HK1195260A1 - Fc receptor binding proteins fc - Google Patents

Fc receptor binding proteins fc

Info

Publication number
HK1195260A1
HK1195260A1 HK14108820.3A HK14108820A HK1195260A1 HK 1195260 A1 HK1195260 A1 HK 1195260A1 HK 14108820 A HK14108820 A HK 14108820A HK 1195260 A1 HK1195260 A1 HK 1195260A1
Authority
HK
Hong Kong
Prior art keywords
binding proteins
receptor binding
receptor
proteins
binding
Prior art date
Application number
HK14108820.3A
Other languages
Chinese (zh)
Inventor
.塞克斯頓
.湯乎爾
.維斯瓦納坦
Original Assignee
戴埃克斯有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 戴埃克斯有限公司 filed Critical 戴埃克斯有限公司
Publication of HK1195260A1 publication Critical patent/HK1195260A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
HK14108820.3A 2011-06-02 2014-08-29 Fc receptor binding proteins fc HK1195260A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161492617P 2011-06-02 2011-06-02
US201161498266P 2011-06-17 2011-06-17
PCT/US2012/040409 WO2012167039A1 (en) 2011-06-02 2012-06-01 Fc RECEPTOR BINDING PROTEINS

Publications (1)

Publication Number Publication Date
HK1195260A1 true HK1195260A1 (en) 2014-11-07

Family

ID=47259886

Family Applications (2)

Application Number Title Priority Date Filing Date
HK14108820.3A HK1195260A1 (en) 2011-06-02 2014-08-29 Fc receptor binding proteins fc
HK16100888.7A HK1213905A1 (en) 2011-06-02 2014-10-08 Fc receptor binding proteins fc

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16100888.7A HK1213905A1 (en) 2011-06-02 2014-10-08 Fc receptor binding proteins fc

Country Status (14)

Country Link
US (5) US9359438B2 (en)
EP (2) EP2966089B1 (en)
JP (3) JP6104897B2 (en)
KR (1) KR102014554B1 (en)
CN (2) CN103619353B (en)
AU (2) AU2012262007B2 (en)
BR (1) BR112013030352B1 (en)
CA (1) CA2837527C (en)
ES (1) ES2748583T3 (en)
HK (2) HK1195260A1 (en)
IL (1) IL229618B (en)
MX (1) MX343659B (en)
SG (2) SG195025A1 (en)
WO (1) WO2012167039A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010011679A (en) * 2008-04-25 2011-05-23 Dyax Corp Antibodies against fcrn and use thereof.
MX343659B (en) 2011-06-02 2016-11-16 Dyax Corp Fc RECEPTOR BINDING PROTEINS.
GB201208370D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Antibodies
GB201320066D0 (en) 2013-11-13 2013-12-25 Ucb Pharma Sa Biological products
CA2966352A1 (en) * 2013-11-26 2015-06-04 The Brigham And Women's Hospital, Inc. Compositions and methods for modulating an immune response
US10336825B2 (en) 2014-04-30 2019-07-02 Hanall Biopharma Co., Ltd. Antibody binding to FcRn for treating autoimmune diseases
EP3137504B1 (en) 2014-04-30 2023-05-10 Hanall Biopharma Co., Ltd. Antibody binding to fcrn for treating autoimmune diseases
KR20230007545A (en) * 2015-01-30 2023-01-12 모멘타 파머슈티컬스 인코포레이티드 FcRn Antibodies and Methods of Use thereof
EP3448429B1 (en) 2016-04-25 2021-01-13 Syntimmune Inc. Humanized affinity matured anti-fcrn antibodies
SI3491025T1 (en) * 2016-07-29 2024-02-29 Momenta Pharmaceuticals, Inc., Fcrn antibodies and methods of use thereof
EP3548320B1 (en) 2016-12-01 2022-12-07 SABIC Global Technologies B.V. Hybrid composite tailgate
SG11202005021PA (en) * 2017-12-13 2020-07-29 Momenta Pharmaceuticals Inc Fcrn antibodies and methods of use thereof
SG11202100419UA (en) * 2018-07-20 2021-02-25 Momenta Pharmaceuticals Inc Fcrn antibody compositions
CN114867745B (en) * 2019-07-23 2024-01-12 上海科技大学 ASIC1 channel antagonist antibodies
AU2021292200A1 (en) 2020-06-17 2023-02-02 The Trustees Of The University Of Pennsylvania Compositions and methods for treatment of gene therapy patients
US11926669B2 (en) 2022-05-30 2024-03-12 Hanall Biopharma Co., Ltd. Anti-FcRn antibody or antigen binding fragment thereof with improved stability

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
US4289747A (en) 1978-12-26 1981-09-15 E-Y Laboratories, Inc. Immunological determination using lectin
DE2901218A1 (en) 1979-01-13 1980-07-17 Byk Gulden Lomberg Chem Fab THEOPHYLLIN
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
MX9203291A (en) 1985-06-26 1992-08-01 Liposome Co Inc LIPOSOMAS COUPLING METHOD.
US4868103A (en) 1986-02-19 1989-09-19 Enzo Biochem, Inc. Analyte detection by means of energy transfer
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
ATE81724T1 (en) 1987-11-09 1992-11-15 Becton Dickinson Co PROCEDURE FOR ANALYZING HAEMATOPOIETIC CELLS IN A SAMPLE.
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1892296A1 (en) 1988-09-02 2008-02-27 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5030002A (en) 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
AU665190B2 (en) 1990-07-10 1995-12-21 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
IE76732B1 (en) 1990-08-07 1997-11-05 Becton Dickinson Co One step test for absolute counts
US5179107A (en) 1990-09-07 1993-01-12 Schering Corporation Antiviral quinolinone compounds
WO1992009690A2 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with altered binding properties
US5370901A (en) 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
ATE439435T1 (en) 1991-03-01 2009-08-15 Dyax Corp CHIMERIC PROTEIN COMPRISING MICROPROTEIN HAVING TWO OR MORE DISULFIDE BONDS AND FORMATIONS THEREOF
JP3672306B2 (en) 1991-04-10 2005-07-20 ザ スクリップス リサーチ インスティテュート Heterodimeric receptor library using phagemids
DE69233254T2 (en) 1991-06-14 2004-09-16 Genentech, Inc., South San Francisco Humanized Heregulin antibody
DE4122599C2 (en) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid for screening antibodies
CA2087413A1 (en) 1992-01-17 1993-07-18 Joseph R. Lakowicz Fluorescent energy transfer immunoassay
SE9201984D0 (en) 1992-06-29 1992-06-29 Pharmacia Biosensor Ab IMPROVEMENT IN OPTICAL ASSAYS
US5827690A (en) 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
US6086875A (en) 1995-01-17 2000-07-11 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of immunogens
US6030613A (en) 1995-01-17 2000-02-29 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
EP0822830B1 (en) 1995-04-27 2008-04-02 Amgen Fremont Inc. Human anti-IL-8 antibodies, derived from immunized xenomice
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
ES2301183T3 (en) 1996-12-03 2008-06-16 Amgen Fremont Inc. COMPLETELY HUMAN ANTIBODY THAT JOINS THE EGFR RECEIVER.
JP3692542B2 (en) 1997-01-21 2005-09-07 ザ ジェネラル ホスピタル コーポレーション Protein selection using RNA-protein fusions
JP2002512624A (en) 1997-05-21 2002-04-23 バイオベーション リミテッド Method for producing non-immunogenic protein
EP1068356B8 (en) 1998-04-03 2007-01-03 Adnexus Therapeutics, Inc. Addressable protein arrays
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
WO2000034317A2 (en) 1998-12-08 2000-06-15 Biovation Limited Method for reducing immunogenicity of proteins
US6472147B1 (en) 1999-05-25 2002-10-29 The Scripps Research Institute Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries
GB9928787D0 (en) 1999-12-03 2000-02-02 Medical Res Council Direct screening method
US6960178B2 (en) 2000-02-02 2005-11-01 Xepmed, Inc. Apparatus for enhanced plasmapheresis and methods thereof
US6992234B2 (en) 2000-11-06 2006-01-31 The Jackson Laboratory FcRn-based therapeutics for the treatment of auto-immune disorders
ES2327905T3 (en) 2001-10-01 2009-11-05 Dyax Corp. MULTI-CHAIN EUCARIOT PRESENTATION VECTORS AND USES OF THE SAME.
US20040005709A1 (en) 2001-10-24 2004-01-08 Hoogenboom Henricus Renerus Jacobus Mattheus Hybridization control of sequence variation
ES2362931T3 (en) 2002-03-04 2011-07-15 Imclone Llc SPECIFIC HUMAN ANTIBODIES AGAINST KDR AND USES OF THE SAME.
US7662928B2 (en) 2003-08-08 2010-02-16 The Research Foundation Of State University Of New York Anti-FcRn antibodies for treatment of auto/allo immune conditions
JP2007501847A (en) * 2003-08-08 2007-02-01 ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク Anti-FcRn antibodies for the treatment of auto / alloimmune conditions
JP2008538919A (en) 2005-04-29 2008-11-13 ザ ジャクソン ラボラトリー FcRn antibodies and uses thereof
JP2009524664A (en) * 2006-01-25 2009-07-02 ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク Anti-FCRN antibodies for the treatment of auto / alloimmune diseases
US20070181136A1 (en) 2006-02-08 2007-08-09 Gelb Michael L Oral appliance
US8359965B2 (en) 2007-09-17 2013-01-29 Oxford J Craig Apparatus and method for broad spectrum radiation attenuation
DK3059246T3 (en) 2007-09-26 2018-10-01 Chugai Pharmaceutical Co Ltd Modified constant region of an antibody
AR068723A1 (en) * 2007-10-05 2009-12-02 Glaxo Group Ltd PROTEIN THAT JOINS ANTIGENS THAT JOINS HUMAN IL-23 AND ITS USES
MX2010011679A (en) 2008-04-25 2011-05-23 Dyax Corp Antibodies against fcrn and use thereof.
US8537763B2 (en) 2008-06-30 2013-09-17 Motorola Mobility Llc Frame allocation to support legacy wireless communication protocols on uplink transmission
JP5773650B2 (en) * 2008-07-16 2015-09-02 株式会社医学生物学研究所 Anti-human CLCP1 antibody and its use
TW201029662A (en) * 2008-12-19 2010-08-16 Glaxo Group Ltd Novel antigen binding proteins
JP5717624B2 (en) * 2009-03-19 2015-05-13 中外製薬株式会社 Antibody constant region variants
MX343659B (en) 2011-06-02 2016-11-16 Dyax Corp Fc RECEPTOR BINDING PROTEINS.
BR112019025583A2 (en) 2017-06-05 2020-06-16 Janssen Biotech, Inc. GENETICALLY MODIFIED MULTI-SPECIFIC ANTIBODIES AND OTHER MULTIMERIC PROTEINS WITH ASYMMETRIC MUTATIONS IN THE CH2-CH3 REGION
SG11202011849VA (en) 2018-06-08 2020-12-30 Argenx Bvba Compositions and methods for treating immune thrombocytopenia

Also Published As

Publication number Publication date
US11739152B2 (en) 2023-08-29
US11014988B2 (en) 2021-05-25
IL229618A0 (en) 2014-01-30
JP2014523737A (en) 2014-09-18
CA2837527C (en) 2019-05-28
CN105622754A (en) 2016-06-01
SG195025A1 (en) 2013-12-30
WO2012167039A1 (en) 2012-12-06
NZ715057A (en) 2017-09-29
BR112013030352A2 (en) 2017-08-01
AU2017232160A1 (en) 2017-10-12
CN105622754B (en) 2019-12-27
US20140308206A1 (en) 2014-10-16
US20210309741A1 (en) 2021-10-07
MX343659B (en) 2016-11-16
ES2748583T3 (en) 2020-03-17
MX2013013832A (en) 2014-05-20
JP6104897B2 (en) 2017-04-05
IL229618B (en) 2018-10-31
CA2837527A1 (en) 2012-12-06
HK1213905A1 (en) 2016-07-15
EP2966089B1 (en) 2020-03-25
AU2012262007B2 (en) 2017-06-22
JP2017169559A (en) 2017-09-28
SG10201604493TA (en) 2016-07-28
AU2017232160B2 (en) 2019-12-19
JP6334763B6 (en) 2018-07-11
KR20140036267A (en) 2014-03-25
US9862768B2 (en) 2018-01-09
JP6638018B2 (en) 2020-01-29
US10479834B2 (en) 2019-11-19
EP2714084A4 (en) 2014-11-19
EP2966089A1 (en) 2016-01-13
EP2714084B1 (en) 2019-05-22
CN103619353B (en) 2016-01-06
NZ618046A (en) 2016-02-26
KR102014554B1 (en) 2019-08-26
US9359438B2 (en) 2016-06-07
JP6334763B2 (en) 2018-05-30
JP2018121657A (en) 2018-08-09
US20160304608A1 (en) 2016-10-20
US20180305454A1 (en) 2018-10-25
BR112013030352B1 (en) 2020-05-19
CN103619353A (en) 2014-03-05
EP2714084A1 (en) 2014-04-09
US20200109199A1 (en) 2020-04-09

Similar Documents

Publication Publication Date Title
IL282226A (en) St2 antigen binding proteins
HRP20181690T1 (en) Antibody fc variants
HK1213905A1 (en) Fc receptor binding proteins fc
EP2681239B8 (en) Antigen binding proteins
SG10201609665PA (en) FcɣRIIb-SPECIFIC Fc ANTIBODY
SG10201401681PA (en) Novel antigen binding proteins
HK1199042A1 (en) Cd27l antigen binding proteins cd27l
HK1198832A1 (en) Fn14 binding proteins and uses thereof fn14
EP2683742A4 (en) Npp1 fusion proteins
IL226157A0 (en) Antigen binding proteins
EP2698386A4 (en) Fusion protein
EP2793918A4 (en) Hdc-sign binding peptides
GB201103961D0 (en) Binding polypeptides
GB201007550D0 (en) Modified receptor fusion proteins
GB201004150D0 (en) Modified receptor fusion proteins
GB201114701D0 (en) Fusion proteins
GB201107189D0 (en) Fusion proteins