnu uspostavu njihovih regenerativnih funkcija |