HK1169563A1 - 利用拉喹莫德來治療多發性硬化症 - Google Patents

利用拉喹莫德來治療多發性硬化症

Info

Publication number
HK1169563A1
HK1169563A1 HK12110013.8A HK12110013A HK1169563A1 HK 1169563 A1 HK1169563 A1 HK 1169563A1 HK 12110013 A HK12110013 A HK 12110013A HK 1169563 A1 HK1169563 A1 HK 1169563A1
Authority
HK
Hong Kong
Prior art keywords
laquinimod
treatment
multiple sclerosis
sclerosis
Prior art date
Application number
HK12110013.8A
Other languages
English (en)
Inventor
Nora Tarcic
Dan Bar-Zohar
Dina Kofler
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of HK1169563A1 publication Critical patent/HK1169563A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK12110013.8A 2009-06-19 2012-10-11 利用拉喹莫德來治療多發性硬化症 HK1169563A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26907009P 2009-06-19 2009-06-19
PCT/US2010/001759 WO2010147665A1 (en) 2009-06-19 2010-06-18 Treatment of multiple sclerosis with laquinimod

Publications (1)

Publication Number Publication Date
HK1169563A1 true HK1169563A1 (zh) 2013-02-01

Family

ID=43354572

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12110013.8A HK1169563A1 (zh) 2009-06-19 2012-10-11 利用拉喹莫德來治療多發性硬化症

Country Status (26)

Country Link
US (7) US20100322900A1 (zh)
EP (2) EP2442651B1 (zh)
JP (4) JP2012530701A (zh)
KR (2) KR20120037477A (zh)
CN (2) CN107308162A (zh)
AU (2) AU2010260455A1 (zh)
BR (1) BR112012000568A2 (zh)
CY (1) CY1116727T1 (zh)
DK (1) DK2442651T3 (zh)
EA (1) EA201270041A1 (zh)
ES (1) ES2548999T3 (zh)
HK (1) HK1169563A1 (zh)
HR (1) HRP20150988T1 (zh)
HU (1) HUE026406T2 (zh)
IL (2) IL216780A0 (zh)
ME (1) ME02282B (zh)
MX (1) MX2011013902A (zh)
NZ (1) NZ597378A (zh)
PL (1) PL2442651T3 (zh)
PT (1) PT2442651E (zh)
RS (1) RS54328B1 (zh)
SG (2) SG176840A1 (zh)
SI (1) SI2442651T1 (zh)
SM (1) SMT201500262B (zh)
WO (1) WO2010147665A1 (zh)
ZA (1) ZA201200029B (zh)

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US8501766B2 (en) * 2010-03-03 2013-08-06 Teva Pharmaceutical Industries Ltd. Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
SG183515A1 (en) * 2010-03-03 2012-10-30 Teva Pharma Treatment of lupus arthritis using laquinimod
EP2597954A4 (en) 2010-07-09 2014-01-01 Teva Pharma DEUTERATED N-ETHYL-N-PHENYL-1,2-DIHYDRO-4-HYDROXY-5-CHLORO-1-METHYL-2-OXOCHINOLINE-3-CARBOXAMIDE, SALT THEREOF AND APPLICATIONS THEREOF
AU2011338647A1 (en) * 2010-12-07 2013-07-04 Teva Pharmaceutical Industries Ltd. Use of laquinimod for reducing fatigue, improving functional status, and improving quality of life in multiple sclerosis patients
MX2014001050A (es) * 2011-07-28 2014-04-14 Teva Pharma Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatiramero.
BR112014002092A2 (pt) * 2011-07-28 2017-02-21 Teva Pharma tratamento de esclerose múltipla com combinação de laquinimod e interferon-beta
EA201490748A1 (ru) * 2011-10-12 2014-12-30 Тева Фармасьютикал Индастриз Лтд. Лечение рассеянного склероза комбинацией лахинимода и финголимода
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US20130259856A1 (en) * 2012-03-27 2013-10-03 Teva Pharmaceutical Industries, Ltd. Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate
AR090885A1 (es) * 2012-05-02 2014-12-10 Teva Pharma Uso de laquinimod en alta dosis para el tratamiento de la esclerosis multiple
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TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
UY34896A (es) * 2012-07-12 2014-02-28 Teva Pharma Tratamiento de la esclerosis múltiple con una combinación de laquinimod y fampridina
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療gaba媒介之疾病之拉喹莫德(laquinimod)
US20140107154A1 (en) * 2012-10-12 2014-04-17 Teva Pharmaceutical Industries, Ltd. Laquinimod for reducing thalamic damage in multiple sclerosis
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US8501766B2 (en) * 2010-03-03 2013-08-06 Teva Pharmaceutical Industries Ltd. Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
SG183515A1 (en) * 2010-03-03 2012-10-30 Teva Pharma Treatment of lupus arthritis using laquinimod
CN102791130B (zh) * 2010-03-03 2015-02-25 泰华制药工业有限公司 使用拉喹莫德治疗狼疮肾炎
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Also Published As

Publication number Publication date
EA201270041A1 (ru) 2012-06-29
RS54328B1 (en) 2016-02-29
ZA201200029B (en) 2013-03-27
JP2012530701A (ja) 2012-12-06
US20170128435A1 (en) 2017-05-11
SI2442651T1 (sl) 2015-10-30
SG10201403397TA (en) 2014-10-30
IL252699A0 (en) 2017-07-31
HRP20150988T1 (hr) 2015-11-20
JP2015107981A (ja) 2015-06-11
EP2442651B1 (en) 2015-07-29
EP2442651A4 (en) 2012-10-31
EP3028572A1 (en) 2016-06-08
AU2016216586A1 (en) 2016-09-01
US20150164880A1 (en) 2015-06-18
PL2442651T3 (pl) 2015-12-31
PT2442651E (pt) 2015-10-22
ME02282B (me) 2016-02-20
HUE026406T2 (en) 2016-06-28
US20130272996A1 (en) 2013-10-17
MX2011013902A (es) 2012-02-23
US20180042916A1 (en) 2018-02-15
DK2442651T3 (en) 2015-09-21
BR112012000568A2 (pt) 2015-10-06
AU2010260455A1 (en) 2012-02-02
SG176840A1 (en) 2012-02-28
NZ597378A (en) 2014-08-29
JP2016199555A (ja) 2016-12-01
IL216780A0 (en) 2012-02-29
CN107308162A (zh) 2017-11-03
ES2548999T3 (es) 2015-10-22
US20160082001A1 (en) 2016-03-24
CN102802415A (zh) 2012-11-28
US20140105850A1 (en) 2014-04-17
CY1116727T1 (el) 2017-03-15
SMT201500262B (it) 2016-01-08
KR20120037477A (ko) 2012-04-19
WO2010147665A1 (en) 2010-12-23
KR20170109091A (ko) 2017-09-27
JP2018021045A (ja) 2018-02-08
US20100322900A1 (en) 2010-12-23
EP2442651A1 (en) 2012-04-25

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190616