HRP20050681A2 - Triazole compounds useful in therapy - Google Patents
Triazole compounds useful in therapy Download PDFInfo
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- HRP20050681A2 HRP20050681A2 HR20050681A HRP20050681A HRP20050681A2 HR P20050681 A2 HRP20050681 A2 HR P20050681A2 HR 20050681 A HR20050681 A HR 20050681A HR P20050681 A HRP20050681 A HR P20050681A HR P20050681 A2 HRP20050681 A2 HR P20050681A2
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- -1 Triazole compounds Chemical class 0.000 title claims description 80
- 238000002560 therapeutic procedure Methods 0.000 title description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 32
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- 229910052736 halogen Inorganic materials 0.000 claims description 30
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- 238000006243 chemical reaction Methods 0.000 claims description 20
- 229940079593 drug Drugs 0.000 claims description 18
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 17
- 208000019901 Anxiety disease Diseases 0.000 claims description 16
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- 125000000623 heterocyclic group Chemical group 0.000 claims description 14
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- QRPFSJHKCKQMFH-UHFFFAOYSA-N 1-[8-chloro-1-(1-pyridin-2-ylpiperidin-4-yl)-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-5-yl]ethanone;dihydrochloride Chemical compound Cl.Cl.N12C3=CC=C(Cl)C=C3CN(C(=O)C)CC2=NN=C1C(CC1)CCN1C1=CC=CC=N1 QRPFSJHKCKQMFH-UHFFFAOYSA-N 0.000 claims description 3
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- OHQOFXMSTWIWNX-UHFFFAOYSA-N 8-chloro-5-methyl-1-(1-pyrimidin-2-ylpiperidin-4-yl)-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine Chemical compound N12C3=CC=C(Cl)C=C3CN(C)CC2=NN=C1C(CC1)CCN1C1=NC=CC=N1 OHQOFXMSTWIWNX-UHFFFAOYSA-N 0.000 claims description 3
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Landscapes
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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GBGB0303852.8A GB0303852D0 (en) | 2003-02-19 | 2003-02-19 | Triazole compounds useful in therapy |
GBGB0317227.7A GB0317227D0 (en) | 2003-07-23 | 2003-07-23 | Treatment of male sexual dysfunction |
PCT/IB2004/000432 WO2004074291A1 (en) | 2003-02-19 | 2004-02-09 | Triazole compounds useful in therapy |
Publications (1)
Publication Number | Publication Date |
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HRP20050681A2 true HRP20050681A2 (en) | 2005-12-31 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HR20050681A HRP20050681A2 (en) | 2003-02-19 | 2005-07-29 | Triazole compounds useful in therapy |
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Country | Link |
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EP (1) | EP1597260B1 (ja) |
JP (2) | JP4033886B2 (ja) |
KR (1) | KR100750028B1 (ja) |
AP (1) | AP2005003376A0 (ja) |
AT (1) | ATE349449T1 (ja) |
AU (1) | AU2004213242B2 (ja) |
BR (1) | BRPI0407676A (ja) |
CA (1) | CA2516557C (ja) |
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ES (1) | ES2277237T3 (ja) |
GE (1) | GEP20074089B (ja) |
HR (1) | HRP20050681A2 (ja) |
IS (1) | IS2450B (ja) |
MA (1) | MA27712A1 (ja) |
MX (1) | MXPA05008923A (ja) |
NO (1) | NO20054053L (ja) |
OA (1) | OA13029A (ja) |
PL (1) | PL378747A1 (ja) |
PT (1) | PT1597260E (ja) |
RS (1) | RS20050638A (ja) |
SI (1) | SI1597260T1 (ja) |
TN (1) | TNSN05200A1 (ja) |
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WO2008133288A1 (ja) * | 2007-04-25 | 2008-11-06 | Daiichi Sankyo Company, Limited | 三環性アリール化合物 |
US8765728B2 (en) * | 2009-11-16 | 2014-07-01 | Mellitech | [1,5]-diazocin derivatives |
US8420633B2 (en) * | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8461151B2 (en) * | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8481528B2 (en) * | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US9006450B2 (en) * | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
JP6454707B2 (ja) * | 2013-12-05 | 2019-01-16 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | trans−8−クロロ−5−メチル−1−[4−(ピリジン−2−イルオキシ)−シクロヘキシル]−5,6−ジヒドロ−4H−2,3,5,10b−テトラアザ−ベンゾ[e]アズレン及びその結晶形態の合成 |
HU231206B1 (hu) * | 2017-12-15 | 2021-10-28 | Richter Gedeon Nyrt. | Triazolobenzazepinek |
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GB8823475D0 (en) * | 1988-10-06 | 1988-11-16 | Merck Sharp & Dohme | Chemical compounds |
US5438035A (en) * | 1994-06-24 | 1995-08-01 | American Cyanamid Company | Methods for controlling undesirable plant species with benzodiazepine compounds |
US5753648A (en) * | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
CN1330653C (zh) * | 1996-11-01 | 2007-08-08 | 惠氏公司 | 5h-吡咯并[2,1-c][1,4]-苯并二氮杂䓬的3-甲酰胺衍生物 |
DK1147115T5 (da) * | 1999-01-19 | 2008-12-08 | Ortho Mcneil Pharm Inc | Tricycliske benzodiazepiner som vasopressinreceptorantagonister |
US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
GB0224919D0 (en) * | 2002-10-25 | 2002-12-04 | Pfizer Ltd | Triazole compounds useful in therapy |
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- 2004-02-09 RS RSP-2005/0638A patent/RS20050638A/sr unknown
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2005
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