HRP20030690A2 - Preparation of n-methylparoxetine and related intermediate compounds - Google Patents

Preparation of n-methylparoxetine and related intermediate compounds Download PDF

Info

Publication number
HRP20030690A2
HRP20030690A2 HR20030690A HRP20030690A HRP20030690A2 HR P20030690 A2 HRP20030690 A2 HR P20030690A2 HR 20030690 A HR20030690 A HR 20030690A HR P20030690 A HRP20030690 A HR P20030690A HR P20030690 A2 HRP20030690 A2 HR P20030690A2
Authority
HR
Croatia
Prior art keywords
group
organic solvent
sesamol
compound
utilization
Prior art date
Application number
HR20030690A
Other languages
English (en)
Croatian (hr)
Inventor
Finkelstein Nina
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of HRP20030690A2 publication Critical patent/HRP20030690A2/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HR20030690A 2001-02-05 2002-02-04 Preparation of n-methylparoxetine and related intermediate compounds HRP20030690A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26649801P 2001-02-05 2001-02-05
US27758701P 2001-03-21 2001-03-21
PCT/US2002/003223 WO2002062790A1 (en) 2001-02-05 2002-02-04 Preparation of n-methylparoxetine and related intermediate compounds

Publications (1)

Publication Number Publication Date
HRP20030690A2 true HRP20030690A2 (en) 2005-04-30

Family

ID=26951885

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030690A HRP20030690A2 (en) 2001-02-05 2002-02-04 Preparation of n-methylparoxetine and related intermediate compounds

Country Status (10)

Country Link
US (1) US6777554B2 (cs)
EP (1) EP1366041A4 (cs)
KR (1) KR20040014452A (cs)
CA (1) CA2437392A1 (cs)
CZ (1) CZ20032354A3 (cs)
HR (1) HRP20030690A2 (cs)
HU (1) HUP0303153A2 (cs)
IL (1) IL157243A0 (cs)
SK (1) SK10992003A3 (cs)
WO (1) WO2002062790A1 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002006275A1 (en) * 2000-07-17 2002-01-24 Smithkline Beecham P.L.C. Novel processes for the preparation of 4-phenylpiperidine derivatives
US20080029570A1 (en) * 2006-08-02 2008-02-07 Shelton Frederick E Pneumatically powered surgical cutting and fastening instrument with improved volume storage
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4585777A (en) 1984-02-07 1986-04-29 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
DE3680184D1 (de) 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
IE66332B1 (en) 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
GB8714707D0 (en) 1987-06-23 1987-07-29 Beecham Group Plc Chemical process
FR2634207B1 (fr) 1988-07-12 1990-09-07 Synthelabo Derives de ((piperidinyl-4)methyl) benzazepines, leur preparation et leur application en therapeutique
EP0351283A1 (fr) 1988-07-12 1990-01-17 Synthelabo Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique
FR2659323B1 (fr) 1990-03-07 1992-06-12 Synthelabo Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
US5258517A (en) 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine
US6004990A (en) 1994-06-03 1999-12-21 Zebra Pharmaceuticals Meta substituted arylalkylamines and therapeutic and diagnostic uses therefor
GB9526645D0 (en) 1995-12-28 1996-02-28 Chiroscience Ltd Stereoselective synthesis
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1384711A1 (en) 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Optical resolution of a piperidine derivative
HU221921B1 (hu) 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
GB9710004D0 (en) 1997-05-17 1997-07-09 Knoll Ag Chemical process
WO2002006275A1 (en) 2000-07-17 2002-01-24 Smithkline Beecham P.L.C. Novel processes for the preparation of 4-phenylpiperidine derivatives
IL159280A0 (en) * 2001-06-14 2004-06-01 Teva Pharma A process for preparing paroxetine hcl which limits formation of pink colored compounds
CN1336363A (zh) * 2001-07-25 2002-02-20 张元宾 乙酰磺胺酸钾的合成制备方法
PT1440067E (pt) 2001-10-22 2005-02-28 Synthon Bv Derivados n-formilo de paroxetina

Also Published As

Publication number Publication date
US6777554B2 (en) 2004-08-17
IL157243A0 (en) 2004-02-19
EP1366041A4 (en) 2004-12-22
US20020151567A1 (en) 2002-10-17
WO2002062790A1 (en) 2002-08-15
EP1366041A1 (en) 2003-12-03
SK10992003A3 (sk) 2004-03-02
CZ20032354A3 (cs) 2004-08-18
CA2437392A1 (en) 2002-08-15
HUP0303153A2 (hu) 2004-03-01
KR20040014452A (ko) 2004-02-14

Similar Documents

Publication Publication Date Title
CS227007B2 (en) Method of preparing carbazol-4-yl oxypropanolamine derivatives
EP0994872A1 (en) 4-phenylpiperidine compounds
JP2003517013A (ja) フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物
US4760182A (en) Process for preparing substituted phenol ethers via oxazolidine-structure intermediates
DE60316683T2 (de) Phenylcyclohexylpropanolaminderivate, deren herstellung und therapeutsche anwendung
EP0674514A1 (en) Use of aryloxyalkyl substituted cyclic amines as calcium channel antagonists and new phenyloxyalkyl piperidin derivatives
OA10518A (en) Pyrrolidinyl hydroxamic acid compounds and their production process
HRP20030690A2 (en) Preparation of n-methylparoxetine and related intermediate compounds
US5665736A (en) N-benzoylmethyl-piperidines
EP0111326A1 (en) Process for the manufacture of chiral azetidinones
FI80261C (fi) Foerfarande foer optisk upploesning av en blandning av enantiomerer av trans-3-/(4-metoxifenoxi)-metyl/-1-metyl-4- fenylpiperidin.
EP0930291B1 (en) Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers
EP0542671B1 (de) Substituierte Hydrochinonderivate als Zwischenprodukte von Benzofuranderivaten
EP1375474A2 (en) Intermediate for the preparation of carvedilol
WO2001004093A2 (en) Process for producing paroxetine derivatives by mitsunobu reaction
KR100503157B1 (ko) 벤젠설폰아미드 화합물, 이들의 제조 방법 및 이들을함유하는 약제 조성물
KR950002832B1 (ko) 페놀에테르의 제조 방법
PL206307B1 (pl) 2,2-podstawione 1,3-dioksolany, sposób ich wytwarzania, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie
JPH0797373A (ja) フェノールエーテルの製造のための環状中間体
EP0170583A1 (fr) Sels d'ammonium dérivés de hexahydrodibenzodioxane, leurs intermédiaires, leur préparation et leur application en thérapeutique
JPS6128660B2 (cs)
GB2187190A (en) Preparation of phenol ether derivatives
HU221922B1 (hu) Eljárás paroxetinsók, valamint azok hidrátjai előállítására
CS205086B2 (cs) Způsob výroby hydroxyderivátů aryloxy- a arylthioperhydroazaheterocyklů

Legal Events

Date Code Title Description
ODRP Renewal fee for the maintenance of a patent

Payment date: 20040126

Year of fee payment: 3

A1OB Publication of a patent application
OBST Application withdrawn