HK1207887A1 - Assays, methods and apparatus for assessing rna disruption rna - Google Patents

Assays, methods and apparatus for assessing rna disruption rna

Info

Publication number
HK1207887A1
HK1207887A1 HK15108548.3A HK15108548A HK1207887A1 HK 1207887 A1 HK1207887 A1 HK 1207887A1 HK 15108548 A HK15108548 A HK 15108548A HK 1207887 A1 HK1207887 A1 HK 1207887A1
Authority
HK
Hong Kong
Prior art keywords
rna
assays
methods
assessing
disruption
Prior art date
Application number
HK15108548.3A
Other languages
English (en)
Chinese (zh)
Inventor
Kenneth Pritzker
Amadeo Mark Parissenti
Laura Pritzker
Mu Zhu
Xiaohui Wang
Stacey Santi
Rashmi Narendrula
Baoqing Guo
Original Assignee
Rna Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rna Diagnostics Inc filed Critical Rna Diagnostics Inc
Publication of HK1207887A1 publication Critical patent/HK1207887A1/xx

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/142Toxicological screening, e.g. expression profiles which identify toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
HK15108548.3A 2012-04-24 2015-09-01 Assays, methods and apparatus for assessing rna disruption rna HK1207887A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261637676P 2012-04-24 2012-04-24
US201361806222P 2013-03-28 2013-03-28
PCT/CA2013/000408 WO2013159200A1 (en) 2012-04-24 2013-04-24 Assays, methods and apparatus for assessing rna disruption

Publications (1)

Publication Number Publication Date
HK1207887A1 true HK1207887A1 (en) 2016-02-12

Family

ID=49482066

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108548.3A HK1207887A1 (en) 2012-04-24 2015-09-01 Assays, methods and apparatus for assessing rna disruption rna

Country Status (10)

Country Link
US (2) US11031096B2 (xx)
EP (2) EP3907294A1 (xx)
JP (1) JP6279549B2 (xx)
CN (1) CN104640998B (xx)
AU (1) AU2013252445B2 (xx)
BR (1) BR112014026440A8 (xx)
CA (1) CA2871195C (xx)
HK (1) HK1207887A1 (xx)
SG (1) SG11201406865PA (xx)
WO (1) WO2013159200A1 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014026440A8 (pt) 2012-04-24 2018-01-16 Rna Diagnostics Inc análises, métodos e aparelhos para avaliação de disrupção de rna.
EP2925892B1 (en) * 2012-12-03 2019-02-06 RNA Diagnostics Inc. Methods for monitoring response to radiation therapies in cancer
WO2015048887A1 (en) * 2013-10-04 2015-04-09 Rna Diagnostics Inc. Rna disruption assay for predicting survival
WO2016069539A1 (en) * 2014-10-27 2016-05-06 Helix Nanotechnologies, Inc. Systems and methods of screening with a molecule recorder
US10855748B2 (en) * 2015-09-30 2020-12-01 IntegenX, Inc. Command center
EP3405896A4 (en) * 2016-01-22 2019-09-25 Otraces Inc. SYSTEMS AND METHODS FOR ENHANCING DIAGNOSIS OF DISEASE
US20200080965A1 (en) * 2017-03-10 2020-03-12 Shimadzu Corporation Electrophoretic analysis method, electrophoretic analysis device, and electrophoretic analysis program
CN108253894B (zh) * 2018-02-06 2020-08-18 中原内配集团股份有限公司 一种气缸套表面凸起结构的检测方法
JP7533245B2 (ja) * 2021-01-27 2024-08-14 株式会社島津製作所 マイクロチップ電気泳動装置

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251247B1 (en) 1998-04-01 2001-06-26 Hitachi Chemical Co., Ltd. Detection of degradation of RNA using microchannel electrophoresis
US6873915B2 (en) 2001-08-24 2005-03-29 Surromed, Inc. Peak selection in multidimensional data
US20030203408A1 (en) 2002-04-02 2003-10-30 Stephen Williams Computer-implemented method for identifying peaks in electropherogram data
WO2004003820A2 (en) * 2002-07-01 2004-01-08 Institut Pasteur System, method, device, and computer program product for extraction, gathering, manipulation, and analysis of peak data from an automated sequencer
DE60323267D1 (en) 2002-12-31 2008-10-09 Pfizer Prod Inc Rna-bioassay
ATE331044T1 (de) 2003-03-04 2006-07-15 Pamgene Bv Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren
DE10315581B4 (de) 2003-04-05 2007-06-28 Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto Verfahren zur Qualitätsbestimmung von RNA-Proben
US20060063170A1 (en) 2004-03-18 2006-03-23 Arcturus Bioscience, Inc. Determination of RNA quality
US8131473B1 (en) 2004-05-20 2012-03-06 Metabolon, Inc. Data analysis methods for locating entities of interest within large, multivariable datasets
EP1815014B1 (en) 2004-11-05 2012-03-21 Genomic Health, Inc. Molecular indicators of breast cancer prognosis and prediction of treatment response
EP1772522A1 (en) 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Control of preservation by biomarkers
WO2007053491A2 (en) 2005-10-28 2007-05-10 The Trustees Of Columbia University In The City Of New York Method and kit for evaluating rna quality
EP2198296B1 (en) 2007-09-05 2015-11-11 Laurentian University Method of using tumour rna integrity to measure response to chemotherapy in cancer patients
US9150909B2 (en) 2008-08-29 2015-10-06 Bio-Rad Laboratories, Inc. Determination of the integrity of RNA
US7888035B2 (en) 2008-10-30 2011-02-15 Caris Mpi, Inc. Methods for assessing RNA patterns
WO2013020201A1 (en) 2011-08-10 2013-02-14 Amadeo Mark Parissenti Diagnostic methods and kits for monitoring response to chemotherapy in ovarian cancer
BR112014026440A8 (pt) 2012-04-24 2018-01-16 Rna Diagnostics Inc análises, métodos e aparelhos para avaliação de disrupção de rna.
EP2925892B1 (en) 2012-12-03 2019-02-06 RNA Diagnostics Inc. Methods for monitoring response to radiation therapies in cancer

Also Published As

Publication number Publication date
JP2015519887A (ja) 2015-07-16
AU2013252445B2 (en) 2018-01-18
BR112014026440A8 (pt) 2018-01-16
CA2871195C (en) 2023-01-10
US20150154350A1 (en) 2015-06-04
AU2013252445A1 (en) 2014-12-04
EP3907294A1 (en) 2021-11-10
AU2013252445A8 (en) 2015-01-15
EP2841604A1 (en) 2015-03-04
EP2841604A4 (en) 2016-01-06
US11031096B2 (en) 2021-06-08
JP6279549B2 (ja) 2018-02-14
CN104640998B (zh) 2018-08-14
WO2013159200A1 (en) 2013-10-31
SG11201406865PA (en) 2014-11-27
US20220028489A1 (en) 2022-01-27
CA2871195A1 (en) 2013-10-31
BR112014026440A2 (pt) 2017-06-27
CN104640998A (zh) 2015-05-20

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