HK1174895A1 - Arachidonic acid analogs and methods for analgesic treatment using same - Google Patents

Arachidonic acid analogs and methods for analgesic treatment using same

Info

Publication number
HK1174895A1
HK1174895A1 HK13102048.3A HK13102048A HK1174895A1 HK 1174895 A1 HK1174895 A1 HK 1174895A1 HK 13102048 A HK13102048 A HK 13102048A HK 1174895 A1 HK1174895 A1 HK 1174895A1
Authority
HK
Hong Kong
Prior art keywords
methods
same
arachidonic acid
acid analogs
analgesic treatment
Prior art date
Application number
HK13102048.3A
Other languages
English (en)
Chinese (zh)
Inventor
.布羅斯特倫
.福爾克
Original Assignee
賽托麥蒂克斯有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 賽托麥蒂克斯有限公司 filed Critical 賽托麥蒂克斯有限公司
Publication of HK1174895A1 publication Critical patent/HK1174895A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK13102048.3A 2009-11-25 2013-02-18 Arachidonic acid analogs and methods for analgesic treatment using same HK1174895A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26443409P 2009-11-25 2009-11-25
PCT/US2010/058041 WO2011066414A1 (fr) 2009-11-25 2010-11-24 Analogues de l'acide arachidonique et procédés pour un traitement analgésique l'utilisant

Publications (1)

Publication Number Publication Date
HK1174895A1 true HK1174895A1 (en) 2013-06-21

Family

ID=43478049

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13102048.3A HK1174895A1 (en) 2009-11-25 2013-02-18 Arachidonic acid analogs and methods for analgesic treatment using same

Country Status (12)

Country Link
US (2) US8658632B2 (fr)
EP (1) EP2504311B1 (fr)
JP (1) JP5796909B2 (fr)
KR (1) KR101865194B1 (fr)
CN (1) CN102725261B (fr)
BR (1) BR112012012391A2 (fr)
CA (1) CA2781436C (fr)
DK (1) DK2504311T3 (fr)
ES (1) ES2549924T3 (fr)
HK (1) HK1174895A1 (fr)
MX (1) MX2012005689A (fr)
WO (1) WO2011066414A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2208720A1 (fr) * 2009-01-13 2010-07-21 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Nouveaux dérivés d'eicosanoïdes
KR20130108984A (ko) * 2010-05-26 2013-10-07 셀렉타 바이오사이언시즈, 인크. 합성 나노담체 조합 백신
CN103588666A (zh) * 2013-10-26 2014-02-19 史克勇 一种呈高光学纯度的化合物
CN103588663A (zh) * 2013-10-26 2014-02-19 史克勇 癌痛药
CN103588672A (zh) * 2013-10-28 2014-02-19 史克勇 一种治疗癌性疼痛的药物
CN103588667A (zh) * 2013-10-28 2014-02-19 史克勇 一种新化合物
HUE044703T2 (hu) 2014-01-22 2019-11-28 Max Delbrueck Centrum Fuer Molekulare Medizin Új CYP-eikozanoid származékok
US10966937B2 (en) * 2015-05-04 2021-04-06 Cytometix, Inc. Compositions and methods for delivery of polyunsaturated fatty acid derivatives and analogs
WO2020159576A1 (fr) * 2019-01-28 2020-08-06 Mitochondria Emotion, Inc. Activateurs de la mitofusine et leurs procédés d'utilisation
US20220387357A1 (en) * 2021-06-04 2022-12-08 Cytometix, Inc. Method of Dosing a Pain Therapeutic
US11951083B2 (en) 2022-06-08 2024-04-09 Cytometix, Inc. Methods of manufacturing 14,15-epoxyeicosatrienoic acid analogs and improved therapeutic delivery of same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US160452A (en) 1875-03-02 Improvement in caps
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4777049A (en) 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
US4663308A (en) 1984-07-18 1987-05-05 Medical College Of Ohio Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract
JPH075484B2 (ja) * 1985-03-06 1995-01-25 帝人株式会社 血液脳関門通過性医薬品組成物
IL103932A (en) * 1992-11-30 1997-02-18 Yissum Res & Dev Fatty acid and pharmaceutical compositions containing them
GB2323594A (en) * 1997-03-25 1998-09-30 Victor Martin 2-amino-alkanoic acid derivatives, 2-amino alcohols and diamines
EP1049474A4 (fr) * 1998-11-24 2004-12-29 Univ Connecticut Amides lipidiques cannabimimetiques s'utilisant comme medicaments
EA200700140A1 (ru) * 2004-07-16 2007-08-31 Янссен Фармацевтика Н.В. Димерные соединения пиперидина, пиперазина или морфолина или их семичленные аналоги, предназначенные для лечения нейродегенеративных нарушений
WO2006044381A2 (fr) 2004-10-13 2006-04-27 University Of Connecticut Ligands lipidiques cannabinergiques
EP2208720A1 (fr) * 2009-01-13 2010-07-21 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Nouveaux dérivés d'eicosanoïdes

Also Published As

Publication number Publication date
ES2549924T3 (es) 2015-11-03
US20140135401A1 (en) 2014-05-15
JP2013512255A (ja) 2013-04-11
CN102725261A (zh) 2012-10-10
US9096494B2 (en) 2015-08-04
EP2504311A1 (fr) 2012-10-03
CA2781436C (fr) 2018-01-02
US20130023510A1 (en) 2013-01-24
US8658632B2 (en) 2014-02-25
KR101865194B1 (ko) 2018-06-08
CN102725261B (zh) 2014-07-30
MX2012005689A (es) 2012-08-31
JP5796909B2 (ja) 2015-10-21
BR112012012391A2 (pt) 2020-10-20
CA2781436A1 (fr) 2011-06-03
KR20120101473A (ko) 2012-09-13
WO2011066414A1 (fr) 2011-06-03
EP2504311B1 (fr) 2015-08-12
DK2504311T3 (en) 2015-11-16

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