HRP20171848T1 - Upotreba malononitrilamida za neuropatsku bol - Google Patents

Upotreba malononitrilamida za neuropatsku bol

Info

Publication number
HRP20171848T1
HRP20171848T1 HRP20171848TT HRP20171848T HRP20171848T1 HR P20171848 T1 HRP20171848 T1 HR P20171848T1 HR P20171848T T HRP20171848T T HR P20171848TT HR P20171848 T HRP20171848 T HR P20171848T HR P20171848 T1 HRP20171848 T1 HR P20171848T1
Authority
HR
Croatia
Prior art keywords
malononitrilamides
neuropathic pain
neuropathic
pain
Prior art date
Application number
HRP20171848TT
Other languages
English (en)
Inventor
Birgit Hasse
Guido Koopmans
Original Assignee
Algiax Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US40819510P priority Critical
Priority to EP10014122 priority
Priority to PCT/EP2011/005452 priority patent/WO2012055567A2/en
Priority to EP11784418.3A priority patent/EP2632451B1/en
Application filed by Algiax Pharmaceuticals Gmbh filed Critical Algiax Pharmaceuticals Gmbh
Publication of HRP20171848T1 publication Critical patent/HRP20171848T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
HRP20171848TT 2010-10-29 2017-11-28 Upotreba malononitrilamida za neuropatsku bol HRP20171848T1 (hr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US40819510P true 2010-10-29 2010-10-29
EP10014122 2010-10-29
PCT/EP2011/005452 WO2012055567A2 (en) 2010-10-29 2011-10-28 Use of malononitrilamides in neuropathic pain
EP11784418.3A EP2632451B1 (en) 2010-10-29 2011-10-28 Use of malononitrilamides in neuropathic pain

Publications (1)

Publication Number Publication Date
HRP20171848T1 true HRP20171848T1 (hr) 2018-02-09

Family

ID=44992853

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171848TT HRP20171848T1 (hr) 2010-10-29 2017-11-28 Upotreba malononitrilamida za neuropatsku bol

Country Status (16)

Country Link
US (2) US20130217737A1 (hr)
EP (1) EP2632451B1 (hr)
JP (1) JP6257326B2 (hr)
CN (1) CN103179962B (hr)
CA (1) CA2814371C (hr)
DK (1) DK2632451T3 (hr)
ES (1) ES2655084T3 (hr)
HR (1) HRP20171848T1 (hr)
HU (1) HUE034890T2 (hr)
LT (1) LT2632451T (hr)
NO (1) NO2632451T3 (hr)
PL (1) PL2632451T3 (hr)
PT (1) PT2632451T (hr)
RS (1) RS56713B1 (hr)
SI (1) SI2632451T1 (hr)
WO (1) WO2012055567A2 (hr)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013168023A1 (en) 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for treatment of parkinson's disease
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
JP2015519333A (ja) 2012-05-07 2015-07-09 セリックスビオ プライヴェート リミテッド 神経疾患の治療のための組成物および方法
AU2013257742A1 (en) 2012-05-07 2014-11-27 Cellixbio Private Limited Compositions and methods for treatment of neuromuscular disorders and neurodegenerative disorders
WO2013167990A1 (en) 2012-05-07 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of depression
WO2013167991A1 (en) 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic disorders
US9403826B2 (en) 2012-05-08 2016-08-02 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory disorders
WO2013168025A1 (en) 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for treatment of blood clotting disorders
US9434704B2 (en) 2012-05-08 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of neurological degenerative disorders
US9499527B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of familial amyloid polyneuropathy
WO2013168005A2 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
WO2013168001A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
US9315461B2 (en) 2012-05-10 2016-04-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurologic diseases
WO2013168000A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of severe pain
WO2013168004A2 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of fibromyalgia pain
WO2013167997A2 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome
WO2013168002A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of neurological conditions
WO2013168011A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of chronic pain
WO2013168015A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of asthma and allergy
WO2013168033A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for treatment of neurologic diseases
WO2013168016A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome
US9242939B2 (en) 2012-05-10 2016-01-26 Cellix Bio Private Limited Compositions and methods for the treatment of respiratory disorders
CN104603100A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗炎症性肠病的组合物和方法
US9765020B2 (en) 2012-05-23 2017-09-19 Cellix Bio Private Limited Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis
WO2013175344A2 (en) * 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
US9492409B2 (en) 2012-05-23 2016-11-15 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
CA2873098A1 (en) 2012-05-23 2013-11-28 Cellixbio Private Limited Compositions and methods for the treatment of multiple sclerosis
WO2013175347A2 (en) 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of respiratory disorders
WO2014020480A2 (en) 2012-08-03 2014-02-06 Mahesh Kandula Compositions and methods for the treatment migraine and neurologic diseases
WO2014037833A2 (en) 2012-09-06 2014-03-13 Mahesh Kandula Compositions and methods for the treatment inflammation and lipid disorders
AU2013311349A1 (en) 2012-09-08 2014-11-27 Cellixbio Private Limited Compositions and methods for treatment of inflammation and lipid disorders
AU2014276346A1 (en) 2013-06-04 2015-12-24 Cellixbio Private Limited Compositions and methods for the treatment of diabetes and pre-diabetes
NZ736131A (en) 2014-09-26 2019-04-26 Cellix Bio Private Ltd Compositions and methods for the treatment of epilepsy and neurological disorders
CN107207403A (zh) 2014-09-29 2017-09-26 塞尔利克斯生物私人有限公司 用于治疗多发性硬化的组合物和方法
SG11201703369WA (en) 2014-10-27 2017-05-30 Cellix Bio Private Ltd Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9173877B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US9150557B1 (en) 2014-11-05 2015-10-06 Cellix Bio Private Limited Compositions and methods for the treatment of hyperglycemia
US20160120838A1 (en) 2014-11-05 2016-05-05 Mahesh Kandula Compositions and methods for the treatment of inflammatory bowel disease
US9284287B1 (en) 2014-11-05 2016-03-15 Cellix Bio Private Limited Compositions and methods for the suppression of carbonic anhydrase activity
US10208014B2 (en) 2014-11-05 2019-02-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
EP3242869A1 (en) 2015-01-06 2017-11-15 Cellixbio Private Limited Compositions and methods for the treatment of inflammation and pain

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
JP2995086B2 (ja) 1990-05-18 1999-12-27 ヘキスト・アクチエンゲゼルシヤフト イソオキサゾール−4−カルボキサミド類およびヒドロキシアルキリデンシアノアセトアミド類を含有する製剤
GB9200275D0 (en) 1992-01-08 1992-02-26 Roussel Lab Ltd Chemical compounds
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
FR2727628B1 (fr) * 1994-12-02 1997-01-10 Roussel Uclaf Application des derives de 3-cycloalkyl-propanamide a titre de medicaments analgesiques
US6566395B1 (en) * 1999-05-25 2003-05-20 Biomedicines, Inc. Methods of treating proliferative disorders
GB0123571D0 (en) * 2001-04-05 2001-11-21 Aventis Pharm Prod Inc Use of (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide for treating multiple sclerosis
ES2591355T3 (es) * 2010-08-24 2016-11-28 Algiax Pharmaceuticals Gmbh Uso novedoso de leflunomida y malononitrilamidas

Also Published As

Publication number Publication date
SI2632451T1 (en) 2018-02-28
US20130217737A1 (en) 2013-08-22
EP2632451A2 (en) 2013-09-04
US20140357722A1 (en) 2014-12-04
LT2632451T (lt) 2018-02-12
HUE034890T2 (hu) 2018-03-28
DK2632451T3 (en) 2017-12-18
RS56713B1 (sr) 2018-03-30
CN103179962A (zh) 2013-06-26
CA2814371C (en) 2019-03-19
JP2013545730A (ja) 2013-12-26
CN103179962B (zh) 2017-03-22
WO2012055567A2 (en) 2012-05-03
NO2632451T3 (hr) 2018-03-17
PT2632451T (pt) 2017-12-14
ES2655084T3 (es) 2018-02-16
US9468615B2 (en) 2016-10-18
JP6257326B2 (ja) 2018-01-10
CA2814371A1 (en) 2012-05-03
EP2632451B1 (en) 2017-10-18
WO2012055567A3 (en) 2012-07-05
PL2632451T3 (pl) 2018-04-30

Similar Documents

Publication Publication Date Title
HRP20161748T1 (hr) Inhibitori lizinspecifične demetilaze-1 i njihove uporabe
IL249669A (en) Substituted 5-fluoro-1h-pyrazolopyridines and use thereof
HRP20171189T1 (hr) Bisaril-vezani ariltriazoloni i njihova uporaba
HK1206004A1 (en) Ingenol-3-acylates iii and ingenol-3-carbamates -3- iii -3-
IL247595D0 (en) Novel modulators and methods of use
ZA201302979B (en) Dianosis and treatment relating to th2 inhibition
HK1192879A1 (zh) 取代的 -苄基環烷基羧酸及其用途
ZA201304280B (en) Treatment of jak2-mediated conditions
IL220939D0 (en) Compounds and methods
EP2661264A4 (en) Melanin modification compositions and methods of use
EP2629736A4 (en) Tissue treatment
EP2606031A4 (en) Autotaxin inhibitors and uses thereof
EP2529658A4 (en) Medical device
EP2571435A4 (en) Bone anchors
HK1178149A1 (zh) 吡唑- -基-雜環基-甲酰胺化合物及其使用方法
EP2646468A4 (en) Anti-ngf compositions and use thereof
EP2377457A4 (en) Medical device
EP2620138A4 (en) Foam-type external skin preparation
EP2629782A4 (en) Use of exosomes to promote or enhance hair growth
GB201012175D0 (en) Procedure and mechanisms
EP2523664A4 (en) Compounds and methods
EP2565069A4 (en) Cooling-wind introduction structure
EP2542086A4 (en) Compounds and therapeutic uses thereof
GB201213868D0 (en) Improvements in or relating to methods of manufacture
EP2580985A4 (en) Head-hair treatment-agent applicator